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Meet Our Members

The Center for Respiratory Biology and Therapeutics brings together basic science and clinical researchers across Seattle Children’s in pulmonary, otolaryngology, surgery, critical care, neonatology, respiratory therapy and pathology.

Our researchers have made scientific discoveries that have changed to lives of children with cystic fibrosis, asthma and other respiratory conditions and diseases.

Membership with the Center for Respiratory Biology and Therapeutics is available for all Seattle Children's investigators. To learn more about becoming a member of the center or inquire about collaboration opportunities, send us an email.

Leadership

Jason Debley, MD, MPH

Dr. Jason DebleyJason S. Debley, MD, MPH, interim director of the Center for Respiratory Biology and Therapeutics, is an attending physician in the Pulmonary and Sleep Medicine Division at Seattle Children's Hospital and a professor in the Department of Pediatrics at the University of Washington School of Medicine. He received his MD from Northwestern University Medical School and completed his pediatrics internship and residency at Children’s Memorial Hospital in Chicago, Illinois. He completed his pediatric pulmonary fellowship at Seattle Children’s and earned an MPH from the University of Washington. He has clinical expertise in severe asthma, recurrent wheezing of early childhood, bronchopulmonary dysplasia, restrictive lung diseases of childhood and the management of chronic respiratory failure.

As a physician-scientist Dr. Debley's research has spanned clinical, epidemiologic, basic and mechanistic patient-oriented translational asthma research. His work over the past two decades has concentrated on investigation of the role of the airway epithelium in asthma pathobiology, with focus areas including study of innate immune responses of airway epithelial cells to respiratory viruses and aberrant epithelial regulation of airway remodeling responses. He built a translational research program wherein primary bronchial airway epithelial cells are obtained from children with asthma and healthy children undergoing elective surgical procedures at Seattle Children’s Hospital. This infrastructure is a unique resource in the United States, providing a steady source of primary bronchial airway epithelial cells from carefully characterized children with asthma that are used to conduct mechanistic research to advance our understanding of the role of airway epithelial responses in asthma and to identify novel therapeutic targets.

Center for Respiratory Biology and Therapeutics

For questions or inquiries,
email: CRBT@seattlechildrens.org.

Physical Address

1900 Ninth Ave.
Seattle, WA 98101

Mailing Address

M/S JMB-7
1900 Ninth Ave.
Seattle, WA 98101