Unraveling the mechanisms beneath neurological, neurodevelopmental and neuropsychiatric disorders

Center for Integrative Brain Research

We are a diverse group of researchers working to integrate knowledge at the genetic, molecular, cellular, network and behavioral levels to better understand neuronal functions and brain-related diseases.

Featured Research

Discovering Patterns in the Neural Activity Powering Breathing

Scientists in Seattle Children’s Center for Integrative Brain Research produced a first-ever population-level analysis of neural activity underlying breathing.

Sedensky, Morgan Honored by American Society of Anesthesiologists

Drs. Marge Sedensky and Phil Morgan, Center for Integrative Brain Research, recognized with national Excellence in Research award for their pioneering studies in how anesthetics work and making them safer for children with mitochondrial disease.

How the Brain Learns to Find Its Next Reward

Dr. Jonathan Tang, Center for Integrative Brain Research, and colleagues published insights into how our brains learn and adapt through trial and error, with implications for education and artificial intelligence.

Brainstem Region Revealed to Play Role in Regulating Swallow, Breathing

Seattle Children’s researchers revealed novel insights about PiCo, a brainstem region that aids the coordination of swallowing and breathing.

Anti-clotting pill may usurp current treatments in kids

Oct. 31, 2022 – Dr. Michael Portman in the Center for Integrative Brain Research and Division of Cardiology, along with an international research team, tested the safety and effectiveness of an anti-clotting pill in children.

Sleuthing the Source of a New Neurodevelopmental Disorder

Oct. 6, 2022 – Dr. Brock Grill and his lab members in the Center for Integrative Brain Research collaborated with an international research team to identify the molecular genetic cause of a new neurodevelopmental disorder.

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More than half of the kids who come to Seattle Children’s will live with conditions that they will have for the rest of their lives. Research can give them a different future. Under designation, select “Other” and enter Center for Integrative Brain Research.

Center for Integrative Brain Research

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