Clinical Trials and Research Studies

After becoming pregnant again, Lisa and her husband, Ty, learned their unborn son had the same genetic disorder that took the life of their firstborn daughter. Today, thanks to research and the care they received here, their son Colton is a thriving 6-year-old.

After winning the Food Network’s Chopped Jr. reality TV cooking competition, Fuller Goldsmith, 16, was well on his way to achieving his dreams of becoming a professional chef. Then Fuller learned his cancer had returned for a fourth time. He enrolled in the PLAT-05 clinical trial at Seattle Children's. Today, more than a year since receiving his CAR T cells, Fuller remains in remission.

For much of the last decade, Dr. David Rawlings, director of Seattle Children’s Research Institute’s Center for Immunity and Immunotherapies, has dreamed of developing a therapy for children with type 1 diabetes that doesn’t involve insulin injections but uses a person’s own immune cells to target and treat the disease. Now, new research and a fresh infusion of funding bring this dream closer to reality.

Marcus was born with hypoplastic left heart syndrome, a rare and serious birth defect that occurs when the left side of the heart is not fully developed. He had three surgeries to treat his heart condition and participated in a clinical trial for an investigational medication.

Ellie participated in a clinical trial for Trikafta, a breakthrough cystic fibrosis therapy approved by the U.S. Food and Drug Administration in 2019.