Clinical Trials and Research Studies

After winning the Food Network’s Chopped Jr. reality TV cooking competition, Fuller Goldsmith, 16, was well on his way to achieving his dreams of becoming a professional chef. Then Fuller learned his cancer had returned for a fourth time. He enrolled in the PLAT-05 clinical trial at Seattle Children's. Today, more than a year since receiving his CAR T cells, Fuller remains in remission.

For much of the last decade, Dr. David Rawlings, director of Seattle Children’s Research Institute’s Center for Immunity and Immunotherapies, has dreamed of developing a therapy for children with type 1 diabetes that doesn’t involve insulin injections but uses a person’s own immune cells to target and treat the disease. Now, new research and a fresh infusion of funding bring this dream closer to reality.

Marcus was born with hypoplastic left heart syndrome, a rare and serious birth defect that occurs when the left side of the heart is not fully developed. He had three surgeries to treat his heart condition and participated in a clinical trial for an investigational medication.

Ellie participated in a clinical trial for Trikafta, a breakthrough cystic fibrosis therapy approved by the U.S. Food and Drug Administration in 2019.