The goal of the James lab is to learn how human B cells normally differentiate into long-lived antibody-secreting plasma cells. We would like to better understand how B cell differentiation becomes dysregulated and contributes to disease, including lymphoma, primary immune deficiency and lupus. Ultimately, we will use what we learn to inform diagnoses of B cell related disease and to develop B cell-based therapies.
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Richard G. James, PhD
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Center for Immunity and Immunotherapies
1900 Ninth Ave.
Seattle, WA 98101