Our Labs

Acharya Lab

The Acharya lab studies how immune cells integrate signals from pathogens and their environment to produce effective immunity against pathogens while maintaining tolerance to self-derived antigens.

Allenspach Lab

The Allenspach Lab is focused on translational work to understand immune dysregulation disorders - those with overlapping immunodeficiency and autoimmune features. The lab combines genetic and deep immunophenotyping techniques to identify novel pathogenic variants and use human samples and animal models to probe the mechanism of dysregulation.

Debley Lab

The Debley Lab is engaged in an array of translational research investigating the role of the airway epithelium in childhood asthma.

Jackson Lab

The Jackson Lab studies the immune mechanisms underlying the development of systemic autoimmune diseases, focusing in particular on the role of B cells in systemic lupus erythematosus (SLE). The lab uses various chimeric and genetic knock-in murine strains to model the biology of human autoimmune diseases.

James Lab

The James Lab is interested in uncovering biochemical mechanisms that contribute to drug resistance and to immunological disease. To do so, we investigate many features of protein behavior, including their impact on differentiation, their interactions with other molecules and whether mutation regulates these processes.

Related topics: Immunology, B cells, genetic variation

Miao Lab

The Miao Lab is pursuing safer, more effective treatments for hemophilia. Our current work focuses on innovative gene therapy approaches.

Piliponsky Lab

The Piliponsky Lab studies inflammatory responses involving mast cells and myeloid cells.

Zheng Lab

The Zheng Lab is dedicated towards understanding the pathways of disease in pediatric gastrointestinal autoimmune conditions such as Crohn’s disease (CD) and ulcerative colitis (UC).