Harnessing the Power of the Immune System

Center for Immunity and Immunotherapies

Our goal is to learn powerful insights into the immune system by the study of disease. We use these insights to pursue innovative therapies for rare and common pediatric disease.

>75 Immune diseases actively managed at Seattle Children's Immunology Clinic 404 Primary Immune Deficiency Diseases

25 Conditions have indication for cellular therapy

Featured Research

Finding an Allergy Brake

May 16, 2023 – Researchers in the Center for Immunity and Immunotherapies have discovered a new mechanism in human mast cells: They express an inhibitory receptor, Siglec-9, that can act as a brake on their activation.

Children’s Researchers Share Progress at ASGCT Annual Meeting

May 16, 2023 - Key findings from the Center for Immunity and Immunotherapies highlighted at the American Society of Gene and Cell Therapy’s Annual Meeting from May 16 to 20 in Los Angeles.

Murdock Grant Enables New Cell Analyzer as Shared Resource

Apr. 24, 2023 - An M.J. Murdock Charitable Trust grant awarded to Drs. Rhea Coler and Shaun Jackson facilitates cell analyzer acquisition for the research institute’s Integrated Flow Cytometry Core.

Seattle Children's Research Division Featured on Voice of America

Voice of America has published a feature episode looking at innovative research underway at Seattle Children's Research Division, specifically CAR T-cell immunotherapy and protein, cell and gene therapy. Watch the episode.

Engineering B Cells for Future Therapies

Oct. 6, 2022 – Nature Communications published findings by Seattle Children’s Research Institute’s Drs. Richard James and David Rawlings about long-lived engineered B cells to deliver protein therapies.

Explore this Center

Participate in Research

We are testing whether gene therapy can be used to treat male infants with X-linked Severe Combined Immunodeficiency (X-linked SCID).

Donate to the Center

The Center for Immunity and Immunotherapies develops breakthrough tests and treatments for children with severe – and often fatal – immune disorders.

Center for Immunity and Immunotherapies

For questions or inquiries,
email: ciitadmin@seattlechildrens.org.

Physical Address

1900 Ninth Ave.
Seattle, WA 98101

Mailing Address

PO Box 5371
Seattle, WA 98145-5005