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Brain Tumor Resource Lab

Best characterized models of the Brain Tumor Resource Lab.png

The Brain Tumor Resource Lab strives to generate and distribute patient-derived xenograft models and cell lines. Our focus is on pediatric brain tumors.

The figure at right depicts the best-characterized models for comparison. Click on it for a larger version.

Please note that the tissue culture lines should not be implanted into mice and patient-derived xenograft cell lines should not be used for tissue culture.

These resources are for academic use only. Please contact us if you are interested in other uses.

Similar to ATCC, the only way to obtain these lines is to place an order through this site. This ensures that we can contact you if important information needs to be conveyed, that you understand that the lines cannot be shared, that a material transfer agreement is in place and that we can track how these lines are used to benefit science and medicine.

We gratefully acknowledge funding from the National Institutes of Health, Seattle Run of Hope, the German Cancer Consortium (DKTK), and the German Cancer Research Center (DKFZ), Heidelberg, Germany.

Order Cell Lines Contact Us

Resources

BTRL Cell Line Information

Note: Please check the order sheet to see the availability for the cell lines below. Some cell lines might not be immediately available and will be processed on an as-available basis.

Medulloblastoma Lines

Med-113FH cellsTumor Classification

Medulloblastoma, Group 3: 17p, 9q, PTCH1

Available As

Mouse Xenograft

See Details

Med-114FH cellsTumor Classification

Medulloblastoma, Group 3: 17p

Available As

Mouse Xenograft
mCherry/luciferase Mouse Xenograft
Tissue Culture Line

See Details

Med-1512FH cellsTumor Classification

Medulloblastoma, Group 4: MYCN

Available As

Mouse Xenograft

See Details

Med-1712FH cellsTumor Classification

Medulloblastoma, SHH: 9q, PTCH1

Available As

Mouse Xenograft

See Details

Tumor Classification

Medulloblastoma, Group 3: 17p

Available As

Mouse Xenograft

See Details

Med-210FH cellsTumor Classification

Medulloblastoma, Group 3: 17q, 9q

Available As

Mouse Xenograft

See Details

Med-2112FH cellsTumor Classification

Medulloblastoma, Group 3: MYC, 17p, 17q, 9p

Available As

Mouse Xenograft
mCherry/luciferase Mouse Xenograft
Tissue culture line available

See Details

Med-211FH cellsTumor Classification

Medulloblastoma, Group 3: 17p

Available As

Mouse Xenograft

See Details

Med-2312FH cellsTumor Classification

Medulloblastoma, Group 4: 17p, 17q, 9q

Available As

Mouse Xenograft

See Details

Med-314FH cellsTumor Classification

Medulloblastoma, SHH: TP53, MYCN, GLI2, 17p, 17q, 9q

Available As

Mouse Xenograft
mCherry/luciferase Mouse Xenograft

See Details

Med-411FH cellsTumor Classification

Medulloblastoma, Group 3: MYC, 17q, 17p

Available As

Mouse Xenograft
mCherry/luciferase Mouse Xenograft
Tissue culture line available

See Details

Med-610FH cellsTumor Classification

Medulloblastoma, Group 4: 17q, PRDM6

Available As

Mouse Xenograft

See Details

Has not yet been characterized.

Med-813FH cellsTumor Classification

Medulloblastoma, SHH: TP53, MYCN, GLI2, 17p, 17q, 9q

Available As

Mouse Xenograft

See Details

Med-913FH cellsTumor Classification

Medulloblastoma, WNT: CTNNB1

Available As

Mouse Xenograft

See Details

PBT-07FH cellsTumor Classification

Medulloblastoma, Group 3: KBTBD4, 17p, 17q, 9q

Available As

Mouse Xenograft

See Details

High Grade Glioma Lines

PBT-01FH cellsTumor Classification

High Grade Glioma, K27: EGFR, H3FA/HIST1H3B

Available As

Mouse Xenograft

See Details

PBT-02FH cellsTumor Classification

High Grade Glioma, pedRTK1: CDK4, FGFR1-4, MDM2

Available As

Mouse Xenograft

See Details

Tumor Classification

High Grade Glioma, K27: ATRX, H3FA/HIST1H3B, SETD1A, TP53

Available As

Mouse Xenograft

See Details

PBT-04FH cellsTumor Classification

High Grade Glioma, MYCN: ID2, MYCN

Available As

Mouse Xenograft

See Details

PBT-05FH cellsTumor Classification

High Grade Glioma, MYCN: ID2, MYCN, EGFR, PIK3R1, MGMT methylation

Available As

Mouse Xenograft

See Details

Tissue Culture

See Details

PBT-06FH cellsTumor Classification

High Grade Glioma, PedRTK1: CDK4, PDGFRA, TERT, TP53

Available As

Mouse Xenograft

See Details

GBM-311FH cellsTumor Classification

High Grade Glioma, pedRTK1: ATRX, EGFR, FGFR1-4, MGMT metylation, MSH2, hypermutator

Available As

Mouse Xenograft

See Details

Tumor Classification

High Grade Glioma, PedTRK1: CDKN2A/B

Available As

Tissue Culture

See Details

GBM-611FH cellsTumor Classification

High Grade Glioma, pedRTK1: ATRX, EGFR, FGFR1-4, MSH2, hypermutator

Available As

Mouse Xenograft

See Details

Tumor Classification

High Grade Glioma

Available As

Mouse Xenograft

Has not been characterized, TC line only

Tumor Classification

Astrocytoma

Has not been characterized, TC line only

Tumor Classification

High Grade Glioma

Tumor Classification

High Grade Glioma, pedRTK2: BRAF, CDKN2A/B

See Details

Tumor Classification

DMG H3.3K27M

See Details

Tumor Classification

DMG H3wt: hypermutator

See Details

Tumor Classification

DMG H3.1 K27M

See Details

Tumor Classification

DMG H3.3K27M

See Details

Ependymoma Lines

EPD-210FH cellsTumor Classification

Ependymoma, PFA: 1q

Available As

Mouse Xenograft

See Details

Tissue Culture Line

See Details

Tumor Classification

Ependymoma

Both Tissue Culture and PDX cell lines available

EPD-410FH cellsTumor Classification

Ependymoma

Available As

PDX Cell Line

EPD-613FH cellsTumor Classification

Ependymoma, RELA fusion: CDKN2A/B, RELA

Available As

Mouse Xenograft

See Details

Tumor Classification

Ependymoma, PFA: 1q

Available As

Mouse Xenograft

See Details

Pineoblastoma Cell Lines

PBT-08FH cellsTumor Classification

Pineoblastoma

Available As

Mouse Xenograft

See Details

Neuroblastoma Cell Lines

Patient Derived Xenograft grown in Flank.

Atypical Teratoid Rhabdoid Tumor Cell Lines

ATRT-310FH/ATRT-333FH cellsTumor Classification

Atypical Teratoid Rhabdoid, SHH: SMARCB1

Available As

Mouse Xenograft

See Details

Tissue Culture Line

See Details

Tumor Classification

Atypical Teratoid Rhabdoid, SHH: SMARCB1

Available As

Mouse Xenograft

See Details

ATRT-312FH cellsTumor Classification

Atypical Teratoid Rhabdoid, MYC: SMARCB1

Available As

Mouse Xenograft

See Details

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