Christian L Roth, MD

  • Biography

    Board Certification(s)

    Neonatal-Perinatal Medicine
    Pediatric Endocrinology


    Ruprecht-Karls-Universitaet Heidelberg, D-6900 Heidelberg

    Clinical Interests

    Clinical Interests: Children with endocrine disorders and diabetes mellitus

    Research Interests: Obesity studies, including appetite-regulating peptides, factors of the metabolic syndrome, hypothalamic obesity and genetic and environmental factors involved in the onset of puberty

    Research Description

    My clinical work is based at Seattle Children’s Hospital as an attending of the Endocrine Division. This work involves the care of children with early onset of morbid obesity, children with brain tumors and complex endocrine disturbances such as hypothalamic obesity, as well as children with other endocrine disorders.

    Most of my research to date has focused on clinical obesity studies and translational studies regarding metabolic changes associated with obesity. I have extensive experience in evaluating metabolic risk factors before and after weight loss due to lifestyle intervention. I also have experience in drug intervention studies and in connecting clinical studies with lab-based research. In my lab, which is located at Seattle Children's Research Institute, we analyze different peptides involved in the regulation of food intake and energy homeostasis as well as inflammatory markers. We also do functional neuroimaging studies in lean and obese children to better understand reward circuits and the driving forces of excessive eating and weight gain. I am a principal investigator and currently lead two NIH-funded clinical obesity intervention studies in children.

    Research Focus Area

    Biochemistry, Diabetes, Endocrinology / Metabolism

  • Patient Testimonials

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  • Awards and Honors

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  • Publications

  • Presentations

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  • Research Funding

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  • Clinical Trials and Research Studies

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    No clinical trials found for Christian L Roth, MD.