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Informational Alert

Learn about progress on health equity and anti-racism efforts in Seattle Children’s fourth quarterly report.

Research Projects

Clinical biomarkers of CAR T cell neurotoxicity

This project investigates whether biomarkers in serum, cerebrospinal fluid, or on brain imaging can predict neurotoxicity risk and measure brain injury in pediatric cancer immunotherapy patients.

Mechanism of CAR T cell neurotoxicity

We study the effects of CD19-directed CAR T cell therapy on the brain microvasculature in an immunocompetent mouse model.

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