The Center for Developmental Biology and Regenerative Medicine (CDBRM) studies the body's response to injury at multiple levels, including molecular, cellular, tissue and whole-organ. CDBRM uses the Beier Lab's research to develop therapeutic interventions that will ultimately help the body repair itself.
The Beier Lab studies organ development and repair using genetic and genomic analysis of model systems and human birth defect syndromes.
The Bennett Lab investigates the contribution of post-zygotic mutations on human development and birth defects, with a focus on vascular malformations.
The Cherry Lab investigates how the visual system develops, and how genetic variations contribute to blindness and other visual disorders.
The Cunningham Lab studies the fundamental mechanisms behind craniosynostosis and other malformations to improve care for patients with craniofacial conditions.
The Gumbiner Lab studies how tissues and organs are built from collections of individual cells.T his leads to discoveries about how animals and humans develop, and how their tissues are maintained, repaired and regenerated.
Hing Studies investigates the genetic causes of craniofacial disorders to improve the diagnosis and management of infants, children and adolescents with craniofacial and genetic conditions.
The Luquetti Lab studies the genetics and epidemiology of craniofacial malformations to identify their causes and develop research methods that can be used to study a wide variety of birth defects.
The Maga Lab investigates the contributions of genetic and environmental factors responsible for human malformations, specifically craniofacial disorders and normal phenotypic variation. The lab is currently unraveling the epigenetic changes – alternations in the genome due to environmental factors as opposed to mutations – that contribute to fetal alcohol spectrum disorders.
The Majesky Lab uses molecular, biological and developmental genetic approaches to address fundamental questions in the development and differentiation of blood vessels. The goal is to understand the molecular mechanisms involved in the embryonic development of the heart and vascular system to discover and develop applications for stem and progenitor cell-based therapies.
The Maves Lab investigates how heart and muscle cells develop in the hope of uncovering new treatments for muscular dystrophy and heart disorders.
The Nigam Lab aims to improve the care of young cardiac patients by discovering and applying innovative solutions for hypoplastic left heart syndrome; improving outcomes for children undergoing cardiac surgery with cardiopulmonary bypass and mechanical circulatory support; and inventing new tools and processes that make surgery management safer and easier.
The Rose Lab focuses on the Kaposi's sarcoma–associated herpesvirus/human herpesvirus 8 and its transmission and pathogenic role in AIDS-related malignancies. Research areas of focus include virology, specifically viral transmission and dissemination; viral diagnostics; viral persistence and reservoirs; viral infection–related cancers and animal models of human disease.
The Shih Lab uses advanced optical imaging to study neurovascular function in the living brain. Our goal is to better understand how blood flows through the brain by watching and learning from model organisms.
The Yu Lab studies how craniofacial malformations occur, opening the door to new ways to diagnose, prevent and treat them.