Diabetes Research

Current Research Studies

Help us answer questions about childhood health and illness, and help other children in the future. Learn more.

SEARCH for Diabetes in Youth

With funding from the Centers for Disease Control and Prevention (CDC) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the SEARCH study was developed to learn more about the nature and extent of diabetes in youth in the United States. Seattle Children's is one of five clinical sites across the country. The study is the largest ever study of diabetes in children and young adults in the country.

The SEARCH study is now in its 15th year, and has an enrollment of more than 26,000 participants nationwide. The newest phase of the study began in September 2010 and will last until 2015. It includes both a registry study to look at the trends in diabetes incidence, and a cohort component to examine quality of care, barriers to care, transition to the adult health care system and various risk factors for acute and chronic complications.

If you have been recently diagnosed with diabetes and live in the Puget Sound area, we will invite you to complete a short survey about your family and your experiences with diabetes. You would receive a $10 gift card as a thank you for completing this survey. If you are diagnosed in 2012, we would invite you to complete a brief visit which includes specimen collection, physical exam and questionnaires.

If you have previously completed a SEARCH visit and have at least five years' duration of diabetes, you may be eligible to complete a follow-up "cohort" visit. This visit will be similar to the visits you have already completed, with the addition of some questionnaires and other measurements.

Your SEARCH visit would be scheduled at a time and place that are convenient for you. We have clinics in Seattle, Bellevue, Tacoma, Federal Way, Olympia, Silverdale and Everett.

Please contact the diabetes research team at 206-987-2540 for more information about the SEARCH study.

Juvenile Diabetes Research Foundation (JDRF) Study

The main goal for this study is to learn more about what causes autoimmune disease, especially diabetes. To help answer this question we will gather information about:

  • History of the disease course
  • Family history of diabetes and other autoimmune diseases
  • Specific proteins, cells and genes that reflect the body's immune system activity
  • Measures of the body's insulin production

With this information we hope to identify markers that would allow us to treat diabetes in youth effectively. Participants will be compensated for their time with a $25 gift card. This visit can only take place at Seattle Children's.

TrialNet Study of Natural History

Type 1 Diabetes TrialNet is a network of 18 clinical centers dedicated to conducting diabetes prevention research and studying intervention therapies for children and adults with newly diagnosed diabetes. The TrialNet Natural History study will enable us to learn more about risk factors associated with the development of type 1 diabetes. We are screening relatives of people with type 1 diabetes to find if their family members are at risk for developing diabetes. Screening involves a simple blood test for the presence of diabetes-related autoantibodies that may appear years before type 1 diabetes develops.

This visit can either take place at Seattle Children's or at Children's clinics in Federal Way, Olympia, Everett or Bellevue.

The T1D Exchange Type I Diabetes Network

The purpose of the study is to improve the care of persons with type 1 diabetes through sharing of best practices by collecting data in a common data repository. Patients with Type 1 diabetes are eligible to participate. Participants will complete a short data collection form. Information will also be collected from your medical record. A $20 gift card will be given as a thank-you.