Cystic Fibrosis Research

Meet Our Team


Our primary cystic fibrosis (CF) investigators include clinicians, laboratory scientists and epidemiologists, each of whom makes valuable contributions to our program. Read their individual provider profiles to learn more about their expertise and research interests.

Maida Chen, MD 
Assistant Professor, Pulmonary and Sleep Medicine

Dr. Maida Chen's research interests focus on respiratory control disorders and sleep-disordered breathing in special-needs populations, including those with fetal alcohol spectrum disorders, obesity and craniofacial anomalies.

Ron Gibson, MD, PhD 
Professor of Pediatrics, Pulmonary and Sleep Medicine

Dr. Ron Gibson's primary research focuses on early events in the pathogenesis of lung disease in CF, with a focus on the risk factors for and the treatment of Pseudomonas aeruginosa airway infections in young children with CF. He has been lead and co-investigator for several phase I to phase III clinical trials involving novel antimicrobial agents, anti-inflammatory compounds and modulators of ion transport.

Nicole Hamblett, PhD
Research Associate Professor, Pulmonary and Sleep Medicine

Dr. Nicole Hamblett's research interests include the design and analysis of clinical trials, with emphasis in the pediatric and orphan disease setting. She is involved in the development of new clinical outcome measures for CF and, in particular, the validation of biomarkers to enable early evaluation of new therapies. Hamblett also provides statistical training to clinical researchers and scientists.

Luke Hoffman, MD, PhD 
Assistant Professor, Pulmonary and Sleep Medicine

Dr. Luke Hoffman's research focuses on chronic lung infections, particularly in patients with CF. Hoffman is working to understand why chronic lung infections are so difficult to treat and how to improve current treatments. His areas of clinical expertise include asthma, CF, bronchopulmonary dysplasia, restrictive lung diseases and the pulmonary complications of neuromuscular disease.

Bonnie Ramsey, MD 
Professor of Pediatrics, Pulmonary and Sleep Medicine

Dr. Bonnie Ramsey's research focuses on clinical care and developing new therapies for CF patients. Ramsey is a pioneer in developing new treatments to meet the needs of the CF community and is the lead investigator of the TOBI™ (Tobramycin Solution for Inhalation) clinical trial. Her research interests also include the ethics of pediatric clinical research.

Margaret Rosenfeld, MD, MPH 
Associate Professor of Pediatrics

Dr. Margaret Rosenfeld's research focuses on the assessment and treatment of early CF lung disease, including infant and preschool lung function tests, determining risk factors for early acquisition of Pseudomonas aeruginosa and clinical trials in infants with CF. She is also an investigator in a national network investigating rare disorders of mucociliary clearance, including primary ciliary dyskinesia.

Research Coordinators

Our research coordinators are usually the first point of contact for any clinical trial. Please contact one of them to learn more about a specific study or taking part in CF clinical research in general.

Sharon McNamara, MN 
Lead Research Nurse Coordinator

Alan Genatossio, BSN 
Research Nurse Coordinator

Janine Jijina, BS 
Research Associate