Tools and Data

Diagram of regulatory variants

aFC-n

aFC-n is a multi-eQTL generalization of the allelic fold change (aFC) method for estimating regulatory effect sizes. We provide effect size estimates for GTEx tissues in a Zenodo repository.

GitHub | Zenodo | Paper

ANEVA illustration

ANEVA

ANEVA (analysis of expression variation) quantifies genetic variation in gene dosage from allelic expression (AE) data in a population. ANEVA-DOT applies these variance estimates in a dosage outlier test for use in rare disease diagnostic pipelines.

ANEVA code | ANEVA-DOT code | Paper

 

Pantry illustration

Pantry

Pantry is a framework to efficiently generate diverse RNA phenotypes from RNA sequencing data and perform downstream integrative analyses with genetic data. We provide results for GTEx tissues and Geuvadis in a Zenodo repository, and a web portal for exploring the results.

Pantry Portal | GitHub | Zenodo | Paper

RatGTEx Illustration

RatGTEx

RatGTEx provides gene expression, eQTL, and sQTL data for multiple rat tissues, with particular focus on the brain and applications to behavioral research in outbred rats.

RatGTEx Portal | Rat TWAS Hub | GitHub | Pilot paper | NIDA Center

Contact Us

Pejman Mohammadi, PhD

For questions or inquiries,
email: [email protected]

Physical Address

Center for Immunity and Immunotherapies
1920 Terry Ave.
Seattle, WA 98101