Listed below is a selection of recent publications from the Stuart Lab. See a list of Dr. Stuart’s publications on PubMed.

Identification by Random Mutagenesis of Functional Domains in KREPB5 That Differentially Affect RNA Editing Between Life Cycle Stages of Trypanosoma bruceiMcDermott SM, Carnes J, Stuart K. Mol Cell Biol. 2015 Dec;35(23):3945-61.

Differential Editosome Protein Function Between Life Cycle Stages of Trypanosoma bruceiMcDermott SM, Guo X, Carnes J, Stuart KJ. Biol Chem. 2015 Oct 9;290(41):24914-31 

Inositol Phosphate Pathway Controls Transcription of Telomeric Expression Sites in Trypanosomes.  Cestari I, Stuart K. Proc Natl Acad Sci U S A. 2015 May 26;112(21):E2803-12.

Bloodstream form Trypanosoma brucei do not Require mRPN1 for gRNA ProcessingCarnes J, Lerch M, Kurtz I, Stuart K. RNA. 2015 Jan;21(1):28-35.

Computer-aided Discovery of Trypanosoma brucei RNA-editing Terminal Uridylyl Transferase 2 InhibitorsDemir O, Labaied M, Merritt C, Stuart K, Amaro RE. Chem Biol Drug Des. 2014 Aug;84(2):131-9.

Genetic Validation of Aminoacyl-tRNA Synthetases as Drug Targets in Trypanosoma bruceiSavitha Kalidas,Igor Cestari, Severine Monnerat, Qiong Li, Sandesh Regmi, Nicholas Hasle, Mehdi Labaied, Marilyn Parsons, Kenneth Stuart, and Margaret A. Phillips. Eukaryot Cell. 2014 Apr; 13(4): 504–516.

N1,N1-dimethyl-N3-(3-(trifluoromethyl)phenethyl)propane-1,3-diamine, a new lead for the treatment of human African trypanosomiasisNgoc B. Pham,Sophie Deydier, Mehdi Labaied, Séverine Monnerat, Kenneth Stuart, and Ronald J. Quinn. Eur J Med Chem. 2014 Mar 3; 74: 541–551.

A Multiple Aminoacyl-tRNA Synthetase Complex That Enhances tRNA-Aminoacylation in African TrypanosomesIgor Cestari, Savitha Kalidas, Severine Monnerat, Atashi Anupama, Margaret A. Phillips, and Kenneth StuartMol Cell Biol. 2013 Dec; 33(24): 4872–4888