Jay F Sarthy, MD, PhD

Jay F Sarthy, MD, PhD


  • Children's Title: Attending Physician, Pediatric Bone Marrow Transplantation Service, Cancer and Blood Disorders Center
  • Academic Title: Assistant Professor, Department of Pediatrics, University of Washington School of Medicine
  • Research Title: Investigator, Ben Towne Center for Childhood Cancer Research and Assistant Director of Epigenetics
  • Research Center: Ben Towne Center for Childhood Cancer Research
  • On Staff Since: December 2017
"My approach to care is based on building trust with you and your child. I’m there for each family through thick and thin, no matter how treatment is going or what the result is."
  • Biography

    Dr. Jay Sarthy is a hematologist-oncologist who specializes in pediatric bone marrow transplantation for children with blood cancers and rare genetic conditions, such as telomere syndromes. 

    In addition to working closely with patients and families, Dr. Sarthy studies pediatric cancer epigenetics — how changes in the way genes function can derail normal development, giving rise to cancer. The goal is to better understand how these processes go awry and then use that knowledge to identify new treatments.  

    Dr. Sarthy also is a physician at Fred Hutchinson Cancer Center and an assistant professor in the Department of Pediatrics at the University of Washington School of Medicine.

    Board Certification(s)

    Pediatric Hematology-Oncology


    Northwestern University, Chicago, IL
    University of Kansas at Lawrence, Lawrence, KS


    Children's Mercy Hospital, Kansas City, MO


    University of Washington School of Medicine, Seattle, WA

    Clinical Interests

    Hematopoietic stem cell transplantation

    Research Description

    The Sarthy Lab is exploring the epigenetics of pediatric lymphomas to gain insight into how and why these cancers start, in hopes of ultimately finding better treatments. Led by Dr. Jay Sarthy, this work could shed light on why some cancers are resistant to treatment or come back after treatment. The Sarthy Lab is also examining a chemotherapy drug often used in Asia to treat elderly cancer patients to see if it could become a frontline treatment for pediatric cancers. This drug could have fewer side effects than today’s standard treatments.

  • Related Resources

    • The Sarthy Lab

      The Sarthy Lab seeks to improve the lives of children with cancer by studying the fundamental mechanisms cancer cells use to evade therapies and develop resistance. By focusing on chromatin, the mix of proteins and DNA that are found in cells ranging from yeast to fruit flies to humans, we will understand how cancers form and identify safer ways to kill cancer cells while minimizing side effects of these often toxic therapies.

  • Patient Testimonials

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  • Awards and Honors

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  • Publications

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  • Clinical Trials and Research Studies

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