Indi Trehan, MD, MPH
Infectious Disease and Virology, Emergency Medicine
On staff since January 2020
Children's Title: Attending Physician
Academic Title: Associate Professor, Pediatrics; Adjunct Associate Professor, Global Health; Adjunct Associate, Professor of Epidemiology
Research Center: Center for Clinical and Translational Research
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I am driven to improve the health of children in resource-limited settings. As such, my primary clinical interests within Emergency Medicine are in diarrhea, respiratory distress, sepsis, shock, and trauma. I am also very interested in the application of bedside ultrasound to patient care, both in resource-rich and underserved settings. Within Infectious Diseases, my primary clinical interests are in fevers of unknown origin, malaria, neglected tropical diseases, parasitic infections, travel medicine, and tuberculosis.
I have spent roughly half of my medical career working, researching, and teaching in a diverse array of settings around the world. My clinical work abroad includes directing an Ebola Treatment Centre in Sierra Leone, training the first cohort of emergency medicine residents in Haiti, and primary care in a Rohingya refugee camp in Bangladesh, but I am most passionate about training local health care providers in evidence-based, cost-effective care that maximizes survival and human potential. Most recently, I took an academic sabbatical to manage clinical operations in rural Liberia for Partners in Health and then to serve as the Director of Lao Friends Hospital for Children in 2017-2019, where I had the privilege of training the country's largest cohort of pediatricians, pediatric nurses, and pediatric nutritionists, before joining the University of Washington in 2020.
My major academic interests are in the development of a better understanding of the pathophysiology underlying chronic and acute childhood malnutrition, and in improving the diagnosis and treatment of malnourished children. The majority of my research experience in these domains has come in the conduct of large pragmatic clinical trials in rural African villages, as well as in smaller hospital-based cohort studies. I am fortunate to collaborate with colleagues in the Gut Health and Child Survival Scientific Priority Area, within the Global Center for Integrated Health of Women, Adolescents, and Children (Global WACh) in the Department of Global Health.
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Related Pages
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Dr. Indi was the absolute best we could hope for. Compassionate, super intelligent, amazingly fun with kids, so patient with us and all of our questions. He saved our 3 year old son with a rare infection (tularemia!) that nobody else seemed to know about. And he kept following up with us to make sure he was doing well many months later. When all hope was lost, he was there for us — many times over!
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Award Name Award Description Awarded By Award Date Elected member American Pediatric Society 2024 The Nutrition Society Paper of the Month for December 2022 The Nutrition Society 2022 David Fisher Award for Excellence in Safety Nominee (clinical individual) Seattle Children’s Hospital Center for Quality and Patient Safety 2022 David Fisher Award for Excellence in Safety Nominee (clinical group - COVID Monoclonal Antibody Approval Committee) Seattle Children’s Hospital Center for Quality and Patient Safety 2022 Award for Outstanding Faculty Teaching University of Washington Pediatric Residency Program 2021 - 2022 Academic Achievement Award Society for Academic Emergency Medicine Global Emergency Medicine Academy 2019 Society for Pediatric Research Outstanding New Member Society for Pediatric Research 2018 Humanism in Medicine Award Washington University in St. Louis School of Medicine 2016 Gold Humanism Honor Society Faculty Inductee Washington University in St. Louis School of Medicine 2016 Outstanding Commitment to Teaching Award Washington University in St. Louis Pediatrics Residency Program 2015 - 2016 Outstanding Subspecialty Teacher Award Washington University in St. Louis Pediatrics Residency Program 2014 - 2015 Pediatric Clinical Educator Award Washington University in St. Louis Emergency Medicine Residency Program 2013 - 2014 Pediatric Loan Repayment Program Award National Institute of Child Health and Human Development 2010 - 2012 Ruth L. Kirschstein National Research Service Award National Institute of Child Health and Human Development 2009 - 2011 Outstanding Fellow Teaching Award Washington University in St. Louis Pediatrics Residency Program 2007 - 2008 Benzing/Lowe Award for Excellence in Critical Care Cincinnati Children's Hospital Medical Center 2007 Samuel Dalinsky Memorial Award for the Outstanding Graduating Pediatric Resident Cincinnati Children's Hospital Medical Center 2007 Chief Residents’ Award for Commitment to Excellence in Patient Care and Resident Support Cincinnati Children's Hospital Medical Center 2007 Medical Student Research Training Fellowship Howard Hughes Medical Institute 2000 - 2004 Chancellor's Scholarship University of California, Berkeley 1994 - 1998 -
Manuscripts in Refereed Journals
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Ramgopal S, Graves C, Aronson PL, Cruz AT, Rogers A, RIsk Stratification for Hypothermic Infants (RISHI) study groupClinician management practices for infants with hypothermia presenting to the emergency department
Pediatrics, 2023 : 152(6)e2023063000 -
Shannon G, Lauer J, Nacer H, Neilson A, Haj-Hassan T, Shah BK, Jamieson J, Boukari Y, Bornstein S, Mennie N, Vergnano S, Elton L, Shah D, Gram L, Kadir A, Atraqchy Z, Trehan I, et al.A call to action: An open letter from global health professionals
Social Medicine, 2023 : 16(3)152-154 -
Schwartz DJ, Langdon A, Sun X, Langendorf C, Berthé F, Grais RF, Trehan I, Isanaka S, Dantas GRetrospective gut microbiome metagenomic analysis of a randomized placebo-controlled trial of amoxicillin for Nigerien children with severe acute malnutrition
The Lancet Microbe, 2023 : 4(11)e931-e942 -
Hexom BJ, Quao NSA, Bandolin NS, Bonney J, Collier A, Dyal J, Lee JA, Nicholson BD, Rybarczyk MM, Rees CA, Roy CM, Bhaskar N, Kivlehan SM, Global Emergency Medicine Literature Review (GEMLR) GroupGlobal emergency medicine: A scoping review of the literature from 2022
Academic Emergency Medicine, 2023 Oct 9 : in press -
Relan P, Garbern SC, O’Reilly G, Bills CB, Schultz M, Kivlehan S, Trehan I, Becker TKEmergency care interventions for paediatric severe acute respiratory infections in low- and middle- income countries: a systematic review and narrative synthesis
Journal of Global Health, 2023 : 13(-)04065 -
Poonai N, Cohen DM, MacDowell D, Mistry RD, Mintegi S, Craig S, Roland D, Miller M, Shavit M, Paediatric Emergency Research Netweorks (PERN) PAINT Study GroupSedation and analgesia for reduction of pediatric ileocolic intussusception (PAINT)
JAMA Network Open, 2023 : 6(6)e2317200 -
Odei Obeng-Amoako GA, Stobaugh H, Wrottesley SV, Khara T, Binns P, Trehan I, Black RE, Webb P, Mwangome M, Bailey J, Bahwere P, Dolan C, Boyd E, Briend A, Myatt MA, Lelijveld NHow do children with severe underweight and wasting respond to treatment? A pooled secondary data analysis to inform future intervention studies
Maternal & Child Nutrition, 2023 : 19(1)e13434 -
Woeltje MM, Evanoff AB, Helmink BA, Culbertson DL, Maleta KM, Manary MJ, Trehan ICommunity-based management of acute malnutrition for infants under 6 months of age is safe and effective: Analysis of operational data
Public Health Nutrition, 2023 : 26(1)246-255 -
Vora SB, Englund JA, Trehan I, Waghmare A, Kong A, Adler A, Zerr DMMonoclonal antibody and antiviral therapy for early treatment of mild- to-moderate COVID-19 in high-risk children and adolescents
The Pediatric Infectious Disease Journal, 2023 : 42(1)32-34 -
Garbern SC, Relan P, O’Reilly GM, Bills CB, Schultz ML, Trehan I, Kivlehan SM, Becker TKA systematic review of acute and emergency care interventions for adolescents and adults with severe acute respiratory infections including COVID-19 in low- and middle-income countries
Journal of Global Health, 2022 : 12(-)05039 -
Kivlehan SM, Hexom BJ, Bonney J, Collier A, Nicholson BD, Quao NSA, Rybarczyk MM, Selvam A, Rees CA, Roy CM, Bhaskar N, Becker TK, Global Emergency Medicine Literature Review (GEMLR) GroupGlobal emergency medicine: A scoping review of the literature from 2021
Academic Emergency Medicine, 2022 : 29(10)1264-1274 -
Noori N, Skrip LA, Oron AP, McCarthy KA, Proctor JL, Chabot-Couture G, Althouse BM, Phelan KPQ, Trehan IPotential impacts of mass nutritional supplementation on measles dynamics: a simulation study
The American Journal of Tropical Medicine and Hygiene, 2022 : 107(4)863-872 -
King S, D'Mello-Guyett L, Yakowenko E, Riems B, Gallandat K, Chabi SM, Mohamud FA, Ayoub K, Olad AH, Aliou B, Marshak A, Trehan I, Cumming O, Stobaugh HA multi-country, prospective cohort study to measure rate and risk of relapse among children recovered from severe acute malnutrition in Mali, Somalia, and South Sudan: A study protocol
BMC Nutrition, 2022 : 8(-)90 -
Tunҫ EM, Koid Jia Shin C, Usoro E, Thomas-Smith SE, Trehan I, Migita RT, Keilman AEPediatric croup during the coronavirus disease 2019 Omicron variant surge
The Journal of Pediatrics, 2022 : 247(8)147-149 -
Engl M, Binns P, Trehan I, Lelijveld N, Angood C, McGrath M, Groce N, Kerac MChildren living with disabilities are neglected from severe malnutrition protocols: A guideline review
Archives of Disease in Childhood, 2022 : 107(7)637-643 -
Park BL, Trehan IAmoxicillin dose and duration of treatment on the need for antibiotic re-treatment in children with community-acquired pneumonia
JAMA, 2022 : 327(11)1089-1090 -
Basu S, Copana R, Morales Jr R, Anugulruengkitt S, Puthanakit T, Maramba-Lazarte C, Williams P, Musembi J, Boga M, Issack M, Hokororo A, Falade AG, Trehan I, Molyneux E, Arscott-Mills T, Alemayehu T, Bryant PAKeeping it real: Antibiotic use problems and stewardship solutions in low- and middle-income countries
The Pediatric Infectious Disease Journal, 2022 : 41(3S)S18-S25 -
Trehan I, Kivlehan SM, Balhara KS, Bonney J, Hexom BJ, Pousson AY, Quao NSA, Rybarczyk MM, Selvam A, Nicholson BD, Bhaskar N, Becker TK, on behalf of the Global Emergency Medicine Literature Review (GEMLR) GroupGlobal emergency medicine: A scoping review of the literature from 2020
Academic Emergency Medicine, 2021 : 28(11)1328-1340 -
Winders WT, Gabern S, Bills C, Relan P, Schultz M, Kivlehan S, Trehan I, Becker TK, McQuillan RThe effects of mobile health on emergency care in low- and middle-income countries: A systematic review and narrative synthesis
Journal of Global Health, 2021 : 11(1)04023 -
Angood C, Kerac M, Black R, Briend A, Hanson K, Jarrett S, Manary M, McGrath M, Zagre N, Lelijveld N, Mayberry A, CHNRI Collaborators, Council of Reseach & Technical Advice on Acute Malnutrition (CORTASAM)Treatment of child wasting: Results of a child health and nutrition research initiative (CHNRI) prioritization exercise
F1000Research, 2021 : 10(-)126 -
Winders WT, Bustamante ND, Gabern SC, Bills C, Coker A, Trehan I, Osei-Ampofo M, Levine AC, on behalf of the Global Emergency Medicine Literature Review (GEMLR) GroupEstablishing the effectiveness of interventions provided to first responders to prevent and/or treat mental health effects of response to a disaster: A systematic review
Disaster Medicine and Public Health Preparedness, 2021 : 15(1)115-126 -
Trehan I, Kivlehan SM, Balhara KS, Hexom BJ, Pousson AY, Quao NSA, Rybarczyk MM, Selvam A, Bonney J, Bhaskar N, Becker TK, and on behalf of the Global Emergency Medicine Literature Review (GEMLR) GroupGlobal emergency medicine: A review of the literature from 2019
Academic Emergency Medicine, 2021 : 28(1)117-128 -
D’Souza AW, Moodley-Govender E, Berla B, Kelkar T, Wang B,Sun X, Daniels B, Coutsoudis A, Trehan I, Dantas GCotrimoxazole prophylaxis increases resistance gene prevalence and α-diversity but decreases ß-diversity in the gut microbiome of HIV-exposed, uninfected infants
Clinical Infectious Diseases, 2020 : 71(11)2858-2868 -
Trehan IThe past informs the future: inpatient mortality in severe childhood malnutrition
The American Journal of Clinical Nutrition, 2020 : 112(4)911-912 -
Collins EM, Iroh Tam PY, Trehan I, Cartledge P, Bose A, Lanaspa M, Kidd P, Bassat QStrengthening health systems and improving the capacity of pediatric care centers to respond to epidemics such as COVID-19 in resource-limited settings
Journal of Tropical Pediatrics, 2020 : 66(4)357-365 -
Trehan I, Mouayaxeng S, Nigogosyan MAAxillary calcification due to Bacillus Calmette-Guérin vaccination
The Journal of Pediatrics, 2020 : 222(2)218-219 -
Trehan IAnthropometry’s promise and pitfalls in the diagnosis of undernutrition among infants
Archives of Disease in Childhood, 2020 : 105(6)522-523 -
Elenga N, Nacher M, Trehan IThe imperative of dengue vaccination for children with sickle cell disease
Journal of Tropical Pediatrics, 2020 : 66(3)245-247 -
Suchdev PS, Trehan IOptimizing iron supplementation for children with severe malaria
The American Journal of Clinical Nutrition, 2020 : 111(5)939-940 -
Ordiz MI, Janssen S, Humphrey G, Ackermann G, Stephenson K, Agapova S, Divala O, Kaimila Y, Maleta K, Zhong C, Knight R, Trehan I, Tarr PI, Rusconi B, Manary MJThe effect of legume supplementation on the gut microbiota in rural Malawian infants aged 6 to 12 months
The American Journal of Clinical Nutrition, 2020 : 111(4)884-892 -
Hess SY, Smith TJ, Fischer PR, Trehan I, Hiffler L, Arnold CD, Sitthideth D, Tancredi DJ, Schick MA, Yeh J, Stein-Wexler R, McBeth CN, Tan X, Nhiacha K, Kounnavong SEstablishing a case definition of thiamine responsive disorders (TRD) among infants in Lao PDR: protocol for a prospective cohort study
BMJ Open, 2020 : 10(2)e036539 -
Frison S, Angood C, Khara T, Bahwere P, Black RE, Briend A, Connell N, Fenn B, Isanaka S, James P, Kerac M, Mayberry A, Myatt M, Dolan C, wasting prevention Working Group CollaboratorsPrevention of child wasting: Results of a Child Health & Nutrition Research Initiative (CHNRI) prioritisation exercise
PLoS ONE, 2020 : 15(2)e0228151 -
Schulze KV, Swaminathan S, Howell S, Jajoo A, Lie NC, Brown O, Sadat R, Hall N, Zhao L, Marshall K, May T, Reid ME, Taylor-Bryan C, Wang X, Belmont JW, Guan Y, Manary MJ, Trehan I, McKenzie CA, Hanchard NAEdematous severe acute malnutrition is characterized by hypomethylation of DNA
Nature Communications, 2019 : 105791 -
Natarajan DK, Homthavong P, Trehan ISmall bowel obstruction secondary to wild banana seed ingestion
The American Journal of Tropical Medicine and Hygiene, 2019 : 101(6)1195-1196 -
Trehan I, Osei-Ampofo M, Balhara KS, Hexom BJ, Kivlehan SM, Modi P, Pousson AY, Selvam A, Quao NSA, Cho DK, Becker TK, Levine AC, and on behalf of the Global Emergency Medicine Literature Review (GEMLR) GroupGlobal emergency medicine: a review of the literature from 2018
Academic Emergency Medicine, 2019 : 26(10)1186-1196 -
Trehan I, Grabowsky M, Schenker IOral rehydration therapy and zinc: looking back and looking ahead
Journal of Tropical Pediatrics, 2019 : 65(5)417-420 -
Woeltje MM, Newland JG, Trehan IWorld Health Organization treatment recommendations for nonsevere fast-breathing pneumonia need to be updated
JAMA Pediatrics, 2019 : 173(6)607-608 -
Palmer ES, Saysamoneyeu P, Siu JM, Thammaseng A, Trehan IDown boy! A case of acute abdomen following a dog bite to the scrotum
BMC Pediatrics, 2019 : 19169 -
Balhara K, Bustamante N, Selvam A, Winders W, Coker A, Trehan I, Becker T, Levine ABystander assistance for trauma victims in low- and middle-income countries: a systematic review of prevalence and training interventions
Prehospital Emergency Care, 2019 : 23(3)389-410 -
Kaimila Y, Pitman RT, Divala O, Hendrixson DT, Stephenson KB, Agapova S, Trehan I, Maleta K, Manary MJDevelopment of acute malnutrition despite nutritional supplementation in Malawi
Journal of Pediatric Gastroenterology and Nutrition, 2019 : 68(5)734-737 -
Cheng WD, Wold KJ, Bollinger LB, Ordiz MI, Shulman RJ, Maleta KM, Manary MJ, Trehan ISupplementation with lactoferrin and lysozyme ameliorates environmental enteric dysfunction: a double-blind, randomized, placebo-controlled trial
The American Journal of Gastroenterology, 2019 : 114(4)671-678 -
Berna AZ, Schaber CL, Bollinger LB, Mwale M, Mlotha-Mitole R, Trehan I, Odom John ARComparison of breath sampling methods: a post hoc analysis from observational cohort studies
Analyst, 2019 : 144(6)2026-2033 -
Kaimila Y, Davila O, Agapova SE, Stephenson KB, Thakwalakwa C, Trehan I, Manary MJ, Maleta KMConsumption of animal-source protein is associated with improved height-for-age z scores in rural Malawian children aged 12-36 months
Nutrients, 2019 : 11(2)480 -
Sultan M, Mengitsu G, Debebe F, Azazh A, Trehan IThe burden on emergency centres to provide care for critically ill patients in Addis Ababa, Ethiopia
African Journal of Emergency Medicine, 2018 : 8(4)150-154 -
Becker TK, Trehan I, Hayward AS, Hexom BJ, Kivlehan S, Lunney KM, Modi P, Osei-Ampofo M, Pousson A, Cho DK, Levine AC, and on behalf of the Global Emergency Medicine Literature Review (GEMLR) GroupGlobal emergency medicine: a review of the literature from 2017
Academic Emergency Medicine, 2018 : 25(11)1287-1298 -
Bassat Q, Bose A, Cartledge P, Collins EM, Jullien S, Lanaspa M, Simkiss D, Trehan ICommitment to publication quality and integrity: a message from the journal’s editorial board
Journal of Tropical Pediatrics, 2018 : 64(5)355-359 -
Ngoma TN, Chimimba UK, Mwangwela AM, Thakwalakwa C, Maleta KM, Manary MJ, Trehan IEffect of cowpea flour processing on the chemical properties and acceptability of a novel cowpea blended maize porridge
PLoS ONE, 2018 : 13(7)e0200418 -
Stobaugh HC, Rogers BL, Rosenberg IH, Webb P, Maleta KM, Manary MJ, Trehan IChildren with poor linear growth are at risk for repeated relapse to wasting after recovery from moderate acute malnutrition
The Journal of Nutrition, 2018 : 148(6)974-979 -
Trehan I, Bassat QThe unbearable lightness of being malnourished: severe acute malnutrition remains a neglected tropical disease
Journal of Tropical Pediatrics, 2018 : 64(3)169-173 -
Schaber C, Katta N, Bollinger LB, Mwale M, Mlotha-Mitole R, Trehan I, Raman B, Odom John ARBreathprinting reveals malaria-associated biomarkers and mosquito attractants
The Journal of Infectious Diseases, 2018 : 217(10)1553-1560 -
Stobaugh HC, Rogers BL, Webb P, Rosenberg IH, Thakwalaka C, Maleta KM, Trehan I, Manary MHousehold-level factors associated with relapse following discharge from treatment for moderate acute malnutrition
British Journal of Nutrition, 2018 : 119(9)1039-1046 -
Trehan I, De Silva SCManagement of Ebola virus disease in children
Infectious Disease Clinics of North America, 2018 : 32(1)201-214 -
Trehan IRotavirus vaccines: a social injustice story
Journal of Tropical Pediatrics, 2018 : 64(1)1-3 -
Agapova SE, Stephenson KB, Divala O, Kaimila Y, Maleta KM, Thakwalakwa C, Ordiz MI, Trehan I, Manary MJAdditional common bean in the diet of Malawian children does not affect linear growth, but reduces intestinal permeability
The Journal of Nutrition, 2018 : 148(2)267-274 -
Semba RD, Trehan I, Li X, Salem Jr. N, Moaddel R, Ordiz MI, Maleta KM, Kraemer K, Manary MJLow serum ω-3 and ω-6 polyunsaturated fatty acids and other metabolites are associated with poor linear growth in young children from rural Malawi
The American Journal of Clinical Nutrition, 2017 : 106(6)1490-1499 -
Stephenson KB, Agapova SE, Divala O, Kaimila Y, Maleta KM, Thakwalakwa C, Ordiz MI, Trehan I, Manary MJComplementary feeding with cowpea reduces growth faltering in rural Malawian infants: a blind, randomized controlled clinical trial
The American Journal of Clinical Nutrition, 2017 : 106(6)1500-1507 -
Le Doare K, O’Driscoll M, Turner K, Seedat F, Russell NJ, Seale AC, Heath PT, Lawn JE, Baker CJ, Bartlett L, Cutland C, Gravett MG, Ip M, Madhi SA, Rubens CE, Saha SK, Schrag S, Sobanjo-ter Meulen A, Vekemans J, Kampmann B, for the GBS Intrapartum Antibiotic Investigator GroupIntrapartum antibiotic chemoprophylaxis policies for the prevention of Group B Streptococcal disease worldwide: systematic review
Clinical Infections Diseases, 2017 : 65(S2)S143-S151 -
Cheng WD, Wold KJ, Benzoni NS, Thakwalakwa C, Maleta KM, Manary MJ, Trehan ILactoferrin and lysozyme to reduce environmental enteric dysfunction and stunting in Malawian children: study protocol for a randomized controlled trial
Trials, 2017 : 18523 -
Borresen EC, Zhang L, Trehan I, Nealon NJ, Maleta KM, Manary MJ, Ryan EPThe nutrient and metabolite profile of three complementary legume foods with potential to improve gut health in rural Malawian children
Current Developments in Nutrition, 2017 : 1(10)e001610 -
Callaghan-Gillespie M, Schaffner AA, Garcia P, Fry J, Eckert R, Malek S, Trehan I, Thakwalakwa C, Maleta KM, Manary MJ, Papathakis PCTrial of ready to use supplemental food and corn soy blend in pregnant Malawian women with moderate malnutrition: a randomized, controlled clinical trial
The American Journal of Clinical Nutrition, 2017 : 106(4)1062-1069 -
Bhutta ZA, Berkley JA, Bandsma RHJ, Kerac M, Trehan I, Briend ASevere childhood malnutrition
Nature Reviews Disease Primers, 2017 : 317067 -
Becker TK, Hansoti B, Bartels S, Hayward A, Hexon B, Lunney K, Marsh R, Osei-Ampofo M, Trehan I, Chang J, Levine AC, and on behalf of the Global Emergency Medicine Literature Review (GEMLR) GroupGlobal emergency medicine: a review of the literature from 2016
Academic Emergency Medicine, 2017 : 24(9)1150-1160 -
Stobaugh HC, Bollinger LB, Adams SE, Crocker AH, Grise JB, Kennedy JA, Thakwalakwa C, Maleta KM, Dietzen DJ, Manary MJ, Trehan IEffect of a package of health and nutrition services on sustained recovery in children after moderate acute malnutrition and factors related to sustaining recovery: a cluster randomized trial
The American Journal of Clinical Nutrition, 2017 : 106(2)657-666 -
Heikens GT, Manary MJ, Trehan IAfrican children with severe pneumonia remain at high risk for death even after discharge
Paediatric and Perinatal Epidemiology, 2017 : 31(3)243-244 -
Semba RD, Gonzalez-Freire M, Moaddel R, Trehan I, Maleta KM, Khadeer M, Ordiz MI, Ferrucci L, Manary MJEnvironmental enteric dysfunction is associated with altered bile acid metabolism
Journal of Pediatric Gastroenterology and Nutrition, 2017 : 64(4)536-540 -
Semba RD, Trehan I, Li X, Moaddel R, Ordiz MI, Maleta KM, Kraemer K, Shardell M, Ferrucci L, Manary MEnvironmental enteric dysfunction is associated with carnitine deficiency and altered fatty acid oxidation
EBioMedicine, 2017 : 1757-66 -
Ordiz MI, Stephenson K, Agapova S, Wylie KM, Maleta K, Martin J, Trehan I, Tarr PI, Manary MJEnvironmental enteric dysfunction and the fecal microbiota in Malawian children
The American Journal of Tropical Medicine and Hygiene, 2017 : 96(2)473-476 -
Wang AZ, Shulman RJ, Crocker AH, Thakwalakwa C, Maleta KM, Devaraj S, Manary MJ, Trehan IA combined package of zinc, multiple micronutrients, and albendazole does not ameliorate environmental enteric dysfunction or stunting in rural Malawian children in a double-blind, randomized, controlled trial
The Journal of Nutrition, 2017 : 147(1)97-103 -
Di Giovanni V, Bourdon C, Wang DX, Seshadri S, Senga E, Versloot CJ, Voskuijl W, Semba RD, Trehan I, Moaddel R, Ordiz MI, Zhang L, Parkinson J, Manary MJ, Bandsma RHMetabolomic changes in serum of children with different clinical diagnoses of malnutrition
The Journal of Nutrition, 2016 : 146(12)2436-2444 -
Ordiz MI, Shaikh N, Trehan I, Maleta K, Stauber J, Shulman R, Devaraj S, Tarr PI, Manary MJEnvironmental enteric dysfunction is associated with poor linear growth and can be identified by host fecal mRNAs
Journal of Pediatric Gastroenterology and Nutrition, 2016 : 63(5)453-459 -
Becker TK, Hansoti B, Bartels S, Bisanzo M, Jacquet GA, Lunney K, Marsh R, Osei-Ampofo M, Trehan I, Lam C, Levine AC, and on behalf of the Global Emergency Medicine Literature Review (GEMLR) GroupGlobal emergency medicine: a review of the literature from 2015
Academic Emergency Medicine, 2016 : 23(10)1183-1191 -
Bollinger LB, Trehan IA courageous report on the management of malnutrition
Nutrients, 2016 : 8(10)603 -
Trehan I, Goldbach HS, LaGrone LN, Meuli GJ, Wang RJ, Maleta KM, Manary MJAntibiotics as part of the management of severe acute malnutrition
Malawi Medical Journal, 2016 : 28(3)123-130 -
Semba RD, Trehan I, Freire-Gonzalez M, Kraemer K, Moaddel R, Ordiz MI, Ferrucci L, Manary MJPerspective: the potential role of essential amino acids and the mechanistic target of rapamycin complex 1 (mTORC1) pathway in the pathogenesis of child stunting
Advances in Nutrition, 2016 : 7(5)853-865 -
Trehan I, Kelly P, Shaikh N, Manary MJNew insights into environmental enteric dysfunction
Archives of Disease in Childhood, 2016 : 101(8)741-744 -
Trehan I, Schechtman KB, Manary MJAmoxicillin for severe acute malnutrition in children
The New England Journal of Medicine, 2016 : 375(2)191 -
Trehan I, Manary MJAn important chapter in the infection-malnutrition story
The Lancet Global Health, 2016 : 4e430-e431 -
Semba RD, Zhang P, Gonzalez-Freire M, Moaddel R, Trehan I, Maleta KM, Ordiz MI, Ferrucci L, Manary MJThe association of serum choline with linear growth failure in young children from rural Malawi
The American Journal of Clinical Nutrition, 2016 : 104(7)191-197 -
Semba RD, Shardell M, Trehan I, Moaddel R, Maleta KM, Ordiz MI, Kraemer K, Khadeer M, Ferrucci L, Manary MJMetabolic alterations in children with environmental enteric dysfunction
Scientific Reports, 2016 : 628009 -
Semba RD, Shardell M, Ashour FA, Moaddel R, Trehan I, Maleta KM, Ordiz MI, Kraemer K, Khadeer MA, Ferrucci L, Manary MJChild stunting is associated with low circulating essential amino acids
EBioMedicine, 2016 : 6246-252 -
Stobaugh HS, Ryan KN, Kennedy JA, Grise JB, Crocker AH, Thakwalakwa C, Litkowski PE, Maleta KM, Manary MJ, Trehan IIncluding whey protein and whey permeate in ready-to-use supplementary food improves recovery rates in children with moderate acute malnutrition: A randomized double-blinded clinical trial
The American Journal of Clinical Nutrition, 2016 : 103(3)926-933 -
Trehan I, Kelly T, Marsh RH, George PM, Callahan CWMoving towards a more aggressive and comprehensive model of care for children with Ebola virus disease
The Journal of Pediatrics, 2016 : 170(1)28-33.e7 -
Glaser E, Davis S, Flomo C, Sliney A, Tiah MW, Barron K, Balarabe AD, Bearse E, Brilliant B, Brownie S, Chapman S, Conteh S, Churchill R, Cunningham S, Daost P, Downes EA, English CR, Ferranti EP, Foster J, Galante ME, Garland J, Germain M, Ghahreman A, Gimbel S, Goldman D, Haileyesus MD, Hall A, Hall E, Hann K, Headrick E, Hickox K, Huster K, Jones EA, Kalal M, Kaonga NN, Kardas-Nelson M, Kloepper D, Lee J, Leffers J, McDermott-Levy R, Maher MD, Matarrese P, Mead A, Michaels A, Mondaye HNS, Nyuma SJ, Phillips J, Pohl JM, Reilly CM, Rodriguez J, Rollosson M, Sarchet N, Schicker RS, Schlough GW, Sliney A, Sonenberg A, Spray K, Subah MK, Sullivan B, Traisci-Marandola D, Trehan I, Wolf KAThe Harvard-LSHTM panel on the global response to Ebola report
The Lancet, 2016 : 387(10021)848 -
Blanton LV, Charbonneau MR, Salih T, Barratt MJ, Venkatesh S, Ilkaveya O, Subramanian S, Manary MJ, Trehan I, Jorgensen JM, Fan Y, Henrissat B, Leyn SA, Rodionov DA, Osterman AL, Maleta KM, Newgard CB, Ashorn P, Dewey KG, Gordon JIGut bacteria that rescue growth impairments transmitted by microbiota from undernourished children
Science, 2016 : 351(6275)aad3311 -
Yu J, Ordiz MI, Stauber J, Shaikh N, Trehan I, Barnell E, Head RD, Maleta K, Tarr PI, Manary MJEnvironmental enteric dysfunction includes a broad spectrum of inflammatory responses and epithelial repair processes
Cellular and Molecular Gastroenterology and Hepatology, 2016 : 2(2)158-174.e1 -
Trehan I, Benzoni NS, Wang AZ, Bollinger LB, Ngoma TN, Chimimba UK, Stephenson KB, Agapova SE, Maleta KM, Manary MJCommon beans and cowpeas as complementary foods to reduce environmental enteric dysfunction and stunting in Malawian children: protocol for two randomized controlled trials
Trials, 2015 : 16(1)520 -
Reyes A, Blanton LV, Cao S, Zhao G, Manary M, Trehan I, Smith MI, Wang D, Virgin HW, Rohwer F, Gordon JIGut DNA viromes of Malawian twins discordant for severe acute malnutrition
Proceedings of the National Academy of Sciences of the United States of America, 2015 : 112(38)11941-11946 -
Horst JA, Trehan I, Warner BW, Cohn BGCan children with uncomplicated acute appendicitis be treated with antibiotics instead of an appendectomy?
Annals of Emergency Medicine, 2015 : 66(2)119-122 -
Becker TK, Bartels S, Hansoti B, Jacquet GA, Lunney K, Marsh R, Osei-Ampofo M, Lam C, Levine AC, and on behalf of the Global Emergency Medicine Literature Review (GEMLR) GroupGlobal emergency medicine: a review of the literature from 2014
Academic Emergency Medicine, 2015 : 22(8)976-984 -
Hsieh JC, Liu L, Zeilani M, Ickes S, Trehan I, Maleta K, Craig C, Thakwalakwa C, Singh L, Brenna JT, Manary MJHigh oleic ready-to-use therapeutic food maintains docosaheaenoic acid status in severe malnutrition: a randomized, blinded trial
Journal of Pediatric Gastroenterology and Nutrition, 2015 : 61(1)138-143 -
Brenna JT, Akomo P, Bahwere P, Berkley JA, Calder PC, Jones KD, Liu L, Manary M, Trehan I, Briend ABalancing omega-6 and omega-3 fatty acids in ready-to-use therapeutic foods (RUTF)
BMC Medicine, 2015 : 13117 -
Angood C, McGrath M, Mehta S, Mwangome M, Lung'aho M, Roberfroid D, Perry A, Wilkinson C, Israel A-D, Bizoueme C, Haider R, Seal A, Berkley J, Kerac M, MAMI Working GroupResearch priorities to improve the management of acute malnutrition in infants aged <6 months (MAMI)
PLOS Medicine, 2015 : 12(4)e1001812 -
Iannotti LL, Trehan I, Clitheroe KL, Manary MJDiagnosis and treatment of severely malnourished children with diarrhoea
Journal of Paediatrics and Child Health, 2015 : 51(4)387-395 -
Trehan I, Banerjee S. Murray E, Ryan KN, Thakwalakwa C, Maleta KM, Manary MJExtending supplementary feeding for children under five with moderate acute malnutrition leads to lower relapse rates
Journal of Pediatric Gastroenterology and Nutrition, 2015 : 60(4)544-549 -
Trehan I, Manary MJManagement of severe acute malnutrition in low-income and middle-income countries
Archives of Disease in Childhood, 2015 : 100(3)283-287 -
Kau AL, Planer JD, Liu J, Rao S, Yatsunenko T, Trehan I, Manary MJ, Liu T-C, Stappenbeck TS, Maleta KM, Ashorn P, Dewey KG, Houpt ER, Hsieh CS, Gordon JIFunctional characterization of IgA-targeted bacterial taxa from malnourished Malawian children that produce diet-dependent enteropathy
Science Translational Medicine, 2015 : 7(276)276ra24 -
Smith HE, Ryan KN, Stephenson KB, Westcott C, Thakwalakwa C, Maleta K, Cheng JY, Brenna JT, Shulman RJ, Trehan I, Manary MJMultiple micronutrient supplementation transiently ameliorates environmental enteropathy in Malawian children aged 12–35 months in a randomized controlled clinical trial
The Journal of Nutrition, 2014 : 144(12)2059-2065 -
Ryan KN, Stephenson KB, Trehan I, Shulman RJ, Thakwalakwa C, Murray E, Maleta K, Manary MZinc or albendazole attenuates the progression of environmental enteropathy: a randomized controlled trial
Clinical Gastroenterology and Hepatology, 2014 : 12(9)1507-1513 -
Becker TK, Jacquet GA, Marsh R, Schroeder ED, Foran M, Bartels S, Duber HC, Cockrell H, Levine AC, and on behalf of the Global Emergency Medicine Literature Review (GEMLR) GroupGlobal emergency medicine: a review of the literature from 2013
Academic Emergency Medicine, 2014 : 21(7)810-817 -
Gough EK, Moodie EEM, Prendergast AJ, Johnson SMA, Humphrey JH, Stoltzfus RJ, Walker AS, Trehan I, Gibb DM, Goto R, Tahan S, de Morais MB, Manges ARThe impact of antibiotics on growth in children in low and middle-income countries: a systematic review and meta-analysis of randomised controlled trials
BMJ, 2014 : 348g2267 -
Iannotti LL, Trehan I, Manary MJReview of the safety and efficacy of vitamin A supplementation in the treatment of children with severe acute malnutrition
Nutrition Journal, 2013 : 12125 -
Trehan I, Maleta KM, Manary MJAntibiotics for uncomplicated severe malnutrition
The New England Journal of Medicine, 2013 : 368(25)2436-2437 -
Wang RJ, Trehan I, LaGrone LN, Weisz AJ, Thakwalakwa CM, Maleta KM, Manary MJInvestigation of food acceptability and feeding practices for lipid nutrient supplements and blended flours used to treat moderate malnutrition
Journal of Nutrition Education and Behavior, 2013 : 45(3)258-263 -
Chang CY, Trehan I, Wang RJ, Thakwalakwa C, Maleta K, Deitchler M, Manary MJChildren successfully treated for moderate acute malnutrition remain at risk for malnutrition and death in the subsequent year after recovery
The Journal of Nutrition, 2013 : 143(2)215-220 -
Smith MI, Yatsunenko T, Manary MJ, Trehan I, Mkakosya R, Cheng J, Kau AL, Rich SS, Concannon P, Mychaleckyj JC, Liu J, Houpt E, Li JV, Holmes E, Nicholson J, Knights D, Ursell LK, Knight R, Gordon JIGut microbiomes of Malawian twin pairs discordant for kwashiorkor
Science, 2013 : 339(6119)548-554 -
Trehan I, Goldbach HS, LaGrone LN, Meuli GJ, Wang RJ, Maleta KM, Manary MJAntibiotics as part of the management of severe acute malnutrition
The New England Journal of Medicine, 2013 : 368(5)425-435 -
Yatsunenko T, Rey FE, Manary MJ, Trehan I, Dominguez-Bello MG, Contreras M, Magris M, Hidalgo G, Baldassano RN, Anokhin AP, Heath AC, Warner B, Reeder J, Kuczynski J, Caporaso JG, Lozupone CA, Lauber C, Clemente JC, Knights D, Knight R, Gordon JIHuman gut microbiome viewed across age and geography
Nature, 2012 : 486(7402)222-227 -
Trehan I, O’Hare BA, Phiri A, Heikens GTChallenges in the management of HIV-infected malnourished children in sub-Saharan Africa
AIDS Research and Treatment, 2012 : 2012790786 -
LaGrone LN, Trehan I, Meuli GJ, Wang RJ, Thakwalakwa C, Maleta K, Manary MJA novel fortified blended flour, CSB++, is not inferior to lipid-based ready-to-use supplementary foods for the treatment of moderate acute malnutrition in Malawian children
The American Journal of Clinical Nutrition, 2012 : 95(1)212-219 -
Weisz A, Meuli G, Thakwalakwa C, Trehan I, Maleta K, Manary MThe duration of diarrhea and fever are associated with growth faltering in rural Malawian children aged 6-18 months
Nutrition Journal, 2011 : 1025 -
Stadler LP, Donauer S, Rice M, Trehan I, Salisbury S, Staat MAFactors associated with protective antibody levels to vaccine preventable diseases in internationally adopted children
Vaccine, 2010 : 29(1)95-103 -
Oakley E, Reinking J, Sandige H, Trehan I, Kennedy G, Maleta K, Manary MA ready-to-use therapeutic food with 10% milk content is less effective than one with 25% milk content in the treatment of severely malnourished children
The Journal of Nutrition, 2010 : 140(12)2248-2252 -
Staat MA, Stadler LP, Donauer S, Trehan I, Rice M, Salisbury SSerologic testing to verify the immune status of internationally adopted children against vaccine preventable diseases
Vaccine, 2010 : 28(50)7947-7955 -
Trehan I, Amthor RE, Maleta K, Manary MJEvaluation of the routine use of amoxicillin as part of the home-based treatment of severe acute malnutrition
Tropical Medicine & International Health, 2010 : 15(9)1022-1028 -
Trehan I, Meuli GJMango contact allergy
Journal of Travel Medicine, 2010 : 17(4)284 -
Trehan I, Shulman RJ, Ou CN, Maleta K, Manary MJA randomized, double-blind, placebo-controlled trial of rifaximin, a non-absorbable antibiotic, in the treatment of tropical enteropathy
The American Journal of Gastroenterology, 2009 : 104(9)2326-2333 -
Trehan I, Fritz SAGroup B Streptococcus vertebral osteomyelitis-discitis in an immunocompetent adolescent
The Pediatric Infectious Disease Journal, 2009 : 28(6)552-553 -
Trehan I, Turpin BKNeonatal respiratory distress due to bilateral dacrocystoceles
The Journal of Pediatrics, 2008 : 153(3)438 -
Trehan I, Meinzen-Derr JK, Jamison L, Staat MATuberculosis screening in internationally adopted children: the need for initial and repeat testing
Pediatrics, 2008 : 122(1)e7-e14 -
Trehan I, Piskur JR, Prystowsky JJCollaboration between medical students and NGOs: a new model in international health education
Medical Education, 2003 : 37(11)1031 -
Trehan I, Morandi F, Blaszczak LC, Shoichet BKUsing steric hindrance to design new inhibitors of class C β-lactamases
Chemistry & Biology, 2002 : 9(9)971-980 -
Beadle BM, Trehan I, Focia PJ, Shoichet BKStructural milestones in the reaction pathway of an amide hydrolase: substrate, acyl, and product complexes of cephalothin with AmpC β-lactamase
Structure, 2002 : 10(3)413-424 -
Trehan I, Beadle BM, Shoichet BKInhibition of AmpC β-lactamase through a destabilizing interaction in the active site
Biochemistry, 2001 : 40(27)7992-7999
Book Chapters
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Manary MJ, Trehan ISevere Malnutrition
Goldman-Cecil Medicine 27th edition, 2024 -
Trehan IInfectious Diseases I
Pediatric Emergency Medicine Question Review Book 2023, 2023 -
Trehan IScarlet Fever
Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020 -
Trehan IAcute Rheumatic Fever
Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020 -
Trehan IPeriorbital Cellulitis
Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020 -
Spectorsky KA, Trehan IHIV/AIDS
Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020 -
Trehan IHerpes Simplex
Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020 -
Trehan ICroup
Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020 -
Trehan IConjunctivitis, Neonatal
Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020 -
Trehan ICat Scratch Disease
Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020 -
Trehan IArthritis, Septic
Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020 -
Manary MJ, Trehan IProtein-Energy Malnutrition
Goldman-Cecil Medicine 26th edition, 2019 -
Trehan I, George PM, Callahan CWComprehensive Clinical Care for Children with Ebola
Pregnant in the Time of Ebola: Women and Their Children in the 2013-2015 West African Epidemic, 2019 -
Trehan I, Manary MJChildhood Undernutrition in Resource-Limited Settings
Rudolph’s Pediatrics 23rd edition, 2018 -
Ryan E, Trehan I, Smith K, Manary MDietary Health Benefits, Phytochemicals and Anti-Nutritional Factors in Grain Legumes
Achieving Sustainable Cultivation of Grain Legumes, 2018 -
Manary MJ, Trehan IProtein-Energy Malnutrition
Goldman-Cecil Medicine 25th edition, 2015
Manuscripts Submitted
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Smith T, Arnold CD, Fischer PR, Trehan I, Hiffler L, Sitthideth D, Stein-Wexler R, Yeh J, Jones KS, Hampel D, Tancredi DJ, Schick MA, McBeth CN, Tan X, Allen LH, Syasone S, Kounnavong S, Hess SYA predictive model for thiamine responsive disorders among infants and young children: results from a prospective cohort study in Lao PDR
2023 Nov 17 -
King S, Marshak A, D’Mello-Guyett L, Yakowenko E, Chabi SM, Samake S, Bunkembo M, Diarra S, Mohamud FA, Omar MS, Lamwaka NG, Gose M, Ayoub K, Olad AH, Aliou B, Trehan I, Cumming O, Stobaugh HRates and risk factors for relapse among children recovered from severe acute malnutrition: Results from a multi-country, prospective controlled cohort study in Mali, South Sudan, and Somalia
2023 Oct 13 -
Tickell KD, Tiwari R, Yoshioka E, Otieno J, Shah A, Richardson BA, Keter L, Anyango M, Nyabinda C, Trehan I, McGrath CJ, Means AR, Houpt E, Liu J, Platts-Mills J, Njunge JM, Rwigi D, Diakhate MM, Nyaoke J, Ochola E, John-Stewart GC, Walson JL, Pavlinac PB, Singa BOLactoferrin and lysozyme to promote nutritional, clinical, and enteric recovery: A protocol for a factorial, blinded, placebo-controlled randomized trial among children with diarrhea and malnutrition (the Boresha Afya trial)
2023 Aug 31
Other Publications
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Hendrixson DT, Manary MJ, Trehan I, Wall LLUndernutrition in pregnancy: Evaluation, management, and outcome in resource-limited areas
UpToDate, 2020 -
Trehan I, Manary MJManagement of moderate acute malnutrition in children in resource-limited settings
UpToDate, 2018 -
Trehan I, Manary MJManagement of uncomplicated severe acute malnutrition in children in resource-limited settings
UpToDate, 2017 -
Trehan I, Manary MJManagement of complicated severe acute malnutrition in children in resource-limited settings
UpToDate, 2017 -
Manary MJ, Trehan IKwashiorkor
BMJ Best Practice, 2016
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Presentations Title Event Location Date The unbearable lightness of being: Studies and stories of childhood malnutrition 43rd Annual Edward L. Pratt Lectures, Cincinnati Children’s Hospital Medical Center Cincinnati, USA May 2024 WHO wasting and nutritional oedema guidelines: Processes and lessons learned 2023 Action Against Hunger Research For Nutrition Conference Paris, France Nov. 2023 A frontline view of pediatric Ebola virus disease National Emerging Special Pathogens Training and Education Center (NETEC) Global Rounds Atlanta, USA Aug. 2023 Protein in practice USAID Specialized Food Aid Community of Practice 1st Annual Expanded Technical Meeting Washington, USA June 2023 A whirlwind tour of global malnutrition Thriving Brains and Bodies: Nutrition From Conception Through Infancy, Oregon Health and Science University Center for Global Child Health Research Symposium Portland, USA April 2022 Childhood malnutrition: 2 case studies Baylor College of Medicine and Texas Children's Hospital Foundations in Global Health Houston, USA April 2022 Childhood malnutrition: A whirlwind tour St. Louis University Department of Pediatrics Grand Rounds St. Louis, USA Feb. 2022 Hot topics in infectious disease: Sexually transmitted infections in infants Urgent Pediatric Problems: Bridging Office and Emergency Care Seattle, USA March 2021 Infections, immunity, and severe acute malnutrition University of Washington Department of Epidemiology Seminar Series Seattle, USA Feb. 2021 Global child health University of Hawai’i Department of Pediatrics Grand Rounds Honolulu, USA Nov. 2018 The unbearable lightness of being Society for Pediatric Research Presidential Scientific Plenary, 2018 Pediatric Academic Societies Meeting Toronto, Canada May 2018 A clinician’s approach to childhood diarrhea in the developing world 68th Annual American Association for Clinical Chemistry Annual Scientific Meeting and Clinical Expo Philadelphia, USA Aug. 2016 Ethics in laboratory medicine: an Ebola perspective American Society for Microbiology - Microbe 2016 Boston, USA June 2016 Improving the understanding of childhood malnutrition in sub-Saharan Africa University of Hawai’i Pacific Center for Emerging Infectious Diseases Research Seminar Honolulu, USA May 2016 A frontline view of Ebola Washington University in St. Louis Department of Pediatrics Grand Rounds St. Louis, USA Dec. 2015 Recent evidence on improving the management of moderate acute malnutrition MSF Canada 7th Annual Clinical Day Montréal, Canada June 2015 Some infectious thoughts on severe acute malnutrition MSF Canada 7th Annual Clinical Day Montréal, Canada June 2015 Home-based therapy for severe acute malnutrition 9th St. Louis Children’s Hospital Perspectives in Pediatrics Conference St. Louis, USA May 2015 MD + MPH Northwestern University 2015 MD/MPH Commencement Chicago, USA May 2015 Responding to emerging threats: Ebola outbreak management and preparedness 3rd Annual Washington University in St. Louis Global Health and Infectious Disease Conference St. Louis, USA April 2015 Legumes and growth 2014 Global Legume Innovation Lab Meeting Athens, Greece May 2014 Severe acute malnutrition Section on International Child Health Program, American Academy of Pediatrics 2013 National Conference and Exhibition Orlando, USA Oct. 2013 Malnutrition, infection, and the microbiome: A new approach and a new horizon The Lilliputian Surgical Society 53rd Annual Meeting St. Louis, USA Sept. 2013 A novel fortified blended flour, CSB++, is not inferior to lipid-based ready-to-use supplementary foods for the treatment of moderate acute malnutrition in Malawian children International Food Aid Development Conference Kansas City, USA May 2012 Systematic review and GRADE summary of findings: The use of intravenous blood and/or plasma infusions in severe dehydration and shock Third Nutrition Guidance Expert Advisory Group on Acute Malnutrition, Subgroup of Nutrition in the Life Course and Undernutrition, World Health Organization Geneva, Switzerland Feb. 2012 Systematic review and GRADE summary of findings: The management of diarrhea in community-based programs Third Nutrition Guidance Expert Advisory Group on Acute Malnutrition, Subgroup of Nutrition in the Life Course and Undernutrition, World Health Organization Geneva, Switzerland Feb. 2012 Preliminary findings: Randomized, double-blind, placebo-controlled trial evaluating the need for routine antibiotics as part of the outpatient management of severe acute malnutrition Third Nutrition Guidance Expert Advisory Group on Acute Malnutrition, Subgroup of Nutrition in the Life Course and Undernutrition, World Health Organization Geneva, Switzerland Feb. 2012 Systematic review and GRADE summary of findings: Care of HIV-infected children with severe acute malnutrition Third Nutrition Guidance Expert Advisory Group on Acute Malnutrition, Subgroup of Nutrition in the Life Course and Undernutrition, World Health Organization Geneva, Switzerland Feb. 2012 Acute childhood malnutrition in resource-limited settings CCHMC Global Health Speaker Series Cincinnati, USA April 2009 -
Grant Title Grantor Amount Award Date Epidemiology, biomarkers and risk stratification of young infants presenting to the emergency department with hypothermia Northwestern University $5150 2023 - 2024 Immune Reconstitution After Anthropometric Recovery from Severe Acute Malnutrition Children's Investment Fund Foundation $249,395 2023 - 2024 Addressing Wasting and Stunting in Infants and Young Children by Increasing the Coverage and Quality of Selected High Impact Interventions in Ethiopia UNICEF / Action Against Hunger USA $266,192 2022 - 2024 Technical Expertise to Countries in the East Asia Pacific Region to Integrate Prevention and Treatment Services for Wasting into National Health Systems UNICEF / Action Against Hunger UK $40,000 2021 - 2023 Lactoferrin and Lysozyme to Promote Nutritional, Clinical, and Enteric Recovery: A Factorial Placebo-controlled Randomized Trial Among Children with Diarrhea and Malnutrition Eunice Kennedy Shriver National Institute of Child Health and Human Development $3,039,375 2021 - 2025 Novel Sensor and Biomarkers for Diagnosis of Malaria Using Human Breath Bill and Melinda Gates Foundation $1,000,000 2016 - 2017 Optimizing Therapeutic Foods for Neurocognitive Development in Malnourished Children Children’s Discovery Institute of Washington University and St. Louis Children’s Hospital $467,811 2016 - 2019 Legumes and Growth USAID Feed the Future Innovation Lab for Collaborative Research on Grain Legumes $3,000,000 2014 - 2017 Innovative Interventions for Improving Childhood Growth and Environmental Enteropathy Children’s Discovery Institute of Washington University and St. Louis Children’s Hospital $300,000 2014 - 2019 Towards Noninvasive Diagnosis of Malaria Infection Through Exhaled Breath Analysis Children’s Discovery Institute of Washington University and St. Louis Children’s Hospital $449,233 2014 - 2017 Understanding and Ameliorating Environmental Enteropathy Children’s Discovery Institute of Washington University and St. Louis Children’s Hospital $699,457 2013 - 2016
Overview
- Board Certification(s)
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Pediatrics
Pediatric Emergency Medicine
Pediatric Infectious Diseases
- Medical/Professional School
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Northwestern University Feinberg School of Medicine, Chicago, IL
- Residency
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Cincinnati Children's Hospital Medical Center, Cincinnati, OH
- Fellowship
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Washington University School of Medicine, Saint Louis, MO
- Clinical Interests
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diarrhea, emerging infectious diseases, fevers of unknown origin, malaria, malnutrition, neglected tropical diseases, parasitic infections, point-of-care ultrasound, respiratory distess, sepsis, shock, trauma, travel medicine, tuberculosis
- Research Description
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acute malnutriton, adaptation of medical technologies for low-resource settings, beriberi, environmental enteric dysfunction, novel diagnostics for tropical diseases, stunting, wasting
- Research Focus Area
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Malnutrition, Global Health, Medical Education, Tropical Medicine