Indi Trehan, MD, MPH, DTM&H

Infectious Disease and Virology, Emergency Medicine

On staff since January 2020

Children's Title: Attending Physician

Academic Title: Associate Professor, Pediatrics; Adjunct Associate Professor, Global Health; Adjunct Associate, Professor of Epidemiology

Research Center: Center for Clinical and Translational Research

Biography
I am driven to improve the health of children in resource-limited settings. As such, my primary clinical interests within Emergency Medicine are in diarrhea, respiratory distress, sepsis, shock, and trauma. I am also very interested in the application of bedside ultrasound to patient care, both in resource-rich and underserved settings. Within Infectious Diseases, my primary clinical interests are in fevers of unknown origin, HIV, malaria, neglected tropical diseases, parasitic infections, travel medicine, and tuberculosis.

I have spent roughly half of my medical career working, researching, and teaching in a diverse array of settings around the world. My clinical work abroad includes directing an Ebola Treatment Centre in Sierra Leone, training the first cohort of emergency medicine residents in Haiti, and primary care in a Rohingya refugee camp in Bangladesh, but I am most passionate about training local health care providers in evidence-based, cost-effective care that maximizes survival and human potential. Most recently, I took an academic sabbatical to manage clinical operations in rural Liberia for Partners in Health and then to serve as the Director of Lao Friends Hospital for Children in 2017-2019, where I had the privilege of training the country's largest cohort of pediatricians, pediatric nurses, and pediatric nutritionists, before joining the University of Washington in 2020.

My major academic interests are in the development of a better understanding of the pathophysiology underlying chronic and acute childhood malnutrition, and in improving the diagnosis and treatment of malnourished children. The majority of my research experience in these domains has come in the conduct of large pragmatic clinical trials in rural African villages, as well as in smaller hospital-based cohort studies. I am fortunate to collaborate with colleagues in the Gut Health and Child Survival Scientific Priority Area, within the Global Center for Integrated Health of Women, Adolescents, and Children (Global WACh) in the Department of Global Health.
- Related Pages
- Department of Global Health Faculty Profile
- Department of Epidemiology Faculty Profile
Patient Testimonials
- Jennifer Seattle WA 09.18.21
  
  Dr. Indi was the absolute best we could hope for. Compassionate, super intelligent, amazingly fun with kids, so patient with us and all of our questions. He saved our 3 year old son with a rare infection (tularemia!) that nobody else seemed to know about. And he kept following up with us to make sure he was doing well many months later. When all hope was lost, he was there for us — many times over!
Recommend Indi Trehan, MD, MPH, DTM&H

Awards and Honors

Award Name	Awarded By	Award Date
Elected member	American Pediatric Society	2024
The Nutrition Society Paper of the Month for December 2022	The Nutrition Society	2022
David Fisher Award for Excellence in Safety Nominee (clinical individual)	Seattle Children’s Hospital Center for Quality and Patient Safety	2022
David Fisher Award for Excellence in Safety Nominee (clinical group - COVID Monoclonal Antibody Approval Committee)	Seattle Children’s Hospital Center for Quality and Patient Safety	2022
Award for Outstanding Faculty Teaching	University of Washington Pediatric Residency Program	2021 - 2022
Academic Achievement Award	Society for Academic Emergency Medicine Global Emergency Medicine Academy	2019
Society for Pediatric Research Outstanding New Member	Society for Pediatric Research	2018
Humanism in Medicine Award	Washington University in St. Louis School of Medicine	2016
Gold Humanism Honor Society Faculty Inductee	Washington University in St. Louis School of Medicine	2016
Outstanding Commitment to Teaching Award	Washington University in St. Louis Pediatrics Residency Program	2015 - 2016
Outstanding Subspecialty Teacher Award	Washington University in St. Louis Pediatrics Residency Program	2014 - 2015
Pediatric Clinical Educator Award	Washington University in St. Louis Emergency Medicine Residency Program	2013 - 2014
Pediatric Loan Repayment Program Award	National Institute of Child Health and Human Development	2010 - 2012
Ruth L. Kirschstein National Research Service Award	National Institute of Child Health and Human Development	2009 - 2011
Outstanding Fellow Teaching Award	Washington University in St. Louis Pediatrics Residency Program	2007 - 2008
Benzing/Lowe Award for Excellence in Critical Care	Cincinnati Children's Hospital Medical Center	2007
Samuel Dalinsky Memorial Award for the Outstanding Graduating Pediatric Resident	Cincinnati Children's Hospital Medical Center	2007
Chief Residents’ Award for Commitment to Excellence in Patient Care and Resident Support	Cincinnati Children's Hospital Medical Center	2007
Medical Student Research Training Fellowship	Howard Hughes Medical Institute	2000 - 2004
Chancellor's Scholarship	University of California, Berkeley	1994 - 1998

Publications
Manuscripts in Refereed Journals
- Smith TJ, Arnold CD, Fischer PR, Trehan I, Hiffler L, Sitthideth D, Stein-Wexler R, Yeh J, Jones KS, Hampel D, Tancredi DJ, Schick MA, McBeth CN, Tan X, Allen LH, Syasone S, Kounnavong S, Hess SY
  A predictive model for thiamine responsive disorders among infants and young children: Results from a prospective cohort study in Lao People's Democratic Republic
  The Journal of Pediatrics, 2024 : 268(-)113961
- Kearney JE, Thiel N, El-Taher A, Akhter S, Townes DA, Trehan I, Pottinger P
  Conflicts in Gaza and around the world create a perfect storm for infectious disease outbreaks
  PLOS Global Public Health, 2024 : 4(2)e0002927
- Hexom BJ, Quao NSA, Bandolin NS, Bonney J, Collier A, Dyal J, Lee JA, Nicholson BD, Rybarczyk MM, Rees CA, Roy CM, Bhaskar N, Kivlehan SM, Global Emergency Medicine Literature Review (GEMLR) Group
  Global emergency medicine: A scoping review of the literature from 2022
  Academic Emergency Medicine, 2024 : 31(1)71-85
- Ramgopal S, Graves C, Aronson PL, Cruz AT, Rogers A, RIsk Stratification for Hypothermic Infants (RISHI) study group
  Clinician management practices for infants with hypothermia presenting to the emergency department
  Pediatrics, 2023 : 152(6)e2023063000
- Shannon G, Lauer J, Nacer H, Neilson A, Haj-Hassan T, Shah BK, Jamieson J, Boukari Y, Bornstein S, Mennie N, Vergnano S, Elton L, Shah D, Gram L, Kadir A, Atraqchy Z, Trehan I, et al.
  A call to action: An open letter from global health professionals
  Social Medicine, 2023 : 16(3)152-154
- Schwartz DJ, Langdon A, Sun X, Langendorf C, Berthé F, Grais RF, Trehan I, Isanaka S, Dantas G
  Retrospective gut microbiome metagenomic analysis of a randomized placebo-controlled trial of amoxicillin for Nigerien children with severe acute malnutrition
  The Lancet Microbe, 2023 : 4(11)e931-e942
- Relan P, Garbern SC, O’Reilly G, Bills CB, Schultz M, Kivlehan S, Trehan I, Becker TK
  Emergency care interventions for paediatric severe acute respiratory infections in low- and middle- income countries: a systematic review and narrative synthesis
  Journal of Global Health, 2023 : 13(-)04065
- Poonai N, Cohen DM, MacDowell D, Mistry RD, Mintegi S, Craig S, Roland D, Miller M, Shavit M, Paediatric Emergency Research Netweorks (PERN) PAINT Study Group
  Sedation and analgesia for reduction of pediatric ileocolic intussusception
  JAMA Network Open, 2023 : 6(6)e2317200
- Odei Obeng-Amoako GA, Stobaugh H, Wrottesley SV, Khara T, Binns P, Trehan I, Black RE, Webb P, Mwangome M, Bailey J, Bahwere P, Dolan C, Boyd E, Briend A, Myatt MA, Lelijveld N
  How do children with severe underweight and wasting respond to treatment? A pooled secondary data analysis to inform future intervention studies
  Maternal & Child Nutrition, 2023 : 19(1)e13434
- Woeltje MM, Evanoff AB, Helmink BA, Culbertson DL, Maleta KM, Manary MJ, Trehan I
  Community-based management of acute malnutrition for infants under 6 months of age is safe and effective: Analysis of operational data
  Public Health Nutrition, 2023 : 26(1)246-255
- Vora SB, Englund JA, Trehan I, Waghmare A, Kong A, Adler A, Zerr DM
  Monoclonal antibody and antiviral therapy for early treatment of mild- to-moderate COVID-19 in high-risk children and adolescents
  The Pediatric Infectious Disease Journal, 2023 : 42(1)32-34
- Garbern SC, Relan P, O’Reilly GM, Bills CB, Schultz ML, Trehan I, Kivlehan SM, Becker TK
  A systematic review of acute and emergency care interventions for adolescents and adults with severe acute respiratory infections including COVID-19 in low- and middle-income countries
  Journal of Global Health, 2022 : 12(-)05039
- Kivlehan SM, Hexom BJ, Bonney J, Collier A, Nicholson BD, Quao NSA, Rybarczyk MM, Selvam A, Rees CA, Roy CM, Bhaskar N, Becker TK, Global Emergency Medicine Literature Review (GEMLR) Group
  Global emergency medicine: A scoping review of the literature from 2021
  Academic Emergency Medicine, 2022 : 29(10)1264-1274
- Noori N, Skrip LA, Oron AP, McCarthy KA, Proctor JL, Chabot-Couture G, Althouse BM, Phelan KPQ, Trehan I
  Potential impacts of mass nutritional supplementation on measles dynamics: a simulation study
  The American Journal of Tropical Medicine and Hygiene, 2022 : 107(4)863-872
- King S, D'Mello-Guyett L, Yakowenko E, Riems B, Gallandat K, Chabi SM, Mohamud FA, Ayoub K, Olad AH, Aliou B, Marshak A, Trehan I, Cumming O, Stobaugh H
  A multi-country, prospective cohort study to measure rate and risk of relapse among children recovered from severe acute malnutrition in Mali, Somalia, and South Sudan: A study protocol
  BMC Nutrition, 2022 : 8(-)90
- Tunҫ EM, Koid Jia Shin C, Usoro E, Thomas-Smith SE, Trehan I, Migita RT, Keilman AE
  Pediatric croup during the coronavirus disease 2019 Omicron variant surge
  The Journal of Pediatrics, 2022 : 247(8)147-149
- Engl M, Binns P, Trehan I, Lelijveld N, Angood C, McGrath M, Groce N, Kerac M
  Children living with disabilities are neglected from severe malnutrition protocols: A guideline review
  Archives of Disease in Childhood, 2022 : 107(7)637-643
- Park BL, Trehan I
  Amoxicillin dose and duration of treatment on the need for antibiotic re-treatment in children with community-acquired pneumonia
  JAMA, 2022 : 327(11)1089-1090
- Basu S, Copana R, Morales Jr R, Anugulruengkitt S, Puthanakit T, Maramba-Lazarte C, Williams P, Musembi J, Boga M, Issack M, Hokororo A, Falade AG, Trehan I, Molyneux E, Arscott-Mills T, Alemayehu T, Bryant PA
  Keeping it real: Antibiotic use problems and stewardship solutions in low- and middle-income countries
  The Pediatric Infectious Disease Journal, 2022 : 41(3S)S18-S25
- Trehan I, Kivlehan SM, Balhara KS, Bonney J, Hexom BJ, Pousson AY, Quao NSA, Rybarczyk MM, Selvam A, Nicholson BD, Bhaskar N, Becker TK, on behalf of the Global Emergency Medicine Literature Review (GEMLR) Group
  Global emergency medicine: A scoping review of the literature from 2020
  Academic Emergency Medicine, 2021 : 28(11)1328-1340
- Winders WT, Gabern S, Bills C, Relan P, Schultz M, Kivlehan S, Trehan I, Becker TK, McQuillan R
  The effects of mobile health on emergency care in low- and middle-income countries: A systematic review and narrative synthesis
  Journal of Global Health, 2021 : 11(1)04023
- Angood C, Kerac M, Black R, Briend A, Hanson K, Jarrett S, Manary M, McGrath M, Zagre N, Lelijveld N, Mayberry A, CHNRI Collaborators, Council of Reseach & Technical Advice on Acute Malnutrition (CORTASAM)
  Treatment of child wasting: Results of a child health and nutrition research initiative (CHNRI) prioritization exercise
  F1000Research, 2021 : 10(-)126
- Winders WT, Bustamante ND, Gabern SC, Bills C, Coker A, Trehan I, Osei-Ampofo M, Levine AC, on behalf of the Global Emergency Medicine Literature Review (GEMLR) Group
  Establishing the effectiveness of interventions provided to first responders to prevent and/or treat mental health effects of response to a disaster: A systematic review
  Disaster Medicine and Public Health Preparedness, 2021 : 15(1)115-126
- Trehan I, Kivlehan SM, Balhara KS, Hexom BJ, Pousson AY, Quao NSA, Rybarczyk MM, Selvam A, Bonney J, Bhaskar N, Becker TK, and on behalf of the Global Emergency Medicine Literature Review (GEMLR) Group
  Global emergency medicine: A review of the literature from 2019
  Academic Emergency Medicine, 2021 : 28(1)117-128
- D’Souza AW, Moodley-Govender E, Berla B, Kelkar T, Wang B,Sun X, Daniels B, Coutsoudis A, Trehan I, Dantas G
  Cotrimoxazole prophylaxis increases resistance gene prevalence and α-diversity but decreases ß-diversity in the gut microbiome of HIV-exposed, uninfected infants
  Clinical Infectious Diseases, 2020 : 71(11)2858-2868
- Trehan I
  The past informs the future: inpatient mortality in severe childhood malnutrition
  The American Journal of Clinical Nutrition, 2020 : 112(4)911-912
- Collins EM, Iroh Tam PY, Trehan I, Cartledge P, Bose A, Lanaspa M, Kidd P, Bassat Q
  Strengthening health systems and improving the capacity of pediatric care centers to respond to epidemics such as COVID-19 in resource-limited settings
  Journal of Tropical Pediatrics, 2020 : 66(4)357-365
- Trehan I, Mouayaxeng S, Nigogosyan MA
  Axillary calcification due to Bacillus Calmette-Guérin vaccination
  The Journal of Pediatrics, 2020 : 222(2)218-219
- Trehan I
  Anthropometry’s promise and pitfalls in the diagnosis of undernutrition among infants
  Archives of Disease in Childhood, 2020 : 105(6)522-523
- Elenga N, Nacher M, Trehan I
  The imperative of dengue vaccination for children with sickle cell disease
  Journal of Tropical Pediatrics, 2020 : 66(3)245-247
- Suchdev PS, Trehan I
  Optimizing iron supplementation for children with severe malaria
  The American Journal of Clinical Nutrition, 2020 : 111(5)939-940
- Ordiz MI, Janssen S, Humphrey G, Ackermann G, Stephenson K, Agapova S, Divala O, Kaimila Y, Maleta K, Zhong C, Knight R, Trehan I, Tarr PI, Rusconi B, Manary MJ
  The effect of legume supplementation on the gut microbiota in rural Malawian infants aged 6 to 12 months
  The American Journal of Clinical Nutrition, 2020 : 111(4)884-892
- Hess SY, Smith TJ, Fischer PR, Trehan I, Hiffler L, Arnold CD, Sitthideth D, Tancredi DJ, Schick MA, Yeh J, Stein-Wexler R, McBeth CN, Tan X, Nhiacha K, Kounnavong S
  Establishing a case definition of thiamine responsive disorders (TRD) among infants in Lao PDR: protocol for a prospective cohort study
  BMJ Open, 2020 : 10(2)e036539
- Frison S, Angood C, Khara T, Bahwere P, Black RE, Briend A, Connell N, Fenn B, Isanaka S, James P, Kerac M, Mayberry A, Myatt M, Dolan C, wasting prevention Working Group Collaborators
  Prevention of child wasting: Results of a Child Health & Nutrition Research Initiative (CHNRI) prioritisation exercise
  PLoS ONE, 2020 : 15(2)e0228151
- Schulze KV, Swaminathan S, Howell S, Jajoo A, Lie NC, Brown O, Sadat R, Hall N, Zhao L, Marshall K, May T, Reid ME, Taylor-Bryan C, Wang X, Belmont JW, Guan Y, Manary MJ, Trehan I, McKenzie CA, Hanchard NA
  Edematous severe acute malnutrition is characterized by hypomethylation of DNA
  Nature Communications, 2019 : 105791
- Natarajan DK, Homthavong P, Trehan I
  Small bowel obstruction secondary to wild banana seed ingestion
  The American Journal of Tropical Medicine and Hygiene, 2019 : 101(6)1195-1196
- Trehan I, Osei-Ampofo M, Balhara KS, Hexom BJ, Kivlehan SM, Modi P, Pousson AY, Selvam A, Quao NSA, Cho DK, Becker TK, Levine AC, and on behalf of the Global Emergency Medicine Literature Review (GEMLR) Group
  Global emergency medicine: a review of the literature from 2018
  Academic Emergency Medicine, 2019 : 26(10)1186-1196
- Trehan I, Grabowsky M, Schenker I
  Oral rehydration therapy and zinc: looking back and looking ahead
  Journal of Tropical Pediatrics, 2019 : 65(5)417-420
- Woeltje MM, Newland JG, Trehan I
  World Health Organization treatment recommendations for nonsevere fast-breathing pneumonia need to be updated
  JAMA Pediatrics, 2019 : 173(6)607-608
- Palmer ES, Saysamoneyeu P, Siu JM, Thammaseng A, Trehan I
  Down boy! A case of acute abdomen following a dog bite to the scrotum
  BMC Pediatrics, 2019 : 19169
- Balhara K, Bustamante N, Selvam A, Winders W, Coker A, Trehan I, Becker T, Levine A
  Bystander assistance for trauma victims in low- and middle-income countries: a systematic review of prevalence and training interventions
  Prehospital Emergency Care, 2019 : 23(3)389-410
- Kaimila Y, Pitman RT, Divala O, Hendrixson DT, Stephenson KB, Agapova S, Trehan I, Maleta K, Manary MJ
  Development of acute malnutrition despite nutritional supplementation in Malawi
  Journal of Pediatric Gastroenterology and Nutrition, 2019 : 68(5)734-737
- Cheng WD, Wold KJ, Bollinger LB, Ordiz MI, Shulman RJ, Maleta KM, Manary MJ, Trehan I
  Supplementation with lactoferrin and lysozyme ameliorates environmental enteric dysfunction: a double-blind, randomized, placebo-controlled trial
  The American Journal of Gastroenterology, 2019 : 114(4)671-678
- Berna AZ, Schaber CL, Bollinger LB, Mwale M, Mlotha-Mitole R, Trehan I, Odom John AR
  Comparison of breath sampling methods: a post hoc analysis from observational cohort studies
  Analyst, 2019 : 144(6)2026-2033
- Kaimila Y, Davila O, Agapova SE, Stephenson KB, Thakwalakwa C, Trehan I, Manary MJ, Maleta KM
  Consumption of animal-source protein is associated with improved height-for-age z scores in rural Malawian children aged 12-36 months
  Nutrients, 2019 : 11(2)480
- Sultan M, Mengitsu G, Debebe F, Azazh A, Trehan I
  The burden on emergency centres to provide care for critically ill patients in Addis Ababa, Ethiopia
  African Journal of Emergency Medicine, 2018 : 8(4)150-154
- Becker TK, Trehan I, Hayward AS, Hexom BJ, Kivlehan S, Lunney KM, Modi P, Osei-Ampofo M, Pousson A, Cho DK, Levine AC, and on behalf of the Global Emergency Medicine Literature Review (GEMLR) Group
  Global emergency medicine: a review of the literature from 2017
  Academic Emergency Medicine, 2018 : 25(11)1287-1298
- Bassat Q, Bose A, Cartledge P, Collins EM, Jullien S, Lanaspa M, Simkiss D, Trehan I
  Commitment to publication quality and integrity: a message from the journal’s editorial board
  Journal of Tropical Pediatrics, 2018 : 64(5)355-359
- Ngoma TN, Chimimba UK, Mwangwela AM, Thakwalakwa C, Maleta KM, Manary MJ, Trehan I
  Effect of cowpea flour processing on the chemical properties and acceptability of a novel cowpea blended maize porridge
  PLoS ONE, 2018 : 13(7)e0200418
- Stobaugh HC, Rogers BL, Rosenberg IH, Webb P, Maleta KM, Manary MJ, Trehan I
  Children with poor linear growth are at risk for repeated relapse to wasting after recovery from moderate acute malnutrition
  The Journal of Nutrition, 2018 : 148(6)974-979
- Trehan I, Bassat Q
  The unbearable lightness of being malnourished: severe acute malnutrition remains a neglected tropical disease
  Journal of Tropical Pediatrics, 2018 : 64(3)169-173
- Schaber C, Katta N, Bollinger LB, Mwale M, Mlotha-Mitole R, Trehan I, Raman B, Odom John AR
  Breathprinting reveals malaria-associated biomarkers and mosquito attractants
  The Journal of Infectious Diseases, 2018 : 217(10)1553-1560
- Stobaugh HC, Rogers BL, Webb P, Rosenberg IH, Thakwalaka C, Maleta KM, Trehan I, Manary M
  Household-level factors associated with relapse following discharge from treatment for moderate acute malnutrition
  British Journal of Nutrition, 2018 : 119(9)1039-1046
- Trehan I, De Silva SC
  Management of Ebola virus disease in children
  Infectious Disease Clinics of North America, 2018 : 32(1)201-214
- Trehan I
  Rotavirus vaccines: a social injustice story
  Journal of Tropical Pediatrics, 2018 : 64(1)1-3
- Agapova SE, Stephenson KB, Divala O, Kaimila Y, Maleta KM, Thakwalakwa C, Ordiz MI, Trehan I, Manary MJ
  Additional common bean in the diet of Malawian children does not affect linear growth, but reduces intestinal permeability
  The Journal of Nutrition, 2018 : 148(2)267-274
- Semba RD, Trehan I, Li X, Salem Jr. N, Moaddel R, Ordiz MI, Maleta KM, Kraemer K, Manary MJ
  Low serum ω-3 and ω-6 polyunsaturated fatty acids and other metabolites are associated with poor linear growth in young children from rural Malawi
  The American Journal of Clinical Nutrition, 2017 : 106(6)1490-1499
- Stephenson KB, Agapova SE, Divala O, Kaimila Y, Maleta KM, Thakwalakwa C, Ordiz MI, Trehan I, Manary MJ
  Complementary feeding with cowpea reduces growth faltering in rural Malawian infants: a blind, randomized controlled clinical trial
  The American Journal of Clinical Nutrition, 2017 : 106(6)1500-1507
- Le Doare K, O’Driscoll M, Turner K, Seedat F, Russell NJ, Seale AC, Heath PT, Lawn JE, Baker CJ, Bartlett L, Cutland C, Gravett MG, Ip M, Madhi SA, Rubens CE, Saha SK, Schrag S, Sobanjo-ter Meulen A, Vekemans J, Kampmann B, for the GBS Intrapartum Antibiotic Investigator Group
  Intrapartum antibiotic chemoprophylaxis policies for the prevention of Group B Streptococcal disease worldwide: systematic review
  Clinical Infections Diseases, 2017 : 65(S2)S143-S151
- Cheng WD, Wold KJ, Benzoni NS, Thakwalakwa C, Maleta KM, Manary MJ, Trehan I
  Lactoferrin and lysozyme to reduce environmental enteric dysfunction and stunting in Malawian children: study protocol for a randomized controlled trial
  Trials, 2017 : 18523
- Borresen EC, Zhang L, Trehan I, Nealon NJ, Maleta KM, Manary MJ, Ryan EP
  The nutrient and metabolite profile of three complementary legume foods with potential to improve gut health in rural Malawian children
  Current Developments in Nutrition, 2017 : 1(10)e001610
- Callaghan-Gillespie M, Schaffner AA, Garcia P, Fry J, Eckert R, Malek S, Trehan I, Thakwalakwa C, Maleta KM, Manary MJ, Papathakis PC
  Trial of ready to use supplemental food and corn soy blend in pregnant Malawian women with moderate malnutrition: a randomized, controlled clinical trial
  The American Journal of Clinical Nutrition, 2017 : 106(4)1062-1069
- Bhutta ZA, Berkley JA, Bandsma RHJ, Kerac M, Trehan I, Briend A
  Severe childhood malnutrition
  Nature Reviews Disease Primers, 2017 : 317067
- Becker TK, Hansoti B, Bartels S, Hayward A, Hexon B, Lunney K, Marsh R, Osei-Ampofo M, Trehan I, Chang J, Levine AC, and on behalf of the Global Emergency Medicine Literature Review (GEMLR) Group
  Global emergency medicine: a review of the literature from 2016
  Academic Emergency Medicine, 2017 : 24(9)1150-1160
- Stobaugh HC, Bollinger LB, Adams SE, Crocker AH, Grise JB, Kennedy JA, Thakwalakwa C, Maleta KM, Dietzen DJ, Manary MJ, Trehan I
  Effect of a package of health and nutrition services on sustained recovery in children after moderate acute malnutrition and factors related to sustaining recovery: a cluster randomized trial
  The American Journal of Clinical Nutrition, 2017 : 106(2)657-666
- Heikens GT, Manary MJ, Trehan I
  African children with severe pneumonia remain at high risk for death even after discharge
  Paediatric and Perinatal Epidemiology, 2017 : 31(3)243-244
- Semba RD, Gonzalez-Freire M, Moaddel R, Trehan I, Maleta KM, Khadeer M, Ordiz MI, Ferrucci L, Manary MJ
  Environmental enteric dysfunction is associated with altered bile acid metabolism
  Journal of Pediatric Gastroenterology and Nutrition, 2017 : 64(4)536-540
- Semba RD, Trehan I, Li X, Moaddel R, Ordiz MI, Maleta KM, Kraemer K, Shardell M, Ferrucci L, Manary M
  Environmental enteric dysfunction is associated with carnitine deficiency and altered fatty acid oxidation
  EBioMedicine, 2017 : 1757-66
- Ordiz MI, Stephenson K, Agapova S, Wylie KM, Maleta K, Martin J, Trehan I, Tarr PI, Manary MJ
  Environmental enteric dysfunction and the fecal microbiota in Malawian children
  The American Journal of Tropical Medicine and Hygiene, 2017 : 96(2)473-476
- Wang AZ, Shulman RJ, Crocker AH, Thakwalakwa C, Maleta KM, Devaraj S, Manary MJ, Trehan I
  A combined package of zinc, multiple micronutrients, and albendazole does not ameliorate environmental enteric dysfunction or stunting in rural Malawian children in a double-blind, randomized, controlled trial
  The Journal of Nutrition, 2017 : 147(1)97-103
- Di Giovanni V, Bourdon C, Wang DX, Seshadri S, Senga E, Versloot CJ, Voskuijl W, Semba RD, Trehan I, Moaddel R, Ordiz MI, Zhang L, Parkinson J, Manary MJ, Bandsma RH
  Metabolomic changes in serum of children with different clinical diagnoses of malnutrition
  The Journal of Nutrition, 2016 : 146(12)2436-2444
- Ordiz MI, Shaikh N, Trehan I, Maleta K, Stauber J, Shulman R, Devaraj S, Tarr PI, Manary MJ
  Environmental enteric dysfunction is associated with poor linear growth and can be identified by host fecal mRNAs
  Journal of Pediatric Gastroenterology and Nutrition, 2016 : 63(5)453-459
- Becker TK, Hansoti B, Bartels S, Bisanzo M, Jacquet GA, Lunney K, Marsh R, Osei-Ampofo M, Trehan I, Lam C, Levine AC, and on behalf of the Global Emergency Medicine Literature Review (GEMLR) Group
  Global emergency medicine: a review of the literature from 2015
  Academic Emergency Medicine, 2016 : 23(10)1183-1191
- Bollinger LB, Trehan I
  A courageous report on the management of malnutrition
  Nutrients, 2016 : 8(10)603
- Trehan I, Goldbach HS, LaGrone LN, Meuli GJ, Wang RJ, Maleta KM, Manary MJ
  Antibiotics as part of the management of severe acute malnutrition
  Malawi Medical Journal, 2016 : 28(3)123-130
- Semba RD, Trehan I, Freire-Gonzalez M, Kraemer K, Moaddel R, Ordiz MI, Ferrucci L, Manary MJ
  Perspective: the potential role of essential amino acids and the mechanistic target of rapamycin complex 1 (mTORC1) pathway in the pathogenesis of child stunting
  Advances in Nutrition, 2016 : 7(5)853-865
- Trehan I, Kelly P, Shaikh N, Manary MJ
  New insights into environmental enteric dysfunction
  Archives of Disease in Childhood, 2016 : 101(8)741-744
- Trehan I, Schechtman KB, Manary MJ
  Amoxicillin for severe acute malnutrition in children
  The New England Journal of Medicine, 2016 : 375(2)191
- Trehan I, Manary MJ
  An important chapter in the infection-malnutrition story
  The Lancet Global Health, 2016 : 4e430-e431
- Semba RD, Zhang P, Gonzalez-Freire M, Moaddel R, Trehan I, Maleta KM, Ordiz MI, Ferrucci L, Manary MJ
  The association of serum choline with linear growth failure in young children from rural Malawi
  The American Journal of Clinical Nutrition, 2016 : 104(7)191-197
- Semba RD, Shardell M, Trehan I, Moaddel R, Maleta KM, Ordiz MI, Kraemer K, Khadeer M, Ferrucci L, Manary MJ
  Metabolic alterations in children with environmental enteric dysfunction
  Scientific Reports, 2016 : 628009
- Semba RD, Shardell M, Ashour FA, Moaddel R, Trehan I, Maleta KM, Ordiz MI, Kraemer K, Khadeer MA, Ferrucci L, Manary MJ
  Child stunting is associated with low circulating essential amino acids
  EBioMedicine, 2016 : 6246-252
- Stobaugh HS, Ryan KN, Kennedy JA, Grise JB, Crocker AH, Thakwalakwa C, Litkowski PE, Maleta KM, Manary MJ, Trehan I
  Including whey protein and whey permeate in ready-to-use supplementary food improves recovery rates in children with moderate acute malnutrition: A randomized double-blinded clinical trial
  The American Journal of Clinical Nutrition, 2016 : 103(3)926-933
- Trehan I, Kelly T, Marsh RH, George PM, Callahan CW
  Moving towards a more aggressive and comprehensive model of care for children with Ebola virus disease
  The Journal of Pediatrics, 2016 : 170(1)28-33.e7
- Glaser E, Davis S, Flomo C, Sliney A, Tiah MW, Barron K, Balarabe AD, Bearse E, Brilliant B, Brownie S, Chapman S, Conteh S, Churchill R, Cunningham S, Daost P, Downes EA, English CR, Ferranti EP, Foster J, Galante ME, Garland J, Germain M, Ghahreman A, Gimbel S, Goldman D, Haileyesus MD, Hall A, Hall E, Hann K, Headrick E, Hickox K, Huster K, Jones EA, Kalal M, Kaonga NN, Kardas-Nelson M, Kloepper D, Lee J, Leffers J, McDermott-Levy R, Maher MD, Matarrese P, Mead A, Michaels A, Mondaye HNS, Nyuma SJ, Phillips J, Pohl JM, Reilly CM, Rodriguez J, Rollosson M, Sarchet N, Schicker RS, Schlough GW, Sliney A, Sonenberg A, Spray K, Subah MK, Sullivan B, Traisci-Marandola D, Trehan I, Wolf KA
  The Harvard-LSHTM panel on the global response to Ebola report
  The Lancet, 2016 : 387(10021)848
- Blanton LV, Charbonneau MR, Salih T, Barratt MJ, Venkatesh S, Ilkaveya O, Subramanian S, Manary MJ, Trehan I, Jorgensen JM, Fan Y, Henrissat B, Leyn SA, Rodionov DA, Osterman AL, Maleta KM, Newgard CB, Ashorn P, Dewey KG, Gordon JI
  Gut bacteria that rescue growth impairments transmitted by microbiota from undernourished children
  Science, 2016 : 351(6275)aad3311
- Yu J, Ordiz MI, Stauber J, Shaikh N, Trehan I, Barnell E, Head RD, Maleta K, Tarr PI, Manary MJ
  Environmental enteric dysfunction includes a broad spectrum of inflammatory responses and epithelial repair processes
  Cellular and Molecular Gastroenterology and Hepatology, 2016 : 2(2)158-174.e1
- Trehan I, Benzoni NS, Wang AZ, Bollinger LB, Ngoma TN, Chimimba UK, Stephenson KB, Agapova SE, Maleta KM, Manary MJ
  Common beans and cowpeas as complementary foods to reduce environmental enteric dysfunction and stunting in Malawian children: protocol for two randomized controlled trials
  Trials, 2015 : 16(1)520
- Reyes A, Blanton LV, Cao S, Zhao G, Manary M, Trehan I, Smith MI, Wang D, Virgin HW, Rohwer F, Gordon JI
  Gut DNA viromes of Malawian twins discordant for severe acute malnutrition
  Proceedings of the National Academy of Sciences of the United States of America, 2015 : 112(38)11941-11946
- Horst JA, Trehan I, Warner BW, Cohn BG
  Can children with uncomplicated acute appendicitis be treated with antibiotics instead of an appendectomy?
  Annals of Emergency Medicine, 2015 : 66(2)119-122
- Becker TK, Bartels S, Hansoti B, Jacquet GA, Lunney K, Marsh R, Osei-Ampofo M, Lam C, Levine AC, and on behalf of the Global Emergency Medicine Literature Review (GEMLR) Group
  Global emergency medicine: a review of the literature from 2014
  Academic Emergency Medicine, 2015 : 22(8)976-984
- Hsieh JC, Liu L, Zeilani M, Ickes S, Trehan I, Maleta K, Craig C, Thakwalakwa C, Singh L, Brenna JT, Manary MJ
  High oleic ready-to-use therapeutic food maintains docosaheaenoic acid status in severe malnutrition: a randomized, blinded trial
  Journal of Pediatric Gastroenterology and Nutrition, 2015 : 61(1)138-143
- Brenna JT, Akomo P, Bahwere P, Berkley JA, Calder PC, Jones KD, Liu L, Manary M, Trehan I, Briend A
  Balancing omega-6 and omega-3 fatty acids in ready-to-use therapeutic foods (RUTF)
  BMC Medicine, 2015 : 13117
- Angood C, McGrath M, Mehta S, Mwangome M, Lung'aho M, Roberfroid D, Perry A, Wilkinson C, Israel A-D, Bizoueme C, Haider R, Seal A, Berkley J, Kerac M, MAMI Working Group
  Research priorities to improve the management of acute malnutrition in infants aged <6 months (MAMI)
  PLOS Medicine, 2015 : 12(4)e1001812
- Iannotti LL, Trehan I, Clitheroe KL, Manary MJ
  Diagnosis and treatment of severely malnourished children with diarrhoea
  Journal of Paediatrics and Child Health, 2015 : 51(4)387-395
- Trehan I, Banerjee S. Murray E, Ryan KN, Thakwalakwa C, Maleta KM, Manary MJ
  Extending supplementary feeding for children under five with moderate acute malnutrition leads to lower relapse rates
  Journal of Pediatric Gastroenterology and Nutrition, 2015 : 60(4)544-549
- Trehan I, Manary MJ
  Management of severe acute malnutrition in low-income and middle-income countries
  Archives of Disease in Childhood, 2015 : 100(3)283-287
- Kau AL, Planer JD, Liu J, Rao S, Yatsunenko T, Trehan I, Manary MJ, Liu T-C, Stappenbeck TS, Maleta KM, Ashorn P, Dewey KG, Houpt ER, Hsieh CS, Gordon JI
  Functional characterization of IgA-targeted bacterial taxa from malnourished Malawian children that produce diet-dependent enteropathy
  Science Translational Medicine, 2015 : 7(276)276ra24
- Smith HE, Ryan KN, Stephenson KB, Westcott C, Thakwalakwa C, Maleta K, Cheng JY, Brenna JT, Shulman RJ, Trehan I, Manary MJ
  Multiple micronutrient supplementation transiently ameliorates environmental enteropathy in Malawian children aged 12–35 months in a randomized controlled clinical trial
  The Journal of Nutrition, 2014 : 144(12)2059-2065
- Ryan KN, Stephenson KB, Trehan I, Shulman RJ, Thakwalakwa C, Murray E, Maleta K, Manary M
  Zinc or albendazole attenuates the progression of environmental enteropathy: a randomized controlled trial
  Clinical Gastroenterology and Hepatology, 2014 : 12(9)1507-1513
- Becker TK, Jacquet GA, Marsh R, Schroeder ED, Foran M, Bartels S, Duber HC, Cockrell H, Levine AC, and on behalf of the Global Emergency Medicine Literature Review (GEMLR) Group
  Global emergency medicine: a review of the literature from 2013
  Academic Emergency Medicine, 2014 : 21(7)810-817
- Gough EK, Moodie EEM, Prendergast AJ, Johnson SMA, Humphrey JH, Stoltzfus RJ, Walker AS, Trehan I, Gibb DM, Goto R, Tahan S, de Morais MB, Manges AR
  The impact of antibiotics on growth in children in low and middle-income countries: a systematic review and meta-analysis of randomised controlled trials
  BMJ, 2014 : 348g2267
- Iannotti LL, Trehan I, Manary MJ
  Review of the safety and efficacy of vitamin A supplementation in the treatment of children with severe acute malnutrition
  Nutrition Journal, 2013 : 12125
- Trehan I, Maleta KM, Manary MJ
  Antibiotics for uncomplicated severe malnutrition
  The New England Journal of Medicine, 2013 : 368(25)2436-2437
- Wang RJ, Trehan I, LaGrone LN, Weisz AJ, Thakwalakwa CM, Maleta KM, Manary MJ
  Investigation of food acceptability and feeding practices for lipid nutrient supplements and blended flours used to treat moderate malnutrition
  Journal of Nutrition Education and Behavior, 2013 : 45(3)258-263
- Chang CY, Trehan I, Wang RJ, Thakwalakwa C, Maleta K, Deitchler M, Manary MJ
  Children successfully treated for moderate acute malnutrition remain at risk for malnutrition and death in the subsequent year after recovery
  The Journal of Nutrition, 2013 : 143(2)215-220
- Smith MI, Yatsunenko T, Manary MJ, Trehan I, Mkakosya R, Cheng J, Kau AL, Rich SS, Concannon P, Mychaleckyj JC, Liu J, Houpt E, Li JV, Holmes E, Nicholson J, Knights D, Ursell LK, Knight R, Gordon JI
  Gut microbiomes of Malawian twin pairs discordant for kwashiorkor
  Science, 2013 : 339(6119)548-554
- Trehan I, Goldbach HS, LaGrone LN, Meuli GJ, Wang RJ, Maleta KM, Manary MJ
  Antibiotics as part of the management of severe acute malnutrition
  The New England Journal of Medicine, 2013 : 368(5)425-435
- Yatsunenko T, Rey FE, Manary MJ, Trehan I, Dominguez-Bello MG, Contreras M, Magris M, Hidalgo G, Baldassano RN, Anokhin AP, Heath AC, Warner B, Reeder J, Kuczynski J, Caporaso JG, Lozupone CA, Lauber C, Clemente JC, Knights D, Knight R, Gordon JI
  Human gut microbiome viewed across age and geography
  Nature, 2012 : 486(7402)222-227
- Trehan I, O’Hare BA, Phiri A, Heikens GT
  Challenges in the management of HIV-infected malnourished children in sub-Saharan Africa
  AIDS Research and Treatment, 2012 : 2012790786
- LaGrone LN, Trehan I, Meuli GJ, Wang RJ, Thakwalakwa C, Maleta K, Manary MJ
  A novel fortified blended flour, CSB++, is not inferior to lipid-based ready-to-use supplementary foods for the treatment of moderate acute malnutrition in Malawian children
  The American Journal of Clinical Nutrition, 2012 : 95(1)212-219
- Weisz A, Meuli G, Thakwalakwa C, Trehan I, Maleta K, Manary M
  The duration of diarrhea and fever are associated with growth faltering in rural Malawian children aged 6-18 months
  Nutrition Journal, 2011 : 1025
- Stadler LP, Donauer S, Rice M, Trehan I, Salisbury S, Staat MA
  Factors associated with protective antibody levels to vaccine preventable diseases in internationally adopted children
  Vaccine, 2010 : 29(1)95-103
- Oakley E, Reinking J, Sandige H, Trehan I, Kennedy G, Maleta K, Manary M
  A ready-to-use therapeutic food with 10% milk content is less effective than one with 25% milk content in the treatment of severely malnourished children
  The Journal of Nutrition, 2010 : 140(12)2248-2252
- Staat MA, Stadler LP, Donauer S, Trehan I, Rice M, Salisbury S
  Serologic testing to verify the immune status of internationally adopted children against vaccine preventable diseases
  Vaccine, 2010 : 28(50)7947-7955
- Trehan I, Amthor RE, Maleta K, Manary MJ
  Evaluation of the routine use of amoxicillin as part of the home-based treatment of severe acute malnutrition
  Tropical Medicine & International Health, 2010 : 15(9)1022-1028
- Trehan I, Meuli GJ
  Mango contact allergy
  Journal of Travel Medicine, 2010 : 17(4)284
- Trehan I, Shulman RJ, Ou CN, Maleta K, Manary MJ
  A randomized, double-blind, placebo-controlled trial of rifaximin, a non-absorbable antibiotic, in the treatment of tropical enteropathy
  The American Journal of Gastroenterology, 2009 : 104(9)2326-2333
- Trehan I, Fritz SA
  Group B Streptococcus vertebral osteomyelitis-discitis in an immunocompetent adolescent
  The Pediatric Infectious Disease Journal, 2009 : 28(6)552-553
- Trehan I, Turpin BK
  Neonatal respiratory distress due to bilateral dacrocystoceles
  The Journal of Pediatrics, 2008 : 153(3)438
- Trehan I, Meinzen-Derr JK, Jamison L, Staat MA
  Tuberculosis screening in internationally adopted children: the need for initial and repeat testing
  Pediatrics, 2008 : 122(1)e7-e14
- Trehan I, Piskur JR, Prystowsky JJ
  Collaboration between medical students and NGOs: a new model in international health education
  Medical Education, 2003 : 37(11)1031
- Trehan I, Morandi F, Blaszczak LC, Shoichet BK
  Using steric hindrance to design new inhibitors of class C β-lactamases
  Chemistry & Biology, 2002 : 9(9)971-980
- Beadle BM, Trehan I, Focia PJ, Shoichet BK
  Structural milestones in the reaction pathway of an amide hydrolase: substrate, acyl, and product complexes of cephalothin with AmpC β-lactamase
  Structure, 2002 : 10(3)413-424
- Trehan I, Beadle BM, Shoichet BK
  Inhibition of AmpC β-lactamase through a destabilizing interaction in the active site
  Biochemistry, 2001 : 40(27)7992-7999
Book Chapters
- Manary MJ, Trehan I
  Severe Malnutrition
  Goldman-Cecil Medicine 27th edition, 2024
- Trehan I
  Infectious Diseases I
  Pediatric Emergency Medicine Question Review Book 2023, 2023
- Trehan I
  Scarlet Fever
  Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020
- Trehan I
  Acute Rheumatic Fever
  Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020
- Trehan I
  Periorbital Cellulitis
  Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020
- Spectorsky KA, Trehan I
  HIV/AIDS
  Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020
- Trehan I
  Herpes Simplex
  Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020
- Trehan I
  Croup
  Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020
- Trehan I
  Conjunctivitis, Neonatal
  Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020
- Trehan I
  Cat Scratch Disease
  Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020
- Trehan I
  Arthritis, Septic
  Fleisher and Ludwig’s 5-Minute Pediatric Emergency Medicine Consult 2nd edition, 2020
- Manary MJ, Trehan I
  Protein-Energy Malnutrition
  Goldman-Cecil Medicine 26th edition, 2019
- Trehan I, George PM, Callahan CW
  Comprehensive Clinical Care for Children with Ebola
  Pregnant in the Time of Ebola: Women and Their Children in the 2013-2015 West African Epidemic, 2019
- Trehan I, Manary MJ
  Childhood Undernutrition in Resource-Limited Settings
  Rudolph’s Pediatrics 23rd edition, 2018
- Ryan E, Trehan I, Smith K, Manary M
  Dietary Health Benefits, Phytochemicals and Anti-Nutritional Factors in Grain Legumes
  Achieving Sustainable Cultivation of Grain Legumes, 2018
- Manary MJ, Trehan I
  Protein-Energy Malnutrition
  Goldman-Cecil Medicine 25th edition, 2015
Manuscripts Submitted
- Wang ML, Trehan I
  Epidemiology and risk stratification of young infants presenting to the emergency department with hypothermia
  2024 Apr 21
- Sundararaman SA, Hanze Villavicencio KL, Roper B, Wang1 Z, Davis AKF, Mayhew JA, Wang ML, Tang NL, Soma VL, Shust GF, Feeney ME, Trehan I, Weatherhead JE, John CC, Gerber JS, Odom John AR
  Post-artesunate delayed hemolysis in pediatric malaria patients in the United States
  2024 Apr 15
- Hess SY, Smith TJ, Arnold CD, Jones KS, Hampel D, Hiffler L, Trehan I, Fischer PR, Meadows SR, Parkington DA, Brown KH, Sitthideth D, Tan X, Koulman A, Allen LH, Kounnavong S
  Assessment of erythrocyte transketolase, whole blood thiamine diphosphate and human milk thiamine concentrations to identify children responding favorably to therapeutic thiamine administration: Findings from the Lao Thiamine Study, a prospective cohort study
  2024 Mar 19
- Schwinger C, Kaldenbach S, Berkley JA, Walson JL, Argaw A, Chowdhury R, Strand TA, Rollins N, WHO Risk Stratification Working Group (WHO-RSWG)
  Cohort profile: The WHO Child Mortality Risk Stratification Multi-Country Pooled Cohort (WHO-CMRS) to identify predictors of mortality through early childhood
  2024 Feb 7
- King S, Marshak A, D’Mello-Guyett L, Yakowenko E, Chabi SM, Samake S, Bunkembo M, Diarra S, Mohamud FA, Omar MS, Lamwaka NG, Gose M, Ayoub K, Olad AH, Aliou B, Trehan I, Cumming O, Stobaugh H
  Rates and risk factors for relapse among children recovered from severe acute malnutrition: Results from a multi-country, prospective controlled cohort study in Mali, South Sudan, and Somalia
  2023 Dec 19
- Tickell KD, Tiwari R, Yoshioka E, Otieno J, Shah A, Richardson BA, Keter L, Okello M, Nyabinda C, Trehan I, McGrath CJ, Means AR, Houpt E, Liu J, Platts-Mills J, Njunge JM, Rwigi D, Diakhate MM, Nyaoke J, Ochola E, John-Stewart GC, Walson JL, Pavlinac PB, Singa BO
  Lactoferrin and lysozyme to promote nutritional, clinical, and enteric recovery: A protocol for a factorial, blinded, placebo-controlled randomized trial among children with diarrhea and malnutrition (the Boresha Afya trial)
  2023 Aug 31
Other Publications
- Goday PS, Trehan I
  Malnutrition in children in resource-limited settings: Clinical assessment
  UpToDate, 2024
- Knee J, D’Mello-Guyett L, Grignard L, Myers A, King S, Agong J, Gose M, Lamaka NG, Marshak A, Trehan I, Ayoub K, Stobaugh H, Cumming O
  Enteric pathogen detection among children discharged from outpatient treatment for severe acute malnutrition and associations with subsequent relapse in South Sudan
  OSF Preprints, 2024 Apr 18
- Hendrixson DT, Manary MJ, Trehan I, Wall LL
  Undernutrition in pregnancy: Evaluation, management, and outcome in resource-limited areas
  UpToDate, 2020
- Trehan I, Manary MJ
  Management of moderate acute malnutrition in children in resource-limited settings
  UpToDate, 2018
- Trehan I, Manary MJ
  Management of complicated severe acute malnutrition in children in resource-limited settings
  UpToDate, 2017
- Trehan I, Manary MJ
  Management of uncomplicated severe acute malnutrition in children in resource-limited settings
  UpToDate, 2017
- Manary MJ, Trehan I
  Kwashiorkor
  BMJ Best Practice, 2016

Presentations

Presentation Title	Event	Location	Date
The unbearable lightness of being: Studies and stories of childhood malnutrition	43rd Annual Edward L. Pratt Lectures, Cincinnati Children’s Hospital Medical Center	Cincinnati, USA	May 2024
Anthropogenic climate change and infectious diseases	UW Symposium on Climate Change and Clinical Practice	Seattle, USA	March 2024
Immune function during and after SAM treatment	Action Against Hunger / USAID SAM Relapse Research Dissemination Event	Washington, USA	Dec. 2023
WHO wasting and nutritional oedema guidelines: Processes and lessons learned	2023 Action Against Hunger Research For Nutrition Conference	Paris, France	Nov. 2023
A frontline view of pediatric Ebola virus disease	National Emerging Special Pathogens Training and Education Center (NETEC) Global Rounds	Atlanta, USA	Aug. 2023
Protein in practice	USAID Specialized Food Aid Community of Practice 1st Annual Expanded Technical Meeting	Washington, USA	June 2023
A whirlwind tour of global malnutrition	Thriving Brains and Bodies: Nutrition From Conception Through Infancy, Oregon Health and Science University Center for Global Child Health Research Symposium	Portland, USA	April 2022
Childhood malnutrition: 2 case studies	Baylor College of Medicine and Texas Children's Hospital Foundations in Global Health	Houston, USA	April 2022
Childhood malnutrition: A whirlwind tour	St. Louis University Department of Pediatrics Grand Rounds	St. Louis, USA	Feb. 2022
Hot topics in infectious disease: Sexually transmitted infections in infants	Urgent Pediatric Problems: Bridging Office and Emergency Care	Seattle, USA	March 2021
Infections, immunity, and severe acute malnutrition	University of Washington Department of Epidemiology Seminar Series	Seattle, USA	Feb. 2021
Global child health	University of Hawai’i Department of Pediatrics Grand Rounds	Honolulu, USA	Nov. 2018
The unbearable lightness of being	Society for Pediatric Research Presidential Scientific Plenary, 2018 Pediatric Academic Societies Meeting	Toronto, Canada	May 2018
A clinician’s approach to childhood diarrhea in the developing world	68th Annual American Association for Clinical Chemistry Annual Scientific Meeting and Clinical Expo	Philadelphia, USA	Aug. 2016
Ethics in laboratory medicine: an Ebola perspective	American Society for Microbiology - Microbe 2016	Boston, USA	June 2016
Improving the understanding of childhood malnutrition in sub-Saharan Africa	University of Hawai’i Pacific Center for Emerging Infectious Diseases Research Seminar	Honolulu, USA	May 2016
A frontline view of Ebola	Washington University in St. Louis Department of Pediatrics Grand Rounds	St. Louis, USA	Dec. 2015
Recent evidence on improving the management of moderate acute malnutrition	MSF Canada 7th Annual Clinical Day	Montréal, Canada	June 2015
Some infectious thoughts on severe acute malnutrition	MSF Canada 7th Annual Clinical Day	Montréal, Canada	June 2015
Home-based therapy for severe acute malnutrition	9th St. Louis Children’s Hospital Perspectives in Pediatrics Conference	St. Louis, USA	May 2015
MD + MPH	Northwestern University 2015 MD/MPH Commencement	Chicago, USA	May 2015
Responding to emerging threats: Ebola outbreak management and preparedness	3rd Annual Washington University in St. Louis Global Health and Infectious Disease Conference	St. Louis, USA	April 2015
Legumes and growth	2014 Global Legume Innovation Lab Meeting	Athens, Greece	May 2014
Severe acute malnutrition	Section on International Child Health Program, American Academy of Pediatrics 2013 National Conference and Exhibition	Orlando, USA	Oct. 2013
Malnutrition, infection, and the microbiome: A new approach and a new horizon	The Lilliputian Surgical Society 53rd Annual Meeting	St. Louis, USA	Sept. 2013
A novel fortified blended flour, CSB++, is not inferior to lipid-based ready-to-use supplementary foods for the treatment of moderate acute malnutrition in Malawian children	International Food Aid Development Conference	Kansas City, USA	May 2012
Systematic review and GRADE summary of findings: The use of intravenous blood and/or plasma infusions in severe dehydration and shock	Third Nutrition Guidance Expert Advisory Group on Acute Malnutrition, Subgroup of Nutrition in the Life Course and Undernutrition, World Health Organization	Geneva, Switzerland	Feb. 2012
Systematic review and GRADE summary of findings: The management of diarrhea in community-based programs	Third Nutrition Guidance Expert Advisory Group on Acute Malnutrition, Subgroup of Nutrition in the Life Course and Undernutrition, World Health Organization	Geneva, Switzerland	Feb. 2012
Preliminary findings: Randomized, double-blind, placebo-controlled trial evaluating the need for routine antibiotics as part of the outpatient management of severe acute malnutrition	Third Nutrition Guidance Expert Advisory Group on Acute Malnutrition, Subgroup of Nutrition in the Life Course and Undernutrition, World Health Organization	Geneva, Switzerland	Feb. 2012
Systematic review and GRADE summary of findings: Care of HIV-infected children with severe acute malnutrition	Third Nutrition Guidance Expert Advisory Group on Acute Malnutrition, Subgroup of Nutrition in the Life Course and Undernutrition, World Health Organization	Geneva, Switzerland	Feb. 2012
Acute childhood malnutrition in resource-limited settings	CCHMC Global Health Speaker Series	Cincinnati, USA	April 2009

Research Funding

Grant Title	Grantor	Amount	Award Date
Accelerating National Wasting Treatment Reform in the Lao People’s Democratic Republic and Fiji	Eleanor Crook Foundation / Action Against Hunger UK	$15,000	2024 - 2025
Support for Development of Clinical Series on Growth Faltering and Wasting	Eleanor Crook Foundation	$100,000	2024 - 2025
Epidemiology, Biomarkers and Risk Stratification of Young Infants Presenting to the Emergency Department With Hypothermia	Gerber Foundation / Northwestern University	$5150	2023 - 2024
Immune Reconstitution After Anthropometric Recovery from Severe Acute Malnutrition	Children's Investment Fund Foundation	$249,395	2023 - 2025
Addressing Wasting and Stunting in Infants and Young Children by Increasing the Coverage and Quality of Selected High Impact Interventions in Ethiopia	UNICEF / Action Against Hunger USA	$266,192	2022 - 2024
Technical Expertise to Countries in the East Asia Pacific Region to Integrate Prevention and Treatment Services for Wasting into National Health Systems	UNICEF / Action Against Hunger UK	$40,000	2021 - 2023
Lactoferrin and Lysozyme to Promote Nutritional, Clinical, and Enteric Recovery: A Factorial Placebo-controlled Randomized Trial Among Children with Diarrhea and Malnutrition	Eunice Kennedy Shriver National Institute of Child Health and Human Development	$3,039,375	2021 - 2025
Novel Sensor and Biomarkers for Diagnosis of Malaria Using Human Breath	Bill and Melinda Gates Foundation	$1,000,000	2016 - 2017
Optimizing Therapeutic Foods for Neurocognitive Development in Malnourished Children	Children’s Discovery Institute of Washington University and St. Louis Children’s Hospital	$467,811	2016 - 2019
Legumes and Growth	USAID Feed the Future Innovation Lab for Collaborative Research on Grain Legumes	$3,000,000	2014 - 2017
Innovative Interventions for Improving Childhood Growth and Environmental Enteropathy	Children’s Discovery Institute of Washington University and St. Louis Children’s Hospital	$300,000	2014 - 2019
Towards Noninvasive Diagnosis of Malaria Infection Through Exhaled Breath Analysis	Children’s Discovery Institute of Washington University and St. Louis Children’s Hospital	$449,233	2014 - 2017
Understanding and Ameliorating Environmental Enteropathy	Children’s Discovery Institute of Washington University and St. Louis Children’s Hospital	$699,457	2013 - 2016

Overview

Board Certification(s): Pediatrics
Pediatric Emergency Medicine
Pediatric Infectious Diseases
Medical/Professional School: Northwestern University Feinberg School of Medicine, Chicago, IL
Universidad Peruana Cayetano Heredia, Lima, Peru
Residency: Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Fellowship: Washington University School of Medicine, Saint Louis, MO
Clinical Interests: diarrhea, emerging infectious diseases, fevers of unknown origin, HIV, malaria, malnutrition, neglected tropical diseases, parasitic infections, point-of-care ultrasound, respiratory distess, sepsis, shock, trauma, travel medicine, tuberculosis
Research Description: acute malnutriton, adaptation of medical technologies for low-resource settings, beriberi, environmental enteric dysfunction, novel diagnostics for tropical diseases, stunting, wasting
Research Focus Area: Global Health, Malnutrition, Medical Education, Tropical Medicine

Contact Information

Primary Office

Seattle Children's - Emergency Medicine 4800 Sand Point Way NE
MB.7.520
Seattle, WA 98105 Tel: 206-987-2599

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Indi Trehan, MD, MPH, DTM&H

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