Evelyn Kanyu Hsu, MD

"I love my job. It is a great honor and privilege to partner with patients and their families as they adjust to challenges of their diagnosis and see that hope and happiness can lie beyond their difficult journey. They, along with the amazing team I partner with here at Seattle Children's, are a daily inspiration. I believe that we can achieve the ideal outcome for every child and allow them to realize their life's dreams; this is what drives me forward in my both my clinical work and my research."

  • Biography

    Evelyn Hsu, MD joined the Division of Gastroenterology and Hepatology in 2011. She earned a medical doctorate degree with honors from the University of Wisconsin in 2003, following which she completed pediatric residency training at the University of Washington/Seattle Children's Hospital in 2006. 

    She went on to pursue further subspecialty fellowship training at the Children's Hospital of Philadelphia in Pediatric Gastroenterology, Hepatology and Nutrition and Pediatric Advanced/Transplant Hepatology. She is boarded in Pediatrics (2006), subspecialty boarded in Pediatric Gastroenterology (2011) and has additional certification in Pediatric Transplant Hepatology (2012).  She was the Transplant Hepatology Fellowship Program Director from 2014 to 2022, and Medical Director of the Liver Transplant Program from 2017 to 2022.

  • Patient Testimonials

  • Awards and Honors

    Award Name Award Description Awarded By Award Date
    SEATTLE TOP DOCTOR - 2022 Seattle Magazine 2022
    Seattle Top Doctor 2016 Seattle Met Magazine 2016
    SEATTLE'S TOP DOCTOR - 2015 Seattle Met Magazine 2015
    Outstanding Faculty Teaching Award University of Washington Pediatric Residency Program Jun 21, 2013
    Alpha Omega Alpha Honor Society University of Wisconsin Medical School 2003
    Waisman Award for Excellence in Pediatrics University of Wisconsin Medical School 2003
  • Publications

    Manuscripts Submitted

    • Hsu EK, Murray KF
      Cirrhosis and Chronic Liver Failure
      Liver Disease in Children, editors Suchy F, Sokol R, Balistereri W., 2014 : Chapter 6(Fourth edi)

    Other Publications

    • Weaver JJ, Dobrow EM, Hsu EK, Monroe EJ
      Single-access liver floss technique with antegrade hepatic vein access and recanalization in Budd-Chiari syndrome.
      29187341 Diagnostic and interventional radiology (Ankara, Turkey), 2017 Nov 30
    • Hsu EK, Shaffer ML, Gao L, Sonnenday C, Volk ML, Bucuvalas J, Lai JC
      Analysis of Liver Offers to Pediatric Candidates on the Transplant Wait List.
      28711630 Gastroenterology, 2017 Oct. : 153(4)988-995
    • Blondet NM, Healey PJ, Hsu E
      Immunosuppression in the pediatric transplant recipient.
      28964473 Seminars in pediatric surgery, 2017 Aug. : 26(4)193-198
    • Newton KP, Feldman HS, Chambers CD, Wilson L, Behling C, Clark JM, Molleston JP, Chalasani N, Sanyal AJ, Fishbein MH, Lavine JE, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN).
      Low and High Birth Weights Are Risk Factors for Nonalcoholic Fatty Liver Disease in Children.
      28366357 The Journal of pediatrics, 2017 Aug. : 187141-146.e1 PMCID:PMC5533631
    • Ebel NH, Hsu EK, Berry K, Horslen SP, Ioannou GN
      Disparities in Waitlist and Posttransplantation Outcomes in Liver Transplant Registrants and Recipients Aged 18 to 24 Years: Analysis of the UNOS Database.
      28230640 Transplantation, 2017 July : 101(7)1616-1627 PMCID:PMC5481466
    • Africa JA, Behling CA, Brunt EM, Zhang N, Luo Y, Wells A, Hou J, Belt PH, Kohil R, Lavine JE, Molleston JP, Newton KP, Whitington PF, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network.
      In Children With Nonalcoholic Fatty Liver Disease, Zone 1 Steatosis Is Associated With Advanced Fibrosis.
      28286193 Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2017 Mar 7 : PMCID:PMC5589478
    • Hsu EK, Mazariegos GV
      Global lessons in graft type and pediatric liver allocation: A path toward improving outcomes and eliminating wait-list mortality.
      27706890 Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2017 Jan. : 23(1)86-95
    • Schwimmer JB, Lavine JE, Wilson LA, Neuschwander-Tetri BA, Xanthakos SA, Kohli R, Barlow SE, Vos MB, Karpen SJ, Molleston JP, Whitington PF, Rosenthal P, Jain AK, Murray KF, Brunt EM, Kleiner DE, Van Natta ML, Clark JM, Tonascia J, Doo E, NASH CRN.
      In Children With Nonalcoholic Fatty Liver Disease, Cysteamine Bitartrate Delayed Release Improves Liver Enzymes but Does Not Reduce Disease Activity Scores.
      27569726 Gastroenterology, 2016 Dec. : 151(6)1141-1154.e9 PMCID:PMC5124386
    • Nelson JE, Handa P, Aouizerat B, Wilson L, Vemulakonda LA, Yeh MM, Kowdley KV, NASH Clinical Research Network.
      Increased parenchymal damage and steatohepatitis in Caucasian non-alcoholic fatty liver disease patients with common IL1B and IL6 polymorphisms.
      27730688 Alimentary pharmacology and therapeutics, 2016 Dec. : 44(11-12)1253-1264 PMCID:PMC5118184
    • Seo A, Walsh T, Lee MK, Ho PA, Hsu EK, Sidbury R, King MC, Shimamura A
      FAM111B Mutation Is Associated With Inherited Exocrine Pancreatic Dysfunction.
      26495788 Pancreas, 2016 July : 45(6)858-62 PMCID:PMC4841754
    • Wightman A, Hsu E, Zhao Q, Smith J
      Prevalence and Outcomes of Liver Transplantation in Children With Intellectual Disability.
      26655935 Journal of pediatric gastroenterology and nutrition, 2016 June : 62(6)808-12
    • Shneider BL, Magee JC, Karpen SJ, Rand EB, Narkewicz MR, Bass LM, Schwarz K, Whitington PF, Bezerra JA, Kerkar N, Haber B, Rosenthal P, Turmelle YP, Molleston JP, Murray KF, Ng VL, Wang KS, Romero R, Squires RH, Arnon R, Sherker AH, Moore J, Ye W, Sokol RJ, Childhood Liver Disease Research Network (ChiLDReN).
      Total Serum Bilirubin within 3 Months of Hepatoportoenterostomy Predicts Short-Term Outcomes in Biliary Atresia.
      26725209 The Journal of pediatrics, 2016 March : 170211-7.e1-2 PMCID:PMC4826612
    • Shen TC, Chehoud C, Ni J, Hsu E, Chen YY, Bailey A, Laughlin A, Bittinger K, Bushman FD, Wu GD
      Dietary Regulation of the Gut Microbiota Engineered by a Minimal Defined Bacterial Consortium.
      27176607 PloS one, 2016 : 11(5)e0155620 PMCID:PMC4866709
    • Hsu E, Horslen S
      The emergence of eosinophilic disorders in pediatric transplant recipients.
      24164823 Pediatric transplantation, 2013 Dec. : 17(8)713-5
    • Hsu EK, Chugh P, Kronman MP, Markowitz JE, Piccoli DA, Mamula P
      Incidence of perforation in pediatric GI endoscopy and colonoscopy: an 11-year experience.
      23433599 Gastrointestinal endoscopy, 2013 June : 77(6)960-6
    • Hsu EK
      Schwartz's Clinical Handbook of Pediatrics, 2013 : 5th editio(Chapter 45)
    • Hsu EK, Reyes JD
      Pediatric Liver Transplantation
      Diseases of the Liver in Children: Evaluation and Management, editors Murray KF and Horslen SP., 2013
    • Hsu EK
      Schwartz's Clinical Handbook of Pediatrics, 2013 : 5th editio(Chapter 14)
    • Hsu E, Murray K
      Is nonalcoholic fatty liver disease in children the same disease as in adults?
      22824482 Clinics in liver disease, 2012 Aug. : 16(3)587-98
    • Evelyn Kanyu Hsu, MD, Hsu EK, Mamula P, Ruchelli ED
      Intestinal Polyposis Syndromes
      eMedicine from WebMD, 2011 Jan 3 : http://emedicine.medscape.com/article/929144-overv
    • Evelyn Kanyu Hsu, MD, Javid PJ, Malone FR, Dick AA, Hsu E, Sunseri M, Healey P, Horslen SP
      A contemporary analysis of parenteral nutrition-associated liver disease in surgical infants
      Journal of Pediatric Surgery, 2011 : 46: 1913-1917
    • Evelyn Kanyu Hsu, MD, Hsu EK, Wu GD.
      Gut Microbes, Immunity and Metabolism
      Metabolic Basis of Obesity; Editor, Ahima R. Springer, New York, 2011 : 311-350
    • Evelyn Kanyu Hsu, MD, Mascarenhas M, Hsu EK
      Treatment of gastrointestinal complications of Cystic Fibrosis
      US Respiratory Reviews, 2008
    • Evelyn Kanyu Hsu, MD, Hsu EK, Murray KF
      Hepatitis B and C in children
      Nat Clin Pract Gastroenterol Hepatol, 2008 : 5(6): 311-320
    • Evelyn Kanyu Hsu, MD, Hsu EK, Murray KF
      Hepatitis C in Children
      J Pediatr Infect Dis, 2007 : (1): 3-9
  • Presentations

    Presentation Title Event Location Date
    Common Problems in Pediatric Gastroenterology Pediatric Grand Rounds, The Everett Clinic Everett, Washington Sep 27, 2011
    Pediatric Mortality on the Liver Transplant Wait List: A Single-Center 15 year Experience (poster presentation) AASLD Single Topic Conference: Pediatric Transplantation Atlanta, GA Mar 18, 2011
    Oral Antibiotics Reverse Maladaptive Metabolic Responses to a Low Protein Diet (poster presentation) Digestive Diseases Week New Orleans, LA May 4, 2010
    Innate and Adaptive Immunity Regulate Metabolic Responses to Parasitic Nematode Infection (poster presentation) Digestive Diseases Week Chicago, IL May 2, 2009
    Innate and Adaptive Immunity Regulate Metabolic Responses to Parasitic Nematode Infection (poster presentation) CHOP Fellows Research Day Feb 25, 2009


Board Certification(s)

Pediatric Gastroenterology
Pediatric Transplant Hepatology

Medical/Professional School

University of Wisconsin School of Medicine & Public Health, Madison, WI


University of Washington School of Medicine, Seattle, WA


Children's Hospital of Philadelphia, Philadelphia, PA

Clinical Interests

Pediatric liver and small-intestine transplant, childhood cholestasis, autoimmune liver disease, viral hepatitis. Long-term outcomes for pediatric liver transplant recipients, Childhood cholestatic liver disease