Current Research Studies

PNOC028: Phase 1 Study of Intra-Tumoral Injections of Ex Vivo Expanded Natural Killer Cells in Children and Young Adults with Recurrent or Progressive Supratentorial Malignant Brain Tumors

PNOC028

  • Condition(s): Brain and Nervous System
  • Phase: I
  • Clinicaltrials.gov ID: NCT05887882

What is the goal of the study?

The purpose of this study is to see if it is safe and feasible to treat brain tumors with donor natural killer (NK) cells. The cells will be administered directly into the tumor or the resection area using a device called an Ommaya reservoir. We want to find out what effects, good or bad, this has on patients and their tumors.

Who can participate in the study?

Progressive or recurrent malignant brain tumor.

Study Team: