Erin E. Crotty, MD

Erin E. Crotty, MD

Brain Tumor Program

On staff since July 2020

  • Erin Crotty, M.D. is an Attending Physician at Seattle Children's Hospital and Acting Instructor at the University of Washington School of Medicine. She cares for children and adolescents with brain and spinal cord tumors, in addition to leading the Retinoblastoma Program with oncologic ophthalmologist, Dr. Andrew Stacey. Dr. Crotty completed her pediatric residency training at Children's National Medical Center in Washington, D.C. and returned home to the west coast for fellowship in hematology/oncology at Seattle Children's Hospital/University of Washington. She holds board certifications in pediatrics and pediatric hematology/oncology.

    Dr. Crotty joined the Olson Laboratory at the Fred Hutchinson Cancer Research Center as a post-doctoral researcher with an interest in studying novel immunotherapies for children with central nervous system tumors. Under the mentorship of Jim Olson, MD, PhD, her research in immunomodulator strategies to target medulloblasotma has received grant funding from the Childhood Brain Tumor Foundation, generous philanthropic support, and provided the preclinical basis for an upcoming consortium-led Phase I clinical trial. Of particular interest to Dr. Crotty is the translation of new strategies from the lab bench to the patient for difficult to treat brain tumors, including medulloblastoma, DIPG, high-grade glioma, and ependymoma.  

    • Related Pages

    • The Olson Lab

      The Olson lab identifies, prioritizes, and advances therapeutics into clinical trials for children with brain cancer, with increasing focus on types of brain tumors that are uncommon and have the greatest need for translational research.

    • Emma Seattle 03.30.21

      Dr. Crotty is an incredible doctor who treats not only our son, but our entire family, with the utmost care and respect. She became our primary oncologist shortly after joining Seattle Children's brain tumor team and I could not believe we got so lucky to be connected with her when our son was diagnosed with brain cancer. She has helped us navigate the most difficult conversations and decisions with expert information, thorough explanation, and so much compassion. I couldn't recommend Dr. Crotty more for her expertise and caring nature.

  • Award Name Award Description Awarded By Award Date
    Clinical Scholars Research Program Seattle Children's Research Institute Oct. 2021 - Oct. 2023
    Resident Teaching Award Children's National Medial Center 2015 - 2017
    Gill Fellowship Research Award George Washington University 2011
  • Other Publications

    • Crotty EE, Smith SMC, Brasel K, Pakiam F, Girard EJ, Connor YD, Zindy F, Mhyre AJ, Roussel MF, Olson JM
      Medulloblastoma recurrence and metastatic spread are independent of colony-stimulating factor 1 receptor signaling and macrophage survival.
      33963961 Journal of neuro-oncology, 2021 June : 153(2)225-237 PMCID:PMC8248272
    • Crotty EE, Smith SMC, Brasel K, Pakiam F, Girard EJ, Connor YD, Zindy F, Mhyre AJ, Roussel MF, Olson JM
      Medulloblastoma recurrence and metastatic spread are independent of colony-stimulating factor 1 receptor signaling and macrophage survival.
      33963961 Journal of neuro-oncology, 2021 June : 153(2)225-237 PMCID:PMC8248272
    • Crotty E, Downey K, Ferrerosa L, Flores C, Hegde B, Raskin S, Hwang E, Vitanza N, Okada H
      Considerations when treating high-grade pediatric glioma patients with immunotherapy.
      33225764 Expert review of neurotherapeutics, 2020 Dec. 17 : 1-15
    • Crotty EE, Leary SES, Geyer JR, Olson JM, Millard NE, Sato AA, Ermoian RP, Cole BL, Lockwood CM, Paulson VA, Browd SR, Ellenbogen RG, Hauptman JS, Lee A, Ojemann JG, Vitanza NA
      Children with DIPG and high-grade glioma treated with temozolomide, irinotecan, and bevacizumab: the Seattle Children's Hospital experience.
      32556862 Journal of neuro-oncology, 2020 July : 148(3)607-617
    • Crumm CE, Crotty EE, Albert CM, Blair AB, Otjen JP, Feldman KW
      Atraumatic Spinal Epidural Hematoma as Initial Presentation of Hemophilia A in an Infant.
      30870339 Pediatric emergency care, 2019 March 12
    • Crotty EE, Meier ER, Wells EM, Hwang EI, Packer RJ
      Anaplastic Ependymoma in a Child With Sickle Cell Anemia: A Case Report Highlighting Treatment Challenges for Young Children With Central Nervous System Tumors and Underlying Vasculopathy.
      26488903 Pediatric blood & cancer, 2016 March : 63(3)547-50

  • Grant Title Grantor Amount Award Date
    Clinical Research Scholars Program (CRSP) Award Center for Clinical and Translational Research Oct. 2021 - Oct. 2023
    The Childhood Brain Tumor Foundation Research Grant The Childhood Brain Tumor Foundation July 2020 - July 2022
    NIH 5T32CA009351 Ruth L. Kirschstein Research Service Award NIH July 2018 - July 2020

Overview

Board Certification(s)

Pediatrics

Medical/Professional School

George Washington University School of Medicine and Health Sciences, Washington

Residency

Pediatrics, Children's National Medical Center, Washington

Fellowship

Pediatric Hematology Oncology, University of Washington School of Medicine, Seattle

Research Description

Dr. Crotty partners with investigators at the Fred Hutchinson Cancer Research Center, Seattle Children's Research Institute, and consortium members across multi-national institutions to develop clinical research protocols and translate basic science discoveries into promising therapies. Her upcoming Clinical Scholar Research Award will support the development of a Phase I clinical trial investigating a combinatorial immunotherapy approach for children and adolescents with relapsed/refractory brain tumors, such as DIPG, high-grade glioma, and atypical teratoid rhabdoid tumor (AT/RT). 

Research Focus Area

Brain tumor, Immunotherapy, CAR-T cells