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Current Research Studies

Kids MoD PAH Trial: Mono- vs. Duo-Therapy for Pediatric Pulmonary Arterial Hypertension

Kids MoD PAH

Condition: Cardiology
Phase: III
Clinicaltrials.gov ID: NCT04039464

What is the goal of the study?

In this study, we will compare the safety and efficacy of two treatment strategies in pediatric subjects with a new diagnosis of Pulmonary Arterial Hypertension: 1) first-line combination therapy (sildenafil and bosentan); versus 2) first-line monotherapy (sildenafil alone). Efficacy will be assessed by WHO functional class (FC) at twelve months after initiation of study drug therapy.

Who can participate in the study?

Please contact the study team listed below to learn more.

Study Team:

PI (Study Doctor): Delphine Yung
Study Team Member: Erin Anthony-Fick, Erin.Anthony-Fick@seattlechildrens.org

Seattle Children’s complies with applicable federal and other civil rights laws and does not discriminate, exclude people or treat them differently based on race, color, religion (creed), sex, gender identity or expression, sexual orientation, national origin (ancestry), age, disability, or any other status protected by applicable federal, state or local law. Financial assistance for medically necessary services is based on family income and hospital resources and is provided to children under age 21 whose primary residence is in Washington, Alaska, Montana or Idaho.