Heart center protocol for collecting and banking DNA to determine genetic basis for Kawasaki Disease and-MIS-C or COVID
Kawasaki Disease and MIS-C
What is the goal of the study?
The researchers would like to collect blood and/or buccal samples from pediatric patients with Kawasaki Disease and their parents and siblings. They would also like to create a repository for these specimens for future research on the genetic basis of Kawasaki Disease and other heart diseases. The samples will be used initially to test a specific hypothesis that, by using improved and rigorous phenotyping techniques in combination with whole genome sequencing (WGS) and analyses, we will be able to identify select biomarkers for accurate prediction of KD treatment response and development of coronary aneurysms. Upon successful identification of biomarkers and polymorphisms that determine susceptibility in these KD patients, we will develop options for further investigation and intervention, and the researchers will retain specimens for future genetic research on the basis and treatment of KD. Patients will be asked to donate blood or saliva and provide information about their ethnic background. No other procedures will be done for this research study. The subject’s participation will end once the blood or saliva has been donated.
Who can participate in the study?
Please contact the study team listed below to learn more.