Comparing Two Durations of Antibiotic Treatment for Children Hospitalized for fewer than 5 days with Common Infections
TRIAD
What is the goal of the study?
TRIAD is a multicenter, double-blinded, placebo-controlled trial to compare short versus long antibiotic duration (1:1 allocation).The research intervention will be 5-days vs. 10-days of antibiotics and study population will be Children: 1) discharged from pediatric hospital medicine services; 2) treated for pneumonia, skin and soft tissue infection, or urinary tract infection, and 3) prescribed on one of the study formulary antibiotics The primary objective of this study is to Determine if short duration antibiotic treatment (5 days total) is superior to long duration treatment (10 days total) in children hospitalized with common bacterial infections (pneumonia, SSTI, UTI). The secondary objective is to determine condition-specific and subgroup effects of short versus long duration treatment. The third objective will utilize qualitative methods to understand participant experiences with the recruitment and trial processes.
Who can participate in the study?
Please contact the study team listed below to learn more.