Current Research Studies

APEC1621F: Pediatric MATCH (Molecular Analysis for Therapy Choice)

APEC1621F_Ensarti

  • Condition(s): Adrenal Tumors, Adrenocortical Carcinoma, Anaplastic Large Cell Lymphoma (ALCL), Atypical Teratoid/Rhabdoid Tumor, Brain Tumor, Burkitt's Lymphoma, CNS Embryonal Tumors, CNS Germ Cell Tumors, CNS Sarcoma, Choroid Plexus Tumors, Clear Cell Sarcoma of the Kidney, Craniopharyngioma, Diffuse Intrinsic Pontine Glioma (DIPG), Diffuse Large B-cell Lymphoma (DLBCL), Diffuse Midline Glioma (DMG), Ependymoma, Ewing Sarcoma, Germ Cell Tumors, Glioneuronal and Neuronal Tumors, Hepatoblastoma, Hepatocellular Carcinoma, High-Grade Glioma, Histiocytic Tumors, Juvenile Xanthogranuloma (JXG), Langerhans Cell Histiocytosis (LCH), Leukemia & Lymphoma, Liver Tumors, Low-Grade Glioma, Lymphoblastic Lymphoma (LBL), Malignant Bone Tumors, Medulloblastoma, Neuroblastoma, Non-Hodgkin Lymphoma (NHL), Non-rhabdomyosarcoma Soft Tissue Sarcomas, Osteosarcoma, Pheochromocytoma, Pilocytic Astrocytoma, Recurrent and/or Refractory, Renal Cell Carcinoma, Renal Tumors, Retinoblastoma, Rhabdoid Tumor of the Kidney, Rhabdomyosarcoma, Soft Tissue Sarcomas, Solid Tumor, Thyroid Cancer, Wilms Tumor
  • Phase: II
  • Clinicaltrials.gov ID: NCT03213652

What is the goal of the study?

The goal of this study is to see how well genetically targeted medication works on patients with specific genetic mutations, specifically in patients with solid tumors, non-Hodgkin lymphomas and histiocytic disorders. This study will also look at patients' progress after treatment and how well patients tolerate the study's drug. This study is one of many studies that are focused on treating cancer using genomics.

Who can participate in the study?

This study may be a good fit for children and young adults who are: - Enrolled in study APEC1621SC - Between 12 months and 21 years old You can read more about the eligibility criteria for this study on clinicaltrials.gov. Researchers use many other factors to decide whether a patient can take part in a study (inclusion criteria) or cannot take part (exclusion criteria). The study team at Seattle Children’s can explain what these factors mean for your child.

Study Team: