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Current Research Studies

Clincial Trials Search

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- Abdominal Pain – Sleep Pain And Cardiac Evaluation-XL (SPACE-XL)
- ADHD – Treating Parents with ADHD and Their Children (TPAC)
- Asthma – Airway Epithelial Cell Cytokine Profiles of Children With and Without Asthma Study
- Asthma – Role of the Airway Epithelium in Children with Asthma
- Attention – Development and Attention In a Study of Young children (DAISY)
- Autism - CHART Study - Congenital Cytomegalovirus, Hearing Loss, and Autism Retrospective Study
- Autism – Generating Effectiveness Mechanisms in RUBI (GEMs in RUBI)
- Autism – SPARK: Simons Foundation Powering Autism Research for Knowledge Study
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- Cancer – A Phase 2 Study Evaluating Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors for Prevention of GVHD
- Cancer – AALL1731: A Study to Investigate Blinatumomab in Combination with Chemotherapy in Patients with Newly Diagnosed B-Lymphoblastic Leukemia
- Cancer – AALL1732: A Phase 2 Randomized Trial of Inotuzumab Ozogamicin for Newly Diagnosed High-Risk B-ALL; Risk-Adapted Post-Induction Therapy for High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and Disseminated B-LLy
- Cancer – AALL1931: An Open-Label, Multicenter Study of RC-P in Patients with Acute Lymphoblastic Leukemia (ALL)/Lymphoblastic Lymphoma (LBL) Following Hypersensitivity to E. coli-derived Asparaginases
- Cancer – ADVL1823: Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia
- Cancer – AGCT1532: Phase 3 Accelerated BEP Trial: A Ramdomized Phase 3 Trial of Accelerated vs. Standard BEP Chemotherapy for Patients with Intermediate and Poor-Risk Metastatic Germ Cell Tumors
- Cancer – ANBL1232: Utilizing Response - and Biology-Based Risk Factors to Guide Therapy in Patients with Non-High-Risk Neuroblastoma - a Groupwide Historically Controlled Phase 3 Study
- Cancer – ARST1431: Combination Chemotherapy With or Without Temsirolimus in Treating Patients with Intermediate Risk Rhabdomyosarcoma
- Cancer – BrainChild-01: CAR T-Cell Therapy for Brain and Central Nervous System Tumors Clinical Trial
- Cancer – BrainChild-02: Phase 1 Study of EGFR806-Specific CAR T-Cell Locoregional Immunotherapy for EGFR-Positive Recurrent or Refractory Pediatric Central Nervous System Tumors
- Cancer – BrainChild-03: Phase 1 Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors
- Cancer – ENLIGHTen-01: A Phase I Feasibility And Safety Study of Fluorescein-Specific (FITC-E2) CAR T Cells In Combination With Parenterally Administered Folate-Fluorescein (UB-TT170) For Osteogenic Sarcoma
- Cancer – H-42691: A Trial of Atovaquone (MEPRON) Combined with Conventional Chemotherapy for De Novo Acute Myeloid Leukemia (AML) in Children, Adolescents and Young Adults
- Cancer – HA-1 TCR: T-Cell Immunotherapy for Treating Patients with Relapsed or Refractory Acute Leukemia after Donor Stem Cell Transplant Clinical Trial
- Cancer – NCT03971799: Phase 1/2 Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and Young Adults with Relapsed/Refractory Acute Myeloid Leukemia
- Cancer – PBTC-042: Phase I Study of CDK 4-6 Inhibitor PD-0332991 In Children With Recurrent, Progressive or Refractory Central Nervous System Tumors
- Cancer – PEPN1812: A Phase 1 Trial of the CD123 X CD3 Dual Affinity Re-Targeting Antibody Flotetuzumab in Children, Adolescents, and Young Adults with Relapsed or Refractory Acute Myeloid Leukemia
- Cancer – PLAT-05: A Phase 1 Feasibility and Safety Study of Dual Specificity CD19 and CD22 CAR T-cell Immunotherapy for CD19+CD22+ Leukemia and Lymphoma
- Cancer – PLAT-07: A Phase 1/2 Study of CD22-Specific CAR T Cells for CD22+ Leukemia or Lymphoma
- Cancer – PLAT-08: A Phase 1 Study of SC-DARIC33 in Children and Young Adults with Relapsed or Refractory CD33+ AML
- Cancer – PNOC-013: REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma
- Cancer – S1826: Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma
- Cancer – SC-4016: Phase 1 and 2 Study of LOXO-195 in Patients With Previously Treated NTRK Fusion Cancers
- Cancer – SC-9012: Phase I-II Study of MEK 162 for Children with Low-Grade Gliomas and Other Ras/Raf/ERK Pathway Activated Tumors
- Cancer – SC-9015: ONC201 in Newly Diagnosed Diffuse Intrinsic Pontine Glioma and Recurrent/Refractory Pediatric H3K27M Gliomas
- Cancer – STRIvE-01: Phase I Study of EGFR806 CAR T Cell Immunotherapy for Relapsed or Refractory Solid Tumors in Children and Young Adults
- Cancer – STRIvE-02: A Phase 1 Study of B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
- Cancer – STUDY00000880: The Pediatric MATCH Screening Trial
- Cancer – STUDY00002718: A Study to Evaluate the Safety and Efficacy of JCAR017 in Pediatric Subjects With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Non-Hodgkin Lymphoma
- Cancer – T2016-002:A Phase I/II Study of Nivolumab in Combination with 5-azacytidine in Pediatric Patients with Relapsed/Refractory Acute Myeloid Leukemia
- CDG – Clinical and Basic Investigations into Phosphomannomutase Deficiency (PMM2-CDG1a)
- Cerebral Palsy – Power Training Combined with Interval Treadmill Training to Improve Walking Activity in Cerebral Palsy (PT3)
- Cerebral Palsy – Short Burst Locomotor Treadmill Training Study
- Cleft Lip and Palate – A Retrospective Study of Breast Milk Feeding Children with Oral Clefts
- Cleft Lip and Palate – Clinical Effectiveness of Late Maxillary Protraction in Cleft Lip and Palate Study
- Cleft Lip and Palate – Infants with Orofacial Clefts: Development and Validation of an Observer-Reported Outcomes Instrument (ICOO)
- Concussion - Four Corners Youth Concussion Registry
- Concussion – Collaborative Care Model for Treatment of Persistent Symptoms After Concussion Among Youth (Collaborative Care Study)
- Concussion – Mobile Sub-threshold Exercise Program for Concussion (M-STEP)
- Conmoción cerebral – Programa de ejercicio móvil subumbral para la conmoción cerebral
- COVID-19 - Pfizer Bivalent Vaccine Study
- Craniofacial Microsomia – Accelerating Research and Education (CARE) Study
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- Diabetes: TrialNet T1D Risk Screening Pathway to Prevention
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- Epilepsy – An Open-Label Study with Extension Phase to Evaluate the Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Subjects (Age 1 Month to Less Than 18 Years) With Childhood Epilepsy
- Epilepsy – Molecular Genetic Studies on Developmental Disorders
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- Gene Transfer for X-Linked Severe Combined Immunodeficiency in Newly Diagnosed Infants (LVXSCID-ND)
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- Headache and Migraine – A Randomized, Double-Blind, Placebo-Controlled Study of Galcanezumab in Adolescent Patients 12 to 17 Years of Age with Chronic Migraine – the REBUILD-2 Study
- Headache and Migraine – A Randomized, Double-Blind, Placebo-Controlled Study of Galcanezumab in Patients 6 to 17 Years of Age with Episodic Migraine – the REBUILD-1 Study
- Headache and Migraine – Pediatric Options for Migraine Relief: A Randomized, Double-Blind, Placebo-Controlled Study of Lasmiditan for Acute Treatment of Migraine: PIONEER-PEDS1
- Hearing – The Development of Sensitivity to Electrical Stimulation with Cochlear Implants Study
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- Immunology – Immunology Biorepository Study
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- Kidney Disease – Nephrotic Syndrome Study Network, 2nd cohort (cNEPTUNE)
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- Lysosomal Storage Disease Registries – Fabry, Pompe, Gaucher and MPS1
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- Mucopolysaccharidosis Type IVA – Morquio A Registry Study (MARS)
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- Obesity – Brain Activation and Satiety In Children 2
- Orthopedics - Bracing vs. Casting in the Treatment of Idiopathic Early-Onset Scoliosis
- Orthopedics - Clinical Depression Among Adolescent Patients After Orthopedic and Sports Medicine Treatment
- Orthopedics - Compliance in a Yoga-Based Postoperative Rehabilitation Protocol for Adolescent Idiopathic Scoliosis: A Pilot Study
- Orthopedics - Elucidating the Discoid Meniscus with Proposed New Classification System
- Orthopedics - Fox Pediatric Congenital Spinal Deformity Study
- Orthopedics - HARMS Study Group: Idiopathic Scoliosis Outcomes Database Registry
- Orthopedics - HARMS Study Group: Prospective Database Registry Study of Scoliosis in Children with Cerebral Palsy
- Orthopedics - Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease
- Orthopedics - Non-Fusion Spinal Deformity Correction in Idiopathic Scoliosis: A Prospective Database Registry Study of the HARMS Study Group
- Orthopedics - Pediatric Tibial Spine Fractures Prospective Cohort
- Orthopedics - The Chest Wall and Spine Deformity Registry
- Orthopedics – Does a Pre-Operative Carbohydrate Drink Decrease Time For Gastrointestinal Function To Return After Spinal Fusion Surgery?
- Orthopedics – Registries for Children with Congenital Upper Limb Differences
- Orthopedics, ACL – Clinical Outcomes and Physical Therapy Functional Assessments in Pediatric and Adolescent Patients After ACL Reconstruction Study
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- Pancreatitis – WebMAP Chronic Pancreatitis
- Parents Perceptions of Engagement in Telehealth and In-Person Services (PPE TIPS)
- Preschoolers Learning and Active in Play (PLAY) Study
- Psychiatry and Behavioral Medicine – The INCLUDE Developmental Delay Study
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- Rheumatic Diseases: Observational Study of Pediatric Rheumatic Diseases - The CARRA Registry
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- Seizure – Pediatric Dose Optimization for Seizures in Emergency Medical Services
- Sepsis – Pragmatic Pediatric Trial of Balanced vs NormaL Saline Fluid in Sepsis (PRoMPT BOLUS)
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- Tourette Disorder - Collaborative Genomic Studies of Tourette Disorder
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- Undiagnosed Diseases Network – Pacific Northwest
- Urea Cycle Disorders – Longitudinal Study
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- Vaccines: New Vaccine Surveillance Network (NVSN) - Healthy Control
- Vascular Anomalies – Lymphatic Malformation Quality of Life Study
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- Weight Management – Success in Health, Impacting Families Together (SHIFT) Study

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