Current Research Studies

Clincial Trials Search

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- Acidemia – Mapping the Patient Journey in Methylmalonic and Propionic Acidemia (The MaP Study)
- ADHD – Lifestyle Enhancement for ADHD Program (LEAP)
- ADHD – The Effects of ADHD Medicine (TEAM) Study
- Asthma – Airway Epithelial Cell Cytokine Profiles of Children With and Without Asthma Study
- Autism Spectrum Disorder: Washington Study of Outcomes, Neural Development, and Early Risk (WONDER)
- Autism – SPARK: Simons Foundation Powering Autism Research for Knowledge Study
- Autism – The Autism Biomarkers Consortium Clinical Trials
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- Bone Marrow Transplant – Prevention of Bone Loss after Pediatric Hematopoietic Cell Transplantation
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- Cancer - AALL15P1: A Groupwide Pilot Study to Test the Tolerability and Biologic Activity of the Addition of Azacitidine to Chemotherapy in Infants with Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement
- Cancer - ACNS02B3: A Children's Oncology Group Protocol for Collecting and Banking Pediatric Brain Tumor Research Specimen
- Cancer - AHODO831: A Non-Randomized Phase III Study of Response Adapted Therapy for the Treatment of Children with Newly Diagnosed High Risk Hodgkin Lymphoma
- Cancer - ANBL1821: Phase 2 Randomized Study of Irinotecan/Temozoloide/Dinutuximab with or without Eflornithine in Children with Relapsed, Refractory or Progressive Neuroblastoma
- Cancer – A Phase 2 Study Evaluating Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors for Prevention of GVHD
- Cancer – ACNS0831: Phase 3 Randomized Trial of Post-Radiation Chemotherapy in Patients with Newly Diagnosed Ependymoma Ages 1 to 21 Years
- Cancer – ACNS1422: Phase 2 Study of Reduced Therapy for Newly Diagnosed Average-Risk WNT-Driven Medulloblastoma Patients
- Cancer – BrainChild-01: CAR T-Cell Therapy for Brain and Central Nervous System Tumors Clinical Trial
- Cancer – BrainChild-02: Phase 1 Study of EGFR806-Specific CAR T-Cell Locoregional Immunotherapy for EGFR-Positive Recurrent or Refractory Pediatric Central Nervous System Tumors
- Cancer – ENCIT-01: Engineered Neuroblastoma Cellular Immunotherapy
- Cancer – HA-1 TCR T-Cell Immunotherapy for Treating Patients with Relapsed or Refractory Acute Leukemia after Donor Stem Cell Transplant Clinical Trial
- Cancer – PBTC-042: Phase I Study of CDK 4-6 Inhibitor PD-0332991 In Children With Recurrent, Progressive or Refractory Central Nervous System Tumors
- Cancer – PLAT-02: A Phase 1/2 Feasibility and Safety Study of CD19-CAR T-Cell Immunotherapy for CD19+ Leukemia
- Cancer – PLAT-03: A Pilot Feasibility and Safety Study of CD19t T-APC Vaccination Following CAR T-Cell Immunotherapy for CD19+ Leukemia
- Cancer – PLAT-04: A Phase 1 Feasibility and Safety Study of CD22 CAR T-Cell Immunotherapy for CD22+ Leukemia
- Cancer – PLAT-05: A Phase 1 Feasibility and Safety Study of Dual Specificity CD19 and CD22-CAR T-Cell Immunotherapy for CD19+CD22+ Leukemia and Lymphoma
- Cancer – PLAT-06: A Phase 1/2 Study of CD19-specific CAR T Cells With a Fully Human Binding Domain for CD19+ Leukemia or Lymphoma
- Cancer – PNOC012: A Randomized, Blinded Study of Fluorescence Detection of Pediatric Primary Central Nervous System Tumors in Subjects Receiving Tozuleristide and Imaged With the Canvas System
- Cancer – SC-4016: Phase 1 and 2 Study of LOXO-195 in Patients With Previously Treated NTRK Fusion Cancers
- Cancer – SC-9010: Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors (SJATRT)
- Cancer – SC-9012: Phase I-II Study of MEK 162 for Children with Low-Grade Gliomas and Other Ras/Raf/ERK Pathway Activated Tumors
- Cancer – STRIvE-01: Phase I Study of EGFR806 CAR T Cell Immunotherapy for Relapsed or Refractory Solid Tumors in Children and Young Adults
- CDG – Clinical and Basic Investigations into Phosphomannomutase Deficiency (PMM2-CDG1a)
- Cerebral Palsy - Short Burst Locomotor Treadmill Training Study
- Cerebral Palsy – Biomechanics and Walking in Cerebral Palsy: Ankle Foot Orthoses Footwear Combinations Study
- Cerebral Palsy – Power Training Combined with Interval Treadmill Training to Improve Walking Activity in Cerebral Palsy (PT3)
- Cleft Lip and Palate – A Retrospective Study of Breast Milk Feeding Children with Oral Clefts
- Cleft Lip and Palate – Clinical Effectiveness of Late Maxillary Protraction in Cleft Lip and Palate Study
- Cleft Lip and Palate – Infants with Orofacial Clefts: Development and Validation of an Observer-Reported Outcomes Instrument (ICOO)
- Concussion – Collaborative Care Model for Treatment of Persistent Symptoms After Concussion Among Youth (Collaborative Care Study)
- Cystic Fibrosis – STOP-PEDS Feasibility: Standardizing Treatment of Pulmonary Exacerbations in Pediatrics Pilot Feasibility Study
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- Diabetes – SEARCH for Diabetes in Youth Study
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- Gastroenterology – The Healthy Endoscopy Research Study
- Gene Transfer for X-Linked Severe Combined Immunodeficiency in Newly Diagnosed Infants (LVXSCID-ND)
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- Headache and Migraine – Headache Screening Study
- Hearing – The Development of Sensitivity to Electrical Stimulation with Cochlear Implants Study
- High Blood Pressure – Adult Hypertension Onset in Youth (SHIP AHOY) Study
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- IBS - iSTEP Study for Mothers with IBS
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- Kidney Disease – Nephrotic Syndrome Study Network, 2nd cohort (cNEPTUNE)
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- Lysosomal Storage Disease Registries – Fabry, Pompe, Gaucher and MPS1
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- Mucopolysaccharidosis Type IVA – Morquio A Registry Study (MARS)
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- Orthopedics – Lung Function in Children With Early Onset Scoliosis: Effect of Body Position Study
- Orthopedics – Muscle Strength and Functional Performance After Medial Patellofemoral Ligament Reconstruction
- Orthopedics – Non-Operative Treatment Compared With Internal Fixation for Displaced Medial Humeral Epicondyle Fractures: A Multicenter Prospective Evaluation
- Orthopedics – Registries for Children with Congenital Upper Limb Differences
- Orthopedics – Registry of Children With Acquired and Congenital Limb Deficiencies
- Orthopedics – Skeletal Dysplasia Clinical Registry
- Orthopedics – Spine and Chest Wall Deformity Registries
- Orthopedics, ACL – Clinical Outcomes and Physical Therapy Functional Assessments in Pediatric and Adolescent Patients After ACL Reconstruction Study
- Orthopedics, ACL – Quadriceps Tendon Autograft Anterior Cruciate Ligament Reconstruction With Suture Tape Reinforcement: A Randomized Controlled Trial
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- Pain – Maternal Chronic Pain Study
- PREDICT Trial: Precision Diagnostics in Inflammatory Bowel Disease, Cellular Therapy and Transplantation
- Preschoolers Learning and Active in Play (PLAY) Study
- Psychiatry and Behavioral Medicine – The INCLUDE Developmental Delay Study
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- Sleep – Sleep and Ecological Factors in Infants with Craniofacial Conditions (ECOSleep) Study
- Sleep – Sleep Health in Preschoolers (SHIP)
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- Tuberous Sclerosis Complex - Preventing Epilepsy Using Vigabatrin in Infants with Tuberous Sclerosis Complex (PREVeNT Trial)
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- Urea Cycle Disorders – Longitudinal Study
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- Weight Management – Energy Balance and Weight Loss in Craniopharyngioma-related Hypothalamic Obesity (ECHO)
- Weight Management – Success in Health, Impacting Families Together (SHIFT) Study

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