Current Research Studies

APEC14B1

APEC14B1

  • Condition(s): Acute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), Adrenal Tumors, Adrenocortical Carcinoma, Anaplastic Large Cell Lymphoma (ALCL), Atypical Teratoid/Rhabdoid Tumor, Biology, Brain Tumor, Burkitt's Lymphoma, CNS Embryonal Tumors, CNS Germ Cell Tumors, CNS Sarcoma, Choroid Plexus Tumors, Chronic Myelogenous Leukemia (CML), Clear Cell Sarcoma of the Kidney, Craniopharyngioma, Diffuse Intrinsic Pontine Glioma (DIPG), Diffuse Large B-cell Lymphoma (DLBCL), Diffuse Midline Glioma (DMG), Ependymoma, Ewing Sarcoma, Germ Cell Tumors, Glioneuronal and Neuronal Tumors, Hepatoblastoma, Hepatocellular Carcinoma, High-Grade Glioma, Histiocytic Tumors, Hodgkin Lymphoma, Infant Leukemia, Juvenile Xanthogranuloma (JXG), Langerhans Cell Histiocytosis (LCH), Leukemia & Lymphoma, Liver Tumors, Low-Grade Glioma, Lymphoblastic Lymphoma (LBL), Malignant Bone Tumors, Medulloblastoma, Neuroblastoma, Newly diagnosed, Non-Hodgkin Lymphoma (NHL), Non-rhabdomyosarcoma Soft Tissue Sarcomas, Osteosarcoma, Other, Pheochromocytoma, Pilocytic Astrocytoma, Recurrent and/or Refractory, Registry, Renal Cell Carcinoma, Renal Tumors, Retinoblastoma, Rhabdoid Tumor of the Kidney, Rhabdomyosarcoma, Soft Tissue Sarcomas, Solid Tumor, Thyroid Cancer, Wilms Tumor
  • Phase: N/A
  • Clinicaltrials.gov ID: NCT02402244

What is the goal of the study?

The next generation of therapy for childhood cancers will be based upon in-depth molecular phenotyping that may facilitate the development of rational risk-adapted and target-based therapies. In order to support current and future molecularly-guided therapeutic trials and the basic science discovery efforts that will lead to more effective therapies, prevention, early detection and a reduction in early and late-onset toxicities, it is critical to implement universal, high-quality collection of annotated biospecimens from children with cancer. This protocol provides for the collection of biospecimens and accompanying demographic, epidemiologic, therapeutic, and outcome data from all children diagnosed with cancer at participating COG institutions, independent of the patient’s enrollment on a therapeutic clinical trial. Through this approach, the correlation of phenotypic and genotypic or other –omic data with the relevant outcomes at the individual, disease, and protocol levels will be ensured. Biospecimen requirements and handling may be disease specific and thus a detailed manual of procedures will provide disease specific information regarding sample collection and processing based on the clinical diagnosis.

Who can participate in the study?

Please contact the study team listed below to learn more.

Study Team: