Sarah E S Leary, MD, MS

Sarah E S Leary, MD, MS

Cancer and Blood Disorders Center, Brain Tumor Program

On staff since August 2009

Children's Title: Attending Physician and Medical Director, Pediatric Brain Tumor Program

Academic Title: Professor, Department of Pediatrics, University of Washington School of Medicine

Research Center: Ben Towne Center for Childhood Cancer Research

"It is a privilege to work with children as part of a multidisciplinary team of clinicians and researchers who are so dedicated to providing the best care for our patients today while at the same time working to find a cure for every child in the future. My favorite days are those when I receive notes and pictures from my former patients who now are living long, healthy lives free of cancer."

  • Biography

    Sarah Leary, MD, is an Attending Physician and Medical Director of the Pediatric Brain Tumor Program in the Cancer and Blood Disorders Center at Seattle Children’s Hospital. She is a Professor of Pediatrics at the University of Washington School of Medicine and associate of the Fred Hutchinson Cancer Research Center. Dr. Leary is a leader in clinical and translational research with a goal of improving outcomes for children, adolescents and young adults with brain tumors.

    Locally, she serves as the Medical Director of Clinical Research at the Ben Towne Center for Childhood Cancer Research, leads the Seattle Children’s Tumor Banking and Biology study, and serves as the Seattle Children’s site Principal Investigator for the Children’s Oncology Group and CONNECT Clinical trials consortia. Nationally, she is the clinical Vice-Chair of the Central Nervous System Committee of the Children’s Oncology Group; the chair of the Data Safety Monitoring Committee of the Pediatric Brain Tumor Consortium; and a member of the Brain Malignancy Steering Committee of the National Cancer Institute. She is leading international data sharing efforts as the lead of the clinical data working group of the Children’s Brain Tumor Network (CBTN) and the Co-Chair of the Executive Committee of the INSPiRE consortium. 

  • Patient Testimonials

    • Brandon Puyallup, WA 06.05.23

      Dr. Leary is a great, smart and nice doctor.

  • Awards and Honors

    Award Name Award Description Awarded By Award Date
    Seattle Top Doctor - 2023 Seattle Met 2023
    Seattle Top Doctor - 2022 Seattle Met 2022
    Alpha Omega Alpha University of Tennessee College of Medicine 2001
    Outstanding Student in Neurology University of Tennessee College of Medicine 2001
    Family Choice Award Nomination 2011 and 2013 The Family Advisory Council invites patients and families to nominate a staff member who demonstrates the qualities of Family Centered Care
  • Publications

    Other Publications

    • Haas-Kogan DA, Aboian MS, Minturn JE, Leary SES, Abdelbaki MS, Goldman S, Elster JD, Kraya A, Lueder MR, Ramakrishnan D, von Reppert M, Liu KX, Rokita JL, Resnick AC, Solomon DA, Phillips JJ, Prados M, Molinaro AM, Waszak SM, Mueller S
      Everolimus for Children With Recurrent or Progressive Low-Grade Glioma: Results From the Phase II PNOC001 Trial.
      37978951 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023 Nov 17 : JCO2301838
    • Kilburn LB, Khuong-Quang DA, Hansford JR, Landi D, van der Lugt J, Leary SES, Driever PH, Bailey S, Perreault S, McCowage G, Waanders AJ, Ziegler DS, Witt O, Baxter PA, Kang HJ, Hassall TE, Han JW, Hargrave D, Franson AT, Yalon Oren M, Toledano H, Larouche V, Kline C, Abdelbaki MS, Jabado N, Gottardo NG, Gerber NU, Whipple NS, Segal D, Chi SN, Oren L, Tan EEK, Mueller S, Cornelio I, McLeod L, Zhao X, Walter A, Da Costa D, Manley P, Blackman SC, Packer RJ, Nysom K
      The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial.
      37978284 Nature medicine, 2023 Nov 17
    • Familiar AM, Kazerooni AF, Anderson H, Lubneuski A, Viswanathan K, Breslow R, Khalili N, Bagheri S, Haldar D, Kim MC, Arif S, Madhogarhia R, Nguyen TQ, Frenkel EA, Helili Z, Harrison J, Farahani K, Linguraru MG, Bagci U, Velichko Y, Stevens J, Leary S, Lober RM, Campion S, Smith AA, Morinigo D, Rood B, Diamond K, Pollack IF, Williams M, Vossough A, Ware JB, Mueller S, Storm PB, Heath AP, Waanders AJ, Lilly J, Mason JL, Resnick AC, Nabavizadeh A
      A multi-institutional pediatric dataset of clinical radiology MRIs by the Children's Brain Tumor Network.
      38106459 ArXiv, 2023 Oct 2 : PMCID:PMC10723526
    • Leary SES, Onar-Thomas A, Fangusaro J, Gottardo NG, Cohen K, Smith A, Huang A, Haas-Kogan D, Fouladi M, COG Central Nervous System Committee
      Children's Oncology Group's 2023 blueprint for research: Central nervous system tumors.
      37534382 Pediatric blood & cancer, 2023 Sept. : 70 Suppl 6(Suppl 6)e30600 PMCID:PMC10569820
    • Noll A, Myers C, Biery MC, Meechan M, Tahiri S, Rajendran A, Berens ME, Paine D, Byron S, Zhang J, Winter C, Pakiam F, Leary SES, Cole BL, Jackson ER, Dun MD, Foster JB, Evans MK, Pattwell SS, Olson JM, Vitanza NA
      Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma.
      37603953 Neoplasia (New York, N.Y.), 2023 Sept. : 43100921 PMCID:PMC10465940
    • Paulson VA, Liu YJ, Fang H, Browd SR, Hauptman JS, Wright J, Lockwood CM, Leary SES, Cole BL
      Infantile ZFTA Fusion-Positive Tumor of the Posterior Fossa: Molecular Tumor Board.
      36862968 JCO precision oncology, 2023 March : 7e2200226
    • Vitanza NA, Ronsley R, Choe M, Henson C, Breedt M, Barrios-Anderson A, Wein A, Brown C, Beebe A, Kong A, Kirkey D, Lee BM, Leary SES, Crotty EE, Hoeppner C, Holtzclaw S, Wilson AL, Gustafson JA, Foster JB, Iliff JJ, Goldstein HE, Browd SR, Lee A, Ojemann JG, Pinto N, Gust J, Gardner RA, Jensen MC, Hauptman JS, Park JR
      Locoregional CAR T cells for children with CNS tumors: Clinical procedure and catheter safety.
      36599192 Neoplasia (New York, N.Y.), 2023 Feb. : 36100870 PMCID:PMC9823206
    • Vitanza NA, Wilson AL, Huang W, Seidel K, Brown C, Gustafson JA, Yokoyama JK, Johnson AJ, Baxter BA, Koning RW, Reid AN, Meechan M, Biery MC, Myers C, Rawlings-Rhea SD, Albert CM, Browd SR, Hauptman JS, Lee A, Ojemann JG, Berens ME, Dun MD, Foster JB, Crotty EE, Leary SES, Cole BL, Perez FA, Wright JN, Orentas RJ, Chour T, Newell EW, Whiteaker JR, Zhao L, Paulovich AG, Pinto N, Gust J, Gardner RA, Jensen MC, Park JR
      Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety.
      36259971 Cancer discovery, 2023 Jan 9 : 13(1)114-131 PMCID:PMC9827115
    • Cooney T, Lindsay H, Leary S, Wechsler-Reya R
      Current studies and future directions for medulloblastoma: A review from the pacific pediatric neuro-oncology consortium (PNOC) disease working group.
      36516489 Neoplasia (New York, N.Y.), 2023 Jan. : 35100861 PMCID:PMC9755363
    • Boop S, Bonda D, Randle S, Leary S, Vitanza N, Crotty E, Novotny E, Friedman S, Ellenbogen RG, Durfy S, Goldstein H, Ojemann JG, Hauptman JS
      A Comparison of Clinical Outcomes for Subependymal Giant Cell Astrocytomas Treated with Laser Interstitial Thermal Therapy, Open Surgical Resection, and mTOR Inhibitors.
      37232001 Pediatric neurosurgery, 2023 : 58(3)150-159
    • Lilly JV, Rokita JL, Mason JL, Patton T, Stefankiewiz S, Higgins D, Trooskin G, Larouci CA, Arya K, Appert E, Heath AP, Zhu Y, Brown MA, Zhang B, Farrow BK, Robins S, Morgan AM, Nguyen TQ, Frenkel E, Lehmann K, Drake E, Sullivan C, Plisiewicz A, Coleman N, Patterson L, Koptyra M, Helili Z, Van Kuren N, Young N, Kim MC, Friedman C, Lubneuski A, Blackden C, Williams M, Baubet V, Tauhid L, Galanaugh J, Boucher K, Ijaz H, Cole KA, Choudhari N, Santi M, Moulder RW, Waller J, Rife W, Diskin SJ, Mateos M, Parsons DW, Pollack IF, Goldman S, Leary S, Caporalini C, Buccoliero AM, Scagnet M, Haussler D, Hanson D, Firestein R, Cain J, Phillips JJ, Gupta N, Mueller S, Grant G, Monje-Deisseroth M, Partap S, Greenfield JP, Hashizume R, Smith A, Zhu S, Johnston JM, Fangusaro JR, Miller M, Wood MD, Gardner S, Carter CL, Prolo LM, Pisapia J, Pehlivan K, Franson A, Niazi T, Rubin J, Abdelbaki M, Ziegler DS, Lindsay HB, Stucklin AG, Gerber N, Vaske OM, Quinsey C, Rood BR, Nazarian J, Raabe E, Jackson EM, Stapleton S, Lober RM, Kram DE, Koschmann C, Storm PB, Lulla RR, Prados M, Resnick AC, Waanders AJ
      The children's brain tumor network (CBTN) - Accelerating research in pediatric central nervous system tumors through collaboration and open science.
      36335802 Neoplasia (New York, N.Y.), 2023 Jan. : 35100846 PMCID:PMC9641002
    • Lazow MA, Nievelstein MT, Lane A, Bandopadhayhay P, DeWire-Schottmiller M, Fouladi M, Glod JW, Greiner RJ, Hoffman LM, Hummel TR, Kilburn L, Leary S, Minturn JE, Packer R, Ziegler DS, Chaney B, Black K, de Blank P, Leach JL
      Volumetric endpoints in diffuse intrinsic pontine glioma: comparison to cross-sectional measures and outcome correlations in the International DIPG/DMG Registry.
      35148393 Neuro-oncology, 2022 Sep 1 : 24(9)1598-1608 PMCID:PMC9435485
    • Cole BL, Starr K, Lockwood CM, Leary SES
      The "SEED" Study: The Feasibility of Selecting Patient-Specific Biologically Targeted Therapy with Sorafenib, Everolimus, Erlotinib or Dasatinib for Pediatric and Young Adult Patients with Recurrent or Refractory Brain Tumors.
      35866410 Frontiers in bioscience (Landmark edition), 2022 Jul 12 : 27(7)219
    • Leary SES, Kilburn L, Geyer JR, Kocak M, Huang J, Smith KS, Hadley J, Ermoian R, MacDonald TJ, Goldman S, Phillips P, Young Poussaint T, Olson JM, Ellison DW, Dunkel IJ, Fouladi M, Onar-Thomas A, Northcott PA
      Vorinostat and isotretinoin with chemotherapy in young children with embryonal brain tumors: A report from the Pediatric Brain Tumor Consortium (PBTC-026).
      34935967 Neuro-oncology, 2022 Jul 1 : 24(7)1178-1190 PMCID:PMC9248403
    • Bartels U, Onar-Thomas A, Patel SK, Shaw D, Fangusaro J, Dhall G, Souweidane M, Bhatia A, Embry L, Trask CL, Murphy ES, MacDonald S, Wu S, Boyett JM, Leary S, Fouladi M, Gajjar A, Khatua S
      Phase II trial of response-based radiation therapy for patients with localized germinoma: a Children's Oncology Group study.
      34850169 Neuro-oncology, 2022 Jun 1 : 24(6)974-983 PMCID:PMC9159444
    • Lazow MA, Fuller C, DeWire M, Lane A, Bandopadhayay P, Bartels U, Bouffet E, Cheng S, Cohen KJ, Cooney TM, Coven SL, Dholaria H, Diez B, Dorris K, El-Ayadi M, El-Sheikh A, Fisher PG, Fonseca A, Garcia Lombardi M, Greiner RJ, Goldman S, Gottardo N, Gururangan S, Hansford JR, Hassall T, Hawkins C, Kilburn L, Koschmann C, Leary SE, Ma J, Minturn JE, Monje-Deisseroth M, Packer R, Samson Y, Sandler ES, Sevlever G, Tinkle CL, Tsui K, Wagner LM, Zaghloul M, Ziegler DS, Chaney B, Black K, Asher A, Drissi R, Fouladi M, Jones BV, Leach JL
      Accuracy of central neuro-imaging review of DIPG compared with histopathology in the International DIPG Registry.
      34668975 Neuro-oncology, 2022 May 4 : 24(5)821-833 PMCID:PMC9071293
    • Scherpelz KP, Crotty EE, Paulson VA, Lockwood CM, Leary SES, Ellenbogen RG, Lee A, Ermoian RP, Vitanza NA, Cole BL
      Two cases of pineal anlage tumor with molecular analysis.
      35129878 Pediatric blood & cancer, 2022 April : 69(4)e29596
    • Jiang B, Murray C, Cole BL, Glover JNM, Chan GK, Deschenes J, Mani RS, Subedi S, Nerva JD, Wang AC, Lockwood CM, Mefford HC, Leary SES, Ojemann JG, Weinfeld M, Ene CI
      Mutations of the DNA repair gene PNKP in a patient with microcephaly, seizures, and developmental delay (MCSZ) presenting with a high-grade brain tumor.
      35354845 Scientific reports, 2022 Mar 30 : 12(1)5386 PMCID:PMC8967877
    • Leary SES, Li Y, Olson JM
      Carboplatin During Craniospinal Radiotherapy for Children With Group 3 Medulloblastoma-A New Standard of Care?-Reply.
      34882234 JAMA oncology, 2022 Feb 1 : 8(2)302-303
    • Erker C, Lane A, Chaney B, Leary S, Minturn JE, Bartels U, Packer RJ, Dorris K, Gottardo NG, Warren KE, Broniscer A, Kieran MW, Zhu X, White P, Dexheimer PJ, Black K, Asher A, DeWire M, Hansford JR, Gururangan S, Nazarian J, Ziegler DS, Sandler E, Bartlett A, Goldman S, Shih CS, Hassall T, Dholaria H, Bandopadhayay P, Samson Y, Monje M, Fisher PG, Dodgshun A, Parkin S, Chintagumpala M, Tsui K, Gass D, Larouche V, Broxson E, Garcia Lombardi M, Wang SS, Ma J, Hawkins C, Hamideh D, Wagner L, Koschmann C, Fuller C, Drissi R, Jones BV, Leach J, Fouladi M
      Characteristics of patients ≥10 years of age with diffuse intrinsic pontine glioma: a report from the International DIPG/DMG Registry.
      34114629 Neuro-oncology, 2022 Jan 5 : 24(1)141-152 PMCID:PMC8730773
    • Hansford JR, Huang J, Endersby R, Dodgshun AJ, Li BK, Hwang E, Leary S, Gajjar A, Von Hoff K, Wells O, Wray A, Kotecha RS, Raleigh DR, Stoller S, Mueller S, Schild SE, Bandopadhayay P, Fouladi M, Bouffet E, Huang A, Onar-Thomas A, Gottardo NG
      Pediatric pineoblastoma: A pooled outcome study of North American and Australian therapeutic data.
      35664557 Neuro-oncology advances, 2022 Jan. : 4(1)vdac056 PMCID:PMC9154333
    • DeWire M, Lazow M, Campagne O, Leach J, Fuller C, Senthil Kumar S, Stanek J, de Blank P, Hummel TR, Pillay-Smiley N, Salloum R, Stevenson CB, Baxter P, Gass D, Goldman S, Leary SES, Carle A, Mikael L, Crabtree D, Chaney B, Lane A, Drissi R, Stewart CF, Fouladi M
      Phase I study of ribociclib and everolimus in children with newly diagnosed DIPG and high-grade glioma: A CONNECT pediatric neuro-oncology consortium report.
      35611273 Neuro-oncology advances, 2022 Jan. : 4(1)vdac055 PMCID:PMC9122788
    • Khan S, Solano-Paez P, Suwal T, Lu M, Al-Karmi S, Ho B, Mumal I, Shago M, Hoffman LM, Dodgshun A, Nobusawa S, Tabori U, Bartels U, Ziegler DS, Hansford JR, Ramaswamy V, Hawkins C, Dufour C, André N, Bouffet E, Huang A, Rare Brain Tumor Registry
      Clinical phenotypes and prognostic features of embryonal tumours with multi-layered rosettes: a Rare Brain Tumor Registry study.
      34599879 The Lancet. Child & adolescent health, 2021 Nov. : 5(11)800-813
    • Wang S, Sun MZ, Abecassis IJ, Weil AG, Ibrahim GM, Fallah A, Ene C, Leary SES, Cole BL, Lockwood CM, Olson JM, Geyer JR, Ellenbogen RG, Ojemann JG, Wang AC
      Predictors of mortality and tumor recurrence in desmoplastic infantile ganglioglioma and astrocytoma-and individual participant data meta-analysis (IPDMA).
      34613581 Journal of neuro-oncology, 2021 Nov. : 155(2)155-163 PMCID:PMC9448015
    • Coltin H, Sundaresan L, Smith KS, Skowron P, Massimi L, Eberhart CG, Schreck KC, Gupta N, Weiss WA, Tirapelli D, Carlotti C, Li KKW, Ryzhova M, Golanov A, Zheludkova O, Absalyamova O, Okonechnikov K, Stichel D, von Deimling A, Giannini C, Raskin S, Van Meir EG, Chan JA, Fults D, Chambless LB, Kim SK, Vasiljevic A, Faure-Conter C, Vibhakar R, Jung S, Leary S, Mora J, McLendon RE, Pollack IF, Hauser P, Grajkowska WA, Rubin JB, van Veelen MC, French PJ, Kros JM, Liau LM, Pfister SM, Kool M, Kijima N, Taylor MD, Packer RJ, Northcott PA, Korshunov A, Ramaswamy V
      Subgroup and subtype-specific outcomes in adult medulloblastoma.
      34409497 Acta neuropathologica, 2021 Nov. : 142(5)859-871
    • Leary SES, Packer RJ, Li Y, Billups CA, Smith KS, Jaju A, Heier L, Burger P, Walsh K, Han Y, Embry L, Hadley J, Kumar R, Michalski J, Hwang E, Gajjar A, Pollack IF, Fouladi M, Northcott PA, Olson JM
      Efficacy of Carboplatin and Isotretinoin in Children With High-risk Medulloblastoma: A Randomized Clinical Trial From the Children's Oncology Group.
      34292305 JAMA oncology, 2021 Sep 1 : 7(9)1313-1321 PMCID:PMC8299367
    • Van Mater D, Gururangan S, Becher O, Campagne O, Leary S, Phillips JJ, Huang J, Lin T, Poussaint TY, Goldman S, Baxter P, Dhall G, Robinson G, DeWire-Schottmiller M, Hwang EI, Stewart CF, Onar-Thomas A, Dunkel IJ, Fouladi M
      A phase I trial of the CDK 4/6 inhibitor palbociclib in pediatric patients with progressive brain tumors: A Pediatric Brain Tumor Consortium study (PBTC-042).
      33405376 Pediatric blood & cancer, 2021 April : 68(4)e28879 PMCID:PMC8414988
    • Vitanza NA, Biery MC, Myers C, Ferguson E, Zheng Y, Girard EJ, Przystal JM, Park G, Noll A, Pakiam F, Winter CA, Morris SM, Sarthy J, Cole BL, Leary SES, Crane C, Lieberman NAP, Mueller S, Nazarian J, Gottardo R, Brusniak MY, Mhyre AJ, Olson JM
      Optimal therapeutic targeting by HDAC inhibition in biopsy-derived treatment-naïve diffuse midline glioma models.
      33130903 Neuro-oncology, 2021 Mar 25 : 23(3)376-386 PMCID:PMC7992886
    • Vitanza NA, Khalatbari H, Ermoian R, Sarthy J, Lockwood CM, Cole BL, Leary SES
      Molecularly Targeted Treatments for NF1-Mutant Diffuse Intrinsic Pontine Glioma.
      32862234 The journal of applied laboratory medicine, 2021 Mar 1 : 6(2)550-553
    • Kumar R, Smith KS, Deng M, Terhune C, Robinson GW, Orr BA, Liu APY, Lin T, Billups CA, Chintagumpala M, Bowers DC, Hassall TE, Hansford JR, Khuong-Quang DA, Crawford JR, Bendel AE, Gururangan S, Schroeder K, Bouffet E, Bartels U, Fisher MJ, Cohn R, Partap S, Kellie SJ, McCowage G, Paulino AC, Rutkowski S, Fleischhack G, Dhall G, Klesse LJ, Leary S, Nazarian J, Kool M, Wesseling P, Ryzhova M, Zheludkova O, Golanov AV, McLendon RE, Packer RJ, Dunham C, Hukin J, Fouladi M, Faria CC, Pimentel J, Walter AW, Jabado N, Cho YJ, Perreault S, Croul SE, Zapotocky M, Hawkins C, Tabori U, Taylor MD, Pfister SM, Klimo P Jr, Boop FA, Ellison DW, Merchant TE, Onar-Thomas A, Korshunov A, Jones DTW, Gajjar A, Ramaswamy V, Northcott PA
      Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma.
      33502920 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021 Mar 1 : 39(7)807-821 PMCID:PMC8078396
    • Van Mater D, Gururangan S, Becher O, Campagne O, Leary S, Phillips JJ, Huang J, Lin T, Poussaint TY, Goldman S, Baxter P, Dhall G, Robinson G, DeWire-Schottmiller M, Hwang EI, Stewart CF, Onar-Thomas A, Dunkel IJ, Fouladi M
      A phase I trial of the CDK 4/6 inhibitor palbociclibin pediatric patients with progressive brain tumors: A Pediatric Brain Tumor Consortium study (PBTC-042).
      33405376 Pediatric blood & cancer, 2021 Jan 6 : e28879
    • Carlberg VM, Davies OMT, Brandling-Bennett HA, Leary SES, Huang JT, Coughlin CC, Gupta D
      Cutaneous reactions to pediatric cancer treatment part II: Targeted therapy.
      33378085 Pediatric dermatology, 2021 Jan. : 38(1)18-30
    • Petralia F, Tignor N, Reva B, Koptyra M, Chowdhury S, Rykunov D, Krek A, Ma W, Zhu Y, Ji J, Calinawan A, Whiteaker JR, Colaprico A, Stathias V, Omelchenko T, Song X, Raman P, Guo Y, Brown MA, Ivey RG, Szpyt J, Guha Thakurta S, Gritsenko MA, Weitz KK, Lopez G, Kalayci S, Gümüş ZH, Yoo S, da Veiga Leprevost F, Chang HY, Krug K, Katsnelson L, Wang Y, Kennedy JJ, Voytovich UJ, Zhao L, Gaonkar KS, Ennis BM, Zhang B, Baubet V, Tauhid L, Lilly JV, Mason JL, Farrow B, Young N, Leary S, Moon J, Petyuk VA, Nazarian J, Adappa ND, Palmer JN, Lober RM, Rivero-Hinojosa S, Wang LB, Wang JM, Broberg M, Chu RK, Moore RJ, Monroe ME, Zhao R, Smith RD, Zhu J, Robles AI, Mesri M, Boja E, Hiltke T, Rodriguez H, Zhang B, Schadt EE, Mani DR, Ding L, Iavarone A, Wiznerowicz M, Schürer S, Chen XS, Heath AP, Rokita JL, Nesvizhskii AI, Fenyö D, Rodland KD, Liu T, Gygi SP, Paulovich AG, Resnick AC, Storm PB, Rood BR, Wang P, Children’s Brain Tumor Network., Clinical Proteomic Tumor Analysis Consortium.
      Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer.
      33242424 Cell, 2020 Dec 23 : 183(7)1962-1985.e31
    • Leach JL, Roebker J, Schafer A, Baugh J, Chaney B, Fuller C, Fouladi M, Lane A, Doughman R, Drissi R, DeWire-Schottmiller M, Ziegler DS, Minturn JE, Hansford JR, Wang SS, Monje-Deisseroth M, Fisher PG, Gottardo NG, Dholaria H, Packer R, Warren K, Leary SES, Goldman S, Bartels U, Hawkins C, Jones BV
      MR imaging features of diffuse intrinsic pontine glioma and relationship to overall survival: report from the International DIPG Registry.
      32506137 Neuro-oncology, 2020 Nov 26 : 22(11)1647-1657 PMCID:PMC7690352
    • Miklja Z, Yadav VN, Cartaxo RT, Siada R, Thomas CC, Cummings JR, Mullan B, Stallard S, Paul A, Bruzek AK, Wierzbicki K, Yang T, Garcia T, Wolfe I, Leonard M, Robertson PL, Garton HJ, Wahl DR, Parmar H, Sarkaria JN, Kline C, Mueller S, Nicolaides T, Glasser C, Leary SE, Venneti S, Kumar-Sinha C, Chinnaiyan AM, Mody R, Pai MP, Phoenix TN, Marini BL, Koschmann C
      Everolimus improves the efficacy of dasatinib in PDGFRα-driven glioma.
      32603316 The Journal of clinical investigation, 2020 Oct 1 : 130(10)5313-5325 PMCID:PMC7524471
    • Crotty EE, Leary SES, Geyer JR, Olson JM, Millard NE, Sato AA, Ermoian RP, Cole BL, Lockwood CM, Paulson VA, Browd SR, Ellenbogen RG, Hauptman JS, Lee A, Ojemann JG, Vitanza NA
      Children with DIPG and high-grade glioma treated with temozolomide, irinotecan, and bevacizumab: the Seattle Children's Hospital experience.
      32556862 Journal of neuro-oncology, 2020 July : 148(3)607-617
    • Nobre L, Zapotocky M, Khan S, Fukuoka K, Fonseca A, McKeown T, Sumerauer D, Vicha A, Grajkowska WA, Trubicka J, Li KKW, Ng HK, Massimi L, Lee JY, Kim SK, Zelcer S, Vasiljevic A, Faure-Conter C, Hauser P, Lach B, van Veelen-Vincent ML, French PJ, Van Meir EG, Weiss WA, Gupta N, Pollack IF, Hamilton RL, Nageswara Rao AA, Giannini C, Rubin JB, Moore AS, Chambless LB, Vibhakar R, Ra YS, Massimino M, McLendon RE, Wheeler H, Zollo M, Ferruci V, Kumabe T, Faria CC, Sterba J, Jung S, López-Aguilar E, Mora J, Carlotti CG, Olson JM, Leary S, Cain J, Krskova L, Zamecnik J, Hawkins CE, Tabori U, Huang A, Bartels U, Northcott PA, Taylor MD, Yip S, Hansford JR, Bouffet E, Ramaswamy V
      Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma.
      32743560 Cell reports. Medicine, 2020 Jun 23 : 1(3) PMCID:PMC7394286
    • Nicolaides T, Nazemi KJ, Crawford J, Kilburn L, Minturn J, Gajjar A, Gauvain K, Leary S, Dhall G, Aboian M, Robinson G, Long-Boyle J, Wang H, Molinaro AM, Mueller S, Prados M
      Phase I study of vemurafenib in children with recurrent or progressive BRAFV600E mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002).
      32523649 Oncotarget, 2020 May 26 : 11(21)1942-1952 PMCID:PMC7260122
    • Li BK, Vasiljevic A, Dufour C, Yao F, Ho BLB, Lu M, Hwang EI, Gururangan S, Hansford JR, Fouladi M, Nobusawa S, Laquerriere A, Delisle MB, Fangusaro J, Forest F, Toledano H, Solano-Paez P, Leary S, Birks D, Hoffman LM, Szathmari A, Faure-Conter C, Fan X, Catchpoole D, Zhou L, Schultz KAP, Ichimura K, Gauchotte G, Jabado N, Jones C, Loussouarn D, Mokhtari K, Rousseau A, Ziegler DS, Tanaka S, Pomeroy SL, Gajjar A, Ramaswamy V, Hawkins C, Grundy RG, Hill DA, Bouffet E, Huang A, Jouvet A
      Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain Tumor Consortium registry study.
      31820118 Acta neuropathologica, 2020 Feb. : 139(2)223-241 PMCID:PMC7673644
    • McEwen AE, Leary SES, Lockwood CM
      Beyond the Blood: CSF-Derived cfDNA for Diagnosis and Characterization of CNS Tumors.
      32133357 Frontiers in cell and developmental biology, 2020 : 845 PMCID:PMC7039816
    • Nobre L, Zapotocky M, Ramaswamy V, Ryall S, Bennett J, Alderete D, Balaguer Guill J, Baroni L, Bartels U, Bavle A, Bornhorst M, Boue DR, Canete A, Chintagumpala M, Coven SL, Cruz O, Dahiya S, Dirks P, Dunkel IJ, Eisenstat D, Faure Conter C, Finch E, Finlay JL, Frappaz D, Garre ML, Gauvain K, Bechensteen AG, Hansford JR, Harting I, Hauser P, Hazrati LN, Huang A, Injac SG, Iurilli V, Karajannis M, Kaur G, Kyncl M, Krskova L, Laperriere N, Larouche V, Lassaletta A, Leary S, Lin F, Mascelli S, McKeown T, Milde T, Morales La Madrid A, Morana G, Morse H, Mushtaq N, Osorio DS, Packer R, Pavelka Z, Quiroga-Cantero E, Rutka J, Sabel M, Salgado D, Solano P, Sterba J, Su J, Sumerauer D, Taylor MD, Toledano H, Tsang DS, Valente Fernandes M, van Landeghem F, van Tilburg CM, Wilson B, Witt O, Zamecnik J, Bouffet E, Hawkins C, Tabori U
      Outcomes of BRAF V600E Pediatric Gliomas Treated With Targeted BRAF Inhibition.
      32923898 JCO precision oncology, 2020 : 4 PMCID:PMC7446502
    • Bledsoe JC, Breiger D, Breiger M, Shonka S, Ermoian RP, Ojemann JG, Werny DM, Leary SES, Geyer JR
      Differential trajectories of neurocognitive functioning in females versus males following treatment for pediatric brain tumors.
      31123753 Neuro-oncology, 2019 Oct 9 : 21(10)1310-1318 PMCID:PMC6784260
    • Sin-Chan P, Mumal I, Suwal T, Ho B, Fan X, Singh I, Du Y, Lu M, Patel N, Torchia J, Popovski D, Fouladi M, Guilhamon P, Hansford JR, Leary S, Hoffman LM, Mulcahy Levy JM, Lassaletta A, Solano-Paez P, Rivas E, Reddy A, Gillespie GY, Gupta N, Van Meter TE, Nakamura H, Wong TT, Ra YS, Kim SK, Massimi L, Grundy RG, Fangusaro J, Johnston D, Chan J, Lafay-Cousin L, Hwang EI, Wang Y, Catchpoole D, Michaud J, Ellezam B, Ramanujachar R, Lindsay H, Taylor MD, Hawkins CE, Bouffet E, Jabado N, Singh SK, Kleinman CL, Barsyte-Lovejoy D, Li XN, Dirks PB, Lin CY, Mack SC, Rich JN, Huang A
      A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.
      31287992 Cancer cell, 2019 Jul 8 : 36(1)51-67.e7
    • Miklja Z, Pasternak A, Stallard S, Nicolaides T, Kline-Nunnally C, Cole B, Beroukhim R, Bandopadhayay P, Chi S, Ramkissoon SH, Mullan B, Bruzek AK, Gauthier A, Garcia T, Atchison C, Marini B, Fouladi M, Parsons DW, Leary S, Mueller S, Ligon KL, Koschmann C
      Molecular profiling and targeted therapy in pediatric gliomas: review and consensus recommendations.
      30805642 Neuro-oncology, 2019 Feb 26 : PMCID:PMC6682212
    • Barkley AS, Kuo CH, Leary SES, Ojemann JG, Susarla SM
      Unusual Radiographic Presentation of Intracranial Mature Teratoma and Resection via Supraorbital Approach.
      30368015 World neurosurgery, 2019 Feb. : 12281-84
    • Lieberman NAP, DeGolier K, Kovar HM, Davis A, Hoglund V, Stevens J, Winter C, Deutsch G, Furlan SN, Vitanza NA, Leary SES, Crane CA
      Characterization of the immune microenvironment of diffuse intrinsic pontine glioma: implications for development of immunotherapy.
      30169876 Neuro-oncology, 2019 Jan 1 : 21(1)83-94 PMCID:PMC6303470
    • Brabetz S, Leary SES, Gröbner SN, Nakamoto MW, Åžeker-Cin H, Girard EJ, Cole B, Strand AD, Bloom KL, Hovestadt V, Mack NL, Pakiam F, Schwalm B, Korshunov A, Balasubramanian GP, Northcott PA, Pedro KD, Dey J, Hansen S, Ditzler S, Lichter P, Chavez L, Jones DTW, Koster J, Pfister SM, Kool M, Olson JM
      A biobank of patient-derived pediatric brain tumor models.
      30349086 Nature medicine, 2018 Nov. : 24(11)1752-1761
    • Hwang EI, Kool M, Burger PC, Capper D, Chavez L, Brabetz S, Williams-Hughes C, Billups C, Heier L, Jaju A, Michalski J, Li Y, Leary S, Zhou T, von Deimling A, Jones DTW, Fouladi M, Pollack IF, Gajjar A, Packer RJ, Pfister SM, Olson JM
      Extensive Molecular and Clinical Heterogeneity in Patients With Histologically Diagnosed CNS-PNET Treated as a Single Entity: A Report From the Children's Oncology Group Randomized ACNS0332 Trial.
      30332335 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018 Oct 17 : JCO2017764720
    • Gupta N, Goumnerova LC, Manley P, Chi SN, Neuberg D, Puligandla M, Fangusaro J, Goldman S, Tomita T, Alden T, DiPatri A, Rubin JB, Gauvain K, Limbrick D, Leonard J, Geyer JR, Leary S, Browd S, Wang Z, Sood S, Bendel A, Nagib M, Gardner S, Karajannis MA, Harter D, Ayyanar K, Gump W, Bowers DC, Weprin B, MacDonald TJ, Aguilera D, Brahma B, Robison NJ, Kiehna E, Krieger M, Sandler E, Aldana P, Khatib Z, Ragheb J, Bhatia S, Mueller S, Banerjee A, Bredlau AL, Gururangan S, Fuchs H, Cohen KJ, Jallo G, Dorris K, Handler M, Comito M, Dias M, Nazemi K, Baird L, Murray J, Lindeman N, Hornick JL, Malkin H, Sinai C, Greenspan L, Wright KD, Prados M, Bandopadhayay P, Ligon KL, Kieran MW
      Prospective feasibility and safety assessment of surgical biopsy for patients with newly diagnosed diffuse intrinsic pontine glioma.
      29741745 Neuro-oncology, 2018 Oct 9 : 20(11)1547-1555 PMCID:PMC6176802
    • Maloney E, Stanescu AL, Perez FA, Iyer RS, Otto RK, Leary S, Steuten L, Phipps AI, Shaw DWW
      Surveillance magnetic resonance imaging for isolated optic pathway gliomas: is gadolinium necessary?
      29789890 Pediatric radiology, 2018 Sept. : 48(10)1472-1484
    • Manley PE, Trippett T, Smith AA, Macy ME, Leary SES, Boklan J, Cohen KJ, Goldman S, Kilburn LB, Dhall G, Devin J, Herzog CE, Partap S, Fauchet F, Badreddine E, Bernard JP, Chi SN
      A phase 1/2 dose-finding, safety, and activity study of cabazitaxel in pediatric patients with refractory solid tumors including tumors of the central nervous system.
      29750396 Pediatric blood & cancer, 2018 Sept. : 65(9)e27217
    • Cavalli FMG, Hübner JM, Sharma T, Luu B, Sill M, Zapotocky M, Mack SC, Witt H, Lin T, Shih DJH, Ho B, Santi M, Emery L, Hukin J, Dunham C, McLendon RE, Lipp ES, Gururangan S, Grossbach A, French P, Kros JM, van Veelen MC, Rao AAN, Giannini C, Leary S, Jung S, Faria CC, Mora J, Schüller U, Alonso MM, Chan JA, Klekner A, Chambless LB, Hwang EI, Massimino M, Eberhart CG, Karajannis MA, Lu B, Liau LM, Zollo M, Ferrucci V, Carlotti C, Tirapelli DPC, Tabori U, Bouffet E, Ryzhova M, Ellison DW, Merchant TE, Gilbert MR, Armstrong TS, Korshunov A, Pfister SM, Taylor MD, Aldape K, Pajtler KW, Kool M, Ramaswamy V
      Heterogeneity within the PF-EPN-B ependymoma subgroup.
      30019219 Acta neuropathologica, 2018 Aug. : 136(2)227-237 PMCID:PMC6373486
    • Gits HC, Anderson M, Stallard S, Pratt D, Zon B, Howell C, Kumar-Sinha C, Vats P, Kasaian K, Polan D, Matuszak M, Spratt DE, Leonard M, Qin T, Zhao L, Leach J, Chaney B, Escorza NY, Hendershot J, Jones B, Fuller C, Leary S, Bartels U, Bouffet E, Yock TI, Robertson P, Mody R, Venneti S, Chinnaiyan AM, Fouladi M, Gottardo NG, Koschmann C
      Medulloblastoma therapy generates risk of a poorly-prognostic H3 wild-type subgroup of diffuse intrinsic pontine glioma: a report from the International DIPG Registry.
      30049282 Acta neuropathologica communications, 2018 Jul 26 : 6(1)67 PMCID:PMC6062866
    • Hoffman LM, Veldhuijzen van Zanten SEM, Colditz N, Baugh J, Chaney B, Hoffmann M, Lane A, Fuller C, Miles L, Hawkins C, Bartels U, Bouffet E, Goldman S, Leary S, Foreman NK, Packer R, Warren KE, Broniscer A, Kieran MW, Minturn J, Comito M, Broxson E, Shih CS, Khatua S, Chintagumpala M, Carret AS, Escorza NY, Hassall T, Ziegler DS, Gottardo N, Dholaria H, Doughman R, Benesch M, Drissi R, Nazarian J, Jabado N, Boddaert N, Varlet P, Giraud G, Castel D, Puget S, Jones C, Hulleman E, Modena P, Giagnacovo M, Antonelli M, Pietsch T, Gielen GH, Jones DTW, Sturm D, Pfister SM, Gerber NU, Grotzer MA, Pfaff E, von Bueren AO, Hargrave D, Solanki GA, Jadrijevic Cvrlje F, Kaspers GJL, Vandertop WP, Grill J, Bailey S, Biassoni V, Massimino M, Calmon R, Sanchez E, Bison B, Warmuth-Metz M, Leach J, Jones B, van Vuurden DG, Kramm CM, Fouladi M
      Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.
      29746225 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018 Jul 1 : 36(19)1963-1972 PMCID:PMC6075859
    • Cole BL, Pritchard CC, Anderson M, Leary SE
      Targeted Sequencing of Malignant Supratentorial Pediatric Brain Tumors Demonstrates a High Frequency of Clinically Relevant Mutations.
      29173061 Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, 2018 July : 21(4)380-388
    • Kieran MW, Chisholm J, Casanova M, Brandes AA, Aerts I, Bouffet E, Bailey S, Leary S, MacDonald TJ, Mechinaud F, Cohen KJ, Riccardi R, Mason W, Hargrave D, Kalambakas S, Deshpande P, Tai F, Hurh E, Geoerger B
      Phase I study of oral sonidegib (LDE225) in pediatric brain and solid tumors and a phase II study in children and adults with relapsed medulloblastoma.
      28605510 Neuro-oncology, 2017 Oct 19 : 19(11)1542-1552 PMCID:PMC5737275
    • Leary SES, Park JR, Reid JM, Ralya AT, Baruchel S, Wu B, Roberts TPL, Liu X, Minard CG, Fox E, Weigel B, Blaney S
      Pediatric Phase I Trial and Pharmacokinetic Study of Trebananib in Relapsed Solid Tumors, Including Primary Tumors of the Central Nervous System ADVL1115: A Children's Oncology Group Phase I Consortium Report.
      28751444 Clinical cancer research : an official journal of the American Association for Cancer Research, 2017 Oct 15 : 23(20)6062-6069 PMCID:PMC5641249
    • Cooney T, Lane A, Bartels U, Bouffet E, Goldman S, Leary SES, Foreman NK, Packer RJ, Broniscer A, Minturn JE, Shih CS, Chintagumpala M, Hassall T, Gottardo NG, Dholaria H, Hoffman L, Chaney B, Baugh J, Doughman R, Leach JL, Jones BV, Fouladi M, Warren KE, Monje M
      Contemporary survival endpoints: an International Diffuse Intrinsic Pontine Glioma Registry study.
      28821206 Neuro-oncology, 2017 Sep 1 : 19(9)1279-1280 PMCID:PMC5570207
    • Lassaletta A, Zapotocky M, Mistry M, Ramaswamy V, Honnorat M, Krishnatry R, Guerreiro Stucklin A, Zhukova N, Arnoldo A, Ryall S, Ling C, McKeown T, Loukides J, Cruz O, de Torres C, Ho CY, Packer RJ, Tatevossian R, Qaddoumi I, Harreld JH, Dalton JD, Mulcahy-Levy J, Foreman N, Karajannis MA, Wang S, Snuderl M, Nageswara Rao A, Giannini C, Kieran M, Ligon KL, Garre ML, Nozza P, Mascelli S, Raso A, Mueller S, Nicolaides T, Silva K, Perbet R, Vasiljevic A, Faure Conter C, Frappaz D, Leary S, Crane C, Chan A, Ng HK, Shi ZF, Mao Y, Finch E, Eisenstat D, Wilson B, Carret AS, Hauser P, Sumerauer D, Krskova L, Larouche V, Fleming A, Zelcer S, Jabado N, Rutka JT, Dirks P, Taylor MD, Chen S, Bartels U, Huang A, Ellison DW, Bouffet E, Hawkins C, Tabori U
      Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas.
      28727518 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017 Sep 1 : 35(25)2934-2941 PMCID:PMC5791837
    • Cavalli FMG, Remke M, Rampasek L, Peacock J, Shih DJH, Luu B, Garzia L, Torchia J, Nor C, Morrissy AS, Agnihotri S, Thompson YY, Kuzan-Fischer CM, Farooq H, Isaev K, Daniels C, Cho BK, Kim SK, Wang KC, Lee JY, Grajkowska WA, Perek-Polnik M, Vasiljevic A, Faure-Conter C, Jouvet A, Giannini C, Nageswara Rao AA, Li KKW, Ng HK, Eberhart CG, Pollack IF, Hamilton RL, Gillespie GY, Olson JM, Leary S, Weiss WA, Lach B, Chambless LB, Thompson RC, Cooper MK, Vibhakar R, Hauser P, van Veelen MC, Kros JM, French PJ, Ra YS, Kumabe T, López-Aguilar E, Zitterbart K, Sterba J, Finocchiaro G, Massimino M, Van Meir EG, Osuka S, Shofuda T, Klekner A, Zollo M, Leonard JR, Rubin JB, Jabado N, Albrecht S, Mora J, Van Meter TE, Jung S, Moore AS, Hallahan AR, Chan JA, Tirapelli DPC, Carlotti CG, Fouladi M, Pimentel J, Faria CC, Saad AG, Massimi L, Liau LM, Wheeler H, Nakamura H, Elbabaa SK, Perezpeña-Diazconti M, Chico Ponce de León F, Robinson S, Zapotocky M, Lassaletta A, Huang A, Hawkins CE, Tabori U, Bouffet E, Bartels U, Dirks PB, Rutka JT, Bader GD, Reimand J, Goldenberg A, Ramaswamy V, Taylor MD
      Intertumoral Heterogeneity within Medulloblastoma Subgroups.
      28609654 Cancer cell, 2017 Jun 12 : 31(6)737-754.e6 PMCID:PMC6163053
    • Byers HM, Adam MP, LaCroix A, Leary SE, Cole B, Dobyns WB, Mefford HC
      Description of a new oncogenic mechanism for atypical teratoid rhabdoid tumors in patients with ring chromosome 22.
      27734605 American journal of medical genetics. Part A, 2017 Jan. : 173(1)245-249 PMCID:PMC5999866
    • Haberthur K, Brennan K, Hoglund V, Balcaitis S, Chinn H, Davis A, Kreuser S, Winter C, Leary SE, Deutsch GH, Ellenbogen RG, Crane CA
      NKG2D ligand expression in pediatric brain tumors.
      27834580 Cancer biology & therapy, 2016 Dec. : 17(12)1253-1265 PMCID:PMC5199167
    • Ramaswamy V, Hielscher T, Mack SC, Lassaletta A, Lin T, Pajtler KW, Jones DT, Luu B, Cavalli FM, Aldape K, Remke M, Mynarek M, Rutkowski S, Gururangan S, McLendon RE, Lipp ES, Dunham C, Hukin J, Eisenstat DD, Fulton D, van Landeghem FK, Santi M, van Veelen ML, Van Meir EG, Osuka S, Fan X, Muraszko KM, Tirapelli DP, Oba-Shinjo SM, Marie SK, Carlotti CG, Lee JY, Rao AA, Giannini C, Faria CC, Nunes S, Mora J, Hamilton RL, Hauser P, Jabado N, Petrecca K, Jung S, Massimi L, Zollo M, Cinalli G, Bognár L, Klekner A, Hortobágyi T, Leary S, Ermoian RP, Olson JM, Leonard JR, Gardner C, Grajkowska WA, Chambless LB, Cain J, Eberhart CG, Ahsan S, Massimino M, Giangaspero F, Buttarelli FR, Packer RJ, Emery L, Yong WH, Soto H, Liau LM, Everson R, Grossbach A, Shalaby T, Grotzer M, Karajannis MA, Zagzag D, Wheeler H, von Hoff K, Alonso MM, Tuñon T, Schüller U, Zitterbart K, Sterba J, Chan JA, Guzman M, Elbabaa SK, Colman H, Dhall G, Fisher PG, Fouladi M, Gajjar A, Goldman S, Hwang E, Kool M, Ladha H, Vera-Bolanos E, Wani K, Lieberman F, Mikkelsen T, Omuro AM, Pollack IF, Prados M, Robins HI, Soffietti R, Wu J, Metellus P, Tabori U, Bartels U, Bouffet E, Hawkins CE, Rutka JT, Dirks P, Pfister SM, Merchant TE, Gilbert MR, Armstrong TS, Korshunov A, Ellison DW, Taylor MD
      Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.
      27269943 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016 Jul 20 : 34(21)2468-77 PMCID:PMC4962737
    • Wetmore C, Daryani VM, Billups CA, Boyett JM, Leary S, Tanos R, Goldsmith KC, Stewart CF, Blaney SM, Gajjar A
      Phase II evaluation of sunitinib in the treatment of recurrent or refractory high-grade glioma or ependymoma in children: a children's Oncology Group Study ACNS1021.
      27109549 Cancer medicine, 2016 July : 5(7)1416-24 PMCID:PMC4944867
    • Thompson EM, Hielscher T, Bouffet E, Remke M, Luu B, Gururangan S, McLendon RE, Bigner DD, Lipp ES, Perreault S, Cho YJ, Grant G, Kim SK, Lee JY, Rao AAN, Giannini C, Li KKW, Ng HK, Yao Y, Kumabe T, Tominaga T, Grajkowska WA, Perek-Polnik M, Low DCY, Seow WT, Chang KTE, Mora J, Pollack IF, Hamilton RL, Leary S, Moore AS, Ingram WJ, Hallahan AR, Jouvet A, Fèvre-Montange M, Vasiljevic A, Faure-Conter C, Shofuda T, Kagawa N, Hashimoto N, Jabado N, Weil AG, Gayden T, Wataya T, Shalaby T, Grotzer M, Zitterbart K, Sterba J, Kren L, Hortobágyi T, Klekner A, László B, Pócza T, Hauser P, Schüller U, Jung S, Jang WY, French PJ, Kros JM, van Veelen MC, Massimi L, Leonard JR, Rubin JB, Vibhakar R, Chambless LB, Cooper MK, Thompson RC, Faria CC, Carvalho A, Nunes S, Pimentel J, Fan X, Muraszko KM, López-Aguilar E, Lyden D, Garzia L, Shih DJH, Kijima N, Schneider C, Adamski J, Northcott PA, Kool M, Jones DTW, Chan JA, Nikolic A, Garre ML, Van Meir EG, Osuka S, Olson JJ, Jahangiri A, Castro BA, Gupta N, Weiss WA, Moxon-Emre I, Mabbott DJ, Lassaletta A, Hawkins CE, Tabori U, Drake J, Kulkarni A, Dirks P, Rutka JT, Korshunov A, Pfister SM, Packer RJ, Ramaswamy V, Taylor MD
      Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis.
      26976201 The Lancet. Oncology, 2016 April : 17(4)484-495 PMCID:PMC4907853
    • Koschmann C, Bloom K, Upadhyaya S, Geyer JR, Leary SE
      Survival After Relapse of Medulloblastoma.
      26907655 Journal of pediatric hematology/oncology, 2016 Feb 22
    • Gajjar A, Bowers DC, Karajannis MA, Leary S, Witt H, Gottardo NG
      Pediatric Brain Tumors: Innovative Genomic Information Is Transforming the Diagnostic and Clinical Landscape.
      26304884 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015 Sep 20 : 33(27)2986-98 PMCID:PMC4567701
    • Voss SD, Glade-Bender J, Spunt SL, DuBois SG, Widemann BC, Park JR, Leary SE, Nelson MD, Adamson PC, Blaney SM, Weigel B
      Growth plate abnormalities in pediatric cancer patients undergoing phase 1 anti-angiogenic therapy: a report from the Children's Oncology Group Phase I Consortium.
      25257751 Pediatric blood & cancer, 2015 Jan. : 62(1)45-51 PMCID:PMC4237627
    • Fouladi M, Perentesis JP, Phillips CL, Leary S, Reid JM, McGovern RM, Ingle AM, Ahern CH, Ames MM, Houghton P, Doyle LA, Weigel B, Blaney SM
      A phase I trial of MK-2206 in children with refractory malignancies: a Children's Oncology Group study.
      24664955 Pediatric blood & cancer, 2014 July : 61(7)1246-51 PMCID:PMC4456022
    • Fontebasso AM, Papillon-Cavanagh S, Schwartzentruber J, Nikbakht H, Gerges N, Fiset PO, Bechet D, Faury D, De Jay N, Ramkissoon LA, Corcoran A, Jones DT, Sturm D, Johann P, Tomita T, Goldman S, Nagib M, Bendel A, Goumnerova L, Bowers DC, Leonard JR, Rubin JB, Alden T, Browd S, Geyer JR, Leary S, Jallo G, Cohen K, Gupta N, Prados MD, Carret AS, Ellezam B, Crevier L, Klekner A, Bognar L, Hauser P, Garami M, Myseros J, Dong Z, Siegel PM, Malkin H, Ligon AH, Albrecht S, Pfister SM, Ligon KL, Majewski J, Jabado N, Kieran MW
      Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
      24705250 Nature genetics, 2014 May : 46(5)462-6 PMCID:PMC4282994
    • Leary PJ, Harris Nolley SJ, Ralph DD, Leary SE
      Elevated pulmonary pressure in survivors of pediatric cancer: a physiologic finding, not a specific disease.
      23816966 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013 Aug 1 : 31(22)2833-4
    • Leary SE, Wozniak AW, Billups CA, Wu J, McPherson V, Neel MD, Rao BN, Daw NC
      Survival of pediatric patients after relapsed osteosarcoma: the St. Jude Children's Research Hospital experience.
      23625626 Cancer, 2013 Jul 15 : 119(14)2645-53 PMCID:PMC4273500
    • Yang T, Temkin N, Barber J, Geyer JR, Leary S, Browd S, Ojemann JG, Ellenbogen RG
      Gross total resection correlates with long-term survival in pediatric patients with glioblastoma.
      23017588 World neurosurgery, 2013 March : 79(3-4)537-44
    • Leary PJ, Leary SE, Stout KK, Schwartz SM, Easterling TR
      Maternal, perinatal, and postneonatal outcomes in women with chronic heart disease in Washington State.
      23168751 Obstetrics and gynecology, 2012 Dec. : 120(6)1283-90 PMCID:PMC4113683
    • Ojemann JG, Hersonskey TY, Abeshaus S, Geyer JR, Saneto RP, Novotny EJ, Kollros P, Leary S, Holmes MD
      Epilepsy surgery after treatment of pediatric malignant brain tumors.
      22835666 Seizure, 2012 Oct. : 21(8)624-30
    • Kelly JP, Leary S, Khanna P, Weiss AH
      Longitudinal measures of visual function, tumor volume, and prediction of visual outcomes after treatment of optic pathway gliomas.
      22364864 Ophthalmology, 2012 June : 119(6)1231-7
    • Leary SE, Olson JM
      The molecular classification of medulloblastoma: driving the next generation clinical trials.
      22189395 Current opinion in pediatrics, 2012 Feb. : 24(1)33-9 PMCID:PMC3348176
    • Pounds S, Gao CL, Johnson RA, Wright KD, Poppleton H, Finkelstein D, Leary SE, Gilbertson RJ
      A procedure to statistically evaluate agreement of differential expression for cross-species genomics.
      21697127 Bioinformatics (Oxford, England), 2011 Aug 1 : 27(15)2098-103 PMCID:PMC3137228
    • Leary SE, Zhou T, Holmes E, Geyer JR, Miller DC
      Histology predicts a favorable outcome in young children with desmoplastic medulloblastoma: a report from the children's oncology group.
      21246528 Cancer, 2011 Jul 15 : 117(14)3262-7 PMCID:PMC3119763
    • Johnson RA, Wright KD, Poppleton H, Mohankumar KM, Finkelstein D, Pounds SB, Rand V, Leary SE, White E, Eden C, Hogg T, Northcott P, Mack S, Neale G, Wang YD, Coyle B, Atkinson J, DeWire M, Kranenburg TA, Gillespie Y, Allen JC, Merchant T, Boop FA, Sanford RA, Gajjar A, Ellison DW, Taylor MD, Grundy RG, Gilbertson RJ
      Cross-species genomics matches driver mutations and cell compartments to model ependymoma.
      20639864 Nature, 2010 Jul 29 : 466(7306)632-6 PMCID:PMC2912966
    • Leary SE, Harrod VL, de Alarcon PA, Reiss UM
      Low-dose systemic thrombolytic therapy for deep vein thrombosis in pediatric patients.
      20118811 Journal of pediatric hematology/oncology, 2010 March : 32(2)97-102 PMCID:PMC3482506


Board Certification(s)

Pediatric Hematology-Oncology

Medical/Professional School

University of Tennessee Health Science Center, Memphis, TN


Johns Hopkins Hospital, Baltimore, MD


St. Jude Children's Research Hospital, Memphis, TN

Clinical Interests

Pediatric brain tumors, Precision Medicine 

Research Focus Area

Novel Therapeutics, Translational Research