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Current Research Studies

APEC14B1, The Project: EveryChild Protocol: A Registry, Eligibility Screening, Biology and Outcome Study

APEC14B1

  • Condition(s): Hodgkin Lymphoma, Other, Malignant Bone Tumors, Clear Cell Sarcoma of the Kidney, Biology, Non-Hodgkin Lymphoma (NHL), Non-rhabdomyosarcoma Soft Tissue Sarcomas, Anaplastic Large Cell Lymphoma (ALCL), Atypical Teratoid/Rhabdoid Tumor, Adrenocortical Carcinoma, Leukemia & Lymphoma, Medulloblastoma, Pilocytic Astrocytoma, Solid Tumor, Chronic Myelogenous Leukemia (CML), Adrenal Tumors, Acute Myeloid Leukemia (AML), Diffuse Large B-cell Lymphoma (DLBCL), Thyroid Cancer, Craniopharyngioma, Acute Lymphoblastic Leukemia (ALL), CNS Sarcoma, Hepatoblastoma, Osteosarcoma, Neuroblastoma, Renal Cell Carcinoma, Recurrent and/or Refractory, Diffuse Intrinsic Pontine Glioma (DIPG), Rhabdomyosarcoma, Germ Cell Tumors, Rhabdoid Tumor of the Kidney, Histiocytic Tumors, Diffuse Midline Glioma (DMG), Hepatocellular Carcinoma, Low-Grade Glioma, Langerhans Cell Histiocytosis (LCH), CNS Embryonal Tumors, Registry, Ewing Sarcoma, Choroid Plexus Tumors, Pheochromocytoma, Wilms Tumor, Brain Tumor, Retinoblastoma, Infant Leukemia, Glioneuronal and Neuronal Tumors, Juvenile Xanthogranuloma (JXG), Newly diagnosed, CNS Germ Cell Tumors, Soft Tissue Sarcomas, Ependymoma, Liver Tumors, Lymphoblastic Lymphoma (LBL), High-Grade Glioma, Renal Tumors, Burkitt's Lymphoma
  • Phase: N/A
  • Clinicaltrials.gov ID: NCT02402244

What is the goal of the study?

The next generation of therapy for childhood cancers will be based upon in-depth molecular phenotyping that may facilitate the development of rational risk-adapted and target-based therapies. In order to support current and future molecularly-guided therapeutic trials and the basic science discovery efforts that will lead to more effective therapies, prevention, early detection and a reduction in early and late-onset toxicities, it is critical to implement universal, high-quality collection of annotated biospecimens from children with cancer. This protocol provides for the collection of biospecimens and accompanying demographic, epidemiologic, therapeutic, and outcome data from all children diagnosed with cancer at participating COG institutions, independent of the patient’s enrollment on a therapeutic clinical trial. Through this approach, the correlation of phenotypic and genotypic or other –omic data with the relevant outcomes at the individual, disease, and protocol levels will be ensured. Biospecimen requirements and handling may be disease specific and thus a detailed manual of procedures will provide disease specific information regarding sample collection and processing based on the clinical diagnosis.

Who can participate in the study?

Please contact the study team listed below to learn more.

Study Team: