Current Research Studies

An Open Label, Single Cohort Study to Assess the Pharmacokinetic Profile of Nusinersen (BIIB058) Administered via the ThecaFlex DRx™ System (PIERRE-PK)

SMA_Pierre_PK

  • Condition(s): Other
  • Phase: I
  • Clinicaltrials.gov ID: NCT06555419

What is the goal of the study?

The purpose of this study is to measure and compare the plasma PK profile of 12 mg nusinersen delivered via the ThecaFlex DRx system with the plasma PK profile of 12 mg nusinersen delivered via LP. This data will help determine if an implantable SC port and IT catheter system can be used as an alternative to LP as a method of IT nusinersen delivery.

Who can participate in the study?

Please contact the study team listed below to learn more.

Study Team: