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Informational Alert

Due to a measles case in the community, please call before coming to Seattle Children’s if you or your child has potential measles symptoms.

High Priority Alert

Masking and Visitation Changes: Due to high rates of respiratory illnesses in our community, we’ve made changes to our masking and visitation guidelines .

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Current Research Studies

A PHASE II RANDOMIZED, MULTICENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY EVALUATING EFFECT OF GLCNAC ON TEAR PRODUCTION IN INDIVIDUALS WITH NGLY1-CDDG

NGLY-1 Trial

What is the goal of the study?

Patients with NGLY1-CDDG will be randomly assigned in a 1:1 ratio to receive either N-acetylglucosamine (GlcNAc) or placebo 3 times per day for 6 weeks. The primary efficacy endpoint is change in tear production between baseline and 6 weeks as measured by the Schirmer II test.

Who can participate in the study?

Please contact the study team listed below to learn more.

Study Team: