Due to a measles case in the community, please call before coming to Seattle Children’s if you or your child has potential measles symptoms.

Masking and Visitation Changes: Due to high rates of respiratory illnesses in our community, we’ve made changes to our masking and visitation guidelines .

Current Research Studies

A Phase II Randomized Controlled Trial Comparing GVHD-Reduction Strategies for Allogeneic Peripheral Blood Transplantation (PBSCT) for Patients with Acute Leukemia or Myelodysplastic Syndrome: Selective Depletion of CD45RA+ Naïve T Cells (TND) vs. Post-Transplantation Cyclophosphamide (PTCy)

9749 GVHD Reduction Strategies

Condition(s): BMT
Phase: II
Clinicaltrials.gov ID: NCT03970096

What is the goal of the study?

This Phase II prospective trial will compare PBSCT with (Arm A) TND, tacrolimus and methotrexate to (Arm C) PTCy for the treatment of patients with high-risk acute leukemia or MDS who require HCT for consolidation of remission.

Who can participate in the study?

Please contact the study team listed below to learn more.

Study Team:

PI (Study Doctor): Marie Bleakley
Study Team Member: Heather Persinger, [email protected]