Fisher BS, Dambrauskas N, Trakhimets O, Andrade DV, Smedley J, Sodora DL, Sather DN.
Oral Immunization with HIV-1 Envelope SOSIP trimers elicits systemic immune responses and cross-reactive anti-V1V2 antibodies in non-human primates.PLoS One, 2020 May 29 : 15(5)e0233577
PMCID:PMC7259690https://pmlegacy.ncbi.nlm.nih.gov/pubmed/32470041
Wood MP, Wood LF, Templeton M, Fisher B, Lippy A, Jones CI, Lindestam Arlehamn CS, Sette A, Fuller JT, Murapa P, Jaspan HB, Fuller DH, Sodora DL.
Transient Immune Activation in BCG-Vaccinated Infant Rhesus Macaques Is Not Sufficient to Influence Oral Simian Immunodeficiency Virus Infection. J Infect Dis., 2019 Oct. 12 : jiz382
https://pubmed.ncbi.nlm.nih.gov/31605528/
Mavigner M, Habib J, Deleage C, Rosen E, Mattingly C, Bricker K, Kashuba A, Amblard F, Schinazi RF, Lawson B, Vanderford TH, Jean S, Cohen J, McGary C, Paiardini M, Wood MP, Sodora DL, Silvestri G, Estes J, Chahroudi A.
Correction for Mavigner et al., "Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques".30655382
J Virol., 2019 Jan. 17 : 93(3)
PMCID:PMC6340051https://www.ncbi.nlm.nih.gov/pubmed/30655382
Wood LF, Brown BP, Lennard K, Karaoz U, Havyarimana E, Passmore JS, Hesseling AC, Edlefsen PT, Kuhn L, Mulder N, Brodie EL, Sodora DL, Jaspan HB.
Feeding-Related Gut Microbial Composition Associates With Peripheral T-Cell Activation and Mucosal Gene Expression in African Infants.29659737
Clin Infect Dis., 2018 Sept. 28 : 67(8)1237-1246
PMCID:PMC6455922https://www.ncbi.nlm.nih.gov/pubmed/29659737
Mavigner M, Habib J, Deleage C, Rosen E, Mattingly C, Bricker K, Kashuba A, Amblard F, Schinazi RF, Lawson B, Vanderford TH, Jean S, Cohen J, McGary C, Paiardini M, Wood MP, Sodora DL, Silvestri G, Estes J, Chahroudi A.
Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques.29997216
J Virol., 2018 Aug. 29 : 92(18)
PMCID:PMC6146711https://www.ncbi.nlm.nih.gov/pubmed/29997216
Fisher BS, Green RR, Brown RR, Wood MP, Hensley-McBain T, Fisher C, Chang J, Miller AD, Bosche WJ, Lifson JD, Mavigner M, Miller CJ, Gale M Jr., Silvestri G, Chahroudi A, Klatt NR, Sodora DL.
Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART.PLoS Pathog, 2018 Feb. 21 : 14(2)e1006871
PMCID:PMC5837102https://www.ncbi.nlm.nih.gov/pubmed/29466439
Palesch D, Bosinger SE, Tharp GK, Vanderford TH, Paiardini M, Chahroudi A, Johnson ZP, Kirchhoff F, Hahn BH, Norgren RB Jr., Patel NB, Sodora DL, Dawoud RA, Harris RA, Liu Y, Raveendran M, Han Y, English A, Thomas GWC, Hahn MW, Pipes L, Mason CE, Muzny DM, Gibbs RA, Sauter D, Worley K, Rogers J, Silvestri G.
Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host.Nature., 2018 Jan. 3 : 553(7686)77-81
PMCID:PMC5843367https://www.ncbi.nlm.nih.gov/pubmed/29300007
Wood LF, Wood M, Fisher B, Jaspan HB, Sodora DL.
T Cell Activation in South African HIV-Exposed Infants Correlates with Ochratoxin-A Exposure. Front Immunol., 2017 Dec. 22 : 81857
PMCID:PMC5743911https://www.ncbi.nlm.nih.gov/pubmed/29312338
Steele AK, Carrasco-Medina L, Sodora DL, Crawley AM.
Increased soluble IL-7 receptor concentrations associate with improved IL-7 therapy outcomes in SIV-infected ART-treated Rhesus macaques.PLoS One, 2017 Dec. 19 : 12(12)e0188427
PMCID:PMC5736176https://www.ncbi.nlm.nih.gov/pubmed/29261677
Gasper MA, Hesseling AC, Mohar I, Myer L, Azenkot T, Passmore JS, Hanekom W, Cotton MF, Crispe IN, Sodora DL, and Jaspan, HB.
BCG vaccination induces HIV target cell activation in HIV-exposed infants in a randomized trial. JCI Insight, 2017 April 6 : 2(7)e91963
PMCID:PMC5374072https://www.ncbi.nlm.nih.gov/pubmed/28405623
Gasper MA, Biswas SP, Fisher BS, Ehnert SC, Sherman DR, Sodora DL.
Non-pathogenic SIV and pathogenic HIV infections associate with disparate innate cytokine signatures in response to Mycobacteria bovis BCG. PLoS One, 2016 Aug. 9 : 11(8)e0158149
PMCID:PMC4978473https://www.ncbi.nlm.nih.gov/pubmed/27505158
Mir KD, Mavigner M, Wang C, Paiardini M, Sodora DL, Chahroudi AM, Bosinger SM, Silvestri G.
Reduced SIV replication in macrophages of sooty mangabeys is associated with increased expression of host restriction factors. J Virol, 2015 Oct. : 89(20)10136-44
PMCID:PMC4580171https://www.ncbi.nlm.nih.gov/pubmed/26202248
Blakney AK, Tchakoute CT, Hesseling AC, Kidzeru EB, Jones CE, Passmore JS, Sodora DL, Gray CM, Jaspan HB.
Delayed BCG vaccination results in minimal alterations in T cell immunogenicity of acellular pertussis and tetanus immunizations in HIV-exposed infants. Vaccine, 2015 Sept. 11 : 33(38)4782-9
PMCID:PMC4562895https://www.ncbi.nlm.nih.gov/pubmed/26259542
Kilgore KM, Murphy MK, Burton SL, Wetzel KS, Smith SA, Xiao P, Reddy S, Francella N, Sodora DL, Silvestri G, Cole KS, Villinger F, Robinson JE, Pulendran B, Hunter E, Collman RG, Amara RR, Derdeyn CA.
Characterization and Implementation of a Diverse Simian Immunodeficiency Virus SIVsm Envelope Panel in the Assessment of Neutralizing Antibody Breadth Elicited in Rhesus Macaques by Multimodal Vaccines Expressing the SIVmac239 Envelope.J Virol, 2015 Aug. : 89(16)8130-51
PMCID:PMC4524250https://www.ncbi.nlm.nih.gov/pubmed/26018167
Tchakoute CT, Hesseling AC, Kidzeru EB, Gamieldien H, Passmore JA, Jones CE, Gray CM, Sodora DL, Jaspan HB.
Delaying BCG vaccination until 8 weeks of age results in robust BCG-Specific T-cell Responses in HIV-exposed infants. J Infect Dis, 2015 Feb. 1 : 211(3)338-46
PMCID:PMC4318913https://www.ncbi.nlm.nih.gov/pubmed/25108027
Kilgore KM, Murphy MK, Wetzel KS, Smith SA, Burton SL, Reddy S, Francella N, Sodora DL, Silvestri G, Cole KS, Villinger F, Robinson JE, Pulendran B, Collman RG, Amara RR, Derdeyn CA.
DNA/MVA and protein-based SIV vaccine regimens delivered to Rhesus macaques with novel adjuvants fail to elicit neutralizing antibodies with breadth. AIDS Res Hum Retrov., 2014 Oct. : 30 Suppl 1A84
Sundaravaradan V, Gasper MA, Mir KD, and Sodora DL.
Lack of chronic immune activation during natural host SIV infection.Natural Hosts of SIV. , 2014 July 25 : 217-233. Ed. Ansari A and Silvestri G.
Kidzeru EB, Hesseling AC, Passmore JA, Myer L, Gamieldien H, Tchakoute CT, Gray CM, Sodora DL, Jaspan HB.
In-utero exposure to maternal HIV infection alters T-cell immune responses to vaccination in HIV-uninfected infants.AIDS, 2014 June 19 : 28(10)1421-30
PMCID:PMC4333196https://www.ncbi.nlm.nih.gov/pubmed/24785950
Gasper MA, Kunwar P, Itaya G, Lejarcegui N, Bosire R, Maleche-Obimbo E, Wamalwa D, Slyker J, Overbaugh J, Horton H, Sodora DL, John-Stewart G, Lohman-Payne B.
Natural killer cell and T-cell subset distributions and activation influence susceptibility to perinatal HIV-1 infection.AIDS, 2014 May 15 : 28(8)1115-24
PMCID:PMC4365995https://www.ncbi.nlm.nih.gov/pubmed/24752082
Schmökel J, Li H, Shabir A, Yu H, Geyer M, Silvestri G, Sodora DL, Hahn BH, Kirchhoff F.
Link between primate lentiviral coreceptor usage and Nef function.Cell Rep, 2013 Nov. 27 : 5(4)997-1009
PMCID:PMC4133736https://www.ncbi.nlm.nih.gov/pubmed/24268781
Milush JM, Chen HL, Atteberry G, Sodora DL.
Early detection of simian immunodeficiency virus in the central nervous system following oral administration to rhesus macaques.Front Immunol, 2013 Aug. 14 : 4236
PMCID:PMC3743037https://www.ncbi.nlm.nih.gov/pubmed/23966995
Sundaravaradan V, Saleem R, Micci L, Gasper MA, Ortiz AM, Else J, Silvestri G, Paiardini M, Aitchison JD, Sodora DL.
Multifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infection.PLoS Pathog, 2013 Aug. : 9(6)e1003441
PMCID:PMC3694849https://www.ncbi.nlm.nih.gov/pubmed/23825945
Wood LF, Chahroudi A, Chen HL, Jaspan HB, Sodora DL.
The oral mucosa immune environment and oral transmission of HIV/SIV.Immunol Rev, 2013 July : 254(1)34-53. Review.
PMCID:PMC3821196https://www.ncbi.nlm.nih.gov/pubmed/23772613
Giavedoni LD, Chen HL, Hodara VL, Chu L, Parodi LM, Smith LM, Sexton V, Cappelli D, Sodora DL.
Impact of mucosal inflammation on oral simian immunodeficiency virus transmission.J Virol, 2013 Feb. : 87(3)1750-8
PMCID:PMC3554177https://www.ncbi.nlm.nih.gov/pubmed/23175379
Mir KD, Bosinger SE, Gasper M, Ho O, Else JG, Brenchley JM, Kelvin DJ, Silvestri G, Hu SL, Sodora DL.
Simian immunodeficiency virus-induced alterations in monocyte production of tumor necrosis factor alpha contribute to reduced immune activation in sooty mangabeys.J Virol, 2012 July : 86(14)7605-15
PMCID:PMC3416282https://www.ncbi.nlm.nih.gov/pubmed/22553338
Sundaravaradan V, Mir KD, Sodora DL.
Double-negative T cells during HIV/SIV infections: potential pinch hitters in the T-cell lineup.Curr Opin HIV AIDS, 2012 March : 7(2)164-71. Review.
PMCID:PMC3639317https://www.ncbi.nlm.nih.gov/pubmed/22241163
Elliott ST, Riddick NE, Francella N, Paiardini M, Vanderford TH, Li B, Apetrei C, Sodora DL, Derdeyn CA, Silvestri G, Collman RG.
Cloning and analysis of sooty mangabey alternative coreceptors that support simian immunodeficiency virus SIVsmm entry independently of CCR5.J Virol, 2012 Jan. : 86(2)898-908
PMCID:PMC3255830https://www.ncbi.nlm.nih.gov/pubmed/22090107
Jaspan HB, Liebenberg L, Hanekom W, Burgers W, Coetzee D, Williamson AL, Little F, Myer L, Coombs RW, Sodora D, Passmore JA.
Immune activation in the female genital tract during HIV infection predicts mucosal CD4 depletion and HIV shedding.21940422
The Journal of infectious diseases, 2011 Nov. 15 : 204(10)1550-6
PMCID:PMC3192190https://www.ncbi.nlm.nih.gov/pubmed/21940422
Bosinger SE, Sodora DL, Silvestri G.
Generalized immune activation and innate immune responses in simian immunodeficiency virus infection.Curr Opin HIV AIDS, 2011 Sept. : 6(5)411-8. Review.
PMCID:PMC3261611https://www.ncbi.nlm.nih.gov/pubmed/21743324
Durudas A, Chen HL, Gasper MA, Sundaravaradan V, Milush JM, Silvestri G, Johnson W, Giavedoni LD, Sodora DL.
Differential innate immune responses to low or high dose oral SIV challenge in Rhesus macaques.Curr HIV Res, 2011 July : 9(5)276-88
PMCID:PMC3337698https://www.ncbi.nlm.nih.gov/pubmed/21861823
Milush JM, Mir KD, Sundaravaradan V, Gordon SN, Engram J, Cano CA, Reeves JD, Anton E, O'Neill E, Butler E, Hancock K, Cole KS, Brenchley JM, Else JG, Silvestri G, Sodora DL.
Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells.J Clin Invest, 2011 March : 121(3)1102-10
PMCID:PMC3049370https://www.ncbi.nlm.nih.gov/pubmed/21317533
Kuhrt D, Faith S, Hattemer A, Leone A, Sodora D, Picker L, Borghesi L, Cole KS.
Naïve and memory B cells in the rhesus macaque can be differentiated by surface expression of CD27 and have differential responses to CD40 ligation.J Immunol Methods, 2011 Jan. 5 : 363(2)166-76
PMCID:PMC3357916https://www.ncbi.nlm.nih.gov/pubmed/20875419
Mir KD, Gasper MA, Sundaravaradan V, Sodora DL.
SIV infection in natural hosts: resolution of immune activation during the acute-to-chronic transition phase.Microbes Infect, 2011 Jan. : 13(1)14-24. Review.
PMCID:PMC3022004https://www.ncbi.nlm.nih.gov/pubmed/20951225
Riddick NE, Hermann EA, Loftin LM, Elliott ST, Wey WC, Cervasi B, Taaffe J, Engram JC, Li B, Else JG, Li Y, Hahn BH, Derdeyn CA, Sodora DL, Apetrei C, Paiardini M, Silvestri G, Collman RG.
A novel CCR5 mutation common in sooty mangabeys reveals SIVsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo.PLoS Pathog, 2010 Aug. 26 : 6(8)e1001064
PMCID:PMC2928783https://www.ncbi.nlm.nih.gov/pubmed/20865163
Engram JC, Cervasi B, Borghans JA, Klatt NR, Gordon SN, Chahroudi A, Else JG, Mittler RS, Sodora DL, de Boer RJ, Brenchley JM, Silvestri G, Paiardini M.
Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates.Blood, 2010 Aug. 5 : 116(5)748-58
PMCID:PMC2918331https://www.ncbi.nlm.nih.gov/pubmed/20484087
Leone A, Rohankhedkar M, Okoye A, Legasse A, Axthelm MK, Villinger F, Piatak M Jr, Lifson JD, Assouline B, Morre M, Picker LJ, Sodora DL.
Increased CD4+ T cell levels during IL-7 administration of antiretroviral therapy-treated simian immunodeficiency virus-positive macaques are not dependent on strong proliferative responses.J Immunol, 2010 : 185(3)1650-9
PMCID:PMC3050806https://www.ncbi.nlm.nih.gov/pubmed/20622118
Harris LD, Tabb B, Sodora DL, Paiardini M, Klatt NR, Douek DC, Silvestri G, Müller-Trutwin M, Vasile-Pandrea I, Apetrei C, Hirsch V, Lifson J, Brenchley JM, Estes JD.
Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques.J Virol, 2010 Aug. : 84(15)7886-91
PMCID:PMC2897601https://www.ncbi.nlm.nih.gov/pubmed/20484518
Li B, Stefano-Cole K, Kuhrt DM, Gordon SN, Else JG, Mulenga J, Allen S, Sodora DL, Silvestri G, Derdeyn CA.
Nonpathogenic simian immunodeficiency virus infection of sooty mangabeys is not associated with high levels of autologous neutralizing antibodies.J Virol, 2010 June : 84(12)6248-53
PMCID:PMC2876631https://www.ncbi.nlm.nih.gov/pubmed/20375163
Sodora DL, Silvestri G.
HIV, mucosal tissues, and T helper 17 cells: where we come from, where we are, and where we go from here.Curr Opin HIV AIDS, 2010 March : 5(2)111-3
https://www.ncbi.nlm.nih.gov/pubmed/20543586
Kuhrt D, Faith SA, Leone A, Rohankedkar M, Sodora DL, Picker LJ, Cole KS.
Evidence of early B-cell dysregulation in simian immunodeficiency virus infection: rapid depletion of naïve and memory B-cell subsets with delayed reconstitution of the naïve B-cell population.J Virol, 2010 March : 84(5)2466-76
PMCID:PMC2820932https://www.ncbi.nlm.nih.gov/pubmed/20032183
Durudas A, Milush JM, Chen HL, Engram JC, Silvestri G, Sodora DL.
Elevated levels of innate immune modulators in lymph nodes and blood are associated with more-rapid disease progression in simian immunodeficiency virus-infected monkeys.J Virol, 2009 Dec. : 83(23)12229-40
PMCID:PMC2786739https://www.ncbi.nlm.nih.gov/pubmed/19759147
Sodora DL, Allan JS, Apetrei C, Brenchley JM, Douek DC, Else JG, Estes JD, Hahn BH, Hirsch VM, Kaur A, Kirchhoff F, Muller-Trutwin M, Pandrea I, Schmitz JE, Silvestri G.
Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts. Nat Med, 2009 Aug. : 15(8)861-5. Review.
PMCID:PMC2782707https://www.ncbi.nlm.nih.gov/pubmed/19661993
Okoye A, Park H, Rohankhedkar M, Coyne-Johnson L, Lum R, Walker JM, Planer SL, Legasse AW, Sylwester AW, Piatak M Jr, Lifson JD, Sodora DL, Villinger F, Axthelm MK, Schmitz JE, Picker LJ.
Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis.J Exp Med, 2009 July 6 : 206(7)1575-88
PMCID:PMC2715089https://www.ncbi.nlm.nih.gov/pubmed/19546246
Paiardini M, Cervasi B, Engram JC, Gordon SN, Klatt NR, Muthukumar A, Else J, Mittler RS, Staprans SI, Sodora DL, Silvestri G.
Bone marrow-based homeostatic proliferation of mature T cells in nonhuman primates: implications for AIDS pathogenesis.Blood, 2009 Jan. 15 : 113(3)612-21
PMCID:PMC2628369https://www.ncbi.nlm.nih.gov/pubmed/18832134
Sodora DL, Ross TM.
Simian immunodeficiency virus pathogenesis.Curr HIV Res, 2009 Jan. : 7(1)1. Commentary.
https://www.ncbi.nlm.nih.gov/pubmed/19149548
Leone A, Picker LJ, Sodora DL.
IL-2, IL-7 and IL-15 as immuno-modulators during SIV/HIV vaccination and treatment.Curr HIV Res, 2009 Jan. : 7(1)83-90. Review.
https://www.ncbi.nlm.nih.gov/pubmed/19149557
Kosub DA, Durudas A, Lehrman G, Milush JM, Cano CA, Jain MK, Sodora DL.
Gamma/Delta T cell mRNA levels decrease at mucosal sites and increase at lymphoid sites following an oral SIV infection of macaques.Curr HIV Res, 2008 Nov. : 6(6)520-30
PMCID:PMC2777980https://www.ncbi.nlm.nih.gov/pubmed/18991617
Pandrea I, Sodora DL, Silvestri G, Apetrei C.
Into the wild: simian immunodeficiency virus (SIV) infection in natural hosts.Trends Immunol, 2008 Sept. : 29(9)419-28. Review.
PMCID:PMC2840226https://www.ncbi.nlm.nih.gov/pubmed/18676179
Schindler M, Schmökel J, Specht A, Li H, Münch J, Khalid M, Sodora DL, Hahn BH, Silvestri G, Kirchhoff F.
Inefficient Nef-mediated downmodulation of CD3 and MHC-I correlates with loss of CD4+T cells in natural SIV infection.PLoS Pathog, 2008 July 18 : 4(7)e1000107
PMCID:PMC2444047https://www.ncbi.nlm.nih.gov/pubmed/18636106
Klatt NR, Villinger F, Bostik P, Gordon SN, Pereira L, Engram JC, Mayne A, Dunham RM, Lawson B, Ratcliffe SJ, Sodora DL, Else J, Reimann K, Staprans SI, Haase AT, Estes JD, Silvestri G, Ansari AA.
Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys.J Clin Invest, 2008 June : 118(6)2039-49
PMCID:PMC2391063https://www.ncbi.nlm.nih.gov/pubmed/18497876
Dunham RM, Cervasi B, Brenchley JM, Albrecht H, Weintrob A, Sumpter B, Engram J, Gordon S, Klatt NR, Frank I, Sodora DL, Douek DC, Paiardini M, Silvestri G.
CD127 and CD25 expression defines CD4+ T cell subsets that are differentially depleted during HIV infection.J Immunol, 2008 April 15 : 180(8)5582-92
PMCID:PMC2683429https://www.ncbi.nlm.nih.gov/pubmed/18390743
Gordon SN, Dunham RM, Engram JC, Estes J, Wang Z, Klatt NR, Paiardini M, Pandrea IV, Apetrei C, Sodora DL, Lee HY, Haase AT, Miller MD, Kaur A, Staprans SI, Perelson AS, Feinberg MB, Silvestri G.
Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis.J Virol, 2008 April : 82(7)3725-35
PMCID:PMC2268472https://www.ncbi.nlm.nih.gov/pubmed/18216113
Sodora DL, Silvestri G.
Immune activation and AIDS pathogenesis.AIDS, 2008 Feb. 19 : 22(4)439-46. Review.
https://www.ncbi.nlm.nih.gov/pubmed/18301056
Kosub DA, Lehrman G, Milush JM, Zhou D, Chacko E, Leone A, Gordon S, Silvestri G, Else JG, Keiser P, Jain MK, Sodora DL.
Gamma/Delta T-cell functional responses differ after pathogenic human immunodeficiency virus and nonpathogenic simian immunodeficiency virus infections.J Virol, 2008 Feb. : 82(3)1155-65
PMCID:PMC2224435https://www.ncbi.nlm.nih.gov/pubmed/18045946
Silvestri G, Paiardini M, Pandrea I, Lederman MM, Sodora DL.
Understanding the benign nature of SIV infection in natural hosts.J Clin Invest, 2007 Nov. : 117(11)3148-54. Review.
PMCID:PMC2045617https://www.ncbi.nlm.nih.gov/pubmed/17975656
Okoye A, Meier-Schellersheim M, Brenchley JM, Hagen SI, Walker JM, Rohankhedkar M, Lum R, Edgar JB, Planer SL, Legasse A, Sylwester AW, Piatak M Jr, Lifson JD, Maino VC, Sodora DL, Douek DC, Axthelm MK, Grossman Z, Picker LJ.
Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection.J Exp Med, 2007 Sept. 3 : 204(9)2171-85
PMCID:PMC2118701https://www.ncbi.nlm.nih.gov/pubmed/17724130
Gordon SN, Klatt NR, Bosinger SE, Brenchley JM, Milush JM, Engram JC, Dunham RM, Paiardini M, Klucking S, Danesh A, Strobert EA, Apetrei C, Pandrea IV, Kelvin D, Douek DC, Staprans SI, Sodora DL, Silvestri G.
Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys.J Immunol, 2007 Sept. 1 : 179(5)3026-34
PMCID:PMC2365740https://www.ncbi.nlm.nih.gov/pubmed/17709517
Milush JM, Reeves JD, Gordon SN, Zhou D, Muthukumar A, Kosub DA, Chacko E, Giavedoni LD, Ibegbu CC, Cole KS, Miamidian JL, Paiardini M, Barry AP, Staprans SI, Silvestri G, Sodora DL.
Virally induced CD4+ T cell depletion is not sufficient to induce AIDS in a natural host.J Immunol, 2007 Sept. 1 : 179(5)3047-56
https://www.ncbi.nlm.nih.gov/pubmed/17709519
Apetrei C, Gautam R, Sumpter B, Carter AC, Gaufin T, Staprans SI, Else J, Barnes M, Cao R Jr, Garg S, Milush JM, Sodora DL, Pandrea I, Silvestri G.
Virus subtype-specific features of natural simian immunodeficiency virus SIVsmm infection in sooty mangabeys.J Virol, 2007 Aug. : 81(15)7913-23
PMCID:PMC1951324https://www.ncbi.nlm.nih.gov/pubmed/17507488
Milush JM, Stefano-Cole K, Schmidt K, Durudas A, Pandrea I, Sodora DL.
Mucosal innate immune response associated with a timely humoral immune response and slower disease progression after oral transmission of simian immunodeficiency virus to rhesus macaques.J Virol, 2007 June : 81(12)6175-86
PMCID:PMC1900075https://www.ncbi.nlm.nih.gov/pubmed/17428863
Estes JD, Wietgrefe S, Schacker T, Southern P, Beilman G, Reilly C, Milush JM, Lifson JD, Sodora DL, Carlis JV, Haase AT.
Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection.J Infect Dis, 2007 Feb. 15 : 195(4)551-61
https://www.ncbi.nlm.nih.gov/pubmed/17230415
Sumpter B, Dunham R, Gordon S, Engram J, Hennessy M, Kinter A, Paiardini M, Cervasi B, Klatt N, McClure H, Milush JM, Staprans S, Sodora DL, Silvestri G.
Correlates of preserved CD4(+) T cell homeostasis during natural, nonpathogenic simian immunodeficiency virus infection of sooty mangabeys: implications for AIDS pathogenesis.J Immunol, 2007 Feb. 1 : 178(3)1680-91
https://www.ncbi.nlm.nih.gov/pubmed/17237418
Levine B, Sodora DL.
HIV and CXCR4 in a kiss of autophagic death.J Clin Invest, 2006 Aug. : 116(8)2078-80
PMCID:PMC1523409https://www.ncbi.nlm.nih.gov/pubmed/16886053
Dunham R, Pagliardini P, Gordon S, Sumpter B, Engram J, Moanna A, Paiardini M, Mandl JN, Lawson B, Garg S, McClure HM, Xu YX, Ibegbu C, Easley K, Katz N, Pandrea I, Apetrei C, Sodora DL, Staprans SI, Feinberg MB, Silvestri G.
The AIDS resistance of naturally SIV-infected sooty mangabeys is independent of cellular immunity to the virus.Blood, 2006 July 1 : 108(1)209-17
PMCID:PMC1895834https://www.ncbi.nlm.nih.gov/pubmed/16522814
Schindler M, Münch J, Kutsch O, Li H, Santiago ML, Bibollet-Ruche F, Müller-Trutwin MC, Novembre FJ, Peeters M, Courgnaud V, Bailes E, Roques P, Sodora DL, Silvestri G, Sharp PM, Hahn BH, Kirchhoff F.
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1.Cell, 2006 June 16 : 125(6)1055-67
https://www.ncbi.nlm.nih.gov/pubmed/16777597
Paiardini M, Cervasi B, Sumpter B, McClure HM, Sodora DL, Magnani M, Staprans SI, Piedimonte G, Silvestri G.
Perturbations of cell cycle control in T cells contribute to the different outcomes of simian immunodeficiency virus infection in rhesus macaques and sooty mangabeys.J Virol, 2006 Jan. : 80(2)634-42
PMCID:PMC1346860https://www.ncbi.nlm.nih.gov/pubmed/16378966
Muthukumar A, Zhou D, Paiardini M, Barry AP, Cole KS, McClure HM, Staprans SI, Silvestri G, Sodora DL.
Timely triggering of homeostatic mechanisms involved in the regulation of T-cell levels in SIVsm-infected sooty mangabeys.Blood, 2005 Dec. 1 : 106(12)3839-45
PMCID:PMC1895113https://www.ncbi.nlm.nih.gov/pubmed/16105985
Paiardini M, Cervasi B, Albrecht H, Muthukumar A, Dunham R, Gordon S, Radziewicz H, Piedimonte G, Magnani M, Montroni M, Kaech SM, Weintrob A, Altman JD, Sodora DL, Feinberg MB, Silvestri G.
Loss of CD127 expression defines an expansion of effector CD8+ T cells in HIV-infected individuals.J Immunol, 2005 March 1 : 174(5)2900-9
https://www.ncbi.nlm.nih.gov/pubmed/15728501
Milush JM, Kosub D, Marthas M, Schmidt K, Scott F, Wozniakowski A, Brown C, Westmoreland S, Sodora DL.
Rapid dissemination of SIV following oral inoculation.AIDS, 2004 Dec. 3 : 18(18)2371-80
https://www.ncbi.nlm.nih.gov/pubmed/15622313
Ylisastigui L, Coull JJ, Rucker VC, Melander C, Bosch RJ, Brodie SJ, Corey L, Sodora DL, Dervan PB, Margolis DM.
Polyamides reveal a role for repression in latency within resting T cells of HIV-infected donors.J Infect Dis, 2004 Oct. 15 : 190(8)1429-37
https://www.ncbi.nlm.nih.gov/pubmed/15378435
Smith SM, Mefford M, Sodora D, Klase Z, Singh M, Alexander N, Hess D, Marx PA.
Topical estrogen protects against SIV vaginal transmission without evidence of systemic effect.AIDS, 2004 Aug. 20 : 18(12)1637-43
https://www.ncbi.nlm.nih.gov/pubmed/15280774
Van Rompay KK, Singh RP, Brignolo LL, Lawson JR, Schmidt KA, Pahar B, Canfield DR, Tarara RP, Sodora DL, Bischofberger N, Marthas ML.
The clinical benefits of tenofovir for simian immunodeficiency virus-infected macaques are larger than predicted by its effects on standard viral and immunologic parameters.J Acquir Immune Defic Syndr, 2004 Aug. 1 : 36(4)900-14
https://www.ncbi.nlm.nih.gov/pubmed/15220696
Van Rompay KK, Singh RP, Pahar B, Sodora DL, Wingfield C, Lawson JR, Marthas ML, Bischofberger N.
CD8+-cell-mediated suppression of virulent simian immunodeficiency virus during tenofovir treatment.J Virol, 2004 May : 78(10)5324-37
PMCID:PMC400346https://www.ncbi.nlm.nih.gov/pubmed/15113912
Saavedra-Lozano J, Cao Y, Callison J, Sarode R, Sodora D, Edgar J, Hatfield J, Picker L, Peterson D, Ramilo O, Vitetta ES.
An anti-CD45RO immunotoxin kills HIV-latently infected cells from individuals on HAART with little effect on CD8 memory.Proc Natl Acad Sci USA, 2004 Feb. 24 : 101(8)2494-9
PMCID:PMC3566978https://www.ncbi.nlm.nih.gov/pubmed/14983037
Muthukumar A, Wozniakowski A, Gauduin MC, Paiardini M, McClure HM, Johnson RP, Silvestri G, Sodora DL.
Elevated interleukin-7 levels not sufficient to maintain T-cell homeostasis during simian immunodeficiency virus-induced disease progression.Blood, 2004 Feb. 1 : 103(3)973-9
https://www.ncbi.nlm.nih.gov/pubmed/14525780
Wang C, Pflugheber J, Sumpter R Jr, Sodora DL, Hui D, Sen GC, Gale M Jr.
Alpha interferon induces distinct translational control programs to suppress hepatitis C virus RNA replication.J Virol, 2003 April : 77(7)3898-912
PMCID:PMC150642https://www.ncbi.nlm.nih.gov/pubmed/12634350
Silvestri G, Sodora DL, Koup RA, Paiardini M, O'Neil SP, McClure HM, Staprans SI, Feinberg MB.
Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia.Immunity, 2003 March : 18(3)441-52
https://www.ncbi.nlm.nih.gov/pubmed/12648460
Wei BL, Arora VK, Foster JL, Sodora DL, Garcia JV.
In vivo analysis of Nef function.Curr HIV Res, 2003 Jan. : 1(1)41-50. Review.
https://www.ncbi.nlm.nih.gov/pubmed/15043211
Sodora DL, Milush JM, Ware F, Wozniakowski A, Montgomery L, McClure HM, Lackner AA, Marthas M, Hirsch V, Johnson RP, Douek DC, Koup RA.
Decreased levels of recent thymic emigrants in peripheral blood of simian immunodeficiency virus-infected macaques correlate with alterations within the thymus.J Virol, 2002 Oct. : 76(19)9981-90
PMCID:PMC136511https://www.ncbi.nlm.nih.gov/pubmed/12208974
Pflugheber J, Fredericksen B, Sumpter R Jr, Wang C, Ware F, Sodora DL, Gale M Jr.
Regulation of PKR and IRF-1 during hepatitis C virus RNA replication.Proc Natl Acad Sci USA., 2002 April 2 : 99(7)4650-5
PMCID:PMC123702https://www.ncbi.nlm.nih.gov/pubmed/11904369
Sodora DL, Douek DC, Silvestri G, Montgomery L, Rosenzweig M, Igarashi T, Bernacky B, Johnson RP, Feinberg MB, Martin MA, Koup RA.
Quantification of thymic function by measuring T cell receptor excision circles within peripheral blood and lymphoid tissues in monkeys.Eur J Immunol, 2000 April : 30(4)1145-53
https://www.ncbi.nlm.nih.gov/pubmed/10760804
Sodora DL, Sheridan KE, Marx PA, Connor RI.
Immunization with a live, attenuated simian immunodeficiency virus vaccine leads to restriction of viral diversity in Rhesus macaques not protected from pathogenic challenge.J Virol, 1999 May : 73(5)4443-6
PMCID:PMC104226https://www.ncbi.nlm.nih.gov/pubmed/10196343
Sodora DL, Gettie A, Miller CJ, Marx PA.
Vaginal transmission of SIV: assessing infectivity and hormonal influences in macaques inoculated with cell-free and cell-associated viral stocks.AIDS Res Hum Retroviruses., 1998 April : 14 Suppl 1S119-23
https://www.ncbi.nlm.nih.gov/pubmed/9581895
Sodora DL, Lee F, Dailey PJ, Marx PA.
A genetic and viral load analysis of the simian immunodeficiency virus during the acute phase in macaques inoculated by the vaginal route.AIDS Res Hum Retroviruses., 1998 Jan. 20 : 14(2)171-81
https://www.ncbi.nlm.nih.gov/pubmed/9462928
Bachmann MH, Mathiason-Dubard C, Learn GH, Rodrigo AG, Sodora DL, Mazzetti P, Hoover EA, Mullins JI.
Genetic diversity of feline immunodeficiency virus: dual infection, recombination, and distinct evolutionary rates among envelope sequence clades.J Virol., 1997 June : 71(6)4241-53
PMCID:PMC191639https://www.ncbi.nlm.nih.gov/pubmed/9151811
Chen Z, Luckay A, Sodora DL, Telfer P, Reed P, Gettie A, Kanu JM, Sadek RF, Yee J, Ho DD, Zhang L, Marx PA.
Human immunodeficiency virus type 2 (HIV-2) seroprevalence and characterization of a distinct HIV-2 genetic subtype from the natural range of simian immunodeficiency virus-infected sooty mangabeys.J Virol., 1997 May : 71(5)3953-60
PMCID:PMC191547https://www.ncbi.nlm.nih.gov/pubmed/9094672
Sodora DL, Courcelle J, Brojatsch J, Berson A, Wang YC, Dow SW, Hoover EA, Mullins JI.
Analysis of a feline immunodeficiency virus provirus reveals patterns of gene sequence conservation distinct from human immunodeficiency virus type 1.AIDS Res Hum Retroviruses., 1995 April : 11(4)531-3
https://www.ncbi.nlm.nih.gov/pubmed/7632468
Eisenberg RJ, Long D, Sodora DL, Chiang H-Y, Wilcox WC, Abrams WR, Muggeridge MI, and Cohen GH.
Structure and function of glycoprotein D from herpes simplex virus. Frontiers in Virology. , 1994 : 3:43-65. Ed. Becker Y and Darai G.
Sodora DL, Shpaer EG, Kitchell BE, Dow SW, Hoover EA, Mullins JI.
Identification of three feline immunodeficiency virus (FIV) env gene subtypes and comparison of the FIV and human immunodeficiency virus type 1 evolutionary patterns.J Virol., 1994 April : 68(4)2230-8
PMCID:PMC236699https://www.ncbi.nlm.nih.gov/pubmed/8139008
Cohen GH, Muggeridge MI, Long D, Sodora DL, Eisenberg RJ.
Structural and functional studies of herpes simplex virus glycoprotein D.Adv Exp Med Biol., 1992 Jan. : 327217-28. Review.
https://www.ncbi.nlm.nih.gov/pubmed/1338265
Sodora DL, Cohen GH, Muggeridge MI, Eisenberg RJ.
Absence of asparagine-linked oligosaccharides from glycoprotein D of herpes simplex virus type 1 results in a structurally altered but biologically active protein.J Virol., 1991 Aug. : 65(8)4424-31
PMCID:PMC248882https://www.ncbi.nlm.nih.gov/pubmed/1649338
Sodora DL, Eisenberg RJ, Cohen GH.
Characterization of a recombinant herpes simplex virus which expresses a glycoprotein D lacking asparagine-linked oligosaccharides.J Virol., 1991 Aug. : 65(8)4432-41
PMCID:PMC248883https://www.ncbi.nlm.nih.gov/pubmed/1649339
Sodora DL, Cohen GH, Eisenberg RJ.
Influence of asparagine-linked oligosaccharides on antigenicity, processing, and cell surface expression of herpes simplex virus type 1 glycoprotein D.J Virol., 1989 Dec. : 63(12)5184-93
PMCID:PMC251182https://www.ncbi.nlm.nih.gov/pubmed/2555549
Wilcox WC, Long D, Sodora DL, Eisenberg RJ, Cohen GH.
The contribution of cysteine residues to antigenicity and extent of processing of herpes simplex virus type 1 glycoprotein D.J Virol., 1988 June : 62(6)1941-7
PMCID:PMC253277https://www.ncbi.nlm.nih.gov/pubmed/2835498
Cohen GH, Wilcox WC, Sodora DL, Long D, Levin JZ, Eisenberg RJ.
Expression of herpes simplex virus type 1 glycoprotein D deletion mutants in mammalian cells.J Virol., 1988 June : 62(6)1932-40
PMCID:PMC253276https://www.ncbi.nlm.nih.gov/pubmed/2452897