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Carroll P, Faray-Kele MC, Parish T
Identifying vulnerable pathways in Mycobacterium tuberculosis by using a knockdown approach.
21642404 Applied and environmental microbiology, 2011 July : 77(14)5040-3 PMCID:PMC3147394

Davey MS, Lin CY, Roberts GW, Heuston S, Brown AC, Chess JA, Toleman MA, Gahan CG, Hill C, Parish T, Williams JD, Davies SJ, Johnson DW, Topley N, Moser B, Eberl M
Human neutrophil clearance of bacterial pathogens triggers anti-microbial γδ T cell responses in early infection.
21589907 PLoS pathogens, 2011 May : 7(5)e1002040 PMCID:PMC3093373

Muttucumaru DG, Smith DA, McMinn EJ, Reese V, Coler RN, Parish T
Mycobacterium tuberculosis Rv0198c, a putative matrix metalloprotease is involved in pathogenicity.
21216669 Tuberculosis (Edinburgh, Scotland), 2011 March : 91(2)111-6

Driscoll MD, McLean KJ, Cheesman MR, Jowitt TA, Howard M, Carroll P, Parish T, Munro AW
Expression and characterization of Mycobacterium tuberculosis CYP144: common themes and lessons learned in the M. tuberculosis P450 enzyme family.
20621636 Biochimica et biophysica acta, 2011 Jan. : 1814(1)76-87

Roberts G, Vadrevu IS, Madiraju MV, Parish T
Control of CydB and GltA1 expression by the SenX3 RegX3 two component regulatory system of Mycobacterium tuberculosis.
21698211 PloS one, 2011 : 6(6)e21090 PMCID:PMC3116866

Sacco E, Slama N, Bäckbro K, Parish T, Laval F, Daffé M, Eynard N, Quémard A
Revisiting the assignment of Rv0241c to fatty acid synthase type II of Mycobacterium tuberculosis.
20511508 Journal of bacteriology, 2010 Aug. : 192(15)4037-44 PMCID:PMC2916384

Ioerger TR, Feng Y, Ganesula K, Chen X, Dobos KM, Fortune S, Jacobs WR Jr, Mizrahi V, Parish T, Rubin E, Sassetti C, Sacchettini JC
Variation among genome sequences of H37Rv strains of Mycobacterium tuberculosis from multiple laboratories.
20472797 Journal of bacteriology, 2010 July : 192(14)3645-53 PMCID:PMC2897344

Andreu N, Zelmer A, Fletcher T, Elkington PT, Ward TH, Ripoll J, Parish T, Bancroft GJ, Schaible U, Robertson BD, Wiles S
Optimisation of bioluminescent reporters for use with mycobacteria.
20520722 PloS one, 2010 May 24 : 5(5)e10777 PMCID:PMC2875389

Brown AC, Eberl M, Crick DC, Jomaa H, Parish T
The nonmevalonate pathway of isoprenoid biosynthesis in Mycobacterium tuberculosis is essential and transcriptionally regulated by Dxs.
20172995 Journal of bacteriology, 2010 May : 192(9)2424-33 PMCID:PMC2863480

Carroll P, Schreuder LJ, Muwanguzi-Karugaba J, Wiles S, Robertson BD, Ripoll J, Ward TH, Bancroft GJ, Schaible UE, Parish T
Sensitive detection of gene expression in mycobacteria under replicating and non-replicating conditions using optimized far-red reporters.
20352111 PloS one, 2010 March 23 : 5(3)e9823 PMCID:PMC2843721

Movahedzadeh F, Wheeler PR, Dinadayala P, Av-Gay Y, Parish T, Daffé M, Stoker NG
Inositol monophosphate phosphatase genes of Mycobacterium tuberculosis.
20167072 BMC microbiology, 2010 Feb. 18 : 1050 PMCID:PMC2834668

Eoh H, Narayanasamy P, Brown AC, Parish T, Brennan PJ, Crick DC
Expression and characterization of soluble 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from bacterial pathogens.
20064433 Chemistry & biology, 2009 Dec. 24 : 16(12)1230-9 PMCID:PMC4020808

Goude R, Amin AG, Chatterjee D, Parish T
The arabinosyltransferase EmbC is inhibited by ethambutol in Mycobacterium tuberculosis.
19596878 Antimicrobial agents and chemotherapy, 2009 Oct. : 53(10)4138-46 PMCID:PMC2764220

McLean KJ, Carroll P, Lewis DG, Dunford AJ, Seward HE, Neeli R, Cheesman MR, Marsollier L, Douglas P, Smith WE, Rosenkrands I, Cole ST, Leys D, Parish T, Munro AW
Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv.
18818197 The Journal of biological chemistry, 2008 Nov. 28 : 283(48)33406-16 PMCID:PMC2662266

Covarrubias AS, Högbom M, Bergfors T, Carroll P, Mannerstedt K, Oscarson S, Parish T, Jones TA, Mowbray SL
Structural, biochemical, and in vivo investigations of the threonine synthase from Mycobacterium tuberculosis.
18621388 Journal of molecular biology, 2008 Sept. 5 : 381(3)622-33

Movahedzadeh F, Williams A, Clark S, Hatch G, Smith D, ten Bokum A, Parish T, Bacon J, Stoker N
Construction of a severely attenuated mutant of Mycobacterium tuberculosis for reducing risk to laboratory workers.
18457997 Tuberculosis (Edinburgh, Scotland), 2008 Sept. : 88(5)375-81

Carroll P, Pashley CA, Parish T
Functional analysis of GlnE, an essential adenylyl transferase in Mycobacterium tuberculosis.
18469098 Journal of bacteriology, 2008 July : 190(14)4894-902 PMCID:PMC2446997

Goude R, Parish T
The genetics of cell wall biosynthesis in Mycobacterium tuberculosis.
18505396 Future microbiology, 2008 June : 3(3)299-313

Goude R, Amin AG, Chatterjee D, Parish T
The critical role of embC in Mycobacterium tuberculosis.
18424526 Journal of bacteriology, 2008 June : 190(12)4335-41 PMCID:PMC2446762

Brown AC, Parish T
Dxr is essential in Mycobacterium tuberculosis and fosmidomycin resistance is due to a lack of uptake.
18489786 BMC microbiology, 2008 May 20 : 878 PMCID:PMC2409342

Schneider CZ, Parish T, Basso LA, Santos DS
The two chorismate mutases from both Mycobacterium tuberculosis and Mycobacterium smegmatis: biochemical analysis and limited regulation of promoter activity by aromatic amino acids.
17965159 Journal of bacteriology, 2008 Jan. : 190(1)122-34 PMCID:PMC2223748

Amin AG, Goude R, Shi L, Zhang J, Chatterjee D, Parish T
EmbA is an essential arabinosyltransferase in Mycobacterium tuberculosis.
18174142 Microbiology (Reading, England), 2008 Jan. : 154(Pt 1)240-248 PMCID:PMC2885622

Eoh H, Brown AC, Buetow L, Hunter WN, Parish T, Kaur D, Brennan PJ, Crick DC
Characterization of the Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol synthase: potential for drug development.
17921290 Journal of bacteriology, 2007 Dec. : 189(24)8922-7 PMCID:PMC2168624

Buetow L, Brown AC, Parish T, Hunter WN
The structure of Mycobacteria 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, an essential enzyme, provides a platform for drug discovery.
17956607 BMC structural biology, 2007 Oct. 23 : 768 PMCID:PMC2151065

Sacco E, Covarrubias AS, O'Hare HM, Carroll P, Eynard N, Jones TA, Parish T, Daffé M, Bäckbro K, Quémard A
The missing piece of the type II fatty acid synthase system from Mycobacterium tuberculosis.
17804795 Proceedings of the National Academy of Sciences of the United States of America, 2007 Sept. 11 : 104(37)14628-33 PMCID:PMC1976197

Robertson D, Carroll P, Parish T
Rapid recombination screening to test gene essentiality demonstrates that pyrH is essential in Mycobacterium tuberculosis.
17719852 Tuberculosis (Edinburgh, Scotland), 2007 Sept. : 87(5)450-8

Carroll P, Brown AC, Hartridge AR, Parish T
Expression of Mycobacterium tuberculosis Rv1991c using an arabinose-inducible promoter demonstrates its role as a toxin.
17623030 FEMS microbiology letters, 2007 Sept. : 274(1)73-82

Read R, Pashley CA, Smith D, Parish T
The role of GlnD in ammonia assimilation in Mycobacterium tuberculosis.
17303474 Tuberculosis (Edinburgh, Scotland), 2007 July : 87(4)384-90 PMCID:PMC1913930

Parish T, Roberts G, Laval F, Schaeffer M, Daffé M, Duncan K
Functional complementation of the essential gene fabG1 of Mycobacterium tuberculosis by Mycobacterium smegmatis fabG but not Escherichia coli fabG.
17337570 Journal of bacteriology, 2007 May : 189(10)3721-8 PMCID:PMC1913321

Pashley CA, Brown AC, Robertson D, Parish T
Identification of the Mycobacterium tuberculosis GlnE promoter and its response to nitrogen availability.
16946267 Microbiology (Reading, England), 2006 Sept. : 152(Pt 9)2727-2734

Brown AC, Parish T
Instability of the acetamide-inducible expression vector pJAM2 in Mycobacterium tuberculosis.
16125237 Plasmid, 2006 Jan. : 55(1)81-6

Carroll P, Muttucumaru DG, Parish T
Use of a tetracycline-inducible system for conditional expression in Mycobacterium tuberculosis and Mycobacterium smegmatis.
15933004 Applied and environmental microbiology, 2005 June : 71(6)3077-84 PMCID:PMC1151860

Parish T, Schaeffer M, Roberts G, Duncan K
HemZ is essential for heme biosynthesis in Mycobacterium tuberculosis.
15850757 Tuberculosis (Edinburgh, Scotland), 2005 May : 85(3)197-204

Wheeler PR, Coldham NG, Keating L, Gordon SV, Wooff EE, Parish T, Hewinson RG
Functional demonstration of reverse transsulfuration in the Mycobacterium tuberculosis complex reveals that methionine is the preferred sulfur source for pathogenic Mycobacteria.
15576367 The Journal of biological chemistry, 2005 March 4 : 280(9)8069-78

Williams A, Hatch GJ, Clark SO, Gooch KE, Hatch KA, Hall GA, Huygen K, Ottenhoff TH, Franken KL, Andersen P, Doherty TM, Kaufmann SH, Grode L, Seiler P, Martin C, Gicquel B, Cole ST, Brodin P, Pym AS, Dalemans W, Cohen J, Lobet Y, Goonetilleke N, McShane H, Hill A, Parish T, Smith D, Stoker NG, Lowrie DB, Källenius G, Svenson S, Pawlowski A, Blake K, Marsh PD
Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis.
15687025 Tuberculosis (Edinburgh, Scotland), 2005 Jan. : 85(1-2)29-38

Bhakta S, Besra GS, Upton AM, Parish T, Sholto-Douglas-Vernon C, Gibson KJ, Knutton S, Gordon S, DaSilva RP, Anderton MC, Sim E
Arylamine N-acetyltransferase is required for synthesis of mycolic acids and complex lipids in Mycobacterium bovis BCG and represents a novel drug target.
15117974 The Journal of experimental medicine, 2004 May 3 : 199(9)1191-9 PMCID:PMC2211905

Kendall SL, Movahedzadeh F, Rison SC, Wernisch L, Parish T, Duncan K, Betts JC, Stoker NG
The Mycobacterium tuberculosis dosRS two-component system is induced by multiple stresses.
15207494 Tuberculosis (Edinburgh, Scotland), 2004 : 84(3-4)247-55

Muttucumaru DG, Roberts G, Hinds J, Stabler RA, Parish T
Gene expression profile of Mycobacterium tuberculosis in a non-replicating state.
15207493 Tuberculosis (Edinburgh, Scotland), 2004 : 84(3-4)239-46

Pashley CA, Parish T
Efficient switching of mycobacteriophage L5-based integrating plasmids in Mycobacterium tuberculosis.
14680701 FEMS microbiology letters, 2003 Dec. 12 : 229(2)211-5

Parish T
Starvation survival response of Mycobacterium tuberculosis.
14594845 Journal of bacteriology, 2003 Nov. : 185(22)6702-6 PMCID:PMC262115

Parish T, Smith DA, Roberts G, Betts J, Stoker NG
The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence.
12777483 Microbiology (Reading, England), 2003 June : 149(Pt 6)1423-1435

Roberts G, Muttucumaru DG, Parish T
Control of the acetamidase gene of Mycobacterium smegmatis by multiple regulators.
12694921 FEMS microbiology letters, 2003 April 11 : 221(1)131-6

Parish T, Smith DA, Kendall S, Casali N, Bancroft GJ, Stoker NG
Deletion of two-component regulatory systems increases the virulence of Mycobacterium tuberculosis.
12595424 Infection and immunity, 2003 March : 71(3)1134-40 PMCID:PMC148821

Pashley CA, Parish T, McAdam RA, Duncan K, Stoker NG
Gene replacement in mycobacteria by using incompatible plasmids.
12514036 Applied and environmental microbiology, 2003 Jan. : 69(1)517-23 PMCID:PMC152386

Wernisch L, Kendall SL, Soneji S, Wietzorrek A, Parish T, Hinds J, Butcher PD, Stoker NG
Analysis of whole-genome microarray replicates using mixed models.
12499293 Bioinformatics (Oxford, England), 2003 Jan. : 19(1)53-61

Greendyke R, Rajagopalan M, Parish T, Madiraju MVVS
Conditional expression of Mycobacterium smegmatis dnaA, an essential DNA replication gene.
12480893 Microbiology (Reading, England), 2002 Dec. : 148(Pt 12)3887-3900

Parish T, Stoker NG
The common aromatic amino acid biosynthesis pathway is essential in Mycobacterium tuberculosis.
12368440 Microbiology (Reading, England), 2002 Oct. : 148(Pt 10)3069-3077

Dziadek J, Rajagopalan M, Parish T, Kurepina N, Greendyke R, Kreiswirth BN, Madiraju MV
Mutations in the CCGTTCACA DnaA box of Mycobacterium tuberculosis oriC that abolish replication of oriC plasmids are tolerated on the chromosome.
12081955 Journal of bacteriology, 2002 July : 184(14)3848-55 PMCID:PMC135179

Smith DA, Parish T, Stoker NG, Bancroft GJ
Characterization of auxotrophic mutants of Mycobacterium tuberculosis and their potential as vaccine candidates.
11160012 Infection and immunity, 2001 Feb. : 69(2)1142-50 PMCID:PMC97996

Parish T, Turner J, Stoker NG
amiA is a negative regulator of acetamidase expression in Mycobacterium smegmatis.
11570974 BMC microbiology, 2001 : 119 PMCID:PMC56589

Parish T, Lewis J, Stoker NG
Use of the mycobacteriophage L5 excisionase in Mycobacterium tuberculosis to demonstrate gene essentiality.
11800587 Tuberculosis (Edinburgh, Scotland), 2001 : 81(5-6)359-64

Gordhan BG, Parish T
Gene Replacement using Pretreated DNA.
21341070 Methods in molecular medicine, 2001 : 5477-92

Parish T, Stoker NG
glnE is an essential gene in Mycobacterium tuberculosis.
11004169 Journal of bacteriology, 2000 Oct. : 182(20)5715-20 PMCID:PMC94692

Parish T, Stoker NG
Use of a flexible cassette method to generate a double unmarked Mycobacterium tuberculosis tlyA plcABC mutant by gene replacement.
10931901 Microbiology (Reading, England), 2000 Aug. : 146 ( Pt 81969-1975

Parish T, Gordhan BG, McAdam RA, Duncan K, Mizrahi V, Stoker NG
Production of mutants in amino acid biosynthesis genes of Mycobacterium tuberculosis by homologous recombination.
10627047 Microbiology (Reading, England), 1999 Dec. : 145 ( Pt 13497-3503

Hinds J, Mahenthiralingam E, Kempsell KE, Duncan K, Stokes RW, Parish T, Stoker NG
Enhanced gene replacement in mycobacteria.
10217485 Microbiology (Reading, England), 1999 March : 145 ( Pt 3519-527

Triccas JA, Parish T, Britton WJ, Gicquel B
An inducible expression system permitting the efficient purification of a recombinant antigen from Mycobacterium smegmatis.
9809415 FEMS microbiology letters, 1998 Oct. 15 : 167(2)151-6

McNerney R, Wilson SM, Sidhu AM, Harley VS, al Suwaidi Z, Nye PM, Parish T, Stoker NG
Inactivation of mycobacteriophage D29 using ferrous ammonium sulphate as a tool for the detection of viable Mycobacterium smegmatis and M. tuberculosis.
9766200 Research in microbiology, 1998 July : 149(7)487-95

Wren BW, Stabler RA, Das SS, Butcher PD, Mangan JA, Clarke JD, Casali N, Parish T, Stoker NG
Characterization of a haemolysin from Mycobacterium tuberculosis with homology to a virulence factor of Serpulina hyodysenteriae.
9611795 Microbiology (Reading, England), 1998 May : 144 ( Pt 51205-11

Parish T, Liu J, Nikaido H, Stoker NG
A Mycobacterium smegmatis mutant with a defective inositol monophosphate phosphatase gene homolog has altered cell envelope permeability.
9401044 Journal of bacteriology, 1997 Dec. : 179(24)7827-33 PMCID:PMC179748

Parish T, Stoker NG
Development and use of a conditional antisense mutagenesis system in mycobacteria.
9297833 FEMS microbiology letters, 1997 Sept. 1 : 154(1)151-7

Parish T, Mahenthiralingam E, Draper P, Davis EO, Colston MJ
Regulation of the inducible acetamidase gene of Mycobacterium smegmatis.
9245815 Microbiology (Reading, England), 1997 July : 143 ( Pt 72267-76

Gordon S, Parish T, Roberts IS, Andrew PW
The application of luciferase as a reporter of environmental regulation of gene expression in mycobacteria.
7765445 Letters in applied microbiology, 1994 Nov. : 19(5)336-40

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