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Kumar A, Chettiar S, Brown BS, Early J, Ollinger J, Files M, Bailey MA, Korkegian A, Dennison D, McNeil M, Metz J, Osuma A, Curtin M, Kunzer A, Freiberg G, Bruncko M, Kempf D, Parish T
Novel chemical entities inhibiting Mycobacterium tuberculosis growth identified by phenotypic high-throughput screening.
36050506 Scientific reports, 2022 Sep 1 : 12(1)14879 PMCID:PMC9435431

Galina L, Hopf FSM, Abbadi BL, Sperotto NDM, Czeczot AM, Duque-Villegas MA, Perello MA, Matter LB, de Souza EV, Parish T, Machado P, Basso LA, Bizarro CV
Evaluation of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase (DAHPS) as a Vulnerable Target in Mycobacterium tuberculosis.
35862980 Microbiology spectrum, 2022 Aug 31 : 10(4)e0072822 PMCID:PMC9430761

Gold B, Zhang J, Quezada LL, Roberts J, Ling Y, Wood M, Shinwari W, Goullieux L, Roubert C, Fraisse L, Bacqué E, Lagrange S, Filoche-Rommé B, Vieth M, Hipskind PA, Jungheim LN, Aubé J, Scarry SM, McDonald SL, Li K, Perkowski A, Nguyen Q, Dartois V, Zimmerman M, Olsen DB, Young K, Bonnett S, Joerss D, Parish T, Boshoff HI, Arora K, Barry CE 3rd, Guijarro L, Anca S, Rullas J, Rodríguez-Salguero B, Martínez-Martínez MS, Porras-De Francisco E, Cacho M, Barros-Aguirre D, Smith P, Berthel SJ, Nathan C, Bates RH
Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions.
35192346 ACS infectious diseases, 2022 Mar 11 : 8(3)557-573 PMCID:PMC8922279

Mehdiratta K, Singh S, Sharma S, Bhosale RS, Choudhury R, Masal DP, Manocha A, Dhamale BD, Khan N, Asokachandran V, Sharma P, Ikeh M, Brown AC, Parish T, Ojha AK, Michael JS, Faruq M, Medigeshi GR, Mohanty D, Reddy DS, Natarajan VT, Kamat SS, Gokhale RS
Kupyaphores are zinc homeostatic metallophores required for colonization of Mycobacterium tuberculosis.
35193957 Proceedings of the National Academy of Sciences of the United States of America, 2022 Feb 22 : 119(8) PMCID:PMC8872721

Ahmed S, Manning A, Flint L, Awasthi D, Ovechkina Y, Parish T
Identification of Novel Chemical Scaffolds that Inhibit the Growth of Mycobacterium tuberculosis in Macrophages.
35046812 Frontiers in pharmacology, 2021 : 12790583 PMCID:PMC8762250

Hembre E, Early JV, Odingo J, Shelton C, Anoshchenko O, Guzman J, Flint L, Dennison D, McNeil MB, Korkegian A, Ovechkina Y, Ornstein P, Masquelin T, Hipskind PA, Parish T
Novel Trifluoromethyl Pyrimidinone Compounds With Activity Against Mycobacterium tuberculosis.
33996738 Frontiers in chemistry, 2021 : 9613349 PMCID:PMC8117417

McNeil MB, O'Malley T, Dennison D, Shelton CD, Sunde B, Parish T
Multiple Mutations in Mycobacterium tuberculosis MmpL3 Increase Resistance to MmpL3 Inhibitors.
33055263 mSphere, 2020 Oct 14 : 5(5) PMCID:PMC7565900

Berube BJ, Russell D, Castro L, Choi SR, Narayanasamy P, Parish T
Novel MenA Inhibitors Are Bactericidal against Mycobacterium tuberculosis and Synergize with Electron Transport Chain Inhibitors.
30962346 Antimicrobial agents and chemotherapy, 2019 June : 63(6) PMCID:PMC6535543

Cleghorn LAT, Ray PC, Odingo J, Kumar A, Wescott H, Korkegian A, Masquelin T, Lopez Moure A, Wilson C, Davis S, Huggett M, Turner P, Smith A, Epemolu O, Zuccotto F, Riley J, Scullion P, Shishikura Y, Ferguson L, Rullas J, Guijarro L, Read KD, Green SR, Hipskind P, Parish T, Wyatt PG
Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB.
29944372 Journal of medicinal chemistry, 2018 Aug 9 : 61(15)6592-6608 PMCID:PMC6089501

O'Malley T, Alling T, Early JV, Wescott HA, Kumar A, Moraski GC, Miller MJ, Masquelin T, Hipskind PA, Parish T
Imidazopyridine Compounds Inhibit Mycobacterial Growth by Depleting ATP Levels.
29632008 Antimicrobial agents and chemotherapy, 2018 June : 62(6) PMCID:PMC5971599

Xia Y, Zhou Y, Carter DS, McNeil MB, Choi W, Halladay J, Berry PW, Mao W, Hernandez V, O'Malley T, Korkegian A, Sunde B, Flint L, Woolhiser LK, Scherman MS, Gruppo V, Hastings C, Robertson GT, Ioerger TR, Sacchettini J, Tonge PJ, Lenaerts AJ, Parish T, Alley M
Discovery of a cofactor-independent inhibitor of Mycobacterium tuberculosis InhA.
30456352 Life science alliance, 2018 June : 1(3)e201800025 PMCID:PMC6238539

Melief E, Kokoczka R, Files M, Bailey MA, Alling T, Li H, Ahn J, Misquith A, Korkegian A, Roberts D, Sacchettini J, Parish T
Construction of an overexpression library for Mycobacterium tuberculosis.
30197930 Biology methods & protocols, 2018 : 3(1)bpy009 PMCID:PMC6118195

Odingo J, Bailey MA, Files M, Early JV, Alling T, Dennison D, Bowman J, Dalai S, Kumar N, Cramer J, Masquelin T, Hipskind PA, Parish T
In Vitro Evaluation of Novel Nitazoxanide Derivatives against Mycobacterium tuberculosis.
30023755 ACS omega, 2017 Sep 30 : 2(9)5873-5890 PMCID:PMC6044914

Howell Wescott HA, Roberts DM, Allebach CL, Kokoczka R, Parish T
Imidazoles Induce Reactive Oxygen Species in Mycobacterium tuberculosis Which Is Not Associated with Cell Death.
28180188 ACS omega, 2017 Jan 31 : 2(1)41-51 PMCID:PMC5286457

Chandrasekera NS, Alling T, Bailey MA, Files M, Early JV, Ollinger J, Ovechkina Y, Masquelin T, Desai PV, Cramer JW, Hipskind PA, Odingo JO, Parish T
Identification of Phenoxyalkylbenzimidazoles with Antitubercular Activity.
26295286 Journal of medicinal chemistry, 2015 Sep 24 : 58(18)7273-85