Aderem Lab

Selected Publications

Listed below is a selection of recent publications from the Aderem Lab.

See full list on PubMed

Prospective discrimination of controllers from progressors early after low-dose Mycobacterium tuberculosis infection of cynomolgus macaques using blood RNA signaturesThompson EG, Shankar S, Gideon HP, Braun J, Valvo J, Skinner JA, Aderem A, Flynn JL, Lin PL, Zak DE. J Infect Dis. 2018 Mar 28;217(8):1318-1322.

Four-gene pan-African blood signature predicts progression to tuberculosis. Suliman S, Thompson E, Sutherland J, … Aderem A, et al; and the GC6-74 and ACS cohort study groups. Am J Respir Crit Care Med. 2018 Apr 6.

Reshaping of the dendritic cell chromatin landscape and interferon pathways during HIV infection. Johnson JS, Lucas SY, Amon LM, Skelton S, Nazitto R, Carbonetti S, Sather DN, Littman DR, Aderem A. Cell Host Microbe. 2018 Mar 14;23(3):366-381.e9.

Prevention of tuberculosis in rhesus macaques by a cytomegalovirous-based vaccine. Scott G Hansen, Daniel E. Zak, Gwangwu Xu … Alan Adarem et al. Nature Magazine. 24, 130-143 (2018)

Host blood RNA signatures predict the outcome of tuberculosis treatment. Ethan G Thompson, Ying Du, Stephanus T. Malherbe,Alan Aderem,  et al. Am J Respir Crit Care Med. 2018 Apr 6.

Identifying novel transcription factors involved in the inflammatory response by using binding site motif scanning in genomic regions defined by histone acetylation. Askovich PS, Ramsey SA, Diercks AH, Kennedy KA, Knijnenburg TA, Aderem A. PLoS One. 2017 Sep 18;12(9):e0184850.

miR-144 attenuates the host response to influenza virus by targeting the TRAF6-IRF7 signaling axis. Rosenberger CM, Podyminogin RL, Diercks AH, Treuting PM, Peschon JJ, Rodriguez D, Gundapuneni M, Weiss MJ, Aderem A. PLoS Pathog. 2017 Apr 5;13(4):e1006305.  

Systems analysis of protective immune responses to RTS,S malaria vaccination in humans. Kazmin D, Nakaya HI, Lee EK …  Aderem A, et al. Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2425-2430

MiR-155-regulated molecular network orchestrates cell fate in the innate and adaptive immune response to Mycobacterium tuberculosis. Rothchild AC, Sissons JR, Shafiani S, Plaisier C, Min D, Mai D, Gilchrist M, Peschon J, Larson RP, Bergthaler A, Baliga NS, Urdahl KB, Aderem A. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6172-E6181

A blood RNA signature for tuberculosis disease risk: a prospective cohort study. Zak DE, Penn-Nicholson A, Scriba TJ … Aderem A, Hanekom WA. ACS and GC6-74 cohort study groups. Lancet. 2016 Jun 4;387(10035):2312-2322.