Chronic Recurrent Multifocal Osteomyelitis (CRMO) Research Team
Developing reliable clinical and research outcome measurement tools improving care for chronic recurrent multifocal osteomyelitis
Our research team is highly integrated with the clinical care team for children with chronic recurrent multifocal osteomyelitis (CRMO). Our mission is to understand the mechanism of this rare autoinflammatory bone disease and characterize a highly heterogeneous patient population systematically. Our goal is to develop reliable clinical and research outcome measurement tools and implement them in clinical trials and care. Our team collaborates internationally with families, physicians and researchers to work towards our common mission, a world united for CRMO warriors.
Partnership Opportunities
Yongdong Zhao, MD, PhD, RhMSUS
Dan Zhao is the PI of this highly motivated research team and a leader of the CARRA international workgroup of CNO. He is also a clinician and the director of the CRMO clinical program and the ultrasound program. He and his family enjoy traveling and cooking. He loves to play tennis, table tennis and pickleball. He and his daughter are also horseback riders.
Natalie L Rosenwasser, MD
Natalie Rosenwasser is a pediatric rheumatologist at Seattle Children’s Hospital. She is interested in patient outcomes and mental health in the research space. She is the co-director of the CRMO clinical program and serves as treasurer for the CRMO Warriors Guild. She enjoys exploring the outdoors, Pilates, yoga, travelling with her family and downtime snuggling with her cat.
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Vishya Adipudi
Undergraduate Student
Vishya Adipudi is a senior at the University of Washington studying public health and biochemistry. She contributes to the machine learning and deep learning projects for CRMO imaging. Outside the lab, you can find her hiking, backpacking, camping, volunteering locally, biking and finding Seattle’s best latte.
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Haodong (Daniel) Chen, PhD, MS
PhD Fellow
Daniel Chen works on healthcare AI projects, focusing on CRMO research. Research interests include data wrangling, clustering, computer vision, statistical modeling, multimodal data integration and advanced deep learning architectures such as CNNs, transformers, etc. He also contributes to grant writing and publications. Outside of work, he enjoys hiking, exercising, cooking and exploring new cuisines, parks, botanical gardens and zoos.
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Shripad Guntur
Undergraduate Student
Shripad Guntur is a junior studying bioengineering with a focused interest in the intersection of machine learning and medicine to develop innovative healthcare solutions. Through research experience and clinical work as a medical assistant, he is passionate about leveraging technology to improve patient outcomes and medical diagnostics. Outside the lab, he enjoys snowboarding and car racing, and actively volunteers in the local community through various service initiatives. He brings both technical expertise and a commitment to service to research endeavors, seeking to bridge the gap between engineering innovation and real-world medical applications.
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Jessica Kent, MBA
Medical Student
Jessica Kent holds an MBA from Rice University and is currently a third-year medical student at the Medical College of Wisconsin. Outside of academics, she volunteers as a youth golf coach and serves as a patient mentor for young adults living with rare diseases.
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Ava Klein
CRMO Program Coordinator
Ava Klein helps with the administration of all things CRMO at Seattle Children’s. In the research realm, she assists with the creation and editing of protocols, projects, meetings grants and publications.
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Queenee Li
Undergraduate Student
Queenee is a junior at the University of Washington studying for her BS in bochemistry with an interest in clinical research and medicine. She focuses on clinic chart extractions and REDCap entry for the CHOIR research, as well as isolating data for different projects in the office. Outside of research, she loves to step into nature for hikes and enjoy sports games all around the U.S.
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Natasha Moussouras, MD, PhD
Clinical Rheumatology Fellow
Natasha Moussouras is a pediatric rheumatology fellow at Seattle Children’s/University of Washington, working on developing her clinical research skills with Dr. Zhao and the rest of the CRMO team. Outside of work she enjoys ballet, salsa and all types of dance-based movement, hiking, biking, trying out new restaurants and being outside in lovely Seattle and the Pacific Northwest.
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Ian Muse
CRMO Program Coordinator
Ian Muse supports a wide array of projects as part of CRMO Research and mentors student lab members in the PEDS 499 program. Primarily, Ian works with families in the clinic, takes care of administrative needs behind the scenes and maintains the databases. Outside of work you can find him cycling, doing arts-and-crafts projects and searching for the best deli in Seattle.
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Megan Nguyen
Undergraduate Student
Megan Nguyen is a junior studying public health at the University of Washington and helps with the CHOIR study. She plays basketball during her spare time.
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Scott Sutherland
Scott Sutherland is a sophomore at the University of Washington, studying biochemistry and medical anthropology. At the CRMO Lab he contributes to longitudinal MRI and clinical data entry. Outside of the lab, he enjoys rock climbing, running, backpacking and snowboarding
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Xing Wang, PhD
Biostatistician
Xing Wang has been a biostatistician since 2016, with a PhD in statistics and extensive training in statistical modeling. She devotes herself to assisting investigators by translating statistical findings into clinical insights. Her research interests include generalized linear and mixed models, survival analysis, propensity scores, experimental design and methods for classification, clustering and variable selection in clinical trials and epidemiology.
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Avril WIlson, BS
Master's Student
Avril Wilson is a recent graduate of the University of Washington with a BS in earth and space sciences, concentrating in biology, and is now going into her first year of the University of Washington MPH program in epidemiology. At Seattle Children's, she is currently working on a project led by Daniel Chen working with CNO imaging and machine learning. Outside of the lab, she is a D1 track and field athlete, as well as a biology tutor and owner of an albino corn snake.
Meet Our Collaborators

Libby Murray (parent research partner), fourth from left; Lauren Potts (patient research partner), fifth from left; and Lindsay Bergstrom (parent research partner), third from right. Congratulations to Libby and Lauren for the 2025 CARRA Award! Thank you for your dedicated work!

2025 CARRA CRMO Workgroup

Team building led by Ava for pre-CARRA consensus meeting

Group photo for collaborators at the 2025 Pre-CARRA consensus conference for MDA, Flare and MCID at Denver, Colorado.