The goal of the Vitanza Lab is to find new treatments that are both safe and curative for high-grade, aggressive pediatric brain and spinal cord tumors, such as diffuse intrinsic pontine glioma (DIPG), diffuse midline glioma H3 K27M-mutant (DMG) and atypical teratoid rhabdoid tumor (ATRT). Our lab generates treatment-naïve patient-derived models for our own studies and to share with the international research community. We use these models to evaluate targeted therapies, particularly epigenetic and immunotherapeutic, and optimize these therapies so that they can be translated to clinical trials for affected children and young adults. While we have already introduced innovative approaches, such as intracranial CAR T-cell trials, we believe that the fastest way to cure fatal diseases such as DIPG will be to have an intensely collaborative community that focuses on patients first.
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Who We Work With
We believe that the fastest way to cure fatal diseases such as DIPG is to have an intensely collaborative community that focuses on patients first. We collaborate with top researchers around the world to help move science forward, toward effective treatments and cures of aggressive pediatric brain and spinal cord tumors.