Informational Alert

Due to a measles case in the community, please call before coming to Seattle Children’s if you or your child has potential measles symptoms.

High Priority Alert

Masking and Visitation Changes: Due to high rates of respiratory illnesses in our community, we’ve made changes to our masking and visitation guidelines .

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Vitanza Lab

The goal of the Vitanza Lab is to find new treatments that are both safe and curative for high-grade, aggressive pediatric brain and spinal cord tumors, such as diffuse intrinsic pontine glioma (DIPG), diffuse midline glioma H3 K27M-altered (DMG), and atypical teratoid rhabdoid tumor (ATRT). Our central efforts include:

  • Generating new central nervous system (CNS) tumor laboratory models, including treatment-naïve DIPG/DMG models derived from patient biopsies and autopsy-derived models made possible through generous donations from patients and families across the country.
  • Identifying biologic and epigenetic vulnerabilities in DIPG/DMG so that we can advance the best molecularly-targeted drugs to kill tumor cells.
  • Designing and deploying chimeric antigen receptor (CAR) T cells, an immunotherapy that can be delivered directly into the brain for highly-specific targeted tumor killing – such as on our BrainChild clinical trials.

Featured Projects

Support Our Lab

If you would like to donate to the Vitanza Lab, please choose “Other” and type in “Vitanza Lab” when asked where you want your gift to go. Donate today.

Recent Key Publications

Contact the Vitanza Lab

Nicholas A Vitanza, MD

For questions or inquiries,
email: [email protected]

Physical Address

Ben Towne Center for Childhood Cancer and Blood Disorders Research
B. Wayne Hughes Building 09-148
1920 Terry Ave.
Seattle, WA 98101

Seattle Children’s complies with applicable federal and other civil rights laws and does not discriminate, exclude people or treat them differently based on race, color, religion (creed), sex, gender identity or expression, sexual orientation, national origin (ancestry), age, disability, or any other status protected by applicable federal, state or local law. Financial assistance for medically necessary services is based on family income and hospital resources and is provided to children under age 21 whose primary residence is in Washington, Alaska, Montana or Idaho.