Weston Thomas Powell, MD, PhD

Weston Thomas Powell, MD, PhD

Sleep Medicine, Pulmonary

On staff since July 2023

Children's Title: Attending Physician

Academic Title: Acting Assistant Professor

Research Center: Center for Respiratory Biology and Therapeutics

  • Biography

    Dr. Powell received an MD and PhD from the University of California at Davis School of Medicine. He then completed residency and chief residency in Pediatrics at the University of Washington and Seattle Children’s Hospital. He stayed at the University of Washington and Seattle Children’s Hospital for Sleep Medicine and Pediatric Pulmonary Medicine fellowship. He joined the division of Pediatric Pulmonary and Sleep Medicine at the University of Washington and Seattle Children’s Hospital in 2023. After childhoods in California, he and his wife now call the Pacific Northwest home as they raise their children.

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  • Publications

    Manuscripts in Refereed Journals

    • Moore DJ, Powell W, Boyer D, Bline K, Harshman L, Nowalk A, Burns A, Orange JS, NPSCW
      National Pediatrician-Scientist Collaborative Workgroup comment on new ACGME requirements' impact on pediatric physician-scientists.
      37684431 Pediatric research, 2023 Sep 8
    • Powell WT, Reeves SR
      From small to big, using microRNA profiling to investigate infant origins of childhood asthma.
      37536728 The European respiratory journal, 2023 Aug. : 62(2)
    • Powell WT, Rich LM, Vanderwall ER, White MP, Debley JS
      Temperature synchronisation of circadian rhythms in primary human airway epithelial cells from children.
      36198442 BMJ open respiratory research, 2022 Oct. : 9(1) PMCID:PMC9535174
    • Burns AM, Moore DJ, Forster CS, Powell W, Thammasitboon S, Hostetter MK, Weiss P, Boyer D, Ward MA, Blankenburg R, Heyman MB, Rassbach CE, McPhillips H, French A, Nguyen S, Byrne BJ, Parsons DW, Gonzalez F, Nowalk AJ, Ho J, Kumar S, Orange JS, Ackerman KG
      Physician-Scientist Training and Programming in Pediatric Residency Programs: A National Survey.
      34280401 The Journal of pediatrics, 2022 Feb. : 2415-9.e3
    • Christophers B, Gallo Marin B, Oliva R, Powell WT, Savage TJ, Michelow IC
      Trends in clinical presentation of children with COVID-19: a systematic review of individual participant data.
      32942286 Pediatric research, 2022 Feb. : 91(3)494-501 PMCID:PMC7965792
    • Powell WT, Dundon KMW, Frintner MP, Kornfeind K, Haftel HM
      Parenthood, Parental Benefits, and Career Goals Among Pediatric Residents: 2008 and 2019.
      34814184 Pediatrics, 2021 Dec 1 : 148(6)
    • Dundon KM, Powell WT, Wilder JL, King B, Schwartz A, McPhillips H, Best JA, APPD LEARN Parenthood in Pediatric Residency Study Consortium
      Parenthood and Parental Leave Decisions in Pediatric Residency.
      34584002 Pediatrics, 2021 Oct. : 148(4)
    • Forster CS, Nguyen ST, Powell WT, Moore DJ, Ho J, Heyman MB, Wenger TL, Gonzalez F, Hostetter M, Nowalk A, Rassbach CE, Boyer D, Weiss P, Blankenburg RL, Orange JS, Ackerman KG, Burns AM, National Pediatric Physician-Scientist Collaborative Workgroup
      Perspectives from the Society for Pediatric Research: advice on sustaining science and mentoring during COVID-19.
      33469179 Pediatric research, 2021 Oct. : 90(4)738-743 PMCID:PMC7814517
    • DelRosso LM, Chan J, Ruth C, Powell WT, Arp M, Hanevold C, Ferri R
      Ambulatory blood pressure monitoring in children undergoing polysomnography.
      33535275 Journal of sleep research, 2021 Aug. : 30(4)e13280
    • Powell WT, Campbell JA, Ross F, Peña Jiménez P, Rudzinski ER, Dickerson JA
      Acute ANCA Vasculitis and Asymptomatic COVID-19.
      33472989 Pediatrics, 2021 April : 147(4)
    • Powell WT, Chen M, Kraft D, Albers E
      Sleep-disordered breathing in pediatric heart transplant recipients.
      33105526 Pediatric transplantation, 2021 March : 25(2)e13888
    • Powell WT, Schaaf CP, Rech ME, Wrede J
      Polysomnographic characteristics and sleep-disordered breathing in Schaaf-Yang syndrome.
      32889788 Pediatric pulmonology, 2020 Nov. : 55(11)3162-3167
    • Burns AM, Ackerman KG, Thammasitboon S, Rassbach CE, Ward MA, Blankenburg RL, Forster CS, McPhillips HA, Wenger TL, Powell WT, Heyman MB, Hogarty MD, Boyer D, Hostetter M, Weiss P, Nguyen ST, Parsons DW, Moore DJ, Byrne BJ, French AR, Orange JS
      Fixing the leaky pipeline: identifying solutions for improving pediatrician-scientist training during pediatric residency.
      32179872 Pediatric research, 2020 Aug. : 88(2)163-167
    • Coulson RL, Powell WT, Yasui DH, Dileep G, Resnick J, LaSalle JM
      Prader-Willi locus Snord116 RNA processing requires an active endogenous allele and neuron-specific splicing by Rbfox3/NeuN.
      30124848 Human molecular genetics, 2018 Dec 1 : 27(23)4051-4060 PMCID:PMC6240740
    • Powell WT, Borghese RA, Kalanetra KM, Mirmiran M, Mills DA, Underwood MA
      Probiotic Administration in Infants With Gastroschisis: A Pilot Randomized Placebo-Controlled Trial.
      26545203 Journal of pediatric gastroenterology and nutrition, 2016 June : 62(6)852-857 PMCID:PMC4854817
    • Powell WT, LaSalle JM
      Epigenetic mechanisms in diurnal cycles of metabolism and neurodevelopment.
      26105183 Human molecular genetics, 2015 Oct 15 : 24(R1)R1-9 PMCID:PMC4683361
    • Powell WT, Coulson RL, Crary FK, Wong SS, Ach RA, Tsang P, Alice Yamada N, Yasui DH, Lasalle JM
      A Prader-Willi locus lncRNA cloud modulates diurnal genes and energy expenditure.
      23771028 Human molecular genetics, 2013 Nov 1 : 22(21)4318-28 PMCID:PMC3792690
    • Powell WT, Coulson RL, Gonzales ML, Crary FK, Wong SS, Adams S, Ach RA, Tsang P, Yamada NA, Yasui DH, Chédin F, LaSalle JM
      R-loop formation at Snord116 mediates topotecan inhibition of Ube3a-antisense and allele-specific chromatin decondensation.
      23918391 Proceedings of the National Academy of Sciences of the United States of America, 2013 Aug 20 : 110(34)13938-43 PMCID:PMC3752217
    • LaSalle JM, Powell WT, Yasui DH
      Epigenetic layers and players underlying neurodevelopment.
      23731492 Trends in neurosciences, 2013 Aug. : 36(8)460-70 PMCID:PMC3735843
    • Meguro-Horike M, Yasui DH, Powell W, Schroeder DI, Oshimura M, Lasalle JM, Horike S
      Neuron-specific impairment of inter-chromosomal pairing and transcription in a novel model of human 15q-duplication syndrome.
      21725066 Human molecular genetics, 2011 Oct 1 : 20(19)3798-810 PMCID:PMC3168289
    • Christiaen L, Davidson B, Kawashima T, Powell W, Nolla H, Vranizan K, Levine M
      The transcription/migration interface in heart precursors of Ciona intestinalis.
      18535245 Science (New York, N.Y.), 2008 Jun 6 : 320(5881)1349-52

  • Research Funding

    Grant Title Grantor Amount Award Date
    Sleep Research Society Career Development Award
    Parker B. Francis Fellowship
    ATS ASPIRE Fellowship 2023

Overview

Board Certification(s)

Pediatrics
Sleep Medicine

Medical/Professional School

University of California Davis, Davis, CA
University of California-Davis/School of Medicine, Sacramento, CA

Residency

University of Washington Pediatric Residency, Seattle, WA
University of Washington School of Medicine, Seattle, WA

Fellowship

University of Washington School of Medicine, Seattle, WA

Research Description

My long-term goal is to conduct translational research investigating circadian rhythms in pediatric airway and lung diseases. Specifically, I want to understand how circadian rhythm regulation contributes to disease pathobiology to develop novel therapeutic approaches to pediatric airway and lung diseases. Ultimately, the goal is to help answer questions like why do asthma exacerbations most often start at night? Why does cough worsen at night? And, how can we incorporate time of day into how we practice and understand disease?