Rafael E Hernandez, MD, PhD

Rafael E Hernandez, MD, PhD


  • On Staff Since: July 2014
  • Biography

    Rafael E. Hernandez, MD, PhD, is a member of the Center for Global Infectious Disease Research (CGIDR) at Seattle Children's Research Institute and an acting instructor in the Department of Pediatrics, Division of Infectious Diseases, at the University of Washington. He also provides patient care as an attending physician in pediatric infectious diseases at Seattle Children's Hospital.

    He studied biology as an undergraduate at Dartmouth College and then completed a combined MD/PhD program at the University of Washington School of Medicine. He was a pediatrics resident and a fellow in pediatric infectious diseases at Seattle Childrens Hospital. He conducted his fellowship research with Dr. Lalita Ramakrishnan at the University of Washington before joining Seattle Children's Hospital as a principal investigator, focusing on mycobacterial pathogens.

    Board Certification(s)

    Pediatric Infectious Diseases


    University of Washington, Seattle, WA


    University of Washington School of Medicine, Seattle, WA


    Seattle Children's Hospital, Seattle, WA

    Research Description

    The Hernandez Lab research focuses on understanding the pathogenesis of mycobacteria, including tuberculosis and related bacteria. In particular, he seeks to understand how mycobacteria interact with cells of the immune system to promote their own survival and how this interaction makes the bacteria more difficult to treat with antibiotics. Hernandez also heads the Cystic Fibrosis Isolate Core, which provides CF bacterial isolates to researchers at both academic/not-for-profit and commercial research institutions. The core collection contains thousands of isolates from CF patients. Core services to academic researchers are funded by the NIH as part of the Cystic Fibrosis Research and Translation Center at the University of Washington and Seattle Children's Research Institute.

  • Related Resources

    • Hernandez Lab

      In the Hernandez Lab, we use a combination of genetics, molecular biology, cell culture models and animal models to probe the interactions between mycobacterial pathogens and host immune cells.

  • Patient Testimonials

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  • Awards and Honors

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  • Clinical Trials and Research Studies

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