Leslie Ann Dervan, MD

Leslie Ann Dervan, MD

Critical Care, Pediatric Intensive Care Unit (PICU)

On staff since September 2014

Children's Title: Co-Director, Neurocritical Care Program

Academic Title: Assistant Professor

Research Center: Center for Clinical and Translational Research

  • Dr. Leslie Dervan is an attending physician in the Seattle Children’s Hospital Pediatric Intensive Care Unit.  She attended medical school at Harvard Medical School and completed pediatric residency in the Boston Combined Residency Program at Children’s Hospital Boston, followed by pediatric critical care fellowship at Seattle Children’s Hospital and an MS degree in epidemiology at the University of Washington. 

    Dr. Dervan is an Assistant Professor in Pediatrics at the University of Washington, where her research focuses on neurologic conditions in critically ill children and the effects of sedation management, sleep, and ICU delirium on outcomes following critical illness.  This research work supports her areas of clinical expertise including pediatric neurocritical care, critical care pharmacology, sedation management, and optimizing recovery for critically ill children.   

  • Other Publications

    • Dervan LA, Killien EY, Smith MB, Watson RS
      Health-Related Quality of Life Following Delirium in the PICU.
      34534165 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2022 Feb. 1 : 23(2)118-128 PMCID:PMC8816806
    • Sanchez REA, Wrede JE, Watson RS, de la Iglesia HO, Dervan LA
      Actigraphy in mechanically ventilated pediatric ICU patients: comparison to PSG and evaluation of behavioral circadian rhythmicity.
      34634983 Chronobiology international, 2022 Jan. : 39(1)117-128
    • Ista E, Redivo J, Kananur P, Choong K, Colleti J Jr, Needham DM, Awojoodu R, Kudchadkar SR, International PARK-PICU Investigators.
      ABCDEF Bundle Practices for Critically Ill Children: An International Survey of 161 PICUs in 18 Countries.
      34259659 Critical care medicine, 2022 Jan. 1 : 50(1)114-125
    • Killien EY, Rivara FP, Dervan LA, Smith MB, Watson RS
      Components of Health-Related Quality of Life Most Affected Following Pediatric Critical Illness.
      34415865 Critical care medicine, 2022 Jan. 1 : 50(1)e20-e30
    • Fink EL, Robertson CL, Wainwright MS, Roa JD, Lovett ME, Stulce C, Yacoub M, Potera RM, Zivick E, Holloway A, Nagpal A, Wellnitz K, Czech T, Even KM, Brunow de Carvalho W, Rodriguez IS, Schwartz SP, Walker TC, Campos-Miño S, Dervan LA, Geneslaw AS, Sewell TB, Pryce P, Silver WG, Lin JE, Vargas WS, Topjian A, Alcamo AM, McGuire JL, Domínguez Rojas JA, Muñoz JT, Hong SJ, Muller WJ, Doerfler M, Williams CN, Drury K, Bhagat D, Nelson A, Price D, Dapul H, Santos L, Kahoud R, Francoeur C, Appavu B, Guilliams KP, Agner SC, Walson KH, Rasmussen L, Janas A, Ferrazzano P, Farias-Moeller R, Snooks KC, Chang CH, Yun J, Schober ME, Global Consortium Study of Neurologic Dysfunction in COVID-19 (GCS-NeuroCOVID) Investigators.
      Prevalence and Risk Factors of Neurologic Manifestations in Hospitalized Children Diagnosed with Acute SARS-CoV-2 or MIS-C.
      35066369 Pediatric neurology, 2021 Dec. 28 : 12833-44 PMCID:PMC8713420
    • Koth AM, Chan T, Tjoeng YL, Watson RS, Dervan LA
      Delirium in a Tertiary Pediatric Cardiac Intensive Care Unit: Risk Factors and Outcomes.
      34898312 Journal of intensive care medicine, 2021 Dec. 13 : 8850666211066892
    • Carlton EF, Pinto N, Smith M, Fink EL, Watson RS, Hoehn KS, Marupudi N, Dervan LA, Lackey M, Ringwood M, Maddux AB, POST-PICU Investigators of the PALISI Network and the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network.
      Overall Health Following Pediatric Critical Illness: A Scoping Review of Instruments and Methodology.
      34261948 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2021 Dec. 1 : 22(12)1061-1071 PMCID:PMC8639621
    • Chan SW, Dervan LA, Watson RS, Anderson AE, Lai YC
      Epilepsy duration is an independent factor for electrocardiographic changes in pediatric epilepsy.
      34235879 Epilepsia open, 2021 Sept. : 6(3)588-596 PMCID:PMC8408606
    • Cronin MT, Di Gennaro JL, Watson RS, Dervan LA
      Haloperidol and Quetiapine for the Treatment of ICU-Associated Delirium in a Tertiary Pediatric ICU: A Propensity Score-Matched Cohort Study.
      33634425 Paediatric drugs, 2021 March : 23(2)159-169
    • Maddux AB, Pinto N, Fink EL, Hartman ME, Nett S, Biagas K, Killien EY, Dervan LA, Christie LM, Luckett PM, Loftis L, Lackey M, Ringwood M, Smith M, Olson L, Sorenson S, Meert KL, Notterman DA, Pollack MM, Mourani PM, Watson RS, Pediatric Outcomes STudies after PICU (POST-PICU) and PICU-COS Investigators of the Pediatric Acute Lung Injury and Sepsis Investigators and the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Networks.
      Postdischarge Outcome Domains in Pediatric Critical Care and the Instruments Used to Evaluate Them: A Scoping Review.
      33009099 Critical care medicine, 2020 Dec. : 48(12)e1313-e1321 PMCID:PMC7708523
    • Kudchadkar SR, Nelliot A, Awojoodu R, Vaidya D, Traube C, Walker T, Needham DM, Prevalence of Acute Rehabilitation for Kids in the PICU (PARK-PICU) Investigators and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.
      Physical Rehabilitation in Critically Ill Children: A Multicenter Point Prevalence Study in the United States.
      32168030 Critical care medicine, 2020 May : 48(5)634-644 PMCID:PMC7539558
    • Dervan LA, Di Gennaro JL, Farris RWD, Watson RS
      Delirium in a Tertiary PICU: Risk Factors and Outcomes.
      31568239 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2020 Jan. : 21(1)21-32
    • Dervan LA, Watson RS
      The Fragility of Using p Value Less Than 0.05 As the Dichotomous Arbiter of Truth.
      31162357 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2019 June : 20(6)582-583
    • Killien EY, Farris RWD, Watson RS, Dervan LA, Zimmerman JJ
      Health-Related Quality of Life Among Survivors of Pediatric Sepsis.
      30720672 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2019 June : 20(6)501-509 PMCID:PMC6548660
    • Dervan LA, Zimmerman JJ, Thompson AE, Watson RS
      In Conclusion, Word Choice Matters: Female Physician Leadership and Cardiopulmonary Resuscitation Outcomes.
      30882449 Critical care medicine, 2019 April : 47(4)e383
    • Nellis ME, Goel R, Karam O, Cushing MM, Davis PJ, Steiner ME, Tucci M, Stanworth SJ, Spinella PC, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network, Pediatric Critical Care Blood Research Network (BloodNet), and the P3T Investigators., P3T Investigators.
      Effects of ABO Matching of Platelet Transfusions in Critically Ill Children.
      30422914 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2019 Feb. : 20(2)e61-e69 PMCID:PMC6709973
    • Nellis ME, Karam O, Mauer E, Cushing MM, Davis PJ, Steiner ME, Tucci M, Stanworth SJ, Spinella PC, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) network, Pediatric Critical Care Blood Research Network (BloodNet), and the P3T Investigators.
      Platelet Transfusion Practices in Critically Ill Children.
      29727368 Critical care medicine, 2018 Aug. : 46(8)1309-1317 PMCID:PMC6476545
    • Watson RS, Choong K, Colville G, Crow S, Dervan LA, Hopkins RO, Knoester H, Pollack MM, Rennick J, Curley MAQ
      Life after Critical Illness in Children-Toward an Understanding of Pediatric Post-intensive Care Syndrome.
      29728304 The Journal of pediatrics, 2018 July : 19816-24
    • Watson RS, Asaro LA, Hertzog JH, Sorce LR, Kachmar AG, Dervan LA, Angus DC, Wypij D, Curley MAQ, RESTORE Study Investigators and the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.
      Long-Term Outcomes after Protocolized Sedation versus Usual Care in Ventilated Pediatric Patients.
      29313710 American journal of respiratory and critical care medicine, 2018 June 1 : 197(11)1457-1467 PMCID:PMC6005554
    • Traube C, Silver G, Reeder RW, Doyle H, Hegel E, Wolfe HA, Schneller C, Chung MG, Dervan LA, DiGennaro JL, Buttram SD, Kudchadkar SR, Madden K, Hartman ME, deAlmeida ML, Walson K, Ista E, Baarslag MA, Salonia R, Beca J, Long D, Kawai Y, Cheifetz IM, Gelvez J, Truemper EJ, Smith RL, Peters ME, O'Meara AM, Murphy S, Bokhary A, Greenwald BM, Bell MJ
      Delirium in Critically Ill Children: An International Point Prevalence Study.
      28079605 Critical care medicine, 2017 April : 45(4)584-590 PMCID:PMC5350030
    • Dervan LA, Yaghmai B, Watson RS, Wolf FM
      The use of methadone to facilitate opioid weaning in pediatric critical care patients: a systematic review of the literature and meta-analysis.
      28109052 Paediatric anaesthesia, 2017 March : 27(3)228-239
    • Dervan LA, King MA, Cuschieri J, Rivara FP, Weiss NS
      Pediatric solid organ injury operative interventions and outcomes at Harborview Medical Center, before and after introduction of a solid organ injury pathway for pediatrics.
      26218688 The journal of trauma and acute care surgery, 2015 Aug. : 79(2)215-20 PMCID:PMC4716013
    • Dervan LA, Watson RS
      Incorporating Morbidity Into PICU Quality Measures: A "TOPICC" of Critical Importance.
      26181120 Critical care medicine, 2015 Aug. : 43(8)1781-2
    • Sullivan PM, Dervan LA, Reiger S, Buddhe S, Schwartz SM
      Risk of congenital heart defects in the offspring of smoking mothers: a population-based study.
      25578997 The Journal of pediatrics, 2015 April : 166(4)978-984.e2
    • Dervan L, Poliakov A, Friedman SD, Shaw D, Pihoker C, Roberts JS, Richards T, Marro K, Vavilala MS
      Change in fractional anisotropy during treatment of diabetic ketoacidosis in children.
      24105411 Pediatric research, 2014 Jan. : 75(1-1)62-6

Overview

Board Certification(s)

Pediatrics
Pediatric Critical Care Medicine

Medical/Professional School

University of Washington, Seattle, WA
Harvard Medical School, Boston, MA

Residency

Boston Children's Hospital, Boston, MA

Fellowship

Seattle Children's Hospital, Seattle, WA