Helen L Dichek, MD

Endocrinology and Diabetes, Lipid Disorders Program, Congenital Adrenal Hyperplasia Program

On staff since February 2001

Academic Title: Associate Professor, Endocrinology

Research Center: Center for Clinical and Translational Research

Patient Testimonials
- Jong-Won Bothell, WA 01.07.22
  
  We always love to see Dr. Helen Dichek and purposely choose to see her even though there is a closer location. I have a child with special needs and we have known Dr. Dichek since 2012. She is the best doctor that we have experience with, who is not only concerned about my son's hyperthyroidism but also his growth in other aspects of his life. She truly sees a person and not just a patient. The annual doctor visits with her became a huge time of healing for a family like us. Moreover, my first daughter was greatly inspired to join the medical field through her encounters with Dr. Dichek. At present, she is attending the UW School of Nursing.
Recommend Helen L Dichek, MD

Awards and Honors

Award Name	Award Description	Awarded By	Award Date
SEATTLE TOP DOCTOR - 2022		Seattle Magazine	2022

Publications
Other Publications
- Flynn R, Qian K, Tang C, Dronadula N, Buckler JM, Jiang B, Wen S, Dichek HL, Dichek DA
  Expression of apolipoprotein A-I in rabbit carotid endothelium protects against atherosclerosis.
  21772254 Molecular therapy : the journal of the American Society of Gene Therapy, 2011 Oct. : 19(10)1833-41 PMCID:PMC3188740
- Farris SD, Hu JH, Krishnan R, Emery I, Chu T, Du L, Kremen M, Dichek HL, Gold E, Ramsey SA, Dichek DA
  Mechanisms of urokinase plasminogen activator (uPA)-mediated atherosclerosis: role of the uPA receptor and S100A8/A9 proteins.
  21536666 The Journal of biological chemistry, 2011 Jun 24 : 286(25)22665-77 PMCID:PMC3121410
- Chiu HK, Qian K, Ogimoto K, Morton GJ, Wisse BE, Agrawal N, McDonald TO, Schwartz MW, Dichek HL
  Mice lacking hepatic lipase are lean and protected against diet-induced obesity and hepatic steatosis.
  20056822 Endocrinology, 2010 March : 993-1001
- Krishnan R, Kremen M, Hu JH, Emery I, Farris SD, Slezicki KI, Chu T, Du L, Dichek HL, Dichek DA
  Level of macrophage uPA expression is an important determinant of atherosclerotic lesion growth in Apoe-/- mice.
  19729604 Arteriosclerosis, thrombosis, and vascular biology, 2009 Nov. : 1737-44
- Frutkin AD, Otsuka G, Stempien-Otero A, Sesti C, Du L, Jaffe M, Dichek HL, Pennington CJ, Edwards DR, Nieves-Cintrón M, Minter D, Preusch M, Hu JH, Marie JC, Dichek DA
  TGF-[beta]1 limits plaque growth, stabilizes plaque structure, and prevents aortic dilation in apolipoprotein E-null mice.
  19325140 Arteriosclerosis, thrombosis, and vascular biology, 2009 Sept. : 1251-7
- Taleban S, Carew HT, Dichek HL, Deeb SS, Hollenback D, Weigle DS, Cummings DE, Brunzell JD
  Energy balance in congenital generalized lipodystrophy type I.
  18640396 Metabolism: clinical and experimental, 2008 Aug. : 1155-61
- Eacker SM, Agrawal N, Qian K, Dichek HL, Gong EY, Lee K, Braun RE
  Hormonal regulation of testicular steroid and cholesterol homeostasis.
  18032697 Molecular endocrinology (Baltimore, Md.), 2008 March : 623-35
- Qian K, Agrawal N, Dichek HL
  Reduced atherosclerosis in chow-fed mice expressing high levels of a catalytically inactive human hepatic lipase.
  17234195 Atherosclerosis, 2007 Nov. : 66-74
- Dichek HL, Agrawal N, El Andaloussi N, Qian K
  Attenuated corticosterone response to chronic ACTH stimulation in hepatic lipase-deficient mice: evidence for a role for hepatic lipase in adrenal physiology.
  16368783 American journal of physiology. Endocrinology and metabolism, 2006 May : E908-15
- Dichek HL, Qian K, Agrawal N
  Divergent effects of the catalytic and bridging functions of hepatic lipase on atherosclerosis.
  15205216 Arteriosclerosis, thrombosis, and vascular biology, 2004 Sept. : 1696-702
- Cozen AE, Moriwaki H, Kremen M, DeYoung MB, Dichek HL, Slezicki KI, Young SG, Véniant M, Dichek DA
  Macrophage-targeted overexpression of urokinase causes accelerated atherosclerosis, coronary artery occlusions, and premature death.
  15096455 Circulation, 2004 May 4 : 2129-35
- Dichek HL, Qian K, Agrawal N
  The bridging function of hepatic lipase clears plasma cholesterol in LDL receptor-deficient "apoB-48-only" and "apoB-100-only" mice.
  14679168 Journal of lipid research, 2004 March : 551-60
- Ishida T, Zheng Z, Dichek HL, Wang H, Moreno I, Yang E, Kundu RK, Talbi S, Hirata K, Leung LL, Quertermous T
  Molecular cloning of nonsecreted endothelial cell-derived lipase isoforms.
  14667806 Genomics, 2004 Jan. : 24-33