Senior Director, Therapeutics Cell Manufacturing Facility/Quality Assurance
Catherine Lindgren is responsible for directing the manufacturing and quality control operations of the facility and ensuring that compliance to strict quality assurance parameters are met. She has more than 35 years of laboratory research experience moving promising new discoveries from the research bench into human clinical cancer research trials, and over 20 years of experience in GMP quality assurance, overseeing the manufacturing and release of therapeutics for cell-based clinical trials. She came to the facility after overseeing similar facilities at the University of Washington and Fred Hutchinson Cancer Center. She holds a BS from Washington State University and a certification in biomedical regulatory affairs from the University of Washington.
Director, GMP Cell Production
Chris Brown leads the facility's manufacturing/process development team and played a key role in its development and startup and that of its cleanroom facility. He has more than 20 years of experience in the manufacturing of cellular products for phase 1 and 2 clinical trials. He joined Seattle Children's Research Institute from Fred Hutchinson Cancer Center, where he oversaw a team responsible for performing clinical production in a cleanroom facility. He holds a BA from Carleton College.
Director, Research Quality Control
Stephanie Mgebroff oversees the facility's quality control program, ensuring that therapeutic cell products are safe and meet pre-established specifications prior to being released to the clinical team. Upon joining Seattle Children’s Research Institute, she played a key role in development of the facility's core infrastructure and standard procedures, including quality control policy development and implementation. Mgebroff has over 15 years of cell therapy and protocol development experience. Prior to joining Seattle Children’s in 2011, she worked at both the Fred Hutchinson Cancer Center's cellular processing facility and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins School of Medicine. She holds an MS from Johns Hopkins University.