Multimodal Treatment of Desmoplastic Small Round Cell Tumors: Factors Influencing Survival: A Pediatric Surgical Oncology Research Collaborative Study
DSRCT PSORC Study
What is the goal of the study?
Desmoplastic small round cell tumor (DSRCT) is a rare soft tissue sarcoma that is often asymptomatic until advanced stages and is associated with high mortality rates. Treatment regimens are multimodal, and each treatment modality carries significant potential morbidity. Given these risks, the survival benefits of a complete treatment regimen treatment must be weighed against the associated morbidity. This study has two primary aims. The first aim of this study will be to retrospectively evaluate the relative contributions of different treatment modalities on survival (5-yr abdominal EFS and OS) and to assess the relative impact of each modality on treatment-related morbidity. The second aim of this study will be to prospectively assess quality of life by (1) examining how the associated morbidity of these treatment components impact survivors’ quality of life through validated measures (2) exploring how parents and patients perceive treatment decisions.
Who can participate in the study?
Please contact the study team listed below to learn more.