Profile

Janet A. Englund, MD

Janet A. Englund, MD

Infectious Disease, Infectious Disease Research

On staff since November 2002

Academic Title: Professor

Research Center: Center for Clinical and Translational Research

"I've always been interested in preventing disease. Finding ways to keep children healthy is what I love to do. I began focusing on vaccines because they are one of the best ways to stop children and adults from getting sick in the first place. By working to make vaccines safe and effective, I feel like I'm making a difference in the lives of many people around the world."

  • Biography

    Janet A. Englund, MD: Professor of Pediatric Infectious Diseases. My research interests include the study of vaccine-preventable diseases and viral respiratory diseases in young children and immunocompromised hosts, including transplant recipients, as well as the evaluation of antiviral therapy for the prevention and treatment of viral diseases.

    As a Clinical Associate at Fred Hutchinson Cancer Research Center, I am active in many transplant-related protocols in the prevention and treatment of disease in the immunocompromised host. As a member of the NIH-sponsored Seattle Vaccine Treatment and Evaluation Unit, I am involved in research with new vaccines and maternal immunization with Tdap and influenza vaccines. I am also involved in the evaluation of new respiratory virus vaccines including live-attenuated parainfluenza virus vaccines through collaboration with Johns Hopkins University and the NIH. My research group is actively studying the epidemiology of respiratory viruses and viral vaccines in diverse populations, including infants, children,and pregnant women.

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  • Awards and Honors

    Award Name Award Description Awarded By Award Date
    SEATTLE'S TOP DOCTOR - 2016 Seattle Magazine 2016
    Seattles Top Doctor 2016 Seattle Met Magazine 2016
    Distinguished Pediatric Infectious Disease Physician PID Society 2015
    SEATTLE'S TOP DOCTOR - 2015 Seattle Met Magazine 2015
    SEATTLE'S TOP DOCTOR - 2014 Seattle Metropolitan Magazine 2014
    Seattle's Top Doc Seattle Met Magazine 2013

  • Publications

    • Hughes MM, Katz J, Englund JA, Khatry SK, Shrestha L, Leclerq SC, Steinhoff M, Tielsch JM
      Infant vaccination timing: Beyond traditional coverage metrics for maximizing impact of vaccine programs, an example from southern Nepal
      226788880 Vaccine , 2016 : 37(7)933-41
    • Chu H, Chin J, , Pollard J, Englund JA
      Outpatient and inpatient respiratory syncytial virus infections in immunocompromised children
      Influenza Other Resp Viruses , 2016 : Epub ahead of print
    • Qin X, Zerr DM, Kronman MP, Adler AL, Berry JE, Rich S, Buccat AM, Xu M, Englund JA
      Comparison of Molecular Detection Methods for Pertussis in Children during a State-wide Outbreak
      27121506 Ann Clin Micro Antimicrob , 2016 : 1528-35 PMCID: 4847268
    • Waghmare A, Englund JA, Boeckh M
      How I treat respiratory viral infections in the setting of intensive chemotherapy or hematopoietic cell transplantation
      26968533 Blood , 2016
    • Carpenter P, Englund JA.
      How I vaccinate blood and bone marrow transplant recipients
      27048212 Blood , 2016
    • Chu HY, Katz J, Tielsch J, Khatry AK, Shrestha L, Leclerq SC, Magaret A, Kuypers J, Steinhoff M, Englund JA
      Clinical presentation and birth outcomes associated with RSV infection in pregnancy
      26859306 PlosOne , 2016
    • Seo S, Campbell AP, Gooley T, Kuypers J, Stednick Z, Jerome KR, Englund JA, Boeckh M
      Human metapneumovirus infections following hematopoietic cell transplantation: Factors associated with disease progression
      27143659 Clin Inf Dis , 2016
    • . Hughes MM, Katz J, Englund JA, Khatry SK, Shrestha L, Leclerq SC, Steinhoff M, Tielsch JM
      . Infant vaccination timing: Beyond traditional coverage metrics for maximizing impact of vaccine programs, an example from southern Nepal.
      26788880 Vaccine , 2016 : 34(7)933-41
    • Tielsch JM, Steinhoff M, Katz J, Englund JA, Kuypers J, Khatry SK, Shrestha L, LeClerq SC
      Designs of two randomized, community-based trials to assess the impact of influenza immunization during pregnancy on respiratory illness among pregnant women and their infants and reproductive outcomes in rural Nepal.
      25783721 BMC pregnancy and childbirth , 2015 Dec. : 15(1)470 PMCID: PMC4339255
    • Karron RA, Buchholz U, Loehr K, Luongo C, Bhagvanji T, Englund JA, Collins P
      A gene deletion that up-regulates viral gene expression yields an attenuated RSV vaccine with improved antibody responses in children
      26537255 Sci Transl Med , 2015 Nov. 4 : 7(312)
    • Payne DC, Tate JC, Azimi P, Boom JA, Englund JA, Staat MA, Halasa N, Weinberg G, Szilagyi P, Chappell J, McNeal M, Klein E, Sahni L, Harrison CJ, Baker C, Bernstein D, Moffatt M, Selvarangan R
      Long-term Consistency in Rotavirus Vaccine Protection: RV5 and RV1 Vaccine Effectiveness in US Children
      26449565 Clin Infect Dis , 2015 Oct. 8
    • Campbell AJ, Guthrie KA, Englund JA, Farney RM, Minerich EL, Kuypers J, Corey L, Boeckh M
      Clinical Outcomes Associated with Respiratory Virus Detection before Allogeneic Hematopoietic Stem Cell Transplantation
      25847977 Clin Infect Dis , 2015 July 15 : 61(2)192-202
    • Tarlock K, Johnson D, Cornell C, Parnell S, Meshinchi S, Baker KS, Englund JA
      Elevated fluoride levels and periostitis in pediatric hematopoietic stem cell transplant recipients receiving long-term voriconazole.
      25327935 Pediatric blood and cancer , 2015 May : 62(5)918-20
    • Strelitz B, Gritton J, Klein EJ, Bradford MC, Follmer K, Zerr DM, Englund JA, Opel DJ
      Parental vaccine hesitancy and acceptance of seasonal influenza vaccine in the pediatric emergency department.
      25744225 Vaccine , 2015 Mar. 2
    • Waghmare A, Pergam SA, Jerome KR, Englund JA, Boeckh M, Kuypers J
      Clinical disease due to enterovirus D68 infection in adult hematologic malignancy patients and hematopoietic cell transplant recipients
      25593338 Blood , 2015 : 125(11)1724-9 PMCID: 4357580
    • Currier RL, Payne DL, Staat MA, Selvarangan R, Halasa N, Boom J, Englund JA, Szilagyi P, Wikswo M, Shirley SH, Parashar U, Vinje J, Morrow AL
      Innate susceptibility to norovirus infections influenced by FUT2 genotype in a United States pediatric population
      25744498 Clinical Infectious Disease , 2015 : In Press
    • Martin ET, Kuypers J, McRoberts JP, Englund JA, Zerr, DM
      Human bocavirus-1 primary infection and shedding in infants
      25632039 Journal of Infectious Disease , 2015 : Online
    • Martin EK, Kuypers J, Chu HY, Lacombe K, Qin X, Strelitz B, Bradford M, Jones C, Klein EJ, Englund JA
      Molecular Epidemiology of human rhinovirus infections in the pediatric emergency department
      25542466 Journal of Clinical Virology , 2015 : 6225-31
    • Kimberlin DW, Jester PM, Snchez PJ, Ahmed A, Arav-Boger R, Michaels M, Ashouri N, Englund JA, Estrada B, Jacobs RF, Romero JR, Sood SK, Whitworth MS, Abzug MJ, Caserta MT, Fowler S, Lujan-Zilbermann J, Storch GA, DeBiasi RL, Han J-Y, Palmer A, Weiner LB, Bocchini JA, Dennehy PH, Finn A, Griffiths P, Gutierrez K, Halasa N, Homans J, Shane A, Sharland M, Simonsen K, Vanchiere JA, Woods CR, Sabo DL, Aban I, Kuo H, James SH, Prichard MN, Griffin J, Giles G, Acosta EP, Whitley RJ, for the NIAID Collaborative Antiviral Study Group (CASG).
      Valganciclovir for Symptomatic Congenital Cytomegalovirus Disease
      25738669 New England Journal of Medicine , 2015 : 372(10)933-43
    • Campbell AJ, Guthrie KA, Englund JA, Farney RM, Minerich EL, Kuypers J, Corey L, Boeckh M
      Clinical Outcomes Associated with Respiratory Virus Detection before Allogeneic Hematopoietic Stem Cell Transplantation
      Clin Infect Dis , 2015
    • Chu HY, Huang D, Scott E, Chan JD, Jain R, Pottinger P, Lynch JB, Dellit TH, Jerome K, Englund JA, Kuypers J
      Impact of rapid influenza PCR testing on hospitalization and antiviral use: A retrospective cohort study
      26017150 J Med Virol , 2015 : 87(12)2021-6
    • Payne DC, Currier RL, Staat MA, Sahni LC, Selvanrangan R, Halasa N, Azimi PH, Englund JA, Weinberg G, Boom JA, Szilagyi PG, Klein EJ, Johnston SH, Chappell J, Harrison CJ, Davidson BS, Mijatovic-Rustempasic SM, Wikswo M, Bowen MD, Morrow AD, Parashar UD
      Epidemiologic association between FUT2 secretor status and severe rotavirus gastroenteritis in US children
      26389824 JAMA Pediatrics , 2015 : 149(11)1040-5
    • Currier RL, Payne DL, Staat MA, Selvarangan R, Halasa N, Boom J, Englund JA, Szilagyi P, Wikswo M, Shirley SH, Parashar U, Vinje J, Morrow AL
      Inate Susceptibility to Norovirus Infections Influenced by FTU2 Genotype in a United States Pediatric Population
      25744498 Clin Infect Dis , 2015 : 60(11)1631-8
    • Payne DC, Tate JC, Azimi P, Boom JA, Englund JA, Staat MA, Halasa N, Weinberg G, Szilagyi P, Chappell J, McNeal M, Klein E, Sahni L, Harrison CJ, Baker C, Bernstein D, Moffatt M, Selvarangan R
      Long-term Consistency in Rotavirus Vaccine Protection: RV5 and RV1 Vaccine Effectiveness in US Children
      26449565 Clin Infect Dis , 2015
    • Martin EK, Kuypers J, Chu HY, Lacombe K, Qin X, Strelitz B, Bradford M, Jones C, Klein EJ, Englund JA
      Molecular Epidemiology of human rhinovirus infections in the pediatric emergency department
      25542466 J Clin Virology , 2015 : 6225-31
    • Cheng G-S, Campbell AP, Xie H, Stednick Z, Leisenring W, Englund JA, Chien JW, Boeckh M
      Correlation and agreement of handheld spirometry with laboratory spirometry in allogeneic hematopoietic cell transplant recipients
      Biol Blood Marrow Transplant , 2015 : Epub ahead of print
    • Burroughs LM, Nemecek ER, Torgerson TR, Storer BE, Talano JA, Domm J, Giller RH, Shimamura A, Delaney C, Skoda-Smith S, Thakar MS, Baker KS, Rawlings DJ, Englund JA, Flowers ME, Deeg HJ, Storb R, Woolfrey AE
      Treosulfan-based conditioning and hematopoietic cell transplantation for nonmalignant diseases: a prospective multicenter trial.
      25196857 Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation , 2014 Dec. : 20(12)1996-2003 PMCID: PMC4324724
    • Chu HY, Steinhoff MC, Magaret A, Zaman K, Roy E, Langdon G, Formica MA, Walsh EE, Englund JA
      Respiratory syncytial virus transplacental antibody transfer and kinetics in mother-infant pairs in Bangladesh.
      24903663 The Journal of infectious diseases , 2014 Nov. 15 : 210(10)1582-9 PMCID: PMC4334795
    • Kotloff KL, Halasa NB, Harrison CJ, Englund JA, Walter EB, King JC, Creech CB, Healy SA, Dolor RJ, Stephens I, Edwards KM, Noah DL, Hill H, Wolff M
      Clinical and immune responses to inactivated influenza A(H1N1)pdm09 vaccine in children.
      25222307 The Pediatric infectious disease journal , 2014 Aug. : 33(8)865-71 PMCID: PMC4166548
    • Javid PJ, Sanchez SE, Jacob S, McNeal MM, Horslen SP, Englund JA
      The Safety and Immunogenicity of Rotavirus Vaccination in Infants With Intestinal Failure.
      24567844 Journal of the Pediatric Infectious Diseases Society , 2014 Mar. : 3(1)57-65 PMCID: PMC3933047
    • Carter J, Lenahan J, Ishak G, Geyer R, Pollard J, Englund JA
      Successful medical management of invasive fungal infections of the central nervous system in immunocompromised children
      25407593 Pediatric Blood Cancer , 2014 : 18
    • Callahan ST, Wolff M, Hill HR, Edwards KM, VTEU Pandemic H1N1 Vaccine Study Group
      Impact of Body Mass Index on Immunogenicity of pendemic H1N1 vaccine in children and adutls
      Journal of Infectious Disease , 2014 : 201(8)24795475
    • Keller-Stanislawski B, Englund JA, Kang G, Mangtani P, Neuzil K, Nohynek H, Pless R, Warton M, Lambach P, Zuber P
      Safety of immunization during pregnancy: A review of the evidence, Global Advisory committee on Vaccine Safety
      25285883 Vaccine , 2014 : 32(52)7057-64
    • Chu HY, Englund JA, Sterlitz B, Lacombe K, Jones C, Follmer K, Martin EK, Bradford M, Zin X, Kuypers J, Klein E
      Rhinovirus disease in children seeking care in the emergency department
      Journal of Pediatric Infectious Disease , 2014 : 3286-93
    • Panpradist N, Toley BJ, Zhang X, Byrnes S, Buser JR, Englund JA, Lutz BR
      Swab sample transfer for point-of-care diagnostics: characterization of swab types and manual agitation methods
      25181250 PLoS One , 2014 : 9(9)
    • Kronman MP, Zerr DM, Qin X, Englund JA, Cornell C, Sanders JE, Myers J, Rayar J, Berry JE, Adler AL, Weissman SJ
      Intestinal decontamination of multidrug-resistant Klebsiella pneumoniae after recurrent infections in an immunocompromised host
      25041704 Diangnostic Microbiology and Infectious Disease , 2014 : 8087-89
    • Seo S, Xie H, Karron RA, Thumar B, Englund JA, Leisenring WM, Boeckh M, Campbell AP
      Parainfluenza virus type 3 antibody in allogeneic hematopoietic cell transplant recipients: Factors influencing post-transplantation antibody titers and associated outcomes
      24978141 Bone Marrow Transplant , 2014 : 491205-11
    • Chu HY, Englund JA
      Maternal Immunization
      24799324 Clincal Infectious Disease , 2014 : 59560-8
    • Waghmare A, Wagner T, Andrews R, Smith S, Kuypers J, Moss R, Englund JA
      Successful treatment of parainfluenza virus respiratory tract infection with DAS181 in four immunocompromised children
      Journal of Pediatric Infectious Disease , 2014
    • Munoz FM, Bond NH, Maccatto M, Pinell P, Hammill H, Swamy GK, Walter E, Jackson LA, Englund JA, Edwards MS, Healy CM, Petrie C, Ferreira J, Goll J, Baker CJ
      Safety and immunogenicity of tetanus diphtheria and acellular pertussis (Tdap) immunization during pregnancy in mothers and infants: A randomized clinical trial
      24794369 JAMA , 2014 : 3111760-9
    • Chu HY, Englund JA, Podczervinski S, Kuypers J, Campbell AP, Boeckh M, Pergam SA, Casper C
      Nosocomial transmission of respiratory syncytial virus in an outpatient cancer center
      24607551 Biol Blood Marrow Transplant , 2014 : 20844-51
    • Seo S, Hu Xie, Campbell AP, Kuypers JM, Leisenring WM, Englund JA, Boeckh M
      Parainfluenza virus lower respiratory tract disease after hematopoietic cell transplantation: Viral detection in the lung predicts outcome
      24599766 Clinical Infectious Disease , 2014 : 581357-68
    • Kim YJ, Guthrie KA, Waghmare A, Walsh E, Falsey A, Kuypers J, Cent A, Englund JA, Boeckh M
      Respiratory syncytial virus in hematopoietic transplant recipients: Factors determining progression from upper to lower respiratory tract disease
      24368837 Journal of Infectious Dsiease , 2014 : 20091195-1204
    • Chu HY, Renaud C, Ficken E, Thomson B, Kuypers J, Englund JA
      Respiratory tract infections due to human metapneumovirus in immunocompromised children
      25419459 J Ped Inf Dis Soc , 2014 : 3286-93
    • Englund JA and Moscona A
      Parainfluenza Viruses (Chapter)
      Viral Infections of Humans , 2014 : 5th Edition
    • Englund JA and Moscona A
      Parainfluenza Viruses (Chapter)
      Viral Infections of Humans , 2014 : 5th Edition
    • Atmar R, Englund JA
      Rhinoviruses (Chapter)
      Feigin and Cherry Textbook of Pediatric Infectious Diseases , 2014 : Third Edition
    • McIntosh K, Englund JA
      Coronaviruses (Chapter)
      Feigin and Cherry Textbook of Pediatric Infectious Diseases, Third Edition , 2014 : Third Edition
    • Chu HY, Steinhoff M, Magaret A, Zaman K, Roy E, Langdon G, Formica MA, Walsh EE, Englund JA
      Respiratory syncytial virus transplacental antibody transfer and kinetics in mother-infant pairs in Bangladesh
      24903663 J Infect Dis , 2014 : 201(10)560-8 PMCID: 4334795
    • Englund JA, Karron RA, Cunningham CK, Larussa P, Melvin A, Yogev R, Handelsman E, Siberry GK, Thumar B, Schappell E, Bull CV, Chu HY, Schaap-Nutt A, Buchholz U, Collins PL, Schmidt AC, International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) P1096 Study Group
      Safety and infectivity of two doses of live-attenuated recombinant cold-passaged human parainfluenza type 3 virus vaccine rHPIV3cp45 in HPIV3-seronegative young children.
      24103895 Vaccine , 2013 Nov. 19 : 31(48)5706-12
    • Chu HY, Kuypers J, Renaud C, Wald A, Martin E, Fairchok M, Magaret A, Sarancino M, Englund JA
      Molecular epidemiology of respiratory syncytial virus transmission in childcare.
      23684816 Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology , 2013 Aug. : 57(4)343-50 PMCID: PMC3800193
    • Renaud C, Xie H, Seo S, Kuypers J, Cent A, Corey L, Leisenring W, Boeckh M, Englund JA
      Mortality rates of human metapneumovirus and respiratory syncytial virus lower respiratory tract infections in hematopoietic cell transplantation recipients.
      23680472 Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation , 2013 Aug. : 19(8)1220-6 PMCID: PMC3752411
    • Seo S, Campbell AP, Xie H, Chien JW, Leisenring WM, Englund JA, Boeckh M
      Outcome of respiratory syncytial virus lower respiratory tract disease in hematopoietic cell transplant recipients receiving aerosolized ribavirin: significance of stem cell source and oxygen requirement.
      23298855 Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation , 2013 Apr, : 19(4)589-96 PMCID: PMC3667608
    • Martin ET, Fairchok MP, Stednick ZJ, Kuypers J, Englund JA
      Epidemiology of multiple respiratory viruses in childcare attendees.
      23288925 The Journal of infectious diseases , 2013 Mar. 15 : 207(6)982-9
    • Kimberlin DW, Acosta EP, Prichard MN, Sánchez PJ, Ampofo K, Lang D, Ashouri N, Vanchiere JA, Abzug MJ, Abughali N, Caserta MT, Englund JA, Sood SK, Spigarelli MG, Bradley JS, Lew J, Michaels MG, Wan W, Cloud G, Jester P, Lakeman FD, Whitley RJ, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group
      Oseltamivir pharmacokinetics, dosing, and resistance among children aged andlt;2 years with influenza.
      23230059 The Journal of infectious diseases , 2013 Mar. 1 : 207(5)709-20 PMCID: PMC3563309
    • Renaud C, Kuypers J, Xie H, Cent A, Corey L, Boeckh M, Englund JA
      Human metapneumovirus and respiratory syncytial virus lower respiratory tract infections in hematopoietic stem cell transplant recipients have high mortality rates.
      BBMT , 2013 : 191220-6
    • Campbell AP, Kuypers J, Englund JA, Guthrie KA, Corey L, Boeckh M
      Self-collection of foam nasal swabs for respiratory virus detection by PCR among immunocompetent subjects and hematopoietic cell transplant recipients.
      23135933 Journal of clinical microbiology , 2013 Jan. : 51(1)324-7 PMCID: PMC3536199
    • Seo S, Englund JA, Nguyen JT, Pukrittayakamee S, Lindegardh N, Tarning J, Tambyah PA, Renaud C, Went GT, de Jong MD, Boeckh MJ
      Combination therapy with amantadine, oseltamivir and ribavirin for influenza A infection: safety and pharmacokinetics.
      23264438 Antiviral therapy , 2013 : 18(3)377-86
    • Xu M, Qin X, Astion ML, Rutledge JC, Simpson J, Jerome KR, Englund JA, Zerr DM, Migita RT, Rich S, Childs JC, Cent A, Del Beccaro MA
      Implementation of filmarray respiratory viral panel in a core laboratory improves testing turnaround time and patient care.
      23270907 American journal of clinical pathology , 2013 Jan. : 139(1)118-23
    • Chu HY, Englund JA
      Respiratory syncytial virus disease: prevention and treatment.
      24362693 Current topics in microbiology and immunology , 2013 : 372235-58
    • Danziger-Isakov L, Allen U, Englund J, Herold B, Hoffman J, Green M, Gantt S, Kumar D, Michaels MG
      Recommended curriculum for training in pediatric transplant infectious diseases
      J Pediatr Infect Dis Soc , 2013
    • Lafond KE, Englund JA, Tam JS, Bresee JS
      Overview of influenza vaccines in the pediatric population
      J Ped Inf Dis Soc , 2013
    • Seo S, Martin E, Xie H, Kuypers JM, Campbell AP, Choi SM, Waghmare A, Leisenring, Jerome K, Englund JA, Boeckh MJ
      Human rhinovirus RNA detection in the lower respiratory tract of hematopoietic cell transplant recipients: Association with Mortality
      BBMT , 2013 : 19S167-8
    • Choi SM, Xie H, Campbell AP, Kuypers J, Leisenring W, Boudreault AA, Englund JA, Corey L, Boeckh M
      Influenza viral RNA detection in blood as a marker to predict disease severity in hematopoietic cell transplant recipients.
      23033148 The Journal of infectious diseases , 2012 Dec. 15 : 206(12)1872-7 PMCID: PMC3502377
    • Kuypers J, Campbell AP, Guthrie KA, Wright NL, Englund JA, Corey L, Boeckh M
      WU and KI polyomaviruses in respiratory samples from allogeneic hematopoietic cell transplant recipients.
      23017213 Emerging infectious diseases , 2012 Oct. : 18(10)1580-8 PMCID: PMC3471632
    • Englund J
      A conversation with Janet Englund, MD. Interview by Stanford T. Shulman.
      22765042 Pediatric annals , 2012 July : 41(7)296
    • Burns JL, Emerson J, Kuypers J, Campbell AP, Gibson RL, McNamara S, Worrell K, Englund JA
      Respiratory viruses in children with cystic fibrosis: viral detection and clinical findings.
      21955319 Influenza and other respiratory viruses , 2012 May : 6(3)218-23
    • Society for Healthcare Epidemiology of America, Infectious Diseases Society of America, Pediatric Infectious Diseases Society
      Policy statement on antimicrobial stewardship by the Society for Healthcare Epidemiology of America (SHEA), the Infectious Diseases Society of America (IDSA), and the Pediatric Infectious Diseases Society (PIDS).
      22418625 Infection control and hospital epidemiology , 2012 Apr, : 33(4)322-7
    • Lundgren IS, Englund JA, Burroughs LM, Torgerson TR, Skoda-Smith S
      Outcomes and duration of Pneumocystis jiroveci pneumonia therapy in infants with severe combined immunodeficiency.
      21817949 The Pediatric infectious disease journal , 2012 Jan. : 31(1)95-7 PMCID: PMC3244569
    • Martin ET, Kuypers J, Wald A, Englund JA
      Multiple versus single virus respiratory infections: viral load and clinical disease severity in hospitalized children.
      21668660 Influenza and other respiratory viruses , 2012 Jan. : 6(1)71-7 PMCID: PMC3175338
    • Renaud C, Englund JA
      Antiviral therapy of respiratory viruses in haematopoietic stem cell transplant recipients.
      22311587 Antiviral therapy , 2012 : 17(1 Pt B)175-91
    • Kim YJ, M Boeckh, Cook L, Stempel H, Jerome KR, Boucek Jr R, Burroughs L, Englund JA
      Cytomegalovirus infection and ganciclovir resistance due to UL97 mutations in pediatric transplant recipients
      23198963 Transplant Infect Dis , 2012 : 14611-7
    • Braun LE, Renaud C, Fairchok MP, Kuypers J, Englund JA, Martin ET
      Human parechovirus and other enteric viruses in childcare attendees in the era of rotavirus vaccines
      J Pediatr Infect Dis Soc , 2012 : 1136-43
    • Englund JA, Burns J
      Infectious Complications in Special Hosts" (Chapter 108)
      Pediatric Infectious Diseases , 2012 : Fourth Edition
    • Renaud C, Kuypers J, Englund JA
      Emerging oseltamivir resistance in seasonal and pandemic influenza A/H1N1.
      21684202 Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology , 2011 Oct. : 52(2)70-8
    • Fairchok MP, Martin ET, Kuypers J, Englund JA
      A prospective study of parainfluenza virus type 4 infections in children attending daycare.
      21317680 The Pediatric infectious disease journal , 2011 Aug. : 30(8)714-6
    • Renaud C, Kuypers J, Aspesberro F, Rosenfeld M, Englund JA
      Emergence of oseltamivir-resistant pandemic H1N1 in an immunocompetent child with severe status asthmaticus.
      21604924 The Journal of asthma : official journal of the Association for the Care of Asthma , 2011 Aug. : 572-5
    • Boudreault AA, Xie H, Leisenring W, Englund J, Corey L, Boeckh M
      Impact of corticosteroid treatment and antiviral therapy on clinical outcomes in hematopoietic cell transplant patients infected with influenza virus.
      20870025 Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation , 2011 July : 17(7)979-86 PMCID: PMC3676866
    • Ortiz JR, Englund JA, Neuzil KM
      Influenza vaccine for pregnant women in resource-constrained countries: a review of the evidence to inform policy decisions.
      21550377 Vaccine , 2011 June 15 : 29(27)4439-52
    • Halasa N, Englund JA, Nachman S, Weinberg GA, Huber VC, Allison K, Dubovsky F, Yi T, McCullers JA, Flynn PM
      Safety of live attenuated influenza vaccine in mild to moderately immunocompromised children with cancer.
      21496468 Vaccine , 2011 May 31 : 29(24)4110-5
    • Choi SM, Boudreault AA, Xie H, Englund JA, Corey L, Boeckh M
      Differences in clinical outcomes after 2009 influenza A/H1N1 and seasonal influenza among hematopoietic cell transplant recipients.
      21372154 Blood , 2011 May 12 : 117(19)5050-6 PMCID: PMC3109531
    • Renaud C, Kuypers J, Ficken E, Cent A, Corey L, Englund JA
      Introduction of a novel parechovirus RT-PCR clinical test in a regional medical center.
      21397555 Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology , 2011 May : 51(1)50-3
    • Kay M, Zerr DM, Englund JA, Cadwell BL, Kuypers J, Swenson P, Kwan-Gett TS, Bell SL, Duchin JS
      Shedding of pandemic (H1N1) 2009 virus among health care personnel, Seattle, Washington, USA.
      21470453 Emerging infectious diseases , 2011 Apr, : 17(4)639-44 PMCID: PMC3377395
    • Renaud C, Boudreault AA, Kuypers J, Lofy KH, Corey L, Boeckh MJ, Englund JA
      H275Y mutant pandemic (H1N1) 2009 virus in immunocompromised patients.
      21470455 Emerging infectious diseases , 2011 Apr, : 17(4)653-60; quiz 765 PMCID: PMC3290123
    • National Center for Immunization and Respiratory Diseases
      General recommendations on immunization --- recommendations of the Advisory Committee on Immunization Practices (ACIP).
      21293327 MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports / Centers for Disease Control , 2011 Jan. 28 : 60(2)1-64
    • Englund J, Feuchtinger T, Ljungman P
      Viral infections in immunocompromised patients.
      21195305 Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation , 2011 Jan. : 17(1 Suppl)S2-5 PMCID: PMC3030455
    • Feltes TF, Sondehimer HM, Tulloh RM, Harris BS, Jensen KM, Losonsky GA, Griffin MP, Motavizumab Cardiac Study Group
      A randomized controlled trial of motavizumab versus palivizumab for the prophylaxis of serious respiratory syncytial virus disease in children with hemodynamically significant congenital heart disease
      21522037 Ped Res , 2011 : 70186-91
    • Boeckh M, Englund JA
      Evaluation of therapeutics for RSV: an important step forward.
      21079265 American journal of respiratory and critical care medicine , 2010 Nov. 15 : 182(10)1217-9
    • Taylor JA, Weber WJ, Martin ET, McCarty RL, Englund JA
      Development of a symptom score for clinical studies to identify children with a documented viral upper respiratory tract infection.
      20520584 Pediatric research , 2010 Sept. : 252-7
    • Fairchok MP, Martin ET, Chambers S, Kuypers J, Behrens M, Braun LE, Englund JA
      Epidemiology of viral respiratory tract infections in a prospective cohort of infants and toddlers attending daycare.
      20650679 Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology , 2010 Sept. : 16-20
    • Singleton RJ, Bulkow LR, Miernyk K, DeByle C, Pruitt L, Hummel KB, Bruden D, Englund JA, Anderson LJ, Lucher L, Holman RC, Hennessy TW
      Viral respiratory infections in hospitalized and community control children in Alaska.
      20513097 Journal of medical virology , 2010 July : 82(7)1282-90
    • Walter EB, Rajagopal S, Zhu Y, Neuzil KM, Fairchok MP, Englund JA
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      7659483 Pediatrics , 1995 : 96(3)592-94
    • Steinhoff MC, Reed GF, Decker MD, Edwards KM, Englund JA, Pichichero ME, Rennels MB, Anderson EL, Deloria MA, Meade BD
      A randomized comparison of reactogenicity and immunogenicity of two whole-cell pertussis vaccines
      7659477 Pediatrics , 1995 : 96(3)567-70
    • Rennels MB, Reed GF, Decker MD, Edwards KM, Pichichero ME, Deloria MA, Englund JA, Anderson EL, Steinhoff MC, Deforest A, et al
      Simultaneous administration of Haemophilus influenzae type b vaccine with acellular or whole-cell pertussis vaccine: effects on reactogenicity and immune responses to pertussis vaccines
      7659479 Pediatrics , 1995 : 96(3)576-79
    • Pichichero ME, Christy C, Decker MD, Steinhoff MC, Edwards KM, Rennels MB, Anderson EL, Englund JA
      Defining the key parameters for comparing reactions among acellular and whole-cell pertussis vaccines
      7659482 Pediatrics , 1995 : 96(3)588-92
    • Whimbey E, Couch RB, Englund JA, Andreeff M, Goodrich JM, Raad II, Lewis V, Mirza N, Luna MA, Baxter B, et al
      Respiratory syncytial virus pneumonia in hospitalized adult patients with leukemia
      8562747 Clin Infect Dis , 1995 : 21(2)376-79
    • Rowen JI, Englund JA
      Brucellosis presenting with cough
      8532438 Pediatr Infect Dis J , 1995 : 14(8)721-22
    • Englund JA, Decker MD, Edwards KM, Pichichero ME, Steinhoff MC, Anderson EL
      Acellular and whole-cell pertussis vaccines as booster doses: a multicenter study
      8265321 Pediatrics , 1994 : 93(1)37-43
    • Vallejo JG, Englund JA, Garcia-Prats JA, Demmler GJ
      Ganciclovir treatment of steroid-associated cytomegalovirus disease in a congenitally infected neonate
      8177639 Pediatr Infect Dis J , 1994 : 13(3)239-41
    • Englund JA, Piedra PA, Ahn YM, Gilbert BE, Hiatt P
      High-dose, short-duration ribavirin aerosol therapy compared with standard ribavirin therapy in children with suspected respiratory syncytial virus infection
      7931890 J Pediatr , 1994 : 125(4)635-41
    • Woods CR, Englund JA
      Congenital toxoplasmosis presenting with eosinophilic meningitis
      8483631 Pediatr Infect Dis J , 1993 : 12(4)347-48
    • Englund JA, Mbawuike IN, Hammill H, Holleman MC, Baxter BD, Glezen WP
      Maternal immunization with influenza or tetanus toxoid vaccine for passive antibody protection in young infants
      8354906 J Infect Dis , 1993 : 168(3)647-56
    • Atmar RL, Englund JA, Hammill H
      Complications of measles during pregnancy
      1571434 Clin Infect Dis , 1992 : 14(1)217-26
    • Glezen WP, Englund JA, Siber GR, Six HR, Turner C, Shriver D, Hinkley CM, Falcao O
      Maternal immunization with the capsular polysaccharide vaccine for Haemophilus influenzae type b
      1588147 J Infect Dis , 1992 : 165(Suppl 1)S134-S136
    • Peltier MK, Filipovich AH, Bechtel M, Dirksen CL, Englund JA
      Randomized double-blinded comparison of three intravenous immunoglobulin products in bone marrow transplantation
      1324529 Semin Hematol , 1992 : 29(3 Suppl 2)112-15
    • Englund JA, Glezen WP, Barreto L
      Controlled study of a new five-component acellular pertussis vaccine in adults and young children
      1431261 J Infect Dis , 1992 : 166(6)1436-41
    • Filipovich AH, Peltier MH, Bechtel MK, Dirksen CL, Strauss SA, Englund JA
      Circulating cytomegalovirus (CMV) neutralizing activity in bone marrow transplant recipients: comparison of passive immunity in a randomized study of four intravenous IgG products administered to CMV-seronegative patients
      1330079 Blood , 1992 : 80(10)2656-60
    • Englund JA, Anderson LJ, Rhame FS
      Nosocomial transmission of respiratory syncytial virus in immunocompromised adults
      1993745 J Clin Microbiol , 1991 : 29(1)115-19 PMCID: 269714
    • Englund JA, Fletcher CV, Balfour HH Jr
      Acyclovir therapy in neonates
      2066845 J Pediatr , 1991 : 119(1)129-35
    • Fletcher CV, Englund JA, Edelman CK, Gross CR, Dunn DL, Balfour HH Jr
      Pharmacologic basis for high-dose oral acyclovir prophylaxis of cytomegalovirus disease in renal allograft recipients
      1649575 Antimicrob Agents Chemother , 1991 : 35(5)938-43 PMCID: 245132
    • Englund JA, Zimmerman ME, Swierkosz EM, Goodman JL, Scholl DR, Balfour HH Jr
      Herpes simplex virus resistant to acyclovir. A study in a tertiary care center
      2155570 Ann Intern Med , 1990 : 112(6)416-22
    • Balfour HH Jr, Kelly JM, Suarez CS, Heussner RC, Englund JA, Crane DD, McGuirt PV, Clemmer AF, Aeppli DM
      Acyclovir treatment of varicella in otherwise healthy children
      2156984 J Pediatr , 1990 : 116(4)633-39
    • Engel JP, Englund JA, Fletcher CV, Hill EL
      Treatment of resistant herpes simplex virus with continuous-infusion acyclovir
      2308204 JAMA , 1990 : 263(12)1662-64
    • Englund JA, Piedra PA, Jefferson LS, Wilson SZ, Taber LH, Gilbert BE
      High-dose, short-duration ribavirin aerosol therapy in children with suspected respiratory syncytial virus infection
      2380833 J Pediatr , 1990 : 117(2 Pt 1)313-20 PMCID: -
    • Englund JA, Arvin AM, Balfour HH Jr
      Acyclovir treatment for varicella does not lower gpI and IE-62 (p170) antibody responses to varicella-zoster virus in normal children
      2172288 J Clin Microbiol , 1990 : 28(10)2327-30 PMCID: 268170
    • Englund JA, Suarez CS, Kelly J, Tate DY, Balfour HH Jr
      Placebo-controlled trial of varicella vaccine given with or after measles-mumps-rubella vaccine
      2535873 J Pediatr , 1989 : 114(1)37-44
    • Fletcher CV, Englund JA, Bean B, Chinnock B, Brundage DM, Balfour HH Jr
      Continuous infusion of high-dose acyclovir for serious herpesvirus infections
      2552909 Antimicrob Agents Chemother , 1989 : 33(8)1375-78
    • Sia EO, Englund JA, Sannerud K, Hansen K, Shah N, Balfour HH Jr
      Recovery of human immunodeficiency virus type 1 from supernatant fluid of routine viral cultures
      2768453 J Clin Microbiol , 1989 : 27(7)1664-66
    • Hertz MI, Englund JA, Snover D, Bitterman PB, McGlave PB
      Respiratory syncytial virus-induced acute lung injury in adult patients with bone marrow transplants: a clinical approach and review of the literature
      2677595 Medicine (Baltimore) , 1989 : 68(5)269-81
    • Chutze GE, Englund JA, Bresee JS
      Pseudomonas aeruginosa endogenous endophthalmitis in a neonate
      25166223 Pediatr Infect Dis J , 1989 : 8(12)893-95
    • Jackson JB, Erice A, Englund JA, Edson JR, Balfour HH Jr
      Prevalence of cytomegalovirus antibody in hemophiliacs and homosexuals infected with human immunodeficiency virus type 1
      2895517 Transfusion , 1988 : 28(2)187-89
    • Englund JA, Sullivan CJ, Jordan MC, Dehner LP, Vercellotti GM, Balfour HH Jr
      Respiratory syncytial virus infection in immunocompromised adults
      3389604 Ann Intern Med , 1988 : 109(3)203-08
    • Sharp HL, Lindahl JA, Freese DK, Burke B, Englund J, Johnson D, Johnson SB, Holman RT
      A new hepato-pancreato-renal disorder resembling tyrosinemia involving neuropathy and abnormal metabolism of polyunsaturated acids
      2832582 J Pediatr Gastroenterol Nutr , 1988 : 7(2)167-76
    • Erice A, Hertz MI, Snyder LS, Englund J, Edelman CK, Balfour HH Jr
      Evaluation of centrifugation cultures of bronchoalveolar lavage fluid for the diagnosis of cytomegalovirus pneumonitis
      2854035 Diagn Microbiol Infect Dis , 1988 : 10(4)205-12
    • Englund JA, Fletcher CV, Johnson D, Chinnock B, Balfour HH Jr
      Effect of blood exchange on acyclovir clearance in an infant with neonatal herpes
      3794878 J Pediatr , 1987 : 110(1)151-53
    • Bean B, Fletcher C, Englund J, Lehrman SN, Ellis MN
      Progressive mucocutaneous herpes simplex infection due to acyclovir-resistant virus in an immunocompromised patient: correlation of viral susceptibilities and plasma levels with response to therapy
      2820649 Diagn Microbiol Infect Dis , 1987 : 7(3)199-204
    • Englund JA, Breningstall GN, Heck LJ, Lazuick JS, Karabatsos N, Calisher CH, Tsai TF
      Diagnosis of western equine encephalitis in an infant by brain biopsy
      3725645 Pediatr Infect Dis , 1986 : 5(3)382-84
    • Englund JA, Lucas RV Jr
      Cardiac complications in children with systemic lupus erythematosus. Pediatrics
      6634279 Pediatrics , 1983 : 72(5)724-30
    • Wiltrakis SM, Cloud GA, Whitley RJ, Sanchez PJ, Ampofo K, Lang D, Ashouri N, Vacnchiere JA, Abzug MJ, Abughali N, Casrta MT, Englund JA, Sood SK, Spigarelli MG, Bradley JS, Lew J, Michaels MG, Jester PM, Kimberlin DW
      Presenting symptoms and predictors of disease severity in infants with influenza: Results of a national collaborative trial
      Submitted for Publication
    • Chin J, Englund JA, Pollard J, Chu H.
      Outpatient and inpatient respiratory syncytial virus infections in immunocompromised children
      Submitted for Publication
    • Chu HY, Huang D, Scott E, Chan JD, Jain R, Pottinger P, Lynch JB, Dellit TH, Jerome K, Englund JA, Kuypers J
      Impact of rapid influenza PCR testing on hospitalization and antiviral use: A retrospective cohort study
      Submitted for Publication
    • Englund JA, Madhi S
      Whooping Cough in Adults: Getting the Right Diagnosis

      http://www.medscape.org/viewarticle/839615
    • Englund, JA
      Pertussis Prevention Strategies in Women: Protecting the Newborn

      http://www.medscape.org/viewarticle/839138

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  • Presentations

    Presentations Title Event Location Date
    Rationale for Maternal Immunization Global Maternal newborn health Conference mexico City, Mexico Oct. 19, 2015
    Antiviral Advances That Will Change Your Practice Infectious Diseases Society of America Annual Meeting San Diego, CA Oct. 8, 2015
    Maternal Immunization: I 15th Advanced Vaccinology course co-sponsored by Fondation Merieux/NIH/WHO/CDC Annecy, France May 14, 2015 - May 16, 2015
    Influenza Vaccine: The Good, the Bad, and the Controversial Don Katterman Memorial Lecture Univ. of Washington School of Pharmacy May 7, 2015
    RSV endpoints for clinical trials WHO meeting Geneva, Switzerland March 22, 2015 - March 24, 2015
    Monitoring vaccine safety and Impact of Maternal Vaccines Bill and Melinda Gates Symposium on Maternal Vaccination Berlin, Germany Jan. 28, 2015
    Panelist: Monitoring vaccine safety and Impact of Maternal Vaccines Bill and Melinda Gates Symposium on Maternal Vaccination Berlin, Germany Jan. 28, 2015
    Maternal Immunization for RSV: Issues and Potential RSV Vaccine Forum Oxford, England Jan. 22, 2015
    Maternal Immunization for RSV: Issues and Potential RSV Vaccine Forum Oxford University, Oxford, England Jan. 22, 2015
    Update of Respiratory Viruses in Immunocompromised Children St. Jude Research Hospital, Memphis, TN Dec. 17, 2014
    John Adams Memorial Lecture: Respiratory Syncytial Virus Childrens Hospital of Los Angeles Los Angeles, CA Oct. 16, 2014
    Maternal Immunization: I 14th Advanced Vaccinology course co-sponsored by Fondation Merieux/NIH/WHO/CDC Annecy, France May 21, 2014 - May 22, 2014
    Clinical Vaccine Trials Washington Biotechnology and Biomedical Association Seattle, WA April 30, 2014
    Panelist, "Maternal Immunization," Global vaccine and Immunization Research Forum Gates Foundation, WHO, NIH March 3, 2014 - March 6, 2014
    "Respiratory Viruses Pre- and Post-Transplant " and "Clinical Disease and Treatment of Adeno and BK virus During Transplant" St. Judes-PIDS First Annual Pediatric Transplant Conference Memphis, TN Feb. 20, 2014 - Feb. 12, 2014
    Prevention Strategies for Pertussis: Maternal immunization and Cocooning World Society for Pediatric Infectious Diseases Cape Town, South Africa Nov. 19, 2013
    New Respiratory Viruses Dept. of Virology and Infectious Disease University of Cape Town, South Africa Nov. 18, 2013
    Respiratory Viral Disease in Children Resident lecture, Samsung Hospital Seoul, South Korea Nov. 9, 2013
    Update in Respiratory Viruses Korean Society of Pediatric Inf. Disease Seoul, South Korea Nov. 8, 2013
    "New Respiratory Viral Vaccines" and "Maternal and Fetal Immunization" Korean Society of Infectious Diseases Seoul, South Korea Nov. 7, 2013
    "Maternal immunization for RSV" RSV Vaccines for the World Porto, Portugal Oct. 14, 2013
    Vaccines for special populations INDVAC (Indian Vaccinology Course) 2013 Vellore, India Sept. 18, 2013 - Sept. 21, 2013
    "Respiratory Viruses Epidemiology", "Influenza Vaccines", "Vaccines for Special Populations" INDVAC 2013 Vellore, India Sept. 18, 2013 - Sept. 21, 2013
    Maternal Vaccination against Viral Diseases Global Expert Meeting (GEMS) Vienna, Austria Sept. 16, 2013
    New Questions about Pediatric Vaccines Virginia Mason Pediatrics Seattle, WA Aug. 28, 2013
    New Respiratory Syncytial Virus Vaccines Maternal Immunization Conference Antalya, Turkey March 14, 2013
    Respiratory virus infections in the immunocompromised host; Argentina Pediatric Infectious Disease Society Bueno Aires, Argentina March 13, 2013

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  • Research Funding

    Grant Title Grantor Amount Award Date
    Clinical Significance of rhinovirus Seattle Children's Hospital Clinical Translational Research Center Dec. 20, 2012 - Sept. 30, 2013
    RSV surveillance and antibody levels in Southeast Asia PATH May 2012 - June 2014
    New Vaccine Surveillance Network CDC Aug. 1, 2011 - July 31, 2015
    Operation of a Facility for the Study of Infectious Agents, Vaccines, and Antimicrobials NIH/ Subsite of Johns Hopkins April 7, 2009 - April 6, 2013
    Maternal Immunization to protect the Mother and Neonate Bill and Melinda Gates Fndn Jan. 2009 - Dec. 2014

Overview

Board Certification(s)

Pediatrics
Pediatric Infectious Diseases

Medical/Professional School

University of Michigan Medical School, Ann Arbor

Residency

Pediatrics, Fairview University Medical Center, Minneapolis

Fellowship

Infectious Disease, University of Minnesota , Minneapolis
Infectious Disease, University of Minnesota , Minneapolis

Research Description

My research interests include the study of vaccine-preventable diseases and viral respiratory diseases in young children and immunocompromised hosts, including transplant recipients, as well as the evaluation of antiviral therapy for the prevention and treatment of viral diseases.

As a Clinical Associate of Fred Hutchinson Cancer Research Center, I am active in many transplant-related protocols in the prevention and treatment of disease in the immunocompromised host. As a member of the NIH-sponsored Seattle Vaccine Treatment and Evaluation Unit, I am involved in research with new vaccines and maternal immunization with Tdap and influenza vaccines.

My research group is active in studying influenza virus vaccines in diverse populations, including infants, school-age children in the schools, and pregnant women.

Research Focus Area

Immunocompromised Hosts, Virology, Infectious Disease