Ron L Gibson, MD, PhD

Manuscripts in Refereed Journals

• Mayer-Hamblett N, Rosenfeld M, Gibson RL, Ramsey BW, Kulasekara HD, Retsch-Bogart GZ, Morgan W, Wolter DJ, Pope CE, Houston LS, Kulasekara BR, Khan U, Burns JL, Miller SI, Hoffman LR
  Pseudomonas aeruginosa in vitro Phenotypes Distinguish Cystic Fibrosis Infection Stages and Outcomes.
  24937177 American journal of respiratory and critical care medicine, 2014 June

Published Abstracts

• Ron Gibson, MD, PhD
  Abstracts - Available upon request
  

Other Publications

• Zemanick ET, Emerson J, Thompson V, McNamara S, Morgan W, Gibson RL, Rosenfeld M, EPIC Study Group
  Clinical outcomes after initial pseudomonas acquisition in cystic fibrosis.
  24644274 Pediatric pulmonology, 2015 Jan. : 50(1)42-8
• Brown PS, Pope CE, Marsh RL, Qin X, McNamara S, Gibson R, Burns JL, Deutsch G, Hoffman LR
  Directly sampling the lung of a young child with cystic fibrosis reveals diverse microbiota.
  25072206 Annals of the American Thoracic Society, 2014 Sept. : 11(7)1049-55 PMCID:PMC4214062
• Emerson J, Cochrane E, McNamara S, Kuypers J, Gibson RL, Campbell AP
  Home Self-Collection of Nasal Swabs for Diagnosis of Acute Respiratory Virus Infections in Children With Cystic Fibrosis.
  24363931 Journal of the Pediatric Infectious Diseases Society, 2013 Dec. : 2(4)345-351 PMCID:PMC3869469
• Mayer-Hamblett N, Rosenfeld M, Treggiari MM, Konstan MW, Retsch-Bogart G, Morgan W, Wagener J, Gibson RL, Khan U, Emerson J, Thompson V, Elkin EP, Ramsey BW, EPIC, ESCF Investigators
  Standard care versus protocol based therapy for new onset Pseudomonas aeruginosa in cystic fibrosis.
  23818295 Pediatric pulmonology, 2013 Oct. : 48(10)943-53
• Mayer-Hamblett N, Rosenfeld M, Treggiari MM, Konstan MW, Retsch-Bogart G, Morgan W, Wagener J, Gibson RL, Khan U, Emerson J, Thompson V, Elkin EP, Ramsey BW, EPIC, ESCF Investigators
  Standard care versus protocol based therapy for new onset Pseudomonas aeruginosa in cystic fibrosis.
  23818295 Pediatric pulmonology, 2013 Oct. : 48(10)943-53
• Guo DC, Regalado E, Casteel DE, Santos-Cortez RL, Gong L, Kim JJ, Dyack S, Horne SG, Chang G, Jondeau G, Boileau C, Coselli JS, Li Z, Leal SM, Shendure J, Rieder MJ, Bamshad MJ, Nickerson DA, GenTAC Registry Consortium, National Heart, Lung, and Blood Institute Grand Opportunity Exome Sequencing Project, Kim C, Milewicz DM
  Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections.
  23910461 American journal of human genetics, 2013 Aug. 8 : 93(2)398-404 PMCID:PMC3738837
• Wolter DJ, Emerson JC, McNamara S, Buccat AM, Qin X, Cochrane E, Houston LS, Rogers GB, Marsh P, Prehar K, Pope CE, Blackledge M, Déziel E, Bruce KD, Ramsey BW, Gibson RL, Burns JL, Hoffman LR
  Staphylococcus aureus small-colony variants are independently associated with worse lung disease in children with cystic fibrosis.
  23625938 Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2013 Aug. : 57(3)384-91
• Fu W, O'Connor TD, Jun G, Kang HM, Abecasis G, Leal SM, Gabriel S, Rieder MJ, Altshuler D, Shendure J, Nickerson DA, Bamshad MJ, NHLBI Exome Sequencing Project, Akey JM
  Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants.
  23201682 Nature, 2013 Jan. 10 : 493(7431)216-20 PMCID:PMC3676746
• O'Connor TD, Kiezun A, Bamshad M, Rich SS, Smith JD, Turner E, NHLBIGO Exome Sequencing Project, ESP Population Genetics, Statistical Analysis Working Group, Leal SM, Akey JM
  Fine-scale patterns of population stratification confound rare variant association tests.
  23861739 PloS one, 2013 : 8(7)e65834 PMCID:PMC3701690
• Rosenfeld M, Bernardo-Ocampo C, Emerson J, Genatossio A, Burns J, Gibson R
  Prevalence of cystic fibrosis pathogens in the oropharynx of healthy children and implications for cystic fibrosis care.
  22551927 Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2012 Sept. : 11(5)456-7
• Rosenfeld M, Emerson J, McNamara S, Thompson V, Ramsey BW, Morgan W, Gibson RL, EPIC Study Group
  Risk factors for age at initial Pseudomonas acquisition in the cystic fibrosis epic observational cohort.
  22554417 Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2012 Sept. : 11(5)446-53
• Emond MJ, Louie T, Emerson J, Zhao W, Mathias RA, Knowles MR, Wright FA, Rieder MJ, Tabor HK, Nickerson DA, Barnes KC, National Heart, Lung, and Blood Institute (NHLBI) GO Exome Sequencing Project, Lung GO, Gibson RL, Bamshad MJ
  Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis.
  22772370 Nature genetics, 2012 July 8 : 44(8)886-9 PMCID:PMC3702264
• Quon BS, Patrick DL, Edwards TC, Aitken ML, Gibson RL, Genatossio A, McNamara S, Goss CH
  Feasibility of using pedometers to measure daily step counts in cystic fibrosis and an assessment of its responsiveness to changes in health state.
  22226414 Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2012 May : 11(3)216-22
• Mayer-Hamblett N, Kronmal RA, Gibson RL, Rosenfeld M, Retsch-Bogart G, Treggiari MM, Burns JL, Khan U, Ramsey BW, EPIC Investigators
  Initial Pseudomonas aeruginosa treatment failure is associated with exacerbations in cystic fibrosis.
  21830317 Pediatric pulmonology, 2012 Feb. : 47(2)125-34 PMCID:PMC3214247
• Mayer-Hamblett N, Kronmal RA, Gibson RL, Rosenfeld M, Retsch-Bogart G, Treggiari MM, Burns JL, Khan U, Ramsey BW, EPIC Investigators
  Initial Pseudomonas aeruginosa treatment failure is associated with exacerbations in cystic fibrosis.
  21830317 Pediatric pulmonology, 2012 Feb. : 47(2)125-34 PMCID:PMC3214247
• Oermann CM, McCoy KS, Retsch-Bogart GZ, Gibson RL, McKevitt M, Montgomery AB
  Pseudomonas aeruginosa antibiotic susceptibility during long-term use of aztreonam for inhalation solution (AZLI).
  21784781 The Journal of antimicrobial chemotherapy, 2011 Oct. : 66(10)2398-404
• Treggiari MM, Retsch-Bogart G, Mayer-Hamblett N, Khan U, Kulich M, Kronmal R, Williams J, Hiatt P, Gibson RL, Spencer T, Orenstein D, Chatfield BA, Froh DK, Burns JL, Rosenfeld M, Ramsey BW, Early Pseudomonas Infection Control (EPIC) Investigators
  Comparative efficacy and safety of 4 randomized regimens to treat early Pseudomonas aeruginosa infection in children with cystic fibrosis.
  21893650 Archives of pediatrics & adolescent medicine, 2011 Sept. : 165(9)847-56
• Wainwright CE, Quittner AL, Geller DE, Nakamura C, Wooldridge JL, Gibson RL, Lewis S, Montgomery AB
  Aztreonam for inhalation solution (AZLI) in patients with cystic fibrosis, mild lung impairment, and P. aeruginosa.
  21441078 Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2011 July : 10(4)234-42
• Moskowitz SM, Emerson JC, McNamara S, Shell RD, Orenstein DM, Rosenbluth D, Katz MF, Ahrens R, Hornick D, Joseph PM, Gibson RL, Aitken ML, Benton WW, Burns JL
  Randomized trial of biofilm testing to select antibiotics for cystic fibrosis airway infection.
  20963843 Pediatric pulmonology, 2011 Feb. : 46(2)184-92 PMCID:PMC3479399
• Oermann CM, Retsch-Bogart GZ, Quittner AL, Gibson RL, McCoy KS, Montgomery AB, Cooper PJ
  An 18-month study of the safety and efficacy of repeated courses of inhaled aztreonam lysine in cystic fibrosis.
  20672296 Pediatric pulmonology, 2010 Nov. : 45(11)1121-34 PMCID:PMC3867945
• Rosenfeld M, Emerson J, McNamara S, Joubran K, Retsch-Bogart G, Graff GR, Gutierrez HH, Kanga JF, Lahiri T, Noyes B, Ramsey B, Ren CL, Schechter M, Morgan W, Gibson RL, EPIC Study Group Participating Clinical Sites
  Baseline characteristics and factors associated with nutritional and pulmonary status at enrollment in the cystic fibrosis EPIC observational cohort.
  20597081 Pediatric pulmonology, 2010 Sept. : 45(9)934-44
• Sanders DB, Hoffman LR, Emerson J, Gibson RL, Rosenfeld M, Redding GJ, Goss CH
  Return of FEV1 after pulmonary exacerbation in children with cystic fibrosis.
  20054859 Pediatric pulmonology, 2010 Feb. : 45(2)127-34
• Bartlett JR, Friedman KJ, Ling SC, Pace RG, Bell SC, Bourke B, Castaldo G, Castellani C, Cipolli M, Colombo C, Colombo JL, Debray D, Fernandez A, Lacaille F, Macek M Jr, Rowland M, Salvatore F, Taylor CJ, Wainwright C, Wilschanski M, Zemková D, Hannah WB, Phillips MJ, Corey M, Zielenski J, Dorfman R, Wang Y, Zou F, Silverman LM, Drumm ML, Wright FA, Lange EM, Durie PR, Knowles MR, Gene Modifier Study Group
  Genetic modifiers of liver disease in cystic fibrosis.
  19738092 JAMA : the journal of the American Medical Association, 2009 Sept. 9 : 302(10)1076-83 PMCID:PMC3711243
• Treggiari MM, Rosenfeld M, Mayer-Hamblett N, Retsch-Bogart G, Gibson RL, Williams J, Emerson J, Kronmal RA, Ramsey BW, EPIC Study Group
  Early anti-pseudomonal acquisition in young patients with cystic fibrosis: rationale and design of the EPIC clinical trial and observational study'.
  19470318 Contemporary clinical trials, 2009 May : 30(3)256-68 PMCID:PMC2783320
• Retsch-Bogart GZ, Quittner AL, Gibson RL, Oermann CM, McCoy KS, Montgomery AB, Cooper PJ
  Efficacy and safety of inhaled aztreonam lysine for airway pseudomonas in cystic fibrosis.
  19420195 Chest, 2009 May : 135(5)1223-32 PMCID:PMC2818415
• Sagel SD, Gibson RL, Emerson J, McNamara S, Burns JL, Wagener JS, Ramsey BW, Inhaled Tobramycin in Young Children Study Group, Cystic Fibrosis Foundation Therapeutics Development Network
  Impact of Pseudomonas and Staphylococcus infection on inflammation and clinical status in young children with cystic fibrosis.
  18822427 The Journal of pediatrics, 2009 Feb. : 154(2)183-8 PMCID:PMC2654617
• Moskowitz SM, Chmiel JF, Sternen DL, Cheng E, Gibson RL, Marshall SG, Cutting GR
  Clinical practice and genetic counseling for cystic fibrosis and CFTR-related disorders.
  19092437 Genetics in medicine : official journal of the American College of Medical Genetics, 2008 Dec. : 10(12)851-68 PMCID:PMC2810953
• McCoy KS, Quittner AL, Oermann CM, Gibson RL, Retsch-Bogart GZ, Montgomery AB
  Inhaled aztreonam lysine for chronic airway Pseudomonas aeruginosa in cystic fibrosis.
  18658109 American journal of respiratory and critical care medicine, 2008 Nov. 1 : 178(9)921-8 PMCID:PMC2577727
• Retsch-Bogart GZ, Burns JL, Otto KL, Liou TG, McCoy K, Oermann C, Gibson RL, AZLI Phase II Study Group
  A phase 2 study of aztreonam lysine for inhalation to treat patients with cystic fibrosis and Pseudomonas aeruginosa infection.
  18041081 Pediatric pulmonology, 2008 Jan. : 43(1)47-58
• Treggiari MM, Rosenfeld M, Retsch-Bogart G, Gibson R, Ramsey B
  Approach to eradication of initial Pseudomonas aeruginosa infection in children with cystic fibrosis.
  17647287 Pediatric pulmonology, 2007 Sept. : 42(9)751-6
• Treggiari MM, Rosenfeld M, Retsch-Bogart G, Gibson R, Ramsey B
  Approach to eradication of initial Pseudomonas aeruginosa infection in children with cystic fibrosis.
  17647287 Pediatric pulmonology, 2007 Sept. : 751-6
• Clancy JP, Rowe SM, Bebok Z, Aitken ML, Gibson R, Zeitlin P, Berclaz P, Moss R, Knowles MR, Oster RA, Mayer-Hamblett N, Ramsey B
  No detectable improvements in cystic fibrosis transmembrane conductance regulator by nasal aminoglycosides in patients with cystic fibrosis with stop mutations.
  17347447 American journal of respiratory cell and molecular biology, 2007 July : 37(1)57-66 PMCID:PMC1899350
• Clancy JP, Rowe SM, Bebok Z, Aitken ML, Gibson R, Zeitlin P, Berclaz P, Moss R, Knowles MR, Oster RA, Mayer-Hamblett N, Ramsey B
  No detectable improvements in cystic fibrosis transmembrane conductance regulator by nasal aminoglycosides in patients with cystic fibrosis with stop mutations.
  17347447 American journal of respiratory cell and molecular biology, 2007 July : 57-66
• Kulich M, Rosenfeld M, Campbell J, Kronmal R, Gibson RL, Goss CH, Ramsey B
  Disease-specific reference equations for lung function in patients with cystic fibrosis.
  15976373 American journal of respiratory and critical care medicine, 2005 Oct. 1 : 172(7)885-91
• Kulich M, Rosenfeld M, Campbell J, Kronmal R, Gibson RL, Goss CH, Ramsey B
  Disease-specific reference equations for lung function in patients with cystic fibrosis.
  15976373 American journal of respiratory and critical care medicine, 2005 Oct. 1 : 885-91
• Deterding R, Retsch-Bogart G, Milgram L, Gibson R, Daines C, Zeitlin PL, Milla C, Marshall B, Lavange L, Engels J, Mathews D, Gorden J, Schaberg A, Williams J, Ramsey B
  Safety and tolerability of denufosol tetrasodium inhalation solution, a novel P2Y2 receptor agonist: results of a phase 1/phase 2 multicenter study in mild to moderate cystic fibrosis.
  15704203 Pediatric pulmonology, 2005 April : 339-48