Margarett Shnorhavorian, MD, MPH

Margarett Shnorhavorian, MD, MPH

Urology, Differences in Sex Development, Fertility Preservation Program, Congenital Adrenal Hyperplasia Program, Vascular Anomalies, Fetal Care and Treatment Center

On staff since July 2006

Children's Title: Surgical Director, DSD Program; Surgical Director, CAH Program; Director, Research Division of Urology

Academic Title: Professor, Urology; Director, Clinical Research

Research Center: Center for Clinical and Translational Research

  • Dr. Margarett Shnorhavorian is a Professor of Urology at the University of Washington and a board certified pediatric urologist at Seattle Children’s Hospital. She is the Surgical Director of the Seattle Children’s Hospital Differences in Sex Development Program and Co-Surgical Director of the SCH level-1 CAH Comprehensive Care Center of Excellence designate by the CAH CARES Foundation.  Dr. Shnorhavorian is Principal Investigator for an R01 grant from the National Institutes of Health (NIH) examining the reproductive health of childhood cancer survivors (1R01CA175216 - 01A). She has completed an NIH Career Development K-Award for Male Reproductive Health Research

    She received her bachelor’s degree from University of California Los Angeles, where she graduated Phi Beta Kappa. She received her MD degree from the University of California, San Francisco, during which time she also received a Master’s in Public Health at the University of California Berkeley. She then completed her general and urologic surgery training at Yale University School of Medicine, followed by a fellowship in pediatric urology at the University of Washington.

    Dr. Shnorhavorian’s clinical focus is on urogenital reconstruction, specifically for differences in sex development, congenital adrenal hyperplasia, hypospadias, and exstrophy. Her academic pursuits include bioethics, translational research, and fertility preservation. She has published in many journals, including the Journal of Pediatric Urology and the Journal of Clinical Oncology. She has led the Male Reproductive Health Task Force for the National Cancer Institute Children’s Oncology Group (COG). Dr. Shnorhavorian currently serves on the COG Steering Committee for Outcomes and Survivorship and the SPU Task Force for Differences in Sex Development.

    • Related Resources

    • Tara Seattle, WA 08.11.18

      Dr. Shnorhavorian just completed a delicate surgery on my daughter with a team of other doctors. She is very caring and I have always felt confident in her knowledge as a urologist. Dr. Shnorhavorian has gone above and beyond in making sure I understand what is going on with my daughter and the steps to treatment. I would highly recommend her and am so grateful to have such skilled doctors caring for my daughter.

    • Michele Gillette, WY 06.22.16

      Dr. Shnorhavorian has been my daughters doctor since she was 1. We trust and love her. She has been a straight shooter and a wonderful comfort. My daughter feels comfortable with her and we will be coming back all the way from Wyoming for my daughters surgery. We will always trust Dr. S with our baby girl.

    Recommend Margarett Shnorhavorian, MD, MPH
  • Award Name Award Description Awarded By Award Date
    SEATTLE TOP DOCTOR - 2022 Seattle Magazine 2022
    Top Doctor-Pediatric Urology Seattle Metropolitan Magazine 2019
    Top Doctor-Pediatric Urology Seattle Metropolitan Magazine 2018
    Top Doctors-Pediatric Urology Seattle Metropolitan Magazine 2017
    Odessa Brown Ken Feldman Award Nominee for Outstanding Service in Promoting Diversity, Seattle Children's Hospital, Disorders of Sex Development Program Seattle Children's Hospital 2016
    Prize Abstract Session Prize Abstract Session presentation American Urological Association National Meeting, Society of Pediatric Urology, "Fertility Preservation among Adolescent and Young Adult Cancer Survivors in the AYA HOPE Study," San Diego, California American Urological Association National Meeting, Society of Pediatric Urology May 13, 2013
    First Place Clinical Research Award Section on Urology, National Conference & Exhibition American Academy of Pediatrics 2012
    Southwest Oncology Group Young Investigator Award 2010
    COG-AFLAC Young Investigator Award in Adolescent and Young Adult Oncology 2009
    Male Reproductive Health Research Award NIH K-award 2008 - 2013

  • Manuscripts in Refereed Journals

    • Amies Oelschlager A, Symons J, Shnorhavorian M, Halbach S, Greenleaf K, Debiec K, Merguerian PA
      Prepubertal Vaginal Septum Resection for Obstructed Hemivagina Ipsilateral Renal Anomoly
      Journal of Pediatric and Adolescent Gynecology, 2017 April
    • Ellison JS, Shnorhavorian MS, Grady RW, Merguerian PA.
      "Impact of Concomitant Hernia Repair at time of Complete Primary Repair of Bladder Exstrophy
      Journal of Pediatric Urology, 2016
    • Ellison JS, Shnorhavorian MS, Willihnganz-Lawson K, Grady RW, Merguerian PA.
      "A Critical Appraisal of Continence in Bladder Exstrophy: Long-Term Outcomes of the Complete Primary Repair
      Journal of Pediatric Urology, 2016
    • Akhavan A, Richards M, Shnorhavorian M, Goldin A, Gow K, Merguerian PA
      Renal Cell Carcinoma in Children, Adolescents and Young Adults: A National Cancer Database Study
      25451825 J Urol, 2014 Nov. 4
    • Akhavan A, Shnorhavorian M, Garrison L, Merguerian PA
      Resource Utilization and Costs Associated with the Diagnostic Evaluation of Nonrefluxing, Primary Hydronephrosis in Infants
      24704116 J Urol, 2014 April
    • Smith AW, Bellizzi KM, Keegan THM, Zebrack B, Chen VW, Neale AV, Hamilton A, Shnorhavorian M, Lynch CF, and the AYA HOPE Study Collaborative Group
      Health-related Quality of Life of Adolescent and Young Adult Cancer Patients in the United States: the AYA HOPE study
      J Clinical Oncology, 2013 Feb. 21
    • Kenney LB, Cohen LE, Shnorhavorian M, Metzger M, Lockhart B, Hijiya N, Duffey-Lind E, Constine L, Green D, Meacham L
      Male Reproductive Health after Childhood, Adolsecent, and Young Adult Cancer: A Report from the Childrens Oncology Group
      J of Clinical Oncology, 2012 Sept. 20 : 30(27)3408-16
    • Shnorhavorian M, Kroon L, Jeffries H, Johnson R
      Creating a Standardized Process to Offer the Standard of Care: Continuous Process Improvement Methodology is Associated With Increased Rates of Sperm Cryopreservation Among Adolescent and Young Adult Males With Cancer
      J of Pediatr Hematol Oncol, 2012 Sept. 13
    • Belizzi, K, Smith A, Schmidt S, Keegan T, Zebrack B, Lynch C, Deapen D, Shnorhavorian M, Tompkins B, Simon M; and the Adolescent and Young Adult Health Outcomes and Patient Experience (AYA HOPE) Study Collaborative Group
      Positive and negative psychosocial impact of being diagnosed with cancer as an adolescent or young adult
      Cancer, 2012 March 13 : doi: 0.100
    • Moshiri M, Chapman T, Fechner PY, Dubinsky T, Shnorhavorian M, Osman S, Bhargava P, Katz DS
      Evaluation and Management of Disorders of Sex Development: Multidisciplinary Approach to a Complex Diagnosis
      RadioGraphics, 2012 : 32(6)1599-618
    • Shnorhavorian M
      Transitioning patients with Disorders of Sex Development to Adult Care: The Role of The Pediatric Urologist
      J Urol, 2012 : 188(3)700-1
    • Shnorhavorian M, Hidalgo-Tamola J, Koyle MA, Wessells H, Larison C, Goldin A
      Unintentional and sexual abuse related pediatric female genital trauma: A multi-institutional study of free-standing pediatric hospitals in the United States
      Pediatric Urology, 2012 : 80(2)417-22
    • Adam JP, Fechner P, Ramsdell LA, Badaru A, Grady R, Pagon RA, McCauley E, Cheng EY, Parisi MA, Shnorhavorian M
      Ambiguous Genitalia: What Prenatal Genetic Testing is Practical?
      Am J of Med Genet A, 2012 : 158A(6)1337-43
    • Shnorhavorian M, Jacobs, MA, Stearns G, Mingin G, Koyle MA
      Practice variation and clinical confusion regarding undescended testes and retractile testes among primary care respondents: A multi-regional survey study in the United States
      Pediatr Surg Intl, 2012 : 28(6)635-639
    • Shnorhavorian M, Johnson R, Shear SB, Wilfond BS
      Responding to Adolescents with Cancer who Refuse Sperm Banking: When "No" Should Not Be the Last Word
      J of Adolescent and Young Adult Oncology, 2012 : 1(3)
    • Zamilpa I, Koyle MA, Grady RW, Joyner BD, Shnorhavorian M, Lendvay TS
      Can we Rely on the Presence of Dextranomer-Hyaluronic Acid Copolymer Mounds on Ultrasound to Predict Vesicoureteral Reflux Resolution After Injection Therapy?
      J of Urology, 2011 : 185(6 Suppl)2536-41
    • Margarett Shnorhavorian, MD, MPH, Goldsby R, Chen Y, Raber S, Li L, Diefenbach K, Shnorhavorian M, Kadan-Lottick N, Kastronos F, Yasui Y, Stovall M, Oeffinger K, Sklar C, Armstrong GT, Robison LL, Diller L
      Survivors of Childhood Cancer Have Increased Risk of Gastrointestinal Complications Later in Life
      Gastroenterology, 2011 : 140(5)1464-7
    • Shnorhavorian M, Song K, Zamilpa I, Wiater B, Mitchell MM, Grady RW
      Spica casting compared to Bryant's traction after complete primary repair of exstrophy: safe and effective in a longitudinal cohort study.
      20639033 The Journal of urology, 2010 Aug. : 669-73
    • Sorensen MD, Koyle MA, Cowan CA, Zamilpa I, Shnorhavorian M, Lendvay TS
      Injection volumes of dextranomer/hyaluronic acid are increasing in the endoscopic management of vesicoureteral reflux.
      20140734 Pediatric surgery international, 2010 May : 509-13
    • Shnorhavorian M
      A rewarding experience for a pediatric urologist.
      20811860 Cancer treatment and research, 2010 : 485
    • Hidalgo-Tamola J, Shnorhavorian M, Koyle MA
      "Open" minimally invasive surgery in pediatric urology.
      19297251 Journal of pediatric urology, 2009 June : 221-7
    • Shnorhavorian M, Friedman DL, Koyle MA
      Genitourinary long-term outcomes for childhood cancer survivors.
      19239818 Current urology reports, 2009 March : 134-7
    • Lendvay TS, Shnorhavorian M,Grady RW
      Robotic-Assisted Laparoscopic Mitrofanoff Appendicovesicostomy and Antegrade Continent E
      Journal of Advanced Laparoendoscopic and Advanced Surgical Tech, 2008 April
    • Shnorhavorian M, Anderson KR
      Anatomic and physiologic considerations in ureteroscopy.
      15040397 The Urologic clinics of North America, 2004 Feb. : 15-20
    • Shnrorhavorian M
      Guide to a healthy pregnancy
      Ministry of Health of Armenia. Maternal and Child Health Campaign, 1996

    Book Chapters

    • Fechner, PY, Shnorhavorian M
      Disorders of Sex Development
      In "Urological Emergencies: A Practical Approach, 2nd Edition." H Wessells (ed.), 2013 : Springer23:305-312
    • Shnorhavorian M
      Oncofertility: Ethical, Legal, Social, and Medical Perspectives edited by Teresa K. Woodruff, Laurie Zoloth, Lisa Campo-Engelstein, and Sarah Rodriguez
      Springer, 2010
    • Shnorhavorian M
      Genitourinary long-term outcomes for childhood cancer survivors
      In: Pediatric Urology: Surgical Complications and Management, 2nd Edition (Wilcox D, Koyle M, Godbole P, eds.), 2nd Editio
    • Shnorhavorian M, Fechner P
      Disorders of Sexual Differentiation
      Avery's Diseases of the Newborn, Tenth edit97:1365-1387
    • Amies Oelschlager A, Shnorhavorian M
      Variation of Sex Differentiation
      Clinical Pediatric and Adolescent Gynecology, 2nd Editio

    Published Books, Videos, Software, etc.

    • Rowe CK, Shnorhavorian M, Block P, Ahn J, Merguerian PA
      Using Social Media for Patient Centered Outcomes: A Study of Genital Apprearance and Sexual Function in Adult Bladder Exstrophy Patients
      Journal of Pediatric Urology, 2018 July 9 : 14(4)322.e1-322.eg
      https://www.jpurol.com/article/S1477-5131(18)30338-3/fulltext
    • Ahn J, Shnorhavorian M, Katz C, Goldin AB, Merguerian PA
      Response to Re: Early Versus Delayed Closure of Bladder Exstrophy: A National Surgical Quality Improvement Program Pediatric Analysis
      Journal of Pediatric Urology, 2018 March 14 : PMCID:29580730
    • Ahn J, Shnorhavorian M, Katz C, Goldin AB, Merguerian PA
      Early Versus Delayed Closure of Bladder Exstrophy: A National Surgical Quality Improvement Program Pediatric Analysis
      Journal of Pediatric Urology, 2017 Dec. 15
    • Ahn J, Shnorhavorian M, Merguerian PA
      MP69-13 Does Preoperative Urine Culture Screening Reduce the Incidence of Postoperative Infections?
      Journal of Pediatric Urology
    • Shnrorhavorian M
      Fertility Preservation
      Seattle Children's Hospital

    Manuscripts Submitted

    • Akhavan A, Merguerian PA, Larison C, Goldin A, Shnorhavorian M
      Trends in the Rates of Pediatric Pyeloplasty for Ureteropelvic Junction Obstruction Over 19 Years: A PHIS Database Study
      Advances in Urology, 2014 April
    • Keegan T, Tao L, DeRouen M, Wu X, Prasad P, Lynch C, Shnorhavorian M, Zebrack B, Chu R, Harlan L, Smith A, Parsons H, and the AYA HOPE Study Collaborative Group
      Medical care in adolescents and young adult cancer survivors: what are the biggest access-related barriers?
      J Clinical Oncology, Submitted
    • Wasilewski-Masker K, Seidel KD, Leisenring W, Mertens AC, Shnorhavorian M, Ritenour CW, Stoval M, Green DM, Sklar CA, Armstrong GT, Robison LL, Meacham LR
      Male infertility in long-term survivors of pediatric neoplasms: A report from the Childhood Cancer Survivor Study
      Human Reproduction, Submitted
    • Su R, Merguerian P, Grady R, Shnorhavorian M
      Surgical Hypospadias After Exstrophy (SHAE): Management and Outcomes
      J of Urology, Submitted
    • Potosky A, Harlan L, Cress R, Hamilton A, Kato I, Keegan T, Keel G, Schwartz S, Seibel, N, Shnorhavorian M, West M, Wu, X, and the AYA HOPE Study Collaborative Group
      Use of Appropriate Initial Treatment Among Adolescents and Young Adults with Cancer: A Population-Based Study
      J Clinical Oncology, Submitted

    Published Abstracts

    • Shnorhavorian M, Charlesworth-Attie S, Wilder-Smith A, Cress R, Hamilton A, Kato I, Keegan T, Lynch C, Prasad P, Wu X, Harlan L , Schwartz S
      Fertility Preservation Among Adolescent and Young Adult Cancer Survivors in the AYA HOPE Study
      American Urological Association National Meeting, Society of Pediatric Urology, 2013 May 3 : San Diego,
    • Shnorhavorian M, Leisenring W, Goodman P, Friedman D, Stovall M, Meacham L, Chow E, Sklar C, Diller L, Ferrer F, Armstrong G, Neglia J, Robison L
      Long-Term Adverse Genito-Urinary (GU) Outcomes in Survivors of Childhood Cancer: A report from the Childhood Cancer Survivor Study (CCSS)
      American Urological Association National Meeting, Society of Pediatric Urology, 2013 May 3 : San Diego,
    • Su R, Adam M, Fechner P, Badaru A, Ramsdell L, Merguerian P, Shnorhavorian M
      External Masculinization Score (EMS) and the Success of Genetic Testing in a Cohort of 46, XY DSD Patients
      Podium, 1st Annual GME Research Day, Top Ten finalist research presentation, 2013 April
    • Su R, Merguerian P, Hidalgo J, Grady R, Lendvay T, Shnorhavorian M
      Long-term Lower Urinary Tract Outcomes in Boys After Early Treatment of Posterior Urethral Valves
      Poster, American Academy of Pediatrics, New Orleans, Louisiana, 2012 Oct.

    Other Publications

    • Routh JC, Dasgupta R, Chi YY, Shnorhavorian M, Tian J, Walterhouse DO, Breneman J, Wolden SL, Arndt CA, Hawkins DS, Rodeberg DA
      Impact of local control and surgical lymph node evaluation in localized paratesticular rhabdomyosarcoma: A report from the Children's Oncology Group Soft Tissue Sarcoma Committee.
      32525556 International journal of cancer, 2020 Dec. 1 : 147(11)3168-3176
    • Shnorhavorian M
      Navigating Differences/Disorders of Sex Development in 2020.
      32715867 The Journal of urology, 2020 Oct. : 204(4)647-648
    • Canalichio KL, Shnorhavorian M, Oelschlager AA, Ramsdell L, Fisher C, Adam MP, Fechner PY
      A non-surgical approach to 46,XY differences in sex development through hormonal suppression at puberty: a single-center case series study.
      32643049 Endocrine, 2020 Oct. : 70(1)170-177
    • Cannon S, Ahn J, Shnorhavorian M, Kieran K, Merguerian P
      Gender and Invited Authorship in the Journal of Pediatric Urology.
      32712130 Urology, 2020 July 24
    • Canalichio KL, Ahn J, Artigas P, Amies Oelschlager AE, Rowe C, Merguerian P, Shnorhavorian M
      Patient-reported outcomes in adult females with bladder exstrophy: A study of long-term sexual, reproductive and urinary outcomes using social media.
      32698983 Journal of pediatric urology, 2020 June 21
    • Hougen HY, Seideman CA, Adam MP, Amies Oelschlager AM, Fechner PY, Ramsell L, Shnorhavorian M, Squire A, Austin JC
      Congenital virilization of female infants recognized after pregnancies with retained levonorgestrel intrauterine devices.
      32265103 Journal of pediatric urology, 2020 April : 16(2)241-243
    • Berrondo C, Bettinger B, Katz CB, Bauer J, Shnorhavorian M, Zerr DM
      Validation of an Electronic Surveillance Algorithm to Identify Patients With Post-Operative Surgical Site Infections Using National Surgical Quality Improvement Program Pediatric Data.
      31886513 Journal of the Pediatric Infectious Diseases Society, 2019 Dec. 30
    • Berrondo C, Ahn JJ, Shnorhavorian M
      Pre-operative skin antisepsis with chlorhexidine gluconate baths and wipes does not prevent postoperative surgical site infection in outpatient pediatric urologic inguinal and scrotal surgery.
      31564588 Journal of pediatric urology, 2019 Dec. : 15(6)652.e1-652.e7
    • Timmermans S, Yang A, Gardner M, Keegan CE, Yashar BM, Fechner PY, Shnorhavorian M, Vilain E, Siminoff LA, Sandberg DE
      Gender destinies: assigning gender in Disorders of Sex Development-Intersex clinics.
      31225650 Sociology of health & illness, 2019 Nov. : 41(8)1520-1534
    • Sandberg DE, Gardner M, Kopec K, Urbanski M, Callens N, Keegan CE, Yashar BM, Fechner PY, Shnorhavorian M, Vilain E, Timmermans S, Siminoff LA
      Development of a decision support tool in pediatric Differences/Disorders of Sex Development.
      31668291 Seminars in pediatric surgery, 2019 Oct. : 28(5)150838 PMCID:PMC6911706
    • Ellison JS, Merguerian PA, Fu BC, Holt SK, Lendvay TS, Shnorhavorian M
      Postoperative Imaging Patterns of Pediatric Nephrolithiasis: Opportunities for Improvement.
      30316895 The Journal of urology, 2019 April : 201(4)794-801
    • Ellison JS, Merguerian PA, Fu BC, Holt SK, Lendvay TS, Gore JL, Shnorhavorian M
      Follow-up imaging after acute evaluations for pediatric nephrolithiasis: Trends from a National database.
      29866410 Journal of pediatric urology, 2018 Dec. : 14(6)525-531
    • Timmermans S, Yang A, Gardner M, Keegan CE, Yashar BM, Fechner PY, Shnorhavorian M, Vilain E, Siminoff LA, Sandberg DE
      Does Patient-centered Care Change Genital Surgery Decisions? The Strategic Use of Clinical Uncertainty in Disorders of Sex Development Clinics.
      30303019 Journal of health and social behavior, 2018 Dec. : 59(4)520-535
    • Kieran K, Shnorhavorian M
      Fertility Issues in Pediatric Urology.
      30316313 The Urologic clinics of North America, 2018 Nov. : 45(4)587-599
    • Walterhouse DO, Barkauskas DA, Hall D, Ferrari A, De Salvo GL, Koscielniak E, Stevens MCG, Martelli H, Seitz G, Rodeberg DA, Shnorhavorian M, Dasgupta R, Breneman JC, Anderson JR, Bergeron C, Bisogno G, Meyer WH, Hawkins DS, Minard-Colin V
      Demographic and Treatment Variables Influencing Outcome for Localized Paratesticular Rhabdomyosarcoma: Results From a Pooled Analysis of North American and European Cooperative Groups.
      30351998 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018 Oct. 23 : JCO2018789388 PMCID:PMC6286163
    • Hawkins DS, Chi YY, Anderson JR, Tian J, Arndt CAS, Bomgaars L, Donaldson SS, Hayes-Jordan A, Mascarenhas L, McCarville MB, McCune JS, McCowage G, Million L, Morris CD, Parham DM, Rodeberg DA, Rudzinski ER, Shnorhavorian M, Spunt SL, Skapek SX, Teot LA, Wolden S, Yock TI, Meyer WH
      Addition of Vincristine and Irinotecan to Vincristine, Dactinomycin, and Cyclophosphamide Does Not Improve Outcome for Intermediate-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group.
      30091945 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018 Sept. 20 : 36(27)2770-2777 PMCID:PMC6145831
    • Ahn JJ, Merguerian PA, Shnorhavorian M
      Incidence and risk factors associated with 30-day post-operative venous thromboembolism: A NSQIP-pediatric analysis.
      29784455 Journal of pediatric urology, 2018 Aug. : 14(4)335.e1-335.e6
    • Ellison JS, Shnorhavorian M, Oron A, Kieran K, Lendvay TS, Merguerian PA
      Risk factors for repeat surgical intervention in pediatric nephrolithiasis: A Pediatric Health Information System database study.
      29580730 Journal of pediatric urology, 2018 June : 14(3)245.e1-245.e6
    • Ellison JS, Hollingsworth JM, Langman CB, Asplin JR, Schwaderer AL, Yan P, Bierlein M, Barraza MA, Defoor WR, Figueroa TE, Jackson EC, Jayanthi VR, Johnson EK, Joseph DB, Shnorhavorian M
      Analyte variations in consecutive 24-hour urine collections in children.
      28739373 Journal of pediatric urology, 2017 Dec. : 13(6)632.e1-632.e7
    • Ellison JS, Merguerian PA, Fu BC, Holt SK, Lendvay TS, Gore JL, Shnorhavorian M
      Use of medical expulsive therapy in children: An assessment of nationwide practice patterns and outcomes.
      28483465 Journal of pediatric urology, 2017 Oct. : 13(5)509.e1-509.e7 PMCID:PMC5947996
    • Ahn JJ, Shnorhavorian M, Amies Oelschlager AE, Ripley B, Shivaram GM, Avansino JR, Merguerian PA
      Use of 3D reconstruction cloacagrams and 3D printing in cloacal malformations.
      28673795 Journal of pediatric urology, 2017 Aug. : 13(4)395.e1-395.e6
    • Ellison JS, Ahn J, Shnorhavorian M, Grady R, Merguerian PA
      Long-term fate of the upper tracts following complete primary repair of bladder exstrophy.
      28592391 Journal of pediatric urology, 2017 Aug. : 13(4)394.e1-394.e6
    • Shnohavorian M
      Navigating Surgical Management in Patients with Differences in Sex development
      2017 13th Annual Pediatrics Bioethics Conference, “The Cutting Edge: Ethical Controversies in Pediatric Surgery, 2017
    • Byers HM, Mohnach LH, Fechner PY, Chen M, Thomas IH, Ramsdell LA, Shnorhavorian M, McCauley EA, Amies Oelschlager AE, Park JM, Sandberg DE, Adam MP, Keegan CE
      Unexpected ethical dilemmas in sex assignment in 46,XY DSD due to 5-alpha reductase type 2 deficiency.
      28544750 American journal of medical genetics. Part C, Seminars in medical genetics, 2017 June : 175(2)260-267 PMCID:PMC5489130
    • Cost NG, Ross JH, Ferrer FA, Lorenzo AJ, Shnorhavorian M, Routh JC, Kieran K, Ritchey ML
      Patterns of Performance of Oncologic Surgery by North American Pediatric Urologists: A Report from the Pediatric Urologic Oncology Working Group of the Society for Pediatric Urology.
      27986529 The Journal of urology, 2017 May : 197(5)1349-1354
    • Cost NG, Ferrer FA, Lorenzo AJ, Shnorhavorian M, Kieran K, Routh JC, Ritchey ML, Ross JH
      A Society for Pediatric Urology Workforce Survey on the Current Perceptions of Oncology Care by Pediatric Urologists: A Report from the Pediatric Urologic Oncology Working Group of the Society for Pediatric Urology.
      27837647 The Journal of urology, 2017 March : 197(3 Pt 2)892-897
    • Skinner R, Mulder RL, Kremer LC, Hudson MM, Constine LS, Bardi E, Boekhout A, Borgmann-Staudt A, Brown MC, Cohn R, Dirksen U, Giwercman A, Ishiguro H, Jahnukainen K, Kenney LB, Loonen JJ, Meacham L, Neggers S, Nussey S, Petersen C, Shnorhavorian M, van den Heuvel-Eibrink MM, van Santen HM, Wallace WH, Green DM
      Recommendations for gonadotoxicity surveillance in male childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consortium.
      28214419 The Lancet. Oncology, 2017 Feb. : 18(2)e75-e90
    • Shnorhavorian M, Schwartz SM, Stansfeld B, Sadler-Riggleman I, Beck D, Skinner MK
      Differential DNA Methylation Regions in Adult Human Sperm following Adolescent Chemotherapy: Potential for Epigenetic Inheritance.
      28146567 PloS one, 2017 : 12(2)e0170085 PMCID:PMC5287489
    • Shnorhavorian M, Doody DR, Chen VW, Hamilton AS, Kato I, Cress RD, West M, Wu XC, Keegan TH, Harlan LC, Schwartz SM, AYA HOPE Study Collaborative Group.
      Knowledge of Clinical Trial Availability and Reasons for Nonparticipation Among Adolescent and Young Adult Cancer Patients: A Population-based Study.
      27635619 American journal of clinical oncology, 2016 Sept. 15
    • Ellison JS, Shnorhavorian M, Merguerian PA, Grady R
      Impact of concomitant hernia repair at the time of complete primary repair of bladder exstrophy.
      27264049 Journal of pediatric urology, 2016 Aug. : 12(4)211.e1-5
    • Ritenour CW, Seidel KD, Leisenring W, Mertens AC, Wasilewski-Masker K, Shnorhavorian M, Sklar CA, Whitton JA, Stovall M, Constine LS, Armstrong GT, Robison LL, Meacham LR
      Erectile Dysfunction in Male Survivors of Childhood Cancer-A Report From the Childhood Cancer Survivor Study.
      27117527 The journal of sexual medicine, 2016 June : 13(6)945-54 PMCID:PMC4879056
    • Chow EJ, Stratton KL, Leisenring WM, Oeffinger KC, Sklar CA, Donaldson SS, Ginsberg JP, Kenney LB, Levine JM, Robison LL, Shnorhavorian M, Stovall M, Armstrong GT, Green DM
      Pregnancy after chemotherapy in male and female survivors of childhood cancer treated between 1970 and 1999: a report from the Childhood Cancer Survivor Study cohort.
      27020005 The Lancet. Oncology, 2016 May : 17(5)567-76 PMCID:PMC4907859
    • Kieran K, Shnorhavorian M
      Current standards of care in bladder and prostate rhabdomyosarcoma.
      26776454 Urologic oncology, 2016 Feb. : 34(2)93-102
    • Finlayson C, Johnson EK, Chen D, Dabrowski E, Gosiengfiao Y, Campo-Engelstein L, Rosoklija I, Jacobson J, Shnorhavorian M, Pavone ME, Moravek MB, Bonifacio HJ, Simons L, Hudson J, Fechner PY, Gomez-Lobo V, Kadakia R, Shurba A, Rowell E, Woodruff TK
      Proceedings of the Working Group Session on Fertility Preservation for Individuals with Gender and Sex Diversity.
      28111635 Transgender health, 2016 : 1(1)99-107 PMCID:PMC5243122
    • Willihnganz-Lawson K, Gordon J, Perkins J, Shnorhavorian M
      Genitourinary and perineal vascular anomalies in children: A Seattle children's experience.
      26163459 Journal of pediatric urology, 2015 Aug. : 11(4)227.e1-6
    • Dy GW, Willihnganz-Lawson KH, Shnorhavorian M, Delaney SS, Amies Oelschlager AM, Merguerian PA, Grady R, Miller JL, Cheng EY
      Successful pregnancy in patients with exstrophy-epispadias complex: A University of Washington experience.
      26092092 Journal of pediatric urology, 2015 Aug. : 11(4)213.e1-6
    • Ginsberg JP, Li Y, Carlson CA, Gracia CR, Hobbie WL, Miller VA, Mulhall J, Shnorhavorian M, Brinster RL, Kolon TF
      Testicular tissue cryopreservation in prepubertal male children: an analysis of parental decision-making.
      24777742 Pediatric blood & cancer, 2014 Sept. : 61(9)1673-8 PMCID:PMC4676076
    • Keegan TH, Tao L, Derouen MC, Wu XC, Prasad P, Lynch CF, Shnorhavorian M, Zebrack BJ, Chu R, Harlan LC, Smith AW, Parsons HM, AYA HOPE Study Collaborative Group
      Medical care in adolescents and young adult cancer survivors: what are the biggest access-related barriers?
      24408440 Journal of cancer survivorship : research and practice, 2014 Jan. 10
    • Akhavan A, Merguerian PA, Grady RW, Disandro M, Shnorhavorian M
      Digital photographic measurement in hypospadias: Validation and comparison to intraoperative measurement.
      24291248 Journal of pediatric urology, 2013 Nov. 7
    • Wilson CL, Ness KK, Neglia JP, Hammond S, Shnorhavorian M, Leisenring WL, Stovall M, Robison LL, Armstrong GT
      Renal carcinoma after childhood cancer: a report from the childhood cancer survivor study.
      23515901 Journal of the National Cancer Institute, 2013 April 3 : 105(7)504-8 PMCID:PMC3691945
    • Shnorhavorian M, Bittner R, Wright JL, Schwartz SM
      Maternal risk factors for congenital urinary anomalies: results of a population-based case-control study.
      22054394 Urology, 2011 Nov. : 78(5)1156-61
    • Vemulakonda VM, Lendvay TS, Shnorhavorian M, Joyner BD, Kaplan H, Mitchell ME, Grady RW
      Metastatic adenocarcinoma after augmentation gastrocystoplasty.
      18206936 The Journal of urology, 2008 March : 179(3)1094-6; discussion 1097
    • Shnrorhavorian M
      Testes guidelines
    • Shnrorhavorian M
      Long Term Follow-up Guidelines
      Children’s Oncology Group 2010
    • Shnrorhavorian M
      Seattle Children's Hospital DSD 2014
      Seattle Children's Hospital
    • Shnrorhavorian M
      Sub-ethnicity: Armenians in Los Angeles
      World Bank Report on Development in Armenia
    • Differences in Sex Development Program Website
      Seattle Children's Hospital
    • Shnrorhavorian M
      UCLA Center for Health Promotion and Disease Prevention
      HIV/AIDS: A Manual for Health Professionals, 1994
    • Shnrorhavorian M
      Late urinary effects guidelines

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  • Presentations Title Event Location Date
    Survey on current practice in antibiotic prophylaxis prior to ureteral stent removal American Urological Association Annual Meeting Chicago, IL May 4, 2019
    MP69-13 Does Preoperative Urine Culture Screening reduce the incidence of postoperative infections? American Urological Association Annual Meeting San Francisco, CA May 18, 2018 - 2018
    “Boys to Men: Male fertility preservation”. 2017 Oncofertility Conference, “Research and Translational Medicine: Meeting the needs of cancer patients and survivors”. Chicago, IL (CME Course) Nov. 15, 2017
    Incidence and Risk Factors associated with Post-operative Venous Thromboembolism: A NSQIP-Pediatric Analysis Pediatric Urology Fall Congress Meeting Montreal, Canada Sept. 2017
    “Navigating Surgical Management in Patients with Differences in Sex Development”. ”Seattle Children's Hospital 13th Annual Pediatric Bioethics Conference, “The Cutting Edge: Ethical Controversies in Pediatric Surgery Seattle, WA July 22, 2017
    Early versus delayed closure of Bladder Exstrophy: A NSQIP Pediatric Analysis. American College of Surgeons Quality and Safety Conference Washington, DC July 2017
    MP66-17: Risk factors for repeat surgical intervention in pediatric nephrolithiasis: A pediatric health information system database study American Urological Association Annual Meeting Boston, MA May 2017
    MP66-11 Follow-up imaging patterns after emergency department visits for pediatric nephrolithiasis American Urological Association Annual Meeting Boston, MA 2017
    Early versus delayed closure of Bladder Exstrophy: A NSQIP Pediatric Analysis American Urological Association Annual Meeting Boston, MA May 2017
    “Utilization of Medical Expulsive Therapy: An Assessment of Nationwide Practice Patterns and Outcomes”. 2016 American Urological Association Annual Meeting San Diego, CA May 2016
    “Variation in consecutive 24-hour urine studies in pediatric patients”. 2016 American Urological Association Annual Meeting-Awarded best poster in session. San Diego, CA May 2016
    "National Trends in Resource Utilization for the Management of Antenatal Hydronephrosis". American Urological Association Annual Meeting 2016 San Diego,CA 2016
    "Variation in Consecutive 24-Hour Urine Studies in Pediatric Patients". American Urological Association Annual Meeting 2016 San Diego, CA 2016
    DSD Ethics of Genital Surgery Nationwide Childrens Hospital Thrive Conference Colombus, Ohio Nov. 7, 2015
    “Differences of Sex Development Ethics of Genital Surgery.” Biopsychosocial approach to sex development and gender regional conference, Nationwide Children’s Hospital Columbus, OH Nov. 4, 2015
    "A Critical Appraisal of Continence In Bladder Exstrophy: Long-Term Outcomes of the Complete Primary Repair". SPU Fall Congress Prague,CZ 2015
    "Impact of Concomitant Inguinal Hernia Repair at Time of Initial Exstrophy Repair". SPU Fall Congress Prague,CZ 2015
    Late Effects after Treatment of Childhood Malignancies American Urological Association 2014 Plenary Program State-of-the Art Lecture Orlando, FL May 18, 2014
    Moderator: Society of Pediatric Urology Panel on Legal and Ethical Issues in DSD American Urological Association Orlando, FL May 17, 2014
    Update from the DSD TRN Anatomy Workgroup " NIH DSD Translational Research Network and Advocacy Advisory Network Annual Meeting, American College of Surgeons Phoenix, AZ May 1, 2014 - May 4, 2014
    Whats in a name? Standardizing the Anatomic Evaluation of DSD NICHD Scientific Research Workshop, Diagnostic Factors Associated with Quality of Life Outcomes at Different Development Stages in DSD National Institute of Health (NIH), Bethesda, MD March 26, 2014
    Are genetic variants that influence testicular cancer risk also involved in hypospadias and undescended testes? A case-parent study Pediatric Urology Fall Congress Las Vegas, Nevada Sept. 20, 2013
    From Cancer to Wellness: Fertility Preservation Cancer Survivorship Symposium, Seattle Childrens Hospital Seattle, Washington Oct. 27, 2012
    Curbside consultation in urology North American Society of Pediatric and Adolescent Gynecology National Meeting Miami, FL April 2012
    Common urologic problems in girls and adolescents North American Society of Pediatric and Adolescent Gynecology National Meeting Miami, Florida April 2012
    What’s in a name? Standardizing the anatomic evaluation of DSD. NICHD Scientific research workshop, Diagnostic factors associated with quality of life outcomes at different development stages in DSD. National institute of health (NIH), Bethesda, MD April 2012
    Pediatric Urology for the primary care provider Providence Physician Group Mill Creek, Washington Jan. 31, 2012
    Ups and Downs of Testes: Evaluation and Management of Undescended Testes Clinicians Guide to Pediatric Urology: A Practical Update. Seattle Childrens Hospital, CME Level I Seattle, Washington Nov. 19, 2011
    Modern Surgical Management of Urogenital Sinus and Cloaca Pediatric Surgery Department Conference, Hue Central Hospital Hue, Vietnam Oct. 2011
    Seattle Childrens Hospital Center for Clinical and Translational Research External Review Research Presentation Seattle, Washington Sept. 19, 2011
    Outcomes in Reproduction in Childhood and Adolescent Survivors: ORCAS an update Male Reproductive Health Research Award Symposium, University of Washington Seattle, Washington April 6, 2011
    Disorders of Sex development: Consensus and Controversy Pediatric Urology Conference Seattle Children's Hospital Feb. 14, 2011
    Evaluation and Surgical Management of Ambiguous Genitalia Department of Pediatric Surgery Grand Rounds, Hue Central Hospital Hue, Vietnam 2011
    Complex Hypospadias Reconstruction Modern Techniques Department of Urology Grand Rounds, Hue Central Hospital Hue, Vietnam 2011
    DSD - Multidisciplinary Approach Department of Urology Conference University of Washington 2011
    Challenging DSD Cases Department of Urology Conference University of Washington 2011
    Consensus and Controversies in the Surgical Management of Patients with DSD Seattle Childrens Hospital, CME Level I and North American Society of Androgen Insensitivity Syndrome Support Group-USA Seattle, Washington 2011
    DSD Department of Urology Conference University of Washington 2011
    Moving Beyond Cancer to Wellness: Male Fertility Preservation Fertility Breakout Session, Lance Armstrong Foundation, Cancer Care Alliance Seattle, Washington Nov. 6, 2010
    Outcomes in Reproduction in Childhood and Adolescent Survivors Seattle Childrens Hospital Grand Rounds Seattle, Washington Sept. 30, 2010
    Patient Acquired Images in Pediatric Postoperative Care Results in Reduction of Unnecessary Emergency Department Visits American Academy of Pediatrics (AAP) National Conference and Exhibition Washington, DC Oct. 18, 2009
    Emerging guidelines from the Childrens Oncology Group (COG) Yale Surgical Society Grand Rounds, Division of Urology New Haven, CT June 5, 2009
    LH and FSH Are Significantly Elevated in Young Men After Treatment with Ifosfamide and Cyclophosphamide in Relation to the Total Dose of Chemotherapy American Academy of Pediatrics, Section on Urology Annual Meeting Washington, DC 2009
    Surgical management of intersexuality, cloacal malformation and anomalies of genitalia in girls Department of Urology Conference University of Washington 2009
  • Grant Title Grantor Amount Award Date
    Decision support for parents receiving genetic information about childs rare disease Patient Centered Outcomes Research Institute (PCORI) $1,373,164 Jan. 1, 2013 - Dec. 31, 2015
    Mens Reproductive Health Research at the University of Washington/K12 Training program NIH/NICHD 1,603,944 2012 - 2017
    Disorder of Sex Development: Platform for Basic and Translational Research NIH $4,000,000 Sept. 26, 2011 - June 30, 2016
    Outcomes in Reproduction for Childhood and Adolescent Survivors Rally Foundation $5,000 May 1, 2010 - March 31, 2011
    Hypospadias, undescended testes, Testes tumors (HUT): A DNA banking study University of Washington/Seattle Childrens Hospital $40,000 2010
    Outcomes in Reproduction after Cisplatin in Adolescent Survivors (ORCAS) Childrens Oncology Group (COG) and AFLAC, National Childrens Cancer Foundation Fund $60,000 Jan. 1, 2010 - Dec. 31, 2011
    Genes Involved in Male Reproductive Tract Anomalies and the Risk of Testis Cancer: A Candidate Genetic Polymorphism Study. Seattle Childrens Center for Clinical and Translational Research $20,000 Sept. 1, 2009 - Aug. 31, 2010
    Outcomes in Reproduction for Childhood and Adolescent Survivors: A study of the effects of Ifosfamide Seattle Childrens Clinical and Translational Research Center $40,000 Sept. 1, 2008 - Aug. 31, 2010
    Quality of Life in Intersexuality: A Pediatric Clinical and Research Tool National Institute of Child Health and Human Development April 1, 2008 - March 31, 2011
    Health-related quality of Life: A pediatric clinical and research tool National Institute of Child Health and Human Development April 1, 2008 - March 31, 2011
    Feasibility of Expended Patterns of Care Study of AYA Cancers (AYA HOPE) NIH/NCI 93,964 2007 - 2010
    Childhood Cancer Survivor Study (CCSS) National Cancer Institute Sept. 1, 1993 - Nov. 30, 2010
    Testicular effects of modern chemotherapy regimens in osteosarcoma survivors National Cancer Institute (NCI) Scientific Review Group: Epidemiology of Cancer Study Section (EPIC) $3,934.654 /5 years
    Disorders/Differences of Sex Development (DSD)-Translational Research National Institutes of Health $187,500 2023

Overview

Board Certification(s)

Pediatric Urology
Urology

Medical/Professional School

University of California Berkeley, Berkeley, CA
University of California San Francisco School of Medicine, San Francisco, CA

Residency

YSR Internal Medicine Residency Program, New Haven, CT

Fellowship

University of Washington School of Medicine, Seattle, WA

Clinical Interests

Urogenital reconstruction, specifically for differences in sex development, congenital adrenal hyperplasia, hypospadias, and exstrophy.

Research Description

Dr. Shnorhavorian is Principal Investigator for an R01 grant from the National Institutes of Health (NIH) examining the reproductive health of childhood cancer survivors (1R01CA175216 - 01A). She has completed an NIH Career Development K-Award for Male Reproductive Health Research.

Research Focus Area

Epidemiology, Refractory and recurrent cancer, Sarcomas, Thyroid Cancer, Cancer biology, Cancer