Kenneth A Schenkman, MD, PhD
Critical Care, Pediatric Intensive Care Unit (PICU)
On staff since November 1998
Academic Title: Associate Professor
Research Center: Center for Clinical and Translational Research
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Kenneth A. Schenkman, MD, PhD, is an attending physician in the Pediatric Intensive Care Units at Seattle Childrens Hospital and Harborview Medical Center. He is an Associate Professor of Pediatrics and Anesthesiology and Adjunct Associate Professor of Bioengineering at the University of Washington School of Medicine. Dr. Schenkman received his MD from Indiana University and completed a pediatrics residency at the Childrens Hospital of Pittsburgh, where he also served as Chief Resident.
Dr. Schenkman trained in pediatric critical care at Seattle Childrens and received a PhD in Bioengineering from the University of Washington. He has an active research program developing optical spectroscopic technologies for clinical assessment of intracellular oxygenation and mitochondrial function. Dr. Schenkman has several U.S. patents for his pioneering work on developing an intracellular oxygen monitor. Schenkman has published dozens of manuscripts and abstracts in the field of optical spectroscopy for physiologic and clinical applications, and has published several book chapters on pediatric critical care topics. He also has been an active reviewer for journals in the fields of medicine, physiology and biomedical optics.
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Manuscripts in Refereed Journals
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Kenneth A. Schenkman, MD, PhDPhoton Path Depth in Tissue Phantoms: A Comparison of Visible and Near-Infrared Wavelengths
Proceedings of the SPIE Symposium on Biomedical Optics, 2014 : 8945 -
Kenneth A. Schenkman, MD, PhDMuscle oxygenation measurement in humans by noninvasive optical spectroscopy and locally weight regression
Analytica Chimica Acta, 2013 : 78527-33 PMCID:490057 -
Cohen GA, Permut LC, Arakaki LS, Ciesielski WA, McMullan DM, Parrish AR, Schenkman KADirect optical measurement of intraoperative myocardial oxygenation during congenital heart surgery.
21508828 ASAIO journal (American Society for Artificial Internal Organs : 1992), 2011 July : 57(4)314-7
Other Publications
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Arakaki LS, Schenkman KA, Ciesielski WA, Shaver JMMuscle oxygenation measurement in humans by noninvasive optical spectroscopy and Locally Weighted Regression.
23764440 Analytica chimica acta, 2013 Jun 27 : 78527-33 PMCID:PMC3772676 -
Arakaki LS, Schenkman KA, Ciesielski WA, Shaver JMMuscle oxygenation measurement in humans by noninvasive optical spectroscopy and Locally Weighted Regression.
23764440 Analytica chimica acta, 2013 Jun 27 : 78527-33 PMCID:PMC3772676 -
Cohen GA, Permut LC, Arakaki LS, Ciesielski WA, McMullan DM, Parrish AR, Schenkman KADirect optical measurement of intraoperative myocardial oxygenation during congenital heart surgery.
21508828 ASAIO journal (American Society for Artificial Internal Organs : 1992), 2011 July : 314-7 -
Arakaki LS, Ciesielski WA, Thackray BD, Feigl EO, Schenkman KASimultaneous optical spectroscopic measurement of hemoglobin and myoglobin saturations and cytochrome aa3 oxidation in vivo.
20828433 Applied spectroscopy, 2010 Sept. : 973-9 -
Amara CE, Marcinek DJ, Shankland EG, Schenkman KA, Arakaki LS, Conley KEMitochondrial function in vivo: spectroscopy provides window on cellular energetics.
18930151 Methods (San Diego, Calif.), 2008 Dec. : 312-8 -
Amara CE, Marcinek DJ, Shankland EG, Schenkman KA, Arakaki LS, Conley KEMitochondrial function in vivo: spectroscopy provides window on cellular energetics.
18930151 Methods (San Diego, Calif.), 2008 Dec. : 312-8 -
Kruse SE, Watt WC, Marcinek DJ, Kapur RP, Schenkman KA, Palmiter RDMice with mitochondrial complex I deficiency develop a fatal encephalomyopathy.
18396137 Cell metabolism, 2008 April : 312-20 -
Schenkman KAClinical data collection in the information era.
17989567 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2007 Nov. : 588-9 -
Schenkman KAClinical data collection in the information era.
17989567 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2007 Nov. : 588-9 -
Marcinek DJ, Amara CE, Matz K, Conley KE, Schenkman KAWavelength shift analysis: a simple method to determine the contribution of hemoglobin and myoglobin to in vivo optical spectra.
17650380 Applied spectroscopy, 2007 June : 665-9 -
Schenkman KA, Arakaki LS, Ciesielski WA, Beard DAOptical spectroscopy demonstrates elevated intracellular oxygenation in an endotoxic model of sepsis in the perfused heart.
17505311 Shock (Augusta, Ga.), 2007 June : 695-700 -
Roberts JS, Vavilala MS, Schenkman KA, Shaw D, Martin LD, Lam AMCerebral hyperemia and impaired cerebral autoregulation associated with diabetic ketoacidosis in critically ill children.
16763506 Critical care medicine, 2006 Aug. : 2217-23 -
Ejike JC, Schenkman KA, Seidel K, Ramamoorthy C, Roberts JSCerebral oxygenation in neonatal and pediatric patients during veno-arterial extracorporeal life support.
16446597 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2006 March : 154-8 -
Marcinek DJ, Schenkman KA, Ciesielski WA, Lee D, Conley KEReduced mitochondrial coupling in vivo alters cellular energetics in aged mouse skeletal muscle.
16254011 The Journal of physiology, 2005 Dec 1 : 467-73 -
Ejike JC, Arakaki LS, Beard DA, Ciesielski WA, Feigl EO, Schenkman KAMyocardial oxygenation and adenosine release in isolated guinea pig hearts during changes in contractility.
15591100 American journal of physiology. Heart and circulatory physiology, 2005 May : H2062-7 -
Ejike JC, Arakaki LS, Beard DA, Ciesielski WA, Feigl EO, Schenkman KAMyocardial oxygenation and adenosine release in isolated guinea pig hearts during changes in contractility.
15591100 American journal of physiology. Heart and circulatory physiology, 2005 May : H2062-7 -
Marcinek DJ, Schenkman KA, Ciesielski WA, Conley KEMitochondrial coupling in vivo in mouse skeletal muscle.
14522819 American journal of physiology. Cell physiology, 2004 Feb. : C457-63 -
Schenkman KA, Beard DA, Ciesielski WA, Feigl EOComparison of buffer and red blood cell perfusion of guinea pig heart oxygenation.
12869374 American journal of physiology. Heart and circulatory physiology, 2003 Nov. : H1819-25 -
Beard DA, Schenkman KA, Feigl EOMyocardial oxygenation in isolated hearts predicted by an anatomically realistic microvascular transport model.
12869375 American journal of physiology. Heart and circulatory physiology, 2003 Nov. : H1826-36 -
Schenkman KA, Beard DA, Ciesielski WA, Feigl EOComparison of buffer and red blood cell perfusion of guinea pig heart oxygenation.
12869374 American journal of physiology. Heart and circulatory physiology, 2003 Nov. : H1819-25 -
Beard DA, Schenkman KA, Feigl EOMyocardial oxygenation in isolated hearts predicted by an anatomically realistic microvascular transport model.
12869375 American journal of physiology. Heart and circulatory physiology, 2003 Nov. : H1826-36 -
Marcinek DJ, Ciesielski WA, Conley KE, Schenkman KAOxygen regulation and limitation to cellular respiration in mouse skeletal muscle in vivo.
12775561 American journal of physiology. Heart and circulatory physiology, 2003 Nov. : H1900-8 -
Marcinek DJ, Ciesielski WA, Conley KE, Schenkman KAOxygen regulation and limitation to cellular respiration in mouse skeletal muscle in vivo.
12775561 American journal of physiology. Heart and circulatory physiology, 2003 Nov. : H1900-8 -
Okpechi JC, Schenkman KABronchoesophageal fistula after gastrostomy tube removal by the "cut and push" method.
12838242 Gastrointestinal endoscopy, 2003 July : 134-7 -
Okpechi JC, Schenkman KABronchoesophageal fistula after gastrostomy tube removal by the "cut and push" method.
12838242 Gastrointestinal endoscopy, 2003 July : 134-7 -
Maier SK, Westenbroek RE, Schenkman KA, Feigl EO, Scheuer T, Catterall WAAn unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart.
11891345 Proceedings of the National Academy of Sciences of the United States of America, 2002 Mar 19 : 4073-8 -
Sweet IR, Khalil G, Wallen AR, Steedman M, Schenkman KA, Reems JA, Kahn SE, Callis JBContinuous measurement of oxygen consumption by pancreatic islets.
12450449 Diabetes technology & therapeutics, 2002 : 661-72
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Grant Title Grantor Amount Award Date Assessment of muscle oxygen consumption in children with congenital heart disease UW Royalty Research Fund $39,736 2015 - 2016 Muscle oxygenation as an indicator for red blood cell transfusion need CCTR TRIPP $50,000 2013 - 2014 Muscle oxygenation for assessment of tissue perfusion during extracorporeal life support American Heart Association $140,000 2013 - 2014 Development of an instrument to track oxygen from blood to mitochondria in vivo NIH $563,025 2013 - 2016 Optical measurement of cellular oxygenation in shock and resuscitation NIH $429,000 2010 - 2012 Noninvasive cellular oxygen monitor for shock Coulter Foundation $55,127.00 2009 - 2010 Translational center for in vivo mitochondrial medicine NIH $1,798,509.00 2009 - 2011 Noninvasive Clinical Monitor for Early Detection of Shock WA Life Sciences Discovery Fund $150,000.00 2009 - 2010 Cellular oxygenation in traumatic shock Seattle Medic One Foundation, $106,291.00 2009 - 2010 Noninvasive shock monitor for trauma and critically ill patients UW Technology Gap Innovation Fund $50,000.00 2008 - 2009 MR and optical diagnosis of muscle metabolism and function NIH $1,678,900.00 2007 - 2012
Overview
- Board Certification(s)
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Pediatric Critical Care Medicine
- Medical/Professional School
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Indiana Univ/Purdue University-Indianapolis, Indianapolis, IN
University of Washington, Seattle, WA - Residency
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Children's Hospital of Pittsburgh, Pittsburgh, PA
- Fellowship
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Seattle Children's Hospital, Seattle, WA
- Research Focus Area
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Translational research, observational studies, investigator-initiated interventional studies, Therapeutic Trials