Kendra M Smith, MD

Kendra M Smith, MD

Neonatology, Bronchopulmonary Dysplasia Program

On staff since February 2001

Children's Title: Member Extracorporeal Life Support Steering Committee

Academic Title: Clinical Professor, Pediatrics

Research Center: Center for Integrative Brain Research

"I find great joy in taking care of babies and seeing their bright little faces as they see the world for the very first time, in going home after an arduous day knowing that I’ve made a difference in a patient’s life, in truly connecting with a family, and in being surrounded by a team of physicians, nurses, RTs, social workers and discharge coordinators who can make miracles happen in a crisis. In my career I work on promoting improved ventilation strategies for neonates requiring ventilatory support in our region."

  • Biography

    In conjunction with her clinical interests, Dr. Kendra Smith is the principle investigator for two industry-sponsored clinical studies looking at improving the outcome of infants with persistent pulmonary hypertension. She is also working with liquid assisted ventilation to better protect the lungs in neonates severely ill requiring the respirator or extracorporeal life support.

    Dr. Smith is involved in the Extracorporeal Life Support Program at Seattle Children’s Hospital and serves on the Steering Committee, which focuses on improving techniques to maximally support newborn infants not responsive to conventional therapies.

  • Patient Testimonials

  • Publications

    Manuscripts in Refereed Journals

    • Smith KM, McMullan DM, Bratton SL, Rycus P, Kinssela JP, Brogan TV
      Is age at initiation of extracorporeal life support associated with mortality and intraventricular hemorrhage in neonates with respiratory failure?
      J Perinatol, 2014 : 34(5)386-391

    Other Publications

    • McMullan DM, Thiagarajan RR, Smith KM, Rycus PT, Brogan TV
      Extracorporeal cardiopulmonary resuscitation outcomes in term and premature neonates*.
      24141660 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2014 Jan. : 15(1)e9-e16
    • Smith, KM
      Extracorporeal life support in neonates
      Neonatology, 7th edition, 2013
  • Presentations

    Presentation Title Event Location Date
    Use of the IPad for direct MCP consultation on transport HIMSS and Seattle Children's Mobile Health Tech Talk Seattle, WA Mar 26, 2014
    Volume Guarantee: Facts, Strategies and Case Studies in Neonatal Ventilation CCANN Conference "New Horizons in Neonatal Pulmonary Care Childrens Hospital of Central California, Madera, CA Apr 27, 2013
    Lines, Loops and Lessons Learned, Ventilating the Critically Ill Newborn Annual Dr. Enok Lohne Memorial Current Concepts and Innovations in Respiratory Care Madera, CA Apr 26, 2013
    Lines, Loops and Lessons Learned Alta Bates Hospital Oakland, CA Feb 21, 2012
  • Research Funding

    Grant Title Grantor Amount Award Date
    Partial liquid ventilation for lung protection in congenital diaphragmatic hernia (CDH) patients on ECLS Seattle Childrens Hospital -Academic Enrichment Fund $50,000
    A multi-center, randomized, placebo-controlled, double-blind, two-armed, parallel group study to evaluate efficacy and safety of IV Sildenafil in the treatment of neonates with persistent pulmonary hypertension of the newborn or hypoxic respiratory f Pfizer Pharmaceutical Company $51,827


Board Certification(s)

Neonatal-Perinatal Medicine

Medical/Professional School

University of Minnesota Medical School, Minneapolis, MN


University of Minnesota at Minneapolis, Minneapolis, MN


University of Minnesota at Minneapolis, Minneapolis, MN

Clinical Interests

Dr. Smith's clinical focus is on lung injury prevention in preterm and term neonates. She has studied ventilator techniques and different ventilation support modalities and works clinically on strategies to minimize lung trauma in infants requiring ventilation due to respiratory failure in the neonatal period.  Because of these interests, she serves as the Manager of Divisional Respiratory Care Programs with the goal of promoting improved ventilation strategies for neonates requiring ventilatory support in our region.