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Kasey Joanne Leger, MD, MSc

Kasey Joanne Leger, MD, MSc

Specialties

"It's an honor to partner with my patients and their families in their life changing battle against cancer. I am inspired to help my patients and those who will face this disease in the future to not only overcome cancer, but to experience healthy and fulfilling lives after cancer."
  • Biography

    Kasey Leger, MD, is the Medical Director of the Leukemia & Lymphoma program at Seattle Childrens Hospital and Associate Professor of Pediatrics at the University of Washington School of Medicine. Her clinical interests focus on management of leukemia, lymphoma, and cardiovascular health during cancer therapy.

    Dr. Leger's research focuses on maintaining the cardiovascular health of childhood cancer patients and survivors. Dr. Leger studies strategies to mitigate the cardiotoxicity of cancer therapy including primary cardioprotection (i.e. preventing cardiac damage from happening in the first place), as well as secondary cardioprotection, wherein cardiac directed medications may help prevent progressive heart damage in patients who have evidence of cardiotoxicity by sensitive cardiac testing. She leads the Children’s Oncology Group (COG) Myeloid Cardiotoxicity Working Group and serves as the cardiac chair of the ongoing COG Phase III randomized trial for patients with de novo AML comparing standard therapy to CPX-351 (AAML1831). This large, multi-institutional trial is assessing strategies to mitigate cardiotoxicity and leveraging a large, high-risk cohort to capture detailed cardiac phenotyping by echocardiographic measures of cardiac function and mechanics and circulating biomarkers of cardiac injury and stress. 

    Board Certification(s)

    Pediatrics
    Pediatric Hematology-Oncology

    Clinical Interests

    Leukemia, lymphoma and cardiovascular health during and following cancer therapy

    Research Description

    Early identification and prevention of cancer therapy-induced cardiovascular disease

    Research Focus Area

    Cancer biology

  • Related Resources

    • Kasey Joanne Leger, MD, MSc

      View the Seattle Children's Research Institute profile of Kasey Joanne Leger, MD, MSc including their publications and grants.

  • Patient Testimonials

  • Awards and Honors

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  • Publications

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  • Presentations

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  • Clinical Trials and Research Studies

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