Douglas S Hawkins, MD

Cancer and Blood Disorders Center, Thyroid Program, Bone Tumors and Soft Tissue Tumors, Solid Tumors Oncology

On staff since February 1996

Children's Title: Chair, Children's Oncology Group

Academic Title: Professor, Hematology-Oncology

Research Center: Ben Towne Center for Childhood Cancer Research

"I feel exceptionally fortunate to work with some of the smartest people I know. Each day brings new opportunities to learn from my colleagues, patients and families. By the nature of our work in Hematology/Oncology, we see the importance of what we do every day. I am continually impressed by our ability to change the lives of children and young adults for the better, both with good clinical care and by clinical and translational research efforts. My hope is that the clinical research done by the Children's Oncology Group and at Seattle Children's Hospital today will lead to more effective treatments with fewer side effects for children and young adults in the future."

Douglas S. Hawkins, MD, is the Group Chair of the Children's Oncology Group (COG). COG is the world’s largest organization devoted exclusively to childhood and adolescent cancer research. COG unites over 10,000 experts in childhood cancer at more than 200 leading children’s hospitals, universities, and cancer centers across North America, Australia, and New Zealand in the fight against childhood cancer. Dr. Hawkins is a clinician at Seattle Children's Hospital and Professor of Pediatrics at the University of Washington School of Medicine.

Dr. Hawkins is Group Chair of the Children's Oncology Group (COG). Prior to becoming COG Group Chair in 2020, he was the Chair of the COG Soft Tissue Sarcoma Committee, overseeing the conduct of biology studies and clinical trials for rhabdomyosarcoma and other soft tissue sarcomas across North America. Dr. Hawkins was a member of the COG Bone Tumor Steering Committee. His academic career has focused on clinical research, particularly in the treatment of pediatric sarcomas. He was the chair of two COG clinical trials, one for Ewing sarcoma and another for rhabdomyosarcoma. He chairs the international EURO EWING Consortium External Advisory Board, and also chairs the international Frontline and Relapse in RhabdoMyoSarcoma Study (FaR-RMS) Data Monitoring Committee.
- Kelly Seattle, WA 07.09.13
  
  Our sons life was saved by Dr. Hawkins and his incredible team. From the confusion and shock of the initial diagnosis to end of treatment celebration, Dr. Hawkins not only walked by our son's side every step of the way, he personally invested in our entire family. Dr. Hawkins is equal parts honest, courageous, brilliant, and compassionate. Dr. Hawkins and his team are an inspiration, and our family is eternally grateful for all that they do!
- Rahil Kent, WA 10.19.12
  
  Dr. Hawkins is a professional, kind and caring doctor with a large expertise in treating childhood cancer. Upon our orientation at Children's, he was the key person that explained the medicines, treatment plan, schedule and expectations. He explained differences in treatment plans in Europe and North America. He presented our scans, biopsy and test results making sure that we understood everything. He has done a good job and our son is now cured of cancer. Thank you Dr. Hawkins and the expert staff at Seattle Children's!
- Heather Snoqualmie, WA 09.25.12
  
  Dr. Hawkins and his incredible team saved out daughters life. Dr. Hawkins had the insight to look past the original diagnosis given to our daughter. She was diagnosed with TEC at 15 months with a HCT of 7. This was not life sustaining. He and his team consulted, worked, planned and communitcated with each other and our family to come up with the best course of treatment. I cant thank Dr. Hawkins and Seattle Children's enough. They preform miracles everyday!
- janice wenatchee, wa. 02.13.12
  
  Dr. Hawkins works around the clock to give our children the best care. I am happy to say my son is a bone cancer survivor. I appreciated how Dr. Hawkins worked to make sure the side affects from the chemo where addressed as well as its progress. Thank you so much, Janice B.
- elce kent,washinton 09.28.11
  
  Dr. Hawkins saved my daughters life,who was diagnosed with stage 4 alveolar rhabdomyosarcoma last year.My daughter is cancer free for almost three months now because of Dr. Hawkins and his team.God bless them.God is Good.
- Becky seattle ,wa 06.16.11
  
  I was a distraught parent when my daughter was diagnosed at 15 with Hodgkin's lymphoma. he spent the time to make me feel at ease and encouraged me to participate in her care . i didn't have a clue what i should do . he made me feel comfortable to ask a lot of questions, and he answered with reassurance and calmness . He worked closely with me as a parent as well as his colleagues to give her the best care she could get. he responded as quickly as possible to all of my phone calls. He is a very humble man for all of his qualifications . there are a lot of people who look up to him , if he only knew how many .... many thanks!! we pray for his continued success!!
- Lynora Ketchikan, Alaska 04.14.11
  
  Five years ago, my 8 1/2 year old son was diagnosed with Hodgkin's Lymphoma. I remember Dr Hawkins looking me right in the eye and saying, "This cancer is very, very, VERY curable." I clung to his words, and today we are celebrating my son's 14th birthday. Thank you Dr. Hawkins, and Children's, for assisting God in our son's healing!
- Lynora Ketchikan, Alaska 04.14.11
  
  Five years ago, my 8 1/2 year old son was diagnosed with Hodgkin's Lymphoma. I remember Dr Hawkins looking me right in the eye and saying, "This cancer is very, very, VERY curable." I clung to his words, and today we are celebrating my son's 14th birthday. Thank you Dr. Hawkins, and Children's, for assisting God in our son's healing!
- Kathleen Seattle, WA 03.30.11
  
  If you are seeing Dr. Hawkins, you've likely heard the worst thing you will ever hear: your child has cancer. If that's the case, thank God you're seeing Dr. Hawkins! My son nearly died before he was diagnosed in 1997 at age 2 with Burkitt's Lymphoma. We were so grateful to have Dr. Hawkins on his team. He's honest, clear, compassionate and simply the most knowledgeable physician treating kids today. My son is 16 now, rowing crew and making the honor roll!
- camille seattle washington 02.17.11
  
  Dr. Hawkins is my personal Hero! I was two weeks short of dying when he took over. I had stage 4 hodgkins lymphoma I was 15 yrs old. I am now 20 and I have a beautiful son and have been in remisson for 5 yrs now. Thank you Dr. Hawkins!
- Tammy Maple Valley, WA 12.10.10
  
  Dr. Doug Hawkins and Dr. Lawrence Cooper diagnosed our son Eric as a Lg Cell Lymphoma patient in early 1997 when he was 10. Eric recently had his 24th Birthday, THANKS TO THEIR KNOWLEDGE AND CARE. He is a SURVIVOR!! Thank you to them and all the wonderful nurses that made that hard time bearable. Sincerely, Eric's Mom & Dad
Recommend Douglas S Hawkins, MD

Award Name	Awarded By	Award Date
SEATTLE TOP DOCTOR - 2012 to 2022	Seattle Magazine	2022
Seattle's Top Doctor 2020	Seattle Met	2020
Seattle's Top Doctor 2016	Seattle Met Magazine	2016
Seattle's Top Doctor 2013	Seattle Met Magazine	2013
U.S. News Top Doctor	U.S. News and World Report	2012
Newsweek Health: Top Cancer Doctors 2015	Newsweek	2015

Other Publications

Eckstein OS, Allen CE, Williams PM, Roy-Chowdhuri S, Patton DR, Coffey B, Reid JM, Piao J, Saguilig L, Alonzo TA, Berg SL, Ramirez NC, Jaju A, Mhlanga J, Fox E, Hawkins DS, Mooney MM, Takebe N, Tricoli JV, Janeway KA, Seibel NL, Parsons DW
Phase II Study of Selumetinib in Children and Young Adults With Tumors Harboring Activating Mitogen-Activated Protein Kinase Pathway Genetic Alterations: Arm E of the NCI-COG Pediatric MATCH Trial.
35363510 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022 April 1 : JCO2102840

Haduong JH, Heske CM, Allen-Rhoades W, Xue W, Teot LA, Rodeberg DA, Donaldson SS, Weiss A, Hawkins DS, Venkatramani R
An update on rhabdomyosarcoma risk stratification and the rationale for current and future Children's Oncology Group clinical trials.
35129294 Pediatric blood & cancer, 2022 April : 69(4)e29511 PMCID:PMC8976559

Parsons DW, Janeway KA, Patton DR, Winter CL, Coffey B, Williams PM, Roy-Chowdhuri S, Tsongalis GJ, Routbort M, Ramirez NC, Saguilig L, Piao J, Alonzo TA, Berg SL, Fox E, Hawkins DS, Abrams JS, Mooney M, Takebe N, Tricoli JV, Seibel NL, NCI-COG Pediatric MATCH Team.
Actionable Tumor Alterations and Treatment Protocol Enrollment of Pediatric and Young Adult Patients With Refractory Cancers in the National Cancer Institute-Children's Oncology Group Pediatric MATCH Trial.
35353553 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022 March 30 : JCO2102838

Crane JN, Xue W, Qumseya A, Gao Z, Arndt CAS, Donaldson SS, Harrison DJ, Hawkins DS, Linardic CM, Mascarenhas L, Meyer WH, Rodeberg DA, Rudzinski ER, Shulkin BL, Walterhouse DO, Venkatramani R, Weiss AR
Clinical group and modified TNM stage for rhabdomyosarcoma: A review from the Children's Oncology Group.
35253352 Pediatric blood & cancer, 2022 March 6 : e29644

Fetzko S, Fonseca A, Frances Wedekind M, Gupta AA, Setty BA, Schraw J, Lupo PJ, Guillerman RP, Butala AA, Russell H, Nicholls L, Walterhouse D, Hawkins DS, Okcu MF
Is Detection of Relapse by Surveillance Imaging Associated With Longer Survival in Patients With Rhabdomyosarcoma?
35137727 Journal of pediatric hematology/oncology, 2022 Feb. 9

Russell HV, Chi YY, Okcu MF, Bernhardt MB, Rodriguez-Galindo C, Gupta AA, Hawkins DS
Rising drug cost impacts on cost-effectiveness of 2 chemotherapy regimens for intermediate-risk rhabdomyosarcoma: A report from the Children's Oncology Group.
34623638 Cancer, 2022 Jan. 15 : 128(2)317-325 PMCID:PMC8738099

Pearson AD, Rossig C, Mackall C, Shah NN, Baruchel A, Reaman G, Ricafort R, Heenen D, Bassan A, Berntgen M, Bird N, Bleickardt E, Bouchkouj N, Bross P, Brownstein C, Cohen SB, de Rojas T, Ehrlich L, Fox E, Gottschalk S, Hanssens L, Hawkins DS, Horak ID, Taylor DH, Johnson C, Karres D, Ligas F, Ludwinski D, Mamonkin M, Marshall L, Masouleh BK, Matloub Y, Maude S, McDonough J, Minard-Colin V, Norga K, Nysom K, Pappo A, Pearce L, Pieters R, Pule M, Quintás-Cardama A, Richardson N, Schüßler-Lenz M, Scobie N, Sersch MA, Smith MA, Sterba J, Tasian SK, Weigel B, Weiner SL, Zwaan CM, Lesa G, Vassal G
Paediatric Strategy Forum for medicinal product development of chimeric antigen receptor T-cells in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
34840026 European journal of cancer (Oxford, England : 1990), 2022 Jan. : 160112-133

Leavey PJ, Laack NN, Krailo MD, Buxton A, Randall RL, DuBois SG, Reed DR, Grier HE, Hawkins DS, Pawel B, Nadel H, Womer RB, Letson GD, Bernstein M, Brown K, Maciej A, Chuba P, Ahmed AA, Indelicato DJ, Wang D, Marina N, Gorlick R, Janeway KA, Mascarenhas L
Phase III Trial Adding Vincristine-Topotecan-Cyclophosphamide to the Initial Treatment of Patients With Nonmetastatic Ewing Sarcoma: A Children's Oncology Group Report.
34652968 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021 Dec. 20 : 39(36)4029-4038 PMCID:PMC8677904

Collier AB 3rd, Krailo MD, Dang HM, DuBois SG, Hawkins DS, Bernstein ML, Bomgaars LR, Reed DR, Gorlick RG, Janeway KA
Outcome of patients with relapsed or progressive Ewing sarcoma enrolled on cooperative group phase 2 clinical trials: A report from the Children's Oncology Group.
34496122 Pediatric blood & cancer, 2021 Dec. : 68(12)e29333 PMCID:PMC8541905

Pinto N, Navarro SL, Rimorin C, Wurscher M, Hawkins DS, McCune JS
Pharmacogenomic associations of cyclophosphamide pharmacokinetic candidate genes with event-free survival in intermediate-risk rhabdomyosarcoma: A report from the Children's Oncology Group.
34245211 Pediatric blood & cancer, 2021 Nov. : 68(11)e29203 PMCID:PMC8719493

Brady C, Manning SC, Rudzinski E, Paulson V, Wang X, Liu YJ, Parikh SR, Bonilla-Velez J, Hawkins DS, Dahl J
Clinical Outcomes of Diffuse Sclerosing Variant Papillary Thyroid Carcinoma in Pediatric Patients.
34713899 The Laryngoscope, 2021 Oct. 29

Shern JF, Selfe J, Izquierdo E, Patidar R, Chou HC, Song YK, Yohe ME, Sindiri S, Wei J, Wen X, Rudzinski ER, Barkauskas DA, Lo T, Hall D, Linardic CM, Hughes D, Jamal S, Jenney M, Chisholm J, Brown R, Jones K, Hicks B, Angelini P, George S, Chesler L, Hubank M, Kelsey A, Gatz SA, Skapek SX, Hawkins DS, Shipley JM, Khan J
Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium.
34166060 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021 Sept. 10 : 39(26)2859-2871 PMCID:PMC8425837

Avutu V, Weiss AR, Reed DR, Ahmed SK, Allen-Rhoades WA, Chen YE, Davis LE, Eaton BR, Hawkins DS, Indelicato DJ, Patel SR, Randall RL, Reinke DK, Riedel RF, Scharschmidt TJ, Thornton KA, Wang D, Janeway KA, Kopp LM
Identified Enrollment Challenges of Adolescent and Young Adult Patients on the Nonchemotherapy Arm of Children's Oncology Group Study ARST1321.
34515544 Journal of adolescent and young adult oncology, 2021 Sept. 9

Million L, Hayes-Jordan A, Chi YY, Donaldson SS, Wolden S, Morris C, Terezakis S, Laurie F, Morano K, Fitzgerald TJ, Yock TI, Rodeberg DA, Anderson JR, Speights RA, Black JO, Coffin C, McCarville MB, Kao SC, Hawkins DS, Spunt SL, Randall RL
Local Control For High-Grade Nonrhabdomyosarcoma Soft Tissue Sarcoma Assigned to Radiation Therapy on ARST0332: A Report From the Childrens Oncology Group.
33548339 International journal of radiation oncology, biology, physics, 2021 July 1 : 110(3)821-830 PMCID:PMC8767764

Li H, Sisoudiya SD, Martin-Giacalone BA, Khayat MM, Dugan-Perez S, Marquez-Do DA, Scheurer ME, Muzny D, Boerwinkle E, Gibbs RA, Chi YY, Barkauskas DA, Lo T, Hall D, Stewart DR, Schiffman JD, Skapek SX, Hawkins DS, Plon SE, Sabo A, Lupo PJ
Germline Cancer Predisposition Variants in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group.
33372952 Journal of the National Cancer Institute, 2021 July 1 : 113(7)875-883 PMCID:PMC8246828

Kohli K, Yao L, Nowicki TS, Zhang S, Black RG, Schroeder BA, Farrar EA, Cao J, Sloan H, Stief D, Cranmer LD, Wagner MJ, Hawkins DS, Pillarisetty VG, Ribas A, Campbell J, Pierce RH, Kim EY, Jones RL, Riddell SR, Yee C, Pollack SM
IL-15 mediated expansion of rare durable memory T cells following adoptive cellular therapy.
33963013 Journal for immunotherapy of cancer, 2021 May : 9(5) PMCID:PMC8108691

Chugh R, Ballman KV, Helman LJ, Patel S, Whelan JS, Widemann B, Lu Y, Hawkins DS, Mascarenhas L, Glod JW, Ji J, Zhang Y, Reinke D, Strauss SJ
SARC025 arms 1 and 2: A phase 1 study of the poly(ADP-ribose) polymerase inhibitor niraparib with temozolomide or irinotecan in patients with advanced Ewing sarcoma.
33289920 Cancer, 2021 April 15 : 127(8)1301-1310 PMCID:PMC8246769

Pacenta HL, Allen-Rhoades W, Langenau D, Houghton PJ, Keller C, Heske CM, Deel MD, Linardic CM, Shern JF, Stewart E, Turpin B, Harrison DJ, Khan J, Mascarenhas L, Skapek SX, Meyer WH, Hawkins DS, Chen EY, Amatruda JF, Hingorani P, Laetsch TW
Prioritization of Novel Agents for Patients with Rhabdomyosarcoma: A Report from the Children's Oncology Group (COG) New Agents for Rhabdomyosarcoma Task Force.
33915882 Journal of clinical medicine, 2021 April 1 : 10(7) PMCID:PMC8037615

Rogers TN, Seitz G, Fuchs J, Martelli H, Dasgupta R, Routh JC, Hawkins DS, Koscielniak E, Bisogno G, Rodeberg DA
Surgical management of paratesticular rhabdomyosarcoma: A consensus opinion from the Children's Oncology Group, European paediatric Soft tissue sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe.
33522706 Pediatric blood & cancer, 2021 April : 68(4)e28938

Heske CM, Chi YY, Venkatramani R, Li M, Arnold MA, Dasgupta R, Hiniker SM, Hawkins DS, Mascarenhas L
Survival outcomes of patients with localized FOXO1 fusion-positive rhabdomyosarcoma treated on recent clinical trials: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.
33216382 Cancer, 2021 March 15 : 127(6)946-956 PMCID:PMC8601034

Gallego S, Chi YY, De Salvo GL, Li M, Merks JHM, Rodeberg DA, van Scheltinga ST, Mascarenhas L, Orbach D, Jenney M, Million L, Minard-Colin V, Wolden S, Zanetti I, Parham DM, Mandeville H, Venkatramani R, Bisogno G, Hawkins DS, European paediatric Soft tissue sarcoma Study Group and Children's Oncology Group.
Alveolar rhabdomyosarcoma with regional nodal involvement: Results of a combined analysis from two cooperative groups.
33245207 Pediatric blood & cancer, 2021 March : 68(3)e28832 PMCID:PMC8414760

Moreira DC, Millen GC, Sands S, Kearns PR, Hawkins DS
The Care of Children With Cancer During the COVID-19 Pandemic.
33989020 American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 2021 March : 411-10

Rudzinski ER, Kelsey A, Vokuhl C, Linardic CM, Shipley J, Hettmer S, Koscielniak E, Hawkins DS, Bisogno G
Pathology of childhood rhabdomyosarcoma: A consensus opinion document from the Children's Oncology Group, European Paediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe.
33306276 Pediatric blood & cancer, 2021 March : 68(3)e28798

Harrison DJ, Chi YY, Tian J, Hingorani P, Mascarenhas L, McCowage GB, Weigel BJ, Venkatramani R, Wolden SL, Yock TI, Rodeberg DA, Hayes-Jordan AA, Teot LA, Spunt SL, Meyer WH, Hawkins DS, Shulkin BL, Parisi MT
Metabolic response as assessed by 18 F-fluorodeoxyglucose positron emission tomography-computed tomography does not predict outcome in patients with intermediate- or high-risk rhabdomyosarcoma: A report from the Children's Oncology Group Soft Tissue Sarcoma Committee.
33340280 Cancer medicine, 2021 Feb. : 10(3)857-866 PMCID:PMC7897958

Lautz TB, Chi YY, Li M, Wolden SL, Casey DL, Routh JC, Granberg CF, Binite O, Rudzinski ER, Hawkins DS, Venkatramani R, Rodeberg DA
Benefit of delayed primary excision in rhabdomyosarcoma: A report from the Children's Oncology Group.
33079399 Cancer, 2021 Jan. 15 : 127(2)275-283 PMCID:PMC7790947

Kim J, Light N, Subasri V, Young EL, Wegman-Ostrosky T, Barkauskas DA, Hall D, Lupo PJ, Patidar R, Maese LD, Jones K, Wang M, Tavtigian SV, Wu D, Shlien A, Telfer F, Goldenberg A, Skapek SX, Wei JS, Wen X, Catchpoole D, Hawkins DS, Schiffman JD, Khan J, Malkin D, Stewart DR
Pathogenic Germline Variants in Cancer Susceptibility Genes in Children and Young Adults With Rhabdomyosarcoma.
34095712 JCO precision oncology, 2021 : 5 PMCID:PMC8169077

Shenoy A, Alvarez E, Chi YY, Li M, Shern JF, Khan J, Hiniker SM, Granberg CF, Hawkins DS, Parham DM, Teot LA, Rudzinski ER
The prognostic significance of anaplasia in childhood rhabdomyosarcoma: A report from the Children's Oncology Group.
33302115 European journal of cancer (Oxford, England : 1990), 2021 Jan. : 143127-133 PMCID:PMC8842073

Bertagnolli MM, Blanke CD, Curran WJ, Hawkins DS, Mannel RS, O'Dwyer PJ, Schnall MD, Wolmark N
What happened to the US cancer cooperative groups? A status update ten years after the Institute of Medicine report.
32970346 Cancer, 2020 Dec. 1 : 126(23)5022-5029 PMCID:PMC7667615

Hawkins DS, Bisogno G, Koscielniak E
Introducing INSTRuCT: An international effort to promote cooperation and data sharing.
32918788 Pediatric blood & cancer, 2020 Sept. 12 : e28701

Orbach D, Sparber-Sauer M, Laetsch TW, Minard-Colin V, Bielack SS, Casanova M, Corradini N, Koscielniak E, Scheer M, Hettmer S, Bisogno G, Hawkins DS, Ferrari A
Spotlight on the treatment of infantile fibrosarcoma in the era of neurotrophic tropomyosin receptor kinase inhibitors: International consensus and remaining controversies.
32784118 European journal of cancer (Oxford, England : 1990), 2020 Aug. 9 : 137183-192

Morris CD, Tunn PU, Rodeberg DA, Terwisscha van Scheltinga S, Binitie O, Godzinski J, Dall'Igna P, Million L, Hawkins DS, Koscielniak E, Bisogno G, Rogers TN
Surgical management of extremity rhabdomyosarcoma: A consensus opinion from the Children's Oncology Group, the European Pediatric Soft-Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe.
32776456 Pediatric blood & cancer, 2020 Aug. 9 : e28608

Lautz TB, Martelli H, Fuchs J, Chargari C, Smeulders N, Granberg CF, Wolden SL, Sparber-Sauer M, Hawkins DS, Bisogno G, Koscielniak E, Rodeberg DA, Seitz G, INSTRuCT group.
Local treatment of rhabdomyosarcoma of the female genital tract: Expert consensus from the Children's Oncology Group, the European Soft-Tissue Sarcoma Group, and the Cooperative Weichteilsarkom Studiengruppe.
32762004 Pediatric blood & cancer, 2020 Aug. 6 : e28601

Weiss AR, Chen YL, Scharschmidt TJ, Chi YY, Tian J, Black JO, Davis JL, Fanburg-Smith JC, Zambrano E, Anderson J, Arens R, Binitie O, Choy E, Davis JW, Hayes-Jordan A, Kao SC, Kayton ML, Kessel S, Lim R, Meyer WH, Million L, Okuno SH, Ostrenga A, Parisi MT, Pryma DA, Randall RL, Rosen MA, Schlapkohl M, Shulkin BL, Smith EA, Sorger JI, Terezakis S, Hawkins DS, Spunt SL, Wang D
Pathological response in children and adults with large unresected intermediate-grade or high-grade soft tissue sarcoma receiving preoperative chemoradiotherapy with or without pazopanib (ARST1321): a multicentre, randomised, open-label, phase 2 trial.
32702309 The Lancet. Oncology, 2020 Aug. : 21(8)1110-1122

Hingorani P, Dinu V, Zhang X, Lei H, Shern JF, Park J, Steel J, Rauf F, Parham D, Gastier-Foster J, Hall D, Hawkins DS, Skapek SX, Labaer J, McEachron TA
Transcriptome analysis of desmoplastic small round cell tumors identifies actionable therapeutic targets: a report from the Children's Oncology Group.
32703985 Scientific reports, 2020 July 23 : 10(1)12318 PMCID:PMC7378211

Schultz L, Link MP, Rheingold S, Hawkins DS, Dome JS, Wickiser J, Kung AL, Henderson TO, Aftandilian C
Summary of COVID-19 clinical practice adjustments across select institutions.
32779834 Pediatric blood & cancer, 2020 July 19 : e28411

Kazahaya K, Prickett KK, Paulson VA, Dahl JP, Manning SC, Rudzinski ER, Rastatter JC, Parikh SR, Hawkins DS, Brose MS, Bauer AJ
Targeted Oncogene Therapy Before Surgery in Pediatric Patients With Advanced Invasive Thyroid Cancer at Initial Presentation: Is It Time for a Paradigm Shift?
32614439 JAMA otolaryngology-- head & neck surgery, 2020 July 2

Sullivan M, Bouffet E, Rodriguez-Galindo C, Luna-Fineman S, Khan MS, Kearns P, Hawkins DS, Challinor J, Morrissey L, Fuchs J, Marcus K, Balduzzi A, Basset-Salom L, Caniza M, Baker JN, Kebudi R, Hessissen L, Sullivan R, Pritchard-Jones K
The COVID-19 pandemic: A rapid global response for children with cancer from SIOP, COG, SIOP-E, SIOP-PODC, IPSO, PROS, CCI, and St Jude Global.
32400924 Pediatric blood & cancer, 2020 July : 67(7)e28409 PMCID:PMC7235469

Routh JC, Dasgupta R, Chi YY, Shnorhavorian M, Tian J, Walterhouse DO, Breneman J, Wolden SL, Arndt CA, Hawkins DS, Rodeberg DA
Impact of Local Control and Surgical Lymph Node Evaluation in Localized Paratesticular Rhabdomyosarcoma: A Report from the Children's Oncology Group Soft Tissue Sarcoma Committee.
32525556 International journal of cancer, 2020 June 11

Prasad PK, Mahajan P, Hawkins DS, Mostoufi-Moab S, Venkatramani R
Management of pediatric differentiated thyroid cancer: An overview for the pediatric oncologist.
32275118 Pediatric blood & cancer, 2020 June : 67(6)e28141

Bisogno G, Hawkins DS
An unresolved issue in rhabdomyosarcoma treatment: The duration of chemotherapy.
31994316 Pediatric blood & cancer, 2020 May : 67(5)e28174

Aye JM, Chi YY, Tian J, Rudzinski ER, Binitie OT, Dasgupta R, Wolden SL, Hawkins DS, Gupta AA
Do children and adolescents with completely resected alveolar rhabdomyosarcoma require adjuvant radiation? A report from the Children's Oncology Group.
32124549 Pediatric blood & cancer, 2020 May : 67(5)e28243

Lautz TB, Chi YY, Tian J, Gupta AA, Wolden SL, Routh JC, Casey DL, Dasgupta R, Hawkins DS, Rodeberg DA
Relationship between tumor response at therapy completion and prognosis in patients with Group III rhabdomyosarcoma: A report from the Children's Oncology Group.
32012255 International journal of cancer, 2020 Feb. 3

Spunt SL, Million L, Chi YY, Anderson J, Tian J, Hibbitts E, Coffin C, McCarville MB, Randall RL, Parham DM, Black JO, Kao SC, Hayes-Jordan A, Wolden S, Laurie F, Speights R, Kawashima E, Skapek SX, Meyer W, Pappo AS, Hawkins DS
A risk-based treatment strategy for non-rhabdomyosarcoma soft-tissue sarcomas in patients younger than 30 years (ARST0332): a Children's Oncology Group prospective study.
31786124 The Lancet. Oncology, 2020 Jan. : 21(1)145-161 PMCID:PMC6946838

Dirksen U, Brennan B, Le Deley MC, Cozic N, van den Berg H, Bhadri V, Brichard B, Claude L, Craft A, Amler S, Gaspar N, Gelderblom H, Goldsby R, Gorlick R, Grier HE, Guinbretiere JM, Hauser P, Hjorth L, Janeway K, Juergens H, Judson I, Krailo M, Kruseova J, Kuehne T, Ladenstein R, Lervat C, Lessnick SL, Lewis I, Linassier C, Marec-Berard P, Marina N, Morland B, Pacquement H, Paulussen M, Randall RL, Ranft A, Le Teuff G, Wheatley K, Whelan J, Womer R, Oberlin O, Hawkins DS, Euro-E.W.I.N.G. 99 and Ewing 2008 Investigators.
High-Dose Chemotherapy Compared With Standard Chemotherapy and Lung Radiation in Ewing Sarcoma With Pulmonary Metastases: Results of the European Ewing Tumour Working Initiative of National Groups, 99 Trial and EWING 2008.
31553693 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019 Dec. 1 : 37(34)3192-3202 PMCID:PMC6881099

Mascarenhas L, Chi YY, Hingorani P, Anderson JR, Lyden ER, Rodeberg DA, Indelicato DJ, Kao SC, Dasgupta R, Spunt SL, Meyer WH, Hawkins DS
Randomized Phase II Trial of Bevacizumab or Temsirolimus in Combination With Chemotherapy for First Relapse Rhabdomyosarcoma: A Report From the Children's Oncology Group.
31513481 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019 Nov. 1 : 37(31)2866-2874 PMCID:PMC6823886

Yohe ME, Heske CM, Stewart E, Adamson PC, Ahmed N, Antonescu CR, Chen E, Collins N, Ehrlich A, Galindo RL, Gryder BE, Hahn H, Hammond S, Hatley ME, Hawkins DS, Hayes MN, Hayes-Jordan A, Helman LJ, Hettmer S, Ignatius MS, Keller C, Khan J, Kirsch DG, Linardic CM, Lupo PJ, Rota R, Shern JF, Shipley J, Sindiri S, Tapscott SJ, Vakoc CR, Wexler LH, Langenau DM
Insights into pediatric rhabdomyosarcoma research: Challenges and goals.
31222885 Pediatric blood & cancer, 2019 Oct. : 66(10)e27869 PMCID:PMC6707829

Hibbitts E, Chi YY, Hawkins DS, Barr FG, Bradley JA, Dasgupta R, Meyer WH, Rodeberg DA, Rudzinski ER, Spunt SL, Skapek SX, Wolden SL, Arndt CAS
Refinement of risk stratification for childhood rhabdomyosarcoma using FOXO1 fusion status in addition to established clinical outcome predictors: A report from the Children's Oncology Group.
31456361 Cancer medicine, 2019 Oct. : 8(14)6437-6448 PMCID:PMC6797586

Paulson VA, Rudzinski ER, Hawkins DS
Thyroid Cancer in the Pediatric Population.
31540418 Genes, 2019 Sept. 18 : 10(9) PMCID:PMC6771006

Casey DL, Chi YY, Donaldson SS, Hawkins DS, Tian J, Arndt CA, Rodeberg DA, Routh JC, Lautz TB, Gupta AA, Yock TI, Wolden SL
Increased local failure for patients with intermediate-risk rhabdomyosarcoma on ARST0531: A report from the Children's Oncology Group.
31174239 Cancer, 2019 Sept. 15 : 125(18)3242-3248 PMCID:PMC6717036

Mascarenhas L, Lyden ER, Breitfeld PP, Walterhouse DO, Donaldson SS, Rodeberg DA, Parham DM, Anderson JR, Meyer WH, Hawkins DS
Risk-based treatment for patients with first relapse or progression of rhabdomyosarcoma: A report from the Children's Oncology Group.
31067356 Cancer, 2019 Aug. 1 : 125(15)2602-2609 PMCID:PMC7069123

Bharathy N, Berlow NE, Wang E, Abraham J, Settelmeyer TP, Hooper JE, Svalina MN, Bajwa Z, Goros MW, Hernandez BS, Wolff JE, Pal R, Davies AM, Ashok A, Bushby D, Mancini M, Noakes C, Goodwin NC, Ordentlich P, Keck J, Hawkins DS, Rudzinski ER, Mansoor A, Perkins TJ, Vakoc CR, Michalek JE, Keller C
Preclinical rationale for entinostat in embryonal rhabdomyosarcoma.
31113472 Skeletal muscle, 2019 May 21 : 9(1)12 PMCID:PMC6528217

Spunt SL, Francotte N, De Salvo GL, Chi YY, Zanetti I, Hayes-Jordan A, Kao SC, Orbach D, Brennan B, Weiss AR, van Noesel MM, Million L, Alaggio R, Parham DM, Kelsey A, Randall RL, McCarville MB, Bisogno G, Hawkins DS, Ferrari A
Clinical features and outcomes of young patients with epithelioid sarcoma: an analysis from the Children's Oncology Group and the European paediatric soft tissue Sarcoma Study Group prospective clinical trials.
30954717 European journal of cancer (Oxford, England : 1990), 2019 May : 11298-106 PMCID:PMC6944741

Lowery CD, Dowless M, Renschler M, Blosser W, VanWye AB, Stephens JR, Iversen PW, Lin AB, Beckmann RP, Krytska K, Cole KA, Maris JM, Hawkins DS, Rubin BP, Kurmasheva RT, Houghton PJ, Gorlick R, Kolb EA, Kang MH, Reynolds CP, Erickson SW, Teicher BA, Smith MA, Stancato LF
Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models.
30563935 Clinical cancer research : an official journal of the American Association for Cancer Research, 2019 April 1 : 25(7)2278-2289 PMCID:PMC6445779

Davis JL, Lockwood CM, Stohr B, Boecking C, Al-Ibraheemi A, DuBois SG, Vargas SO, Black JO, Cox MC, Luquette M, Turpin B, Szabo S, Laetsch TW, Albert CM, Parham DM, Hawkins DS, Rudzinski ER
Expanding the Spectrum of Pediatric NTRK-rearranged Mesenchymal Tumors.
30585824 The American journal of surgical pathology, 2019 April : 43(4)435-445

Smeland S, Bielack SS, Whelan J, Bernstein M, Hogendoorn P, Krailo MD, Gorlick R, Janeway KA, Ingleby FC, Anninga J, Antal I, Arndt C, Brown KLB, Butterfass-Bahloul T, Calaminus G, Capra M, Dhooge C, Eriksson M, Flanagan AM, Friedel G, Gebhardt MC, Gelderblom H, Goldsby R, Grier HE, Grimer R, Hawkins DS, Hecker-Nolting S, Sundby Hall K, Isakoff MS, Jovic G, KÃ¼hne T, Kager L, von Kalle T, Kabickova E, Lang S, Lau CC, Leavey PJ, Lessnick SL, Mascarenhas L, Mayer-Steinacker R, Meyers PA, Nagarajan R, Randall RL, Reichardt P, Renard M, Rechnitzer C, Schwartz CL, Strauss S, Teot L, Timmermann B, Sydes MR, Marina N
Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort.
30685685 European journal of cancer (Oxford, England : 1990), 2019 March : 10936-50 PMCID:PMC6506906

Malempati S, Weigel BJ, Chi YY, Tian J, Anderson JR, Parham DM, Teot LA, Rodeberg DA, Yock TI, Shulkin BL, Spunt SL, Meyer WH, Hawkins DS
The addition of cixutumumab or temozolomide to intensive multiagent chemotherapy is feasible but does not improve outcome for patients with metastatic rhabdomyosarcoma: A report from the Children's Oncology Group.
30351457 Cancer, 2019 Jan. 15 : 125(2)290-297 PMCID:PMC6329653

Skapek SX, Ferrari A, Gupta AA, Lupo PJ, Butler E, Shipley J, Barr FG, Hawkins DS
Rhabdomyosarcoma.
30617281 Nature reviews. Disease primers, 2019 Jan. 7 : 5(1)1

Laetsch TW, Hawkins DS
Larotrectinib for the treatment of TRK fusion solid tumors.
30350734 Expert review of anticancer therapy, 2019 Jan. : 19(1)1-10

Sayles LC, Breese MR, Koehne AL, Leung SG, Lee AG, Liu HY, Spillinger A, Shah AT, Tanasa B, Straessler K, Hazard FK, Spunt SL, Marina N, Kim GE, Cho SJ, Avedian RS, Mohler DG, Kim MO, DuBois SG, Hawkins DS, Sweet-Cordero EA
Genome-Informed Targeted Therapy for Osteosarcoma.
30266815 Cancer discovery, 2019 Jan. : 9(1)46-63 PMCID:PMC7134333

Bradley JA, Kayton ML, Chi YY, Hawkins DS, Tian J, Breneman J, Wolden SL, Walterhouse D, Rodeberg DA, Donaldson SS
Treatment Approach and Outcomes in Infants With Localized Rhabdomyosarcoma: A Report From the Soft Tissue Sarcoma Committee of the Children's Oncology Group.
30138647 International journal of radiation oncology, biology, physics, 2019 Jan. 1 : 103(1)19-27 PMCID:PMC6301106

Bharathy N, Berlow NE, Wang E, Abraham J, Settelmeyer TP, Hooper JE, Svalina MN, Ishikawa Y, Zientek K, Bajwa Z, Goros MW, Hernandez BS, Wolff JE, Rudek MA, Xu L, Anders NM, Pal R, Harrold AP, Davies AM, Ashok A, Bushby D, Mancini M, Noakes C, Goodwin NC, Ordentlich P, Keck J, Hawkins DS, Rudzinski ER, Chatterjee B, BÃ¤chinger HP, Barr FG, Liddle J, Garcia BA, Mansoor A, Perkins TJ, Vakoc CR, Michalek JE, Keller C
The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma.
30459282 Science signaling, 2018 Nov. 20 : 11(557) PMCID:PMC6432638

Walterhouse DO, Barkauskas DA, Hall D, Ferrari A, De Salvo GL, Koscielniak E, Stevens MCG, Martelli H, Seitz G, Rodeberg DA, Shnorhavorian M, Dasgupta R, Breneman JC, Anderson JR, Bergeron C, Bisogno G, Meyer WH, Hawkins DS, Minard-Colin V
Demographic and Treatment Variables Influencing Outcome for Localized Paratesticular Rhabdomyosarcoma: Results From a Pooled Analysis of North American and European Cooperative Groups.
30351998 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018 Oct. 23 : JCO2018789388 PMCID:PMC6286163

Hawkins DS, Chi YY, Anderson JR, Tian J, Arndt CAS, Bomgaars L, Donaldson SS, Hayes-Jordan A, Mascarenhas L, McCarville MB, McCune JS, McCowage G, Million L, Morris CD, Parham DM, Rodeberg DA, Rudzinski ER, Shnorhavorian M, Spunt SL, Skapek SX, Teot LA, Wolden S, Yock TI, Meyer WH
Addition of Vincristine and Irinotecan to Vincristine, Dactinomycin, and Cyclophosphamide Does Not Improve Outcome for Intermediate-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group.
30091945 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018 Sept. 20 : 36(27)2770-2777 PMCID:PMC6145831

Minard-Colin V, Walterhouse D, Bisogno G, Martelli H, Anderson J, Rodeberg DA, Ferrari A, Jenney M, Wolden S, De Salvo G, Arndt C, Merks JHM, Gallego S, Schwob D, Haie-Meder C, Bergeron C, Stevens MCG, Oberlin O, Hawkins D, International Society of Pediatric Oncology Sarcoma Committee, the Children's Oncology Group, the Italian Cooperative Soft Tissue Sarcoma Group, and the European pediatric Soft tissue sarcoma Study Group.
Localized vaginal/uterine rhabdomyosarcoma-results of a pooled analysis from four international cooperative groups.
29781567 Pediatric blood & cancer, 2018 Sept. : 65(9)e27096

Xu L, Zheng Y, Liu J, Rakheja D, Singleterry S, Laetsch TW, Shern JF, Khan J, Triche TJ, Hawkins DS, Amatruda JF, Skapek SX
Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes.
29972784 Cell reports, 2018 July 3 : 24(1)238-251 PMCID:PMC7293769

Teot LA, Schneider M, Thorner AR, Tian J, Chi YY, Ducar M, Lin L, Wlodarski M, Grier HE, Fletcher CDM, van Hummelen P, Skapek SX, Hawkins DS, Wagers AJ, Rodriguez-Galindo C, Hettmer S
Clinical and mutational spectrum of highly differentiated, paired box 3:forkhead box protein o1 fusion-negative rhabdomyosarcoma: A report from the Children's Oncology Group.
29461635 Cancer, 2018 May 1 : 124(9)1973-1981 PMCID:PMC5910184

Laetsch TW, Roy A, Xu L, Black JO, Coffin CM, Chi YY, Tian J, Spunt SL, Hawkins DS, Bridge JA, Parsons DW, Skapek SX
Undifferentiated sarcomas in children harbor clinically-relevant oncogenic fusions and gene copy-number alterations: A report from the Children's Oncology Group.
29691299 Clinical cancer research : an official journal of the American Association for Cancer Research, 2018 April 24

Ronsley R, Rassekh SR, Shen Y, Lee AF, Jantzen C, Halparin J, Albert C, Hawkins DS, Amed S, Rothstein R, Mungall AJ, Dix D, Blair G, Nadel H, Jones SJM, Laskin J, Marra MA, J Deyell R
Application of genomics to identify therapeutic targets in recurrent pediatric papillary thyroid carcinoma.
29610391 Cold Spring Harbor molecular case studies, 2018 April : 4(2) PMCID:PMC5880264

Laetsch TW, DuBois SG, Mascarenhas L, Turpin B, Federman N, Albert CM, Nagasubramanian R, Davis JL, Rudzinski E, Feraco AM, Tuch BB, Ebata KT, Reynolds M, Smith S, Cruickshank S, Cox MC, Pappo AS, Hawkins DS
Larotrectinib for paediatric solid tumours harbouring NTRK gene fusions: phase 1 results from a multicentre, open-label, phase 1/2 study.
29606586 The Lancet. Oncology, 2018 March 29

Drilon A, Laetsch TW, Kummar S, DuBois SG, Lassen UN, Demetri GD, Nathenson M, Doebele RC, Farago AF, Pappo AS, Turpin B, Dowlati A, Brose MS, Mascarenhas L, Federman N, Berlin J, El-Deiry WS, Baik C, Deeken J, Boni V, Nagasubramanian R, Taylor M, Rudzinski ER, Meric-Bernstam F, Sohal DPS, Ma PC, Raez LE, Hechtman JF, Benayed R, Ladanyi M, Tuch BB, Ebata K, Cruickshank S, Ku NC, Cox MC, Hawkins DS, Hong DS, Hyman DM
Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.
29466156 The New England journal of medicine, 2018 Feb. 22 : 378(8)731-739 PMCID:PMC5857389

Davis JL, Lockwood CM, Albert CM, Tsuchiya K, Hawkins DS, Rudzinski ER
Infantile NTRK-associated Mesenchymal Tumors.
28683589 Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, 2018 Jan. : 21(1)68-78

Weiss A, Hawkins D
Desmoid tumours in children: when wait-and-see becomes wait-and-treat.
30169177 The Lancet. Child & adolescent health, 2017 Dec. : 1(4)253-254

Rudzinski ER, Anderson JR, Chi YY, Gastier-Foster JM, Astbury C, Barr FG, Skapek SX, Hawkins DS, Weigel BJ, Pappo A, Meyer WH, Arnold MA, Teot LA, Parham DM
Histology, fusion status, and outcome in metastatic rhabdomyosarcoma: A report from the Children's Oncology Group.
28521080 Pediatric blood and cancer, 2017 Dec. : 64(12) PMCID:PMC5647228

Wang X, Sun CL, Hageman L, Smith K, Singh P, Desai S, Hawkins DS, Hudson MM, Mascarenhas L, Neglia JP, Oeffinger KC, Ritchey AK, Robison LL, Villaluna D, Landier W, Bhatia S
Clinical and Genetic Risk Prediction of Subsequent CNS Tumors in Survivors of Childhood Cancer: A Report From the COG ALTE03N1 Study.
28976792 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017 Nov. 10 : 35(32)3688-3696 PMCID:PMC5678343

Pinto N, Park JR, Murphy E, Yearley J, McClanahan T, Annamalai L, Hawkins DS, Rudzinski ER
Patterns of PD-1, PD-L1, and PD-L2 expression in pediatric solid tumors.
28488345 Pediatric blood and cancer, 2017 Nov. : 64(11)

Ren T, Piperdi S, Koirala P, Park A, Zhang W, Ivenitsky D, Zhang Y, Villanueva-Siles E, Hawkins DS, Roth M, Gorlick R
CD49b inhibits osteogenic differentiation and plays an important role in osteosarcoma progression.
29152125 Oncotarget, 2017 Oct. 20 : 8(50)87848-87859 PMCID:PMC5675677

Davis LE, Janeway KA, Weiss AR, Chen YE, Scharschmidt TJ, Krailo M, Glade Bender JL, Kopp LM, Patel SR, Schwartz GK, Horvath LE, Hawkins DS, Chuk MK, Reinke DK, Gorlick RG, Randall RL
Clinical trial enrollment of adolescents and young adults with sarcoma.
28493547 Cancer, 2017 Sept. 15 : 123(18)3434-3440 PMCID:PMC5650232

Gupta AA, Chi YY, Anderson JR, Lyden E, Weigel B, Arndt C, Meyer WH, Rosenberg A, Hawkins DS
Patterns of chemotherapy-induced toxicities and outcome in children and adolescents with metastatic rhabdomyosarcoma: A report from the Children's Oncology Group.
28333415 Pediatric blood and cancer, 2017 Sept. : 64(9) PMCID:PMC5567865

Ermoian RP, Breneman J, Walterhouse DO, Chi YY, Meza J, Anderson J, Hawkins DS, Hayes-Jordan AA, Parham DM, Yock TI, Donaldson SS, Wolden SL
45 Gy is not sufficient radiotherapy dose for Group III orbital embryonal rhabdomyosarcoma after less than complete response to 12 weeks of ARST0331 chemotherapy: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.
28548706 Pediatric blood and cancer, 2017 Sept. : 64(9) PMCID:PMC5568701

Walterhouse DO, Pappo AS, Meza JL, Breneman JC, Hayes-Jordan A, Parham DM, Cripe TP, Anderson JR, Meyer WH, Hawkins DS
Reduction of cyclophosphamide dose for patients with subset 2 low-risk rhabdomyosarcoma is associated with an increased risk of recurrence: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.
28211936 Cancer, 2017 June 15 : 123(12)2368-2375 PMCID:PMC5662934

Ferrari A, Chi YY, De Salvo GL, Orbach D, Brennan B, Randall RL, McCarville MB, Black JO, Alaggio R, Hawkins DS, Bisogno G, Spunt SL
Surgery alone is sufficient therapy for children and adolescents with low-risk synovial sarcoma: A joint analysis from the European paediatric soft tissue sarcoma Study Group and the Children's Oncology Group.
28391003 European journal of cancer (Oxford, England : 1990), 2017 June : 781-6 PMCID:PMC5567853

Cross NM, Stanescu AL, Rudzinski ER, Hawkins DS, Parisi MT
Vaginal Ewing Sarcoma: An Uncommon Clinical Entity in Pediatric Patients.
28589056 Journal of clinical imaging science, 2017 : 717 PMCID:PMC5433652

Marina NM, Smeland S, Bielack SS, Bernstein M, Jovic G, Krailo MD, Hook JM, Arndt C, van den Berg H, Brennan B, Brichard B, Brown KLB, Butterfass-Bahloul T, Calaminus G, Daldrup-Link HE, Eriksson M, Gebhardt MC, Gelderblom H, Gerss J, Goldsby R, Goorin A, Gorlick R, Grier HE, Hale JP, Hall KS, Hardes J, Hawkins DS, Helmke K, Hogendoorn PCW, Isakoff MS, Janeway KA, JÃ¼rgens H, Kager L, KÃ¼hne T, Lau CC, Leavey PJ, Lessnick SL, Mascarenhas L, Meyers PA, Mottl H, Nathrath M, Papai Z, Randall RL, Reichardt P, Renard M, Safwat AA, Schwartz CL, Stevens MCG, Strauss SJ, Teot L, Werner M, Sydes MR, Whelan JS
Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial.
27569442 The Lancet. Oncology, 2016 Oct. : 17(10)1396-1408 PMCID:PMC5052459

Xu L, Wilson RA, Laetsch TW, Oliver D, Spunt SL, Hawkins DS, Skapek SX
Potential pitfalls of mass spectrometry to uncover mutations in childhood soft tissue sarcoma: A report from the Children's Oncology Group.
27642091 Scientific reports, 2016 Sept. 19 : 633429 PMCID:PMC5027578

Lagmay JP, Krailo MD, Dang H, Kim A, Hawkins DS, Beaty O 3rd, Widemann BC, Zwerdling T, Bomgaars L, Langevin AM, Grier HE, Weigel B, Blaney SM, Gorlick R, Janeway KA
Outcome of Patients With Recurrent Osteosarcoma Enrolled in Seven Phase II Trials Through Children's Cancer Group, Pediatric Oncology Group, and Children's Oncology Group: Learning From the Past to Move Forward.
27400942 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016 Sept. 1 : 34(25)3031-8 PMCID:PMC5012712

Black JO, Coffin CM, Parham DM, Hawkins DS, Speights RA, Spunt SL
Opportunities for Improvement in Pathology Reporting of Childhood Nonrhabdomyosarcoma Soft Tissue Sarcomas: â€‰A Report From Children's Oncology Group (COG) Study ARST0332.
27510717 American journal of clinical pathology, 2016 Sept. : 146(3)328-38

Sankaran H, Danysh HE, Scheurer ME, Okcu MF, Skapek SX, Hawkins DS, Spector LG, Erhardt EB, Grufferman S, Lupo PJ
The Role of Childhood Infections and Immunizations on Childhood Rhabdomyosarcoma: A Report From the Children's Oncology Group.
27198935 Pediatric blood and cancer, 2016 Sept. : 63(9)1557-62 PMCID:PMC4955701

Serrero G, Hawkins DM, Bejarano PA, Ioffe O, Tkaczuk KR, Elliott RE, Head JF, Phillips J, Godwin AK, Weaver J, Hicks D, Yue B
Determination of GP88 (progranulin) expression in breast tumor biopsies improves the risk predictive value of the Nottingham Prognostic Index.
27501955 Diagnostic pathology, 2016 Aug. 8 : 11(1)71 PMCID:PMC4977669

Vo KT, Edwards JV, Epling CL, Sinclair E, Hawkins DS, Grier HE, Janeway KA, Barnette P, McIlvaine E, Krailo MD, Barkauskas DA, Matthay KK, Womer RB, Gorlick RG, Lessnick SL, Mackall CL, DuBois SG
Impact of Two Measures of Micrometastatic Disease on Clinical Outcomes in Patients with Newly Diagnosed Ewing Sarcoma: A Report from the Children's Oncology Group.
26861456 Clinical cancer research : an official journal of the American Association for Cancer Research, 2016 July 15 : 22(14)3643-50 PMCID:PMC4947459

Hingorani P, Janeway K, Crompton BD, Kadoch C, Mackall CL, Khan J, Shern JF, Schiffman J, Mirabello L, Savage SA, Ladanyi M, Meltzer P, Bult CJ, Adamson PC, Lupo PJ, Mody R, DuBois SG, Parsons DW, Khanna C, Lau C, Hawkins DS, Randall RL, Smith M, Sorensen PH, Plon SE, Skapek SX, Lessnick S, Gorlick R, Reed DR
Current state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop.
27132463 Cancer genetics, 2016 May : 209(5)182-94 PMCID:PMC5497490

Arnold MA, Anderson JR, Gastier-Foster JM, Barr FG, Skapek SX, Hawkins DS, Raney RB Jr, Parham DM, Teot LA, Rudzinski ER, Walterhouse DO
Histology, Fusion Status, and Outcome in Alveolar Rhabdomyosarcoma With Low-Risk Clinical Features: A Report From the Children's Oncology Group.
26756883 Pediatric blood and cancer, 2016 April : 63(4)634-9 PMCID:PMC4755849

Richards MK, Dahl JP, Gow K, Goldin AB, Doski J, Goldfarb M, Nuchtern J, Langer M, Beierle EA, Vasudevan S, Hawkins DS, Parikh SR
Factors Associated With Mortality in Pediatric vs Adult Nasopharyngeal Carcinoma.
26769566 JAMA otolaryngology-- head and neck surgery, 2016 March : 142(3)217-22

Vo KT, Edwards JV, Epling CL, Sinclair E, Hawkins DS, Grier HE, Janeway KA, Barnette P, McIlvaine E, Krailo M, Barkauskas DA, Matthay KK, Womer RB, Gorlick R, Lessnick SL, Mackall CL, Dubois SG
Impact of Two Measures of Micrometastatic Disease on Clinical Outcomes in Patients with Newly Diagnosed Ewing Sarcoma: A Report from the Children's Oncology Group.
26861456 Clinical cancer research : an official journal of the American Association for Cancer Research, 2016 Feb. 9

Pinto N, Hawkins DS
Second Malignant Neoplasms in Rhabdomyosarcoma: Victims of Our Own Success or an Underlying Genetic Predisposition Syndrome?
26505490 Pediatric blood and cancer, 2016 Feb. : 63(2)189-90

Weigel BJ, Lyden E, Anderson JR, Meyer WH, Parham DM, Rodeberg DA, Michalski JM, Hawkins DS, Arndt CA
Intensive Multiagent Therapy, Including Dose-Compressed Cycles of Ifosfamide/Etoposide and Vincristine/Doxorubicin/Cyclophosphamide, Irinotecan, and Radiation, in Patients With High-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group.
26503200 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016 Jan. 10 : 34(2)117-22 PMCID:PMC5070550

Wolden SL, Lyden ER, Arndt CA, Hawkins DS, Anderson JR, Rodeberg DA, Morris CD, Donaldson SS
Local Control for Intermediate-Risk Rhabdomyosarcoma: Results From D9803 According to Histology, Group, Site, and Size: A Report From the Children's Oncology Group.
26581144 International journal of radiation oncology, biology, physics, 2015 Dec. 1 : 93(5)1071-6 PMCID:PMC5147527

Oberlin O, Rey A, Brown KL, Bisogno G, Koscielniak E, Stevens MC, Hawkins DS, Meyer WH, La TH, Carli M, Anderson JR
Prognostic Factors for Outcome in Localized Extremity Rhabdomyosarcoma. Pooled Analysis from Four International Cooperative Groups.
26257045 Pediatric blood and cancer, 2015 Dec. : 62(12)2125-31 PMCID:PMC5002346

Hingorani P, Missiaglia E, Shipley J, Anderson JR, Triche TJ, Delorenzi M, Gastier-Foster J, Wing M, Hawkins DS, Skapek SX
Clinical Application of Prognostic Gene Expression Signature in Fusion Gene-Negative Rhabdomyosarcoma: A Report from the Children's Oncology Group.
26473193 Clinical cancer research : an official journal of the American Association for Cancer Research, 2015 Oct. 15 : 21(20)4733-9 PMCID:PMC4610152

Rudzinski ER, Anderson JR, Hawkins DS, Skapek SX, Parham DM, Teot LA
The World Health Organization Classification of Skeletal Muscle Tumors in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group.
25989287 Archives of pathology and laboratory medicine, 2015 Oct. : 139(10)1281-7 PMCID:PMC4651658

Gaspar N, Hawkins DS, Dirksen U, Lewis IJ, Ferrari S, Le Deley MC, Kovar H, Grimer R, Whelan J, Claude L, Delattre O, Paulussen M, Picci P, Sundby Hall K, van den Berg H, Ladenstein R, Michon J, Hjorth L, Judson I, Luksch R, Bernstein ML, Marec-BÃ©rard P, Brennan B, Craft AW, Womer RB, Juergens H, Oberlin O
Ewing Sarcoma: Current Management and Future Approaches Through Collaboration.
26304893 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015 Sept. 20 : 33(27)3036-46

Sargar K, Kao SC, Spunt SL, Hawkins DS, Parham DM, Coffin C, McCarville MB
MRI and CT of Low-Grade Fibromyxoid Sarcoma in Children: A Report From Children's Oncology Group Study ARST0332.
26204295 AJR. American journal of roentgenology, 2015 Aug. : 205(2)414-20 PMCID:PMC4570741

Bielack SS, Smeland S, Whelan JS, Marina N, Jovic G, Hook JM, Krailo MD, Gebhardt M, PÃ¡pai Z, Meyer J, Nadel H, Randall RL, Deffenbaugh C, Nagarajan R, Brennan B, Letson GD, Teot LA, Goorin A, Baumhoer D, Kager L, Werner M, Lau CC, Sundby Hall K, Gelderblom H, Meyers P, Gorlick R, Windhager R, Helmke K, Eriksson M, Hoogerbrugge PM, Schomberg P, Tunn PU, KÃ¼hne T, JÃ¼rgens H, van den Berg H, BÃ¶hling T, Picton S, Renard M, Reichardt P, Gerss J, Butterfass-Bahloul T, Morris C, Hogendoorn PC, Seddon B, Calaminus G, Michelagnoli M, Dhooge C, Sydes MR, Bernstein M, EURAMOS-1 investigators.
Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial.
26033801 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015 July 10 : 33(20)2279-87 PMCID:PMC4486345

Rodeberg DA, Wharam MD, Lyden ER, Stoner JA, Brown K, Wolden SL, Paidas CN, Donaldson SS, Hawkins DS, Spunt SL, Arndt CA
Delayed primary excision with subsequent modification of radiotherapy dose for intermediate-risk rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee.
25418440 International journal of cancer, 2015 July 1 : 137(1)204-11 PMCID:PMC4474372

Lupo PJ, Danysh HE, Plon SE, Curtin K, Malkin D, Hettmer S, Hawkins DS, Skapek SX, Spector LG, Papworth K, Melin B, Erhardt EB, Grufferman S, Schiffman JD
Family history of cancer and childhood rhabdomyosarcoma: a report from the Children's Oncology Group and the Utah Population Database.
25809884 Cancer medicine, 2015 May : 4(5)781-90 PMCID:PMC4430270

Chen L, Shern JF, Wei JS, Yohe ME, Song YK, Hurd L, Liao H, Catchpoole D, Skapek SX, Barr FG, Hawkins DS, Khan J
Clonality and evolutionary history of rhabdomyosarcoma.
25768946 PLoS genetics, 2015 March : 11(3)e1005075 PMCID:PMC4358975

Gensheimer MF, Hawkins DS, Ermoian RP, Trister AD
Assessing the scale of tumor heterogeneity by complete hierarchical segmentation of MRI.
25575341 Physics in medicine and biology, 2015 Feb. 7 : 60(3)977-93

Poon VI, Roth M, Piperdi S, Geller D, Gill J, Rudzinski ER, Hawkins DS, Gorlick R
Ganglioside GD2 expression is maintained upon recurrence in patients with osteosarcoma.
25642322 Clinical sarcoma research, 2015 : 5(1)4 PMCID:PMC4311500

Walterhouse DO, Pappo AS, Meza JL, Breneman JC, Hayes-Jordan AA, Parham DM, Cripe TP, Anderson JR, Meyer WH, Hawkins DS
Shorter-duration therapy using vincristine, dactinomycin, and lower-dose cyclophosphamide with or without radiotherapy for patients with newly diagnosed low-risk rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.
25267746 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014 Nov. 1 : 32(31)3547-52 PMCID:PMC4209105

Lupo PJ, Danysh HE, Skapek SX, Hawkins DS, Spector LG, Zhou R, Okcu MF, Papworth K, Erhardt EB, Grufferman S
Maternal and birth characteristics and childhood rhabdomyosarcoma: a report from the Children's Oncology Group.
24831857 Cancer causes and control : CCC, 2014 July : 25(7)905-13 PMCID:PMC4091713

Rudzinski ER, Anderson JR, Lyden ER, Bridge JA, Barr FG, Gastier-Foster JM, Bachmeyer K, Skapek SX, Hawkins DS, Teot LA, Parham DM
Myogenin, AP2, NOS-1, and HMGA2 Are Surrogate Markers of Fusion Status in Rhabdomyosarcoma: A Report From the Soft Tissue Sarcoma Committee of the Children's Oncology Group.
24618610 The American journal of surgical pathology, 2014 March 10

Rosenberg AR, Anderson JR, Lyden E, Rodeberg DA, Wolden SL, Kao SC, Parham DM, Arndt C, Hawkins DS
Early response as assessed by anatomic imaging does not predict failure-free survival among patients with Group III rhabdomyosarcoma: a report from the Children's Oncology Group.
24361229 European journal of cancer (Oxford, England : 1990), 2014 March : 50(4)816-23 PMCID:PMC3944684

Hawkins DS, Gupta AA, Rudzinski ER
What is new in the biology and treatment of pediatric rhabdomyosarcoma?
24326270 Current opinion in pediatrics, 2014 Feb. : 26(1)50-6 PMCID:PMC4096484

Shern JF, Chen L, Chmielecki J, Wei JS, Patidar R, Rosenberg M, Ambrogio L, Auclair D, Wang J, Song YK, Tolman C, Hurd L, Liao H, Zhang S, Bogen D, Brohl AS, Sindiri S, Catchpoole D, Badgett T, Getz G, Mora J, Anderson JR, Skapek SX, Barr FG, Meyerson M, Hawkins DS, Khan J
Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors.
24436047 Cancer discovery, 2014 Feb. : 4(2)216-31

Russell H, Swint JM, Lal L, Meza J, Walterhouse D, Hawkins DS, Okcu MF
Cost minimization analysis of two treatment regimens for low-risk rhabdomyosarcoma in children: A report from the Children's Oncology Group.
24453105 Pediatric blood & cancer, 2014 Jan. 22

Eary JF, Conrad EU, O'Sullivan J, Hawkins DS, Schuetze SM, O'Sullivan F
Sarcoma mid-therapy [F-18]fluorodeoxyglucose positron emission tomography (FDG PET) and patient outcome.
24430415 The Journal of bone and joint surgery. American volume, 2014 Jan. 15 : 96(2)152-8 PMCID:PMC3903137

Lupo PJ, Zhou R, Skapek SX, Hawkins DS, Spector LG, Scheurer ME, Fatih Okcu M, Melin B, Papworth K, Erhardt EB, Grufferman S
Allergies, atopy, immune-related factors and childhood rhabdomyosarcoma: a report from the Children's Oncology Group.
23824786 International journal of cancer. Journal international du cancer, 2014 Jan. 15 : 134(2)431-6 PMCID:PMC3869863

Chen X, Stewart E, Shelat AA, Qu C, Bahrami A, Hatley M, Wu G, Bradley C, McEvoy J, Pappo A, Spunt S, Valentine MB, Valentine V, Krafcik F, Lang WH, Wierdl M, Tsurkan L, Tolleman V, Federico SM, Morton C, Lu C, Ding L, Easton J, Rusch M, Nagahawatte P, Wang J, Parker M, Wei L, Hedlund E, Finkelstein D, Edmonson M, Shurtleff S, Boggs K, Mulder H, Yergeau D, Skapek S, Hawkins DS, Ramirez N, Potter PM, Sandoval JA, Davidoff AM, Mardis ER, Wilson RK, Zhang J, Downing JR, Dyer MA, St. Jude Childrens Research HospitalWashington University Pediatric Cancer Genome Project
Targeting oxidative stress in embryonal rhabdomyosarcoma.
24332040 Cancer cell, 2013 Dec. 9 : 24(6)710-24 PMCID:PMC3904731

Spalding AC, Hawkins DS, Donaldson SS, Anderson JR, Lyden E, Laurie F, Wolden SL, Arndt CA, Michalski JM
The effect of radiation timing on patients with high-risk features of parameningeal rhabdomyosarcoma: an analysis of IRS-IV and D9803.
24074925 International journal of radiation oncology, biology, physics, 2013 Nov. 1 : 87(3)512-6

Wilson RA, Teng L, Bachmeyer KM, Bissonnette ML, Husain AN, Parham DM, Triche TJ, Wing MR, Gastier-Foster JM, Barr FG, Hawkins DS, Anderson JR, Skapek SX, Volchenboum SL
A novel algorithm for simplification of complex gene classifiers in cancer.
23913937 Cancer research, 2013 Sept. 15 : 73(18)5625-32

Weiss AR, Lyden ER, Anderson JR, Hawkins DS, Spunt SL, Walterhouse DO, Wolden SL, Parham DM, Rodeberg DA, Kao SC, Womer RB
Histologic and clinical characteristics can guide staging evaluations for children and adolescents with rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee.
23940218 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013 Sept. 10 : 31(26)3226-32 PMCID:PMC3757291

Skapek SX, Anderson J, Barr FG, Bridge JA, Gastier-Foster JM, Parham DM, Rudzinski ER, Triche T, Hawkins DS
PAX-FOXO1 fusion status drives unfavorable outcome for children with rhabdomyosarcoma: a children's oncology group report.
23526739 Pediatric blood & cancer, 2013 Sept. : 60(9)1411-7

Lupo PJ, Zhou R, Skapek SX, Hawkins DS, Spector LG, Scheurer ME, Fatih Okcu M, Melin B, Papworth K, Erhardt EB, Grufferman S
Allergies, atopy, immune-related factors and childhood rhabdomyosarcoma: A report from the children's oncology group.
23824786 International journal of cancer. Journal international du cancer, 2013 July 3

Skapek SX, Anderson JR, Hill DA, Henry D, Spunt SL, Meyer W, Kao S, Hoffer FA, Grier HE, Hawkins DS, Raney RB
Safety and efficacy of high-dose tamoxifen and sulindac for desmoid tumor in children: results of a Children's Oncology Group (COG) phase II study.
23281268 Pediatric blood & cancer, 2013 July : 60(7)1108-12

Rudzinski ER, Teot LA, Anderson JR, Moore J, Bridge JA, Barr FG, Gastier-Foster JM, Skapek SX, Hawkins DS, Parham DM
Dense pattern of embryonal rhabdomyosarcoma, a lesion easily confused with alveolar rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.
23765537 American journal of clinical pathology, 2013 July : 140(1)82-90

Skapek SX, Anderson JR, Hill DA, Henry D, Spunt SL, Meyer W, Kao S, Hoffer FA, Grier HE, Hawkins DS, Raney RB
Safety and efficacy of high-dose tamoxifen and sulindac for desmoid tumor in children: results of a Children's Oncology Group (COG) phase II study.
23281268 Pediatric blood & cancer, 2013 July : 60(7)1108-12

Newman EN, Jones RL, Hawkins DS
An evaluation of [F-18]-fluorodeoxy-D-glucose positron emission tomography, bone scan, and bone marrow aspiration/biopsy as staging investigations in Ewing sarcoma.
23192939 Pediatric blood & cancer, 2013 July : 60(7)1113-7

Hawkins DS, Spunt SL, Skapek SX, COG Soft Tissue Sarcoma Committee
Children's Oncology Group's 2013 blueprint for research: Soft tissue sarcomas.
23255356 Pediatric blood & cancer, 2013 June : 60(6)1001-8 PMCID:PMC3777409

Raney B, Huh W, Hawkins D, Hayes-Jordan A, Million L, Rodeberg D, Teot L, Anderson J, Soft Tissue Sarcoma Committee of the Children's Oncology Group, Arcadia, CA
Outcome of patients with localized orbital sarcoma who relapsed following treatment on Intergroup Rhabdomyosarcoma Study Group (IRSG) Protocols-III and -IV, 1984-1997: a report from the Children's Oncology Group.
22961750 Pediatric blood & cancer, 2013 March : 60(3)371-6

MacQuarrie KL, Yao Z, Fong AP, Diede SJ, Rudzinski ER, Hawkins DS, Tapscott SJ
Comparison of genome-wide binding of MyoD in normal human myogenic cells and rhabdomyosarcomas identifies regional and local suppression of promyogenic transcription factors.
23230269 Molecular and cellular biology, 2013 Feb. : 33(4)773-84 PMCID:PMC3571334

Gardner RA, Thomson B, Hawkins DS
Substitution with doxorubicin for daunorubicin during induction for high risk pediatric acute lymphoblastic leukemia results in increased toxicity.
23015453 Pediatric blood & cancer, 2013 Feb. : 60(2)338-9

Soundararajan A, Abraham J, Nelon LD, Prajapati SI, Zarzabal LA, Michalek JE, McHardy SF, Hawkins DS, Malempati S, Keller C
18F-FDG microPET imaging detects early transient response to an IGF1R inhibitor in genetically engineered rhabdomyosarcoma models.
22238194 Pediatric blood & cancer, 2012 Sept. : 59(3)485-92

Malempati S, Hawkins DS
Rhabdomyosarcoma: review of the Children's Oncology Group (COG) Soft-Tissue Sarcoma Committee experience and rationale for current COG studies.
22378628 Pediatric blood & cancer, 2012 July 15 : 59(1)5-10

Rosenberg AR, Skapek SX, Hawkins DS
The inconvenience of convenience cohorts: rhabdomyosarcoma and the PAX-FOXO1 biomarker.
22564868 Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2012 July : 21(7)1012-8 PMCID:PMC3392538

Spunt SL, Vargas SO, Coffin CM, Skapek SX, Parham DM, Darling J, Hawkins DS, Keller C
The clinical, research, and social value of autopsy after any cancer death: a perspective from the Children's Oncology Group Soft Tissue Sarcoma Committee.
22006470 Cancer, 2012 June 15 : 118(12)3002-9 PMCID:PMC3274663

Breneman J, Meza J, Donaldson SS, Raney RB, Wolden S, Michalski J, Laurie F, Rodeberg DA, Meyer W, Walterhouse D, Hawkins DS
Local control with reduced-dose radiotherapy for low-risk rhabdomyosarcoma: a report from the Children's Oncology Group D9602 study.
22104356 International journal of radiation oncology, biology, physics, 2012 June 1 : 83(2)720-6 PMCID:PMC3305826

Gupta AA, Anderson JR, Pappo AS, Spunt SL, Dasgupta R, Indelicato DJ, Hawkins DS
Patterns of chemotherapy-induced toxicities in younger children and adolescents with rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee.
21761400 Cancer, 2012 Feb. 15 : 118(4)1130-7

Raccor BS, Claessens AJ, Dinh JC, Park JR, Hawkins DS, Thomas SS, Makar KW, McCune JS, Totah RA
Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo.
21976622 Drug metabolism and disposition: the biological fate of chemicals, 2012 Jan. : 40(1)54-63 PMCID:PMC3250049

Hingorani P, Seidel K, Krailo M, Mascarenhas L, Meyers P, Marina N, Conrad EU, Hawkins DS
Body mass index (BMI) at diagnosis is associated with surgical wound complications in patients with localized osteosarcoma: a report from the Children's Oncology Group.
21480474 Pediatric blood & cancer, 2011 Dec. 1 : 57(6)939-42 PMCID:PMC3135763

Hawkins DS
Sarcomas gone bad: what to do about recurrent Ewing sarcoma.
21681926 Pediatric blood & cancer, 2011 Oct. : 57(4)535-6

Stephenson J, Gow KW, Meehan J, Hawkins DS, Avansino J
Ewing sarcoma/primitive neuroectodermal tumor arising from the adrenal gland in an adolescent.
21681923 Pediatric blood & cancer, 2011 Oct. : 57(4)691-2

Malempati S, Rodeberg DA, Donaldson SS, Lyden ER, Anderson JR, Hawkins DS, Arndt CA
Rhabdomyosarcoma in infants younger than 1 year: a report from the Children's Oncology Group.
21264837 Cancer, 2011 Aug. 1 : 117(15)3493-501 PMCID:PMC3140625

Foster JH, Hawkins DS, Loken MR, Wells DA, Thomson B
Minimal residual disease detected prior to hematopoietic cell transplantation.
21370437 Pediatric blood & cancer, 2011 July 15 : 57(1)163-5

Walterhouse DO, Meza JL, Breneman JC, Donaldson SS, Hayes-Jordan A, Pappo AS, Arndt C, Raney RB, Meyer WH, Hawkins DS
Local control and outcome in children with localized vaginal rhabdomyosarcoma: a report from the Soft Tissue Sarcoma committee of the Children's Oncology Group.
21298768 Pediatric blood & cancer, 2011 July 15 : 57(1)76-83 PMCID:PMC3459820

La TH, Wolden SL, Rodeberg DA, Hawkins DS, Brown KL, Anderson JR, Donaldson SS
Regional nodal involvement and patterns of spread along in-transit pathways in children with rhabdomyosarcoma of the extremity: a report from the Children's Oncology Group.
20542386 International journal of radiation oncology, biology, physics, 2011 July 15 : 80(4)1151-7 PMCID:PMC3116031

Million L, Anderson J, Breneman J, Hawkins DS, Laurie F, Michalski J, Rodeberg D, Wharam M, Wolden S, Donaldson SS, Soft Tissue Sarcoma Committee of the Children's Oncology Group
Influence of noncompliance with radiation therapy protocol guidelines and operative bed recurrences for children with rhabdomyosarcoma and microscopic residual disease: a report from the Children's Oncology Group.
20646841 International journal of radiation oncology, biology, physics, 2011 June 1 : 80(2)333-8

Rodeberg DA, Stoner JA, Garcia-Henriquez N, Randall RL, Spunt SL, Arndt CA, Kao S, Paidas CN, Million L, Hawkins DS
Tumor volume and patient weight as predictors of outcome in children with intermediate risk rhabdomyosarcoma: a report from the Children's Oncology Group.
24048802 Cancer, 2011 June 1 : 117(11)2541-50 PMCID:PMC3117103

La TH, Wolden SL, Su Z, Linardic C, Randall RL, Hawkins DS, Donaldson SS
Local therapy for rhabdomyosarcoma of the hands and feet: is amputation necessary? A report from the Children's Oncology Group.
20646853 International journal of radiation oncology, biology, physics, 2011 May 1 : 80(1)206-12 PMCID:PMC3075377

Rodeberg DA, Garcia-Henriquez N, Lyden ER, Davicioni E, Parham DM, Skapek SX, Hayes-Jordan AA, Donaldson SS, Brown KL, Triche TJ, Meyer WH, Hawkins DS
Prognostic significance and tumor biology of regional lymph node disease in patients with rhabdomyosarcoma: a report from the Children's Oncology Group.
21357792 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011 April 1 : 29(10)1304-11 PMCID:PMC3083998

Eary JF, Hawkins DS, Rodler ET, Conrad EU 3rd
(18)F-FDG PET in sarcoma treatment response imaging.
23133794 American journal of nuclear medicine and molecular imaging, 2011 : 1(1)47-53 PMCID:PMC3477719

Rodeberg DA, Stoner JA, Garcia-Henriquez N, Randall RL, Spunt SL, Arndt CA, Kao S, Paidas CN, Million L, Hawkins DS
Tumor volume and patient weight as predictors of outcome in children with intermediate risk rhabdomyosarcoma: a report from the children's oncology group.
21157950 Cancer, 2010 Dec. 14

Mascarenhas L, Lyden ER, Breitfeld PP, Walterhouse DO, Donaldson SS, Paidas CN, Parham DM, Anderson JR, Meyer WH, Hawkins DS
Randomized phase II window trial of two schedules of irinotecan with vincristine in patients with first relapse or progression of rhabdomyosarcoma: a report from the Children's Oncology Group.
20837952 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010 Oct. 20 : 28(30)4658-63 PMCID:PMC2974343

Anderson JR, Barr FG, Hawkins DS, Parham DM, Skapek SX, Triche TJ
Fusion-negative alveolar rhabdomyosarcoma: modification of risk stratification is premature.
20697086 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010 Oct. 10 : 28(29)e587-8; author reply e589-90

Minn AY, Lyden ER, Anderson JR, Million L, Arndt CA, Brown K, Hawkins DS, Donaldson SS
Early treatment failure in intermediate-risk rhabdomyosarcoma: results from IRS-IV and D9803--a report from the Children's Oncology Group.
20713850 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010 Sept. 20 : 28(27)4228-32 PMCID:PMC2953975

Arndt CA, Koshkina NV, Inwards CY, Hawkins DS, Krailo MD, Villaluna D, Anderson PM, Goorin AM, Blakely ML, Bernstein M, Bell SA, Ray K, Grendahl DC, Marina N, Kleinerman ES
Inhaled granulocyte-macrophage colony stimulating factor for first pulmonary recurrence of osteosarcoma: effects on disease-free survival and immunomodulation. a report from the Children's Oncology Group.
20576718 Clinical cancer research : an official journal of the American Association for Cancer Research, 2010 Aug. 1 : 16(15)4024-30 PMCID:PMC2989183

Koschmann C, Thomson B, Hawkins DS
No evidence of a trial effect in newly diagnosed pediatric acute lymphoblastic leukemia.
20194252 Archives of pediatrics & adolescent medicine, 2010 March : 214-7

Schmale GA, Hawkins DS, Rutledge J, Conrad EU
Malignant progression in two children with multiple osteochondromas.
20467466 Sarcoma, 2010 : 2010417105 PMCID:PMC2866243

Fox E, Widemann BC, Hawkins DS, Jayaprakash N, Dagher R, Aikin AA, Bernstein D, Long L, Mackall C, Helman L, Steinberg SM, Balis FM
Randomized trial and pharmacokinetic study of pegfilgrastim versus filgrastim after dose-intensive chemotherapy in young adults and children with sarcomas.
19920107 Clinical cancer research : an official journal of the American Association for Cancer Research, 2009 Dec. 1 : 15(23)7361-7 PMCID:PMC2787766

Arndt CA, Stoner JA, Hawkins DS, Rodeberg DA, Hayes-Jordan AA, Paidas CN, Parham DM, Teot LA, Wharam MD, Breneman JC, Donaldson SS, Anderson JR, Meyer WH
Vincristine, actinomycin, and cyclophosphamide compared with vincristine, actinomycin, and cyclophosphamide alternating with vincristine, topotecan, and cyclophosphamide for intermediate-risk rhabdomyosarcoma: children's oncology group study D9803.
19770373 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009 Nov. 1 : 27(31)5182-8 PMCID:PMC2773476

Borinstein SC, Pollard J, Winter L, Hawkins DS
Pegfilgrastim for prevention of chemotherapy-associated neutropenia in pediatric patients with solid tumors.
19484756 Pediatric blood & cancer, 2009 Sept. : 53(3)375-8

Rodeberg DA, Stoner JA, Hayes-Jordan A, Kao SC, Wolden SL, Qualman SJ, Meyer WH, Hawkins DS
Prognostic significance of tumor response at the end of therapy in group III rhabdomyosarcoma: a report from the children's oncology group.
19470937 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009 Aug. 1 : 3705-11

Rodeberg DA, Stoner JA, Hayes-Jordan A, Kao SC, Wolden SL, Qualman SJ, Meyer WH, Hawkins DS
Prognostic significance of tumor response at the end of therapy in group III rhabdomyosarcoma: a report from the children's oncology group.
19470937 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009 Aug. 1 : 27(22)3705-11 PMCID:PMC3020959

Hawkins DS, Conrad EU 3rd, Butrynski JE, Schuetze SM, Eary JF
[F-18]-fluorodeoxy-D-glucose-positron emission tomography response is associated with outcome for extremity osteosarcoma in children and young adults.
19517457 Cancer, 2009 Aug. 1 : 115(15)3519-25 PMCID:PMC2716419

Imran H, Enders F, Krailo M, Sim F, Okuno S, Hawkins D, Neglia J, Randall RL, Womer R, Mascarenhas L, Arndt CA
Effect of time to resumption of chemotherapy after definitive surgery on prognosis for non-metastatic osteosarcoma.
19255220 The Journal of bone and joint surgery. American volume, 2009 March 1 : 91(3)604-12 PMCID:PMC2701597

Cengiz P, Zemlan F, Ellenbogen R, Hawkins D, Zimmerman JJ
Cerebrospinal fluid cleaved-tau protein and 9-hydroxyoctadecadienoic acid concentrations in pediatric patients with hydrocephalus.
18679140 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2008 Sept. : 9(5)524-9

Rodriguez NI, Hoots WK, Koshkina NV, Morales-Arias JA, Arndt CA, Inwards CY, Hawkins DS, Munsell MF, Kleinerman ES
COX-2 expression correlates with survival in patients with osteosarcoma lung metastases.
18797196 Journal of pediatric hematology/oncology, 2008 July : 30(7)507-12 PMCID:PMC2771732

Wirojanan J, Kraff J, Hawkins DS, Laird C, Gane LW, Angkustsiri K, Tassone F, Hagerman RJ
Two boys with fragile x syndrome and hepatic tumors.
18376289 Journal of pediatric hematology/oncology, 2008 March : 30(3)239-41

Borinstein SC, Xu M, Hawkins DS
Methemoglobinemia and hemolytic anemia caused by rasburicase administration in a newly diagnosed child with Burkitt lymphoma/leukemia.
17387701 Pediatric blood & cancer, 2008 Jan. : 50(1)189

Arndt CA, Hawkins DS, Meyer WH, Sencer SF, Neglia JP, Anderson JR
Comparison of results of a pilot study of alternating vincristine/doxorubicin/cyclophosphamide and etoposide/ifosfamide with IRS-IV in intermediate risk rhabdomyosarcoma: a report from the Children's Oncology Group.
17091486 Pediatric blood & cancer, 2008 Jan. : 50(1)33-6

Douglas JG, Arndt CA, Hawkins DS
Delayed radiotherapy following dose intensive chemotherapy for parameningeal rhabdomyosarcoma (PM-RMS) of childhood.
17368885 European journal of cancer (Oxford, England : 1990), 2007 April : 43(6)1045-50

Greene S, Hawkins DS, Rutledge JC, Tsuchiya KD, Douglas J, Ellenbogen RG, Avellino AM
Pediatric intradural extramedullary synovial sarcoma: case report.
17277671 Neurosurgery, 2006 Dec. : E1339; discussion E1339

Hawkins DS, Bradfield S, Whitlock JA, Krailo M, Franklin J, Blaney SM, Adamson PC, Reaman G
Topotecan by 21-day continuous infusion in children with relapsed or refractory solid tumors: a Children's Oncology Group study.
16435380 Pediatric blood & cancer, 2006 Nov. : 47(6)790-4

Taylor JA, Winter L, Geyer LJ, Hawkins DS
Oral outpatient chemotherapy medication errors in children with acute lymphoblastic leukemia.
16909415 Cancer, 2006 Sept. 15 : 107(6)1400-6

Morgan HD, Cizik AM, Leopold SS, Hawkins DS, Conrad EU 3rd
Survival of tumor megaprostheses replacements about the knee.
16906094 Clinical orthopaedics and related research, 2006 Sept. : 45039-45

Hawkins DS, Schuetze SM, Butrynski JE, Rajendran JG, Vernon CB, Conrad EU 3rd, Eary JF
[18F]Fluorodeoxyglucose positron emission tomography predicts outcome for Ewing sarcoma family of tumors.
16314643 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005 Dec. 1 : 23(34)8828-34

Cole PD, Drachtman RA, Smith AK, Cate S, Larson RA, Hawkins DS, Holcenberg J, Kelly K, Kamen BA
Phase II trial of oral aminopterin for adults and children with refractory acute leukemia.
16299240 Clinical cancer research : an official journal of the American Association for Cancer Research, 2005 Nov. 15 : 11(22)8089-96 PMCID:PMC2906753

Gordon N, Arndt CA, Hawkins DS, Doherty DK, Inwards CY, Munsell MF, Stewart J, Koshkina NV, Kleinerman ES
Fas expression in lung metastasis from osteosarcoma patients.
16282894 Journal of pediatric hematology/oncology, 2005 Nov. : 27(11)611-5

Spiller SE, Hawkins DS, Finn LS, Sze RW, Sybert V
Metastatic malignant melanoma presenting as pancytopenia in a three-year-old boy.
15800910 Pediatric blood & cancer, 2005 July : 45(1)60-3

Barker LM, Pendergrass TW, Sanders JE, Hawkins DS
Survival after recurrence of Ewing's sarcoma family of tumors.
15781881 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005 July 1 : 23(19)4354-62

Schuetze SM, Rubin BP, Vernon C, Hawkins DS, Bruckner JD, Conrad EU 3rd, Eary JF
Use of positron emission tomography in localized extremity soft tissue sarcoma treated with neoadjuvant chemotherapy.
15578712 Cancer, 2005 Jan. 15 : 103(2)339-48

Hawkins DS
Transatlantic collaboration in pediatric oncology: now is the time.
15591895 Journal of pediatric hematology/oncology, 2004 Dec. : 26(12)783-4

Thomson B, Park JR, Felgenhauer J, Meshinchi S, Holcenberg J, Geyer JR, Avramis V, Douglas JG, Loken MR, Hawkins DS
Toxicity and efficacy of intensive chemotherapy for children with acute lymphoblastic leukemia (ALL) after first bone marrow or extramedullary relapse.
15382275 Pediatric blood & cancer, 2004 Oct. : 571-9

Hawkins DS, Park JR, Thomson BG, Felgenhauer JL, Holcenberg JS, Panosyan EH, Avramis VI
Asparaginase pharmacokinetics after intensive polyethylene glycol-conjugated L-asparaginase therapy for children with relapsed acute lymphoblastic leukemia.
15328169 Clinical cancer research : an official journal of the American Association for Cancer Research, 2004 Aug. 15 : 5335-41

McCune JS, Friedman DL, Schuetze S, Blough D, Magbulos M, Hawkins DS
Influence of age upon Ifosfamide-induced nephrotoxicity.
15049014 Pediatric blood & cancer, 2004 May : 42(5)427-32

Bradfield SM, Douglas JG, Hawkins DS, Sanders JE, Park JR
Fractionated low-dose radiotherapy after myeloablative stem cell transplantation for local control in patients with high-risk neuroblastoma.
15022296 Cancer, 2004 March 15 : 100(6)1268-75

Finn LS, Hawkins DS, Rutledge JC, Patterson K
Evaluation of early marrow response in childhood aneuploid acute lymphoblastic leukemia: flow cytometric DNA analysis versus standard morphology.
15255034 Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, 2004 Jan. : 7(1)39-47

Hawkins DS, Arndt CA
Pattern of disease recurrence and prognostic factors in patients with osteosarcoma treated with contemporary chemotherapy.
14635080 Cancer, 2003 Dec. 1 : 98(11)2447-56

Smith SC, Lindsley SK, Felgenhauer J, Hawkins DS, Douglas JG
Intensive induction chemotherapy and delayed irradiation in the management of parameningeal rhabdomyosarcoma.
14528099 Journal of pediatric hematology/oncology, 2003 Oct. : 25(10)774-9

Wright JA, Bradfield SM, Park JR, Hawkins DS
Prolonged survival after invasive aspergillosis: a single-institution review of 11 cases.
12679641 Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology, 2003 April : 286-91

Park JR, Coughlin J, Hawkins D, Friedman DL, Burns JL, Pendergrass T
Ciprofloxacin and amoxicillin as continuation treatment of febrile neutropenia in pediatric cancer patients.
12461792 Medical and pediatric oncology, 2003 Feb. : 40(2)93-8

Hawkins DS, Felgenhauer J, Park J, Kreissman S, Thomson B, Douglas J, Rowley SD, Gooley T, Sanders JE, Pendergrass TW
Peripheral blood stem cell support reduces the toxicity of intensive chemotherapy for children and adolescents with metastatic sarcomas.
12216105 Cancer, 2002 Sept. 15 : 1354-65

Mansky PJ, Liewehr DJ, Steinberg SM, Chrousos GP, Avila NA, Long L, Bernstein D, Mackall CL, Hawkins DS, Helman LJ
Treatment of metastatic osteosarcoma with the somatostatin analog OncoLar: significant reduction of insulin-like growth factor-1 serum levels.
12218590 Journal of pediatric hematology/oncology, 2002 Aug. : 24(6)440-6

Hawkins DS, Rajendran JG, Conrad EU 3rd, Bruckner JD, Eary JF
Evaluation of chemotherapy response in pediatric bone sarcomas by [F-18]-fluorodeoxy-D-glucose positron emission tomography.
12115361 Cancer, 2002 June 15 : 94(12)3277-84
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Presentations Title	Event	Location	Date
Successes and challenges in pediatric cancer: the Children’s Oncology Group (COG) perspective		Biopathology Center at Nationwide Children’s Hospital, Columbus, OH	2022
Successes and challenges in pediatric cancer: the Children’s Oncology Group (COG) perspective	American Medical School Pediatric Department Chair Annual Meeting	Virtual	2022
Update on the medical management of osteosarcoma	2021 Pakistan Orthopedic Oncology Virtual Conference	Virtual	2021
Evolution of risk stratification of rhabdomyosarcoma and its role in management	Pakistan Society of Pediatric Oncology Symposium	Virtual	2021
Pediatric early phase drug development: the world is wide enough for POETIC and COG	Pediatric Oncology Experimental Therapeutics Investigator’s Consortium (POETIC) Fall 2021 Meeting	Virtual	2021
NCI Molecular Characterization Protocol and Project:EveryChild approach	National Cancer Institute Childhood Cancer Data Initiative Annual Symposium	Virtual	2021
Current and future NCI-COG strategies for precision medicine in pediatric rhabdomyosarcoma	Summer’s Way Rhabdomyosarcoma Workshop	Virtual	2021
Biology and treatment of rhabdomyosarcoma: lessons from the Children's Oncology Group	Norton Children’s Hospital Pediatric Grand Rounds	Virtual	2021
Successes and challenges in pediatric cancer: the Children’s Oncology Group (COG) perspective	Evan Dunbar Lectureship	Louisville, KY	2021
Successes and challenges in pediatric cancer: the Children’s Oncology Group (COG) perspective	Australian and New Zealand Children’s Haematology/Oncology Group (ANZCHOG) Annual Scientific Meeting	Virtual	2021
COG perspective on the impact of COVID-19 on pediatric oncology clinical trials and implications for the future	American Society of Clinical Oncology Annual Meeting	Virtual	2021
Informing pediatric clinical research strategies and drug development through RWE	Food and Drug Administration, Center for Drug Evaluation and Research, Pediatric Oncology Subcommittee of the Oncologic Drugs Advisory Committee Meeting	Virtual	2021
Incorporating Pediatric PRO-CTCAE in NCTN clinical trials	Food and Drug Administration, Center for Drug Evaluation and Research, Pediatric Oncology Subcommittee of the Oncologic Drugs Advisory Committee Meeting	Virtual	2021
Successes and challenges in pediatric cancer: the Children’s Oncology Group (COG) perspective	Science of Childhood Cancer, St. Jude Cancer Research Hospital	Virtual	2021
Successes and challenges in pediatric cancer: the Children’s Oncology Group (COG) perspective	University of Iowa Stead Family Department of Pediatric Grand Rounds	Virtual	2021
Children’s Oncology Group strategies for treatment of rhabdomyosarcoma	5th Pediatric Hematology & Oncology Updates	King Faisal Specialist Hospital & Research Center, Saudi Arabia,Saudi Arabia (virtual)	2020
Perspectives from the new COG Group Chair	Coalition Against Childhood Cancer 8th Annual Summit	On-line	2020
The past, present, and future of maintenance chemotherapy in rhabdomyosarcoma	2020 Pediatric Soft Tissue Sarcoma Conference	Houston, TX	2020
Children’s Oncology Group Soft Tissue Sarcoma Committee update to EpSSG	European Paediatric Soft Tissue Sarcoma Meeting	London, United Kingdom	2019
Multidisciplinary management of parameningeal rhabdomyosarcoma: point of view of the pediatrician	International Society of Paediatric Oncology	Lyon, France	2019
Lessons from the COG Soft Tissue Sarcoma Committee for international collaboration	European Society for Paediatric Oncology	Prague, Czech Republic	2019
DICER1 Mutations in Sarcomas	European Society for Paediatric Oncology	Prague, Czech Republic	2019
Children’s Oncology Group Strategies for Ewing sarcoma treatment	Grupo de America Latina de Oncologia Pediatrica	Buenos Aires, Argentina	2019
2019 update from Children’s Oncology Group Soft Tissue Sarcoma Committee	American Society of Pediatric Hematology/Oncology	New Orleans, LA	2019
Chemotherapy for rhabdomyosarcoma: the Children’s Oncology Group perspective	West Coast Sarcoma Conference	Vancouver, British Columbia	2019
Clinical trials past, present, and future for rhabdomyosarcoma: the Children’s Oncology Group perspective	Ruth Rappaport Annual Meeting in Pediatric Oncology, Northern Israel	Haifa, Israel	2019
Clinical trials past, present, and future for rhabdomyosarcoma: the Children’s Oncology Group perspective	Japanese Society of Pediatric Hematology/Oncology	Kyoto, Japan	2018
Discussant, Plenary Session	American Society of Clinical Oncology	Chicago, IL	2018
The Past and Present State of Treatment for Rhabdomyosarcoma: the COG perspective	Summer’s Way Rhabdomyosarcoma Workshop	Denver, CO	2018
Children’s Oncology Group Update on Soft Tissue Sarcoma Clinical Trials	European Paediatric Soft Tissue Sarcoma Meeting	Lyon, France	2017
Lessons Learned in the Search of New Treatment for Pediatric Sarcomas	New Horizons in Young Adult Oncology Symposium	Cincinnati, Ohio	2017
Children’s Oncology Group Update on Soft Tissue Sarcoma Clinical Trials	European Paediatric Soft Tissue Sarcoma Meeting	Copenhagen, Denmark	2017
Biology and Treatment of Rhabdomyosarcoma in the Genomics Age	Hematology/Oncology Grand Rounds, Children’s National Medical Center	Washington, DC	2017
Risk Stratification for Rhabdomyosarcoma in the Modern Era	Cooperative Weichteilsarkom Studiengruppe, European Paediatric Soft Tissue Sarcoma, and Children’s Oncology Group Soft Tissue Sarcoma Meeting	Stuttgart, Germany	2016
Treating Pediatric Soft Tissue Sarcomas in the Genomic and Targeted Therapy Age: the COG Approach	Soft Tissue Sarcoma in the Young: Expectations, Achievements and Perspectives	Stuttgart, Germany	2016
Children’s Oncology Group Update on Soft Tissue Sarcoma Clinical Trials	European Paediatric Soft Tissue Sarcoma Meeting	Barcelona, Spain	2016
Very high risk alveolar rhabdomyosarcoma: comparative analysis of Children’s Oncology Group European Paediatric Soft Tissue Sarcoma studies	European Paediatric Soft Tissue Sarcoma Meeting	Barcelona, Spain	2016
Children’s Oncology Group Update on Soft Tissue Sarcoma Clinical Trials	European Paediatric Soft Tissue Sarcoma Meeting	Amsterdam, The Netherlands	2015
Children’s Oncology Group Update on Soft Tissue Sarcoma Clinical Trials	European Paediatric Soft Tissue Sarcoma Meeting	Sutton, United Kingdom	2015
Children’s Oncology Group: Future Plans and Ongoing Studies in Ewing Sarcoma	Sarkomkonferenz	Münster, Germany	2015
Children’s Oncology Group Update on Soft Tissue Sarcoma Clinical Trials	European Paediatric Soft Tissue Sarcoma Meeting	Lyon, France	2014
Children’s Oncology Group Approach to Treatment of Rhabdomyosarcoma	Pablove Foundation International Think Tank	Los Angeles, CA	2014
Rhabdomyosarcoma: How many and how to treat?	Joseph McBride Memorial Sarcoma Lecture, Inova Comprehensive Cancer & Research Institute	Fairfax, VA	2014
Children’s Oncology Group Update on Soft Tissue Sarcoma Clinical Trials	European Paediatric Soft Tissue Sarcoma Meeting	Milan, Italy	2014
Rhabdomyosarcoma: How many and how to treat?	Grand Rounds, St. Jude Children’s Research Hospital	Memphis, TN	2014
What Children with Rhabdomyosarcoma Have Taught Me	Pediatric Grand Rounds, Alfred I. duPont Hospital for Children	Wilmington, DE	2013 - 2013
COG approach to identification and introduction of new/targeted therapies in RMS/STS	European Paediatric Soft Tissue Sarcoma Meeting	Paris, France,	March 22, 2013
Rhabdomyosarcoma: How many and how to treat	Texas Childrens Cancer Center	Houston, TX	Feb. 14, 2013
What children have taught me about rhabdomyosarcoma	Pediatric Grand Rounds, Childrens Hospital at Montefiore	Bronx, NY	Jan. 30, 2013
From Seattle to Sydney: lessons from selected pediatric sarcoma cases	Pediatric Oncology Conference	Sydney, Australia	Oct. 8, 2012
Childrens Oncology Group update on soft tissue sarcoma clinical trials	International Symposium on the Biology and Treatment of the Pediatric Soft Tissue Sarcomas	Padova, Italy	Dec. 6, 2011

Grant Title	Grantor	Amount	Award Date
COG NCTN Integrated Translational Science Center for Hematopoietic Malignancies in Children	National Cancer Institute		2020 - 2025
COG NCORP Research Base	National Cancer Institute		2020 - 2025
COG NCTN Network Group Operations Center Grant	National Cancer Institute	$119,586,932	2020 - 2025

Overview

Board Certification(s): Pediatric Hematology-Oncology
Medical/Professional School: Harvard Medical School, Boston, MA
Residency: University of Washington School of Medicine, Seattle, WA
Clinical Interests: Sarcomas, clinical trials
Research Description: The goals of the Children's Oncology Group are to: 1) design and conduct collaborative clinical-translational studies for children with cancer that build on an increasing understanding of the molecular basis for pediatric malignancies, bridge gaps in knowledge, and have the highest potential to improve outcome for all childhood cancer patients; 2) conduct research that lessens the morbidity of cancer therapy and improves the quality of life for children throughout their care, spanning diagnosis, treatment and survivorship; 3) collect and highly annotate biospecimens from all children with cancer, leveraging COG’s nearly population based research enterprise, to provide the foundation for discovery of the molecular basis of all childhood cancers, no matter how rare, and accelerate the most promising translational research efforts conducted at laboratories around the world
Research Focus Area: Refractory and recurrent cancer, Sarcomas, Thyroid Cancer, Cancer biology, Cancer

Contact Information

Primary Office

Seattle Children's - Hematology-Oncology 4800 Sand Point Way NE
MB.8.501
Seattle, WA 98105 Tel: 206-987-2106

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