Douglas S Hawkins, MD
Cancer and Blood Disorders Center, Thyroid Program, Bone Tumors and Soft Tissue Tumors, Solid Tumors Oncology
On staff since February 1996
Children's Title: Chair, Children's Oncology Group
Academic Title: Professor, Hematology-Oncology
Research Center: Ben Towne Center for Childhood Cancer Research
"I feel exceptionally fortunate to work with some of the smartest people I know. Each day brings new opportunities to learn from my colleagues, patients and families. By the nature of our work in Hematology/Oncology, we see the importance of what we do every day. I am continually impressed by our ability to change the lives of children and young adults for the better, both with good clinical care and by clinical and translational research efforts. My hope is that the clinical research done by the Children's Oncology Group and at Seattle Children's Hospital today will lead to more effective treatments with fewer side effects for children and young adults in the future."
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Douglas S. Hawkins, MD, is the Group Chair of the Children's Oncology Group (COG). COG is the world’s largest organization devoted exclusively to childhood and adolescent cancer research. COG unites over 10,000 experts in childhood cancer at more than 200 leading children’s hospitals, universities, and cancer centers across North America, Australia, and New Zealand in the fight against childhood cancer. Dr. Hawkins is a clinician at Seattle Children's Hospital and Professor of Pediatrics at the University of Washington School of Medicine.
Dr. Hawkins is Group Chair of the Children's Oncology Group (COG). Prior to becoming COG Group Chair in 2020, he was the Chair of the COG Soft Tissue Sarcoma Committee, overseeing the conduct of biology studies and clinical trials for rhabdomyosarcoma and other soft tissue sarcomas across North America. Dr. Hawkins was a member of the COG Bone Tumor Steering Committee. His academic career has focused on clinical research, particularly in the treatment of pediatric sarcomas. He was the chair of two COG clinical trials, one for Ewing sarcoma and another for rhabdomyosarcoma. He chairs the international EURO EWING Consortium External Advisory Board, and also chairs the international Frontline and Relapse in RhabdoMyoSarcoma Study (FaR-RMS) Data Monitoring Committee.
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Our sons life was saved by Dr. Hawkins and his incredible team. From the confusion and shock of the initial diagnosis to end of treatment celebration, Dr. Hawkins not only walked by our son's side every step of the way, he personally invested in our entire family. Dr. Hawkins is equal parts honest, courageous, brilliant, and compassionate. Dr. Hawkins and his team are an inspiration, and our family is eternally grateful for all that they do!
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Dr. Hawkins is a professional, kind and caring doctor with a large expertise in treating childhood cancer. Upon our orientation at Children's, he was the key person that explained the medicines, treatment plan, schedule and expectations. He explained differences in treatment plans in Europe and North America. He presented our scans, biopsy and test results making sure that we understood everything. He has done a good job and our son is now cured of cancer. Thank you Dr. Hawkins and the expert staff at Seattle Children's!
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Dr. Hawkins and his incredible team saved out daughters life. Dr. Hawkins had the insight to look past the original diagnosis given to our daughter. She was diagnosed with TEC at 15 months with a HCT of 7. This was not life sustaining. He and his team consulted, worked, planned and communitcated with each other and our family to come up with the best course of treatment. I cant thank Dr. Hawkins and Seattle Children's enough. They preform miracles everyday!
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Dr. Hawkins works around the clock to give our children the best care. I am happy to say my son is a bone cancer survivor. I appreciated how Dr. Hawkins worked to make sure the side affects from the chemo where addressed as well as its progress. Thank you so much, Janice B.
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Dr. Hawkins saved my daughters life,who was diagnosed with stage 4 alveolar rhabdomyosarcoma last year.My daughter is cancer free for almost three months now because of Dr. Hawkins and his team.God bless them.God is Good.
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I was a distraught parent when my daughter was diagnosed at 15 with Hodgkin's lymphoma. he spent the time to make me feel at ease and encouraged me to participate in her care . i didn't have a clue what i should do . he made me feel comfortable to ask a lot of questions, and he answered with reassurance and calmness . He worked closely with me as a parent as well as his colleagues to give her the best care she could get. he responded as quickly as possible to all of my phone calls. He is a very humble man for all of his qualifications . there are a lot of people who look up to him , if he only knew how many .... many thanks!! we pray for his continued success!!
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Five years ago, my 8 1/2 year old son was diagnosed with Hodgkin's Lymphoma. I remember Dr Hawkins looking me right in the eye and saying, "This cancer is very, very, VERY curable." I clung to his words, and today we are celebrating my son's 14th birthday. Thank you Dr. Hawkins, and Children's, for assisting God in our son's healing!
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Five years ago, my 8 1/2 year old son was diagnosed with Hodgkin's Lymphoma. I remember Dr Hawkins looking me right in the eye and saying, "This cancer is very, very, VERY curable." I clung to his words, and today we are celebrating my son's 14th birthday. Thank you Dr. Hawkins, and Children's, for assisting God in our son's healing!
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If you are seeing Dr. Hawkins, you've likely heard the worst thing you will ever hear: your child has cancer. If that's the case, thank God you're seeing Dr. Hawkins! My son nearly died before he was diagnosed in 1997 at age 2 with Burkitt's Lymphoma. We were so grateful to have Dr. Hawkins on his team. He's honest, clear, compassionate and simply the most knowledgeable physician treating kids today. My son is 16 now, rowing crew and making the honor roll!
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Dr. Hawkins is my personal Hero! I was two weeks short of dying when he took over. I had stage 4 hodgkins lymphoma I was 15 yrs old. I am now 20 and I have a beautiful son and have been in remisson for 5 yrs now. Thank you Dr. Hawkins!
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Dr. Doug Hawkins and Dr. Lawrence Cooper diagnosed our son Eric as a Lg Cell Lymphoma patient in early 1997 when he was 10. Eric recently had his 24th Birthday, THANKS TO THEIR KNOWLEDGE AND CARE. He is a SURVIVOR!! Thank you to them and all the wonderful nurses that made that hard time bearable. Sincerely, Eric's Mom & Dad
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Award Name Award Description Awarded By Award Date SEATTLE TOP DOCTOR - 2012 to 2022 Seattle Magazine 2022 Seattle's Top Doctor 2020 Seattle Met 2020 Seattle's Top Doctor 2016 Seattle Met Magazine 2016 Seattle's Top Doctor 2013 Seattle Met Magazine 2013 U.S. News Top Doctor U.S. News and World Report 2012 Newsweek Health: Top Cancer Doctors 2015 Newsweek 2015 -
Other Publications
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Eckstein OS, Allen CE, Williams PM, Roy-Chowdhuri S, Patton DR, Coffey B, Reid JM, Piao J, Saguilig L, Alonzo TA, Berg SL, Ramirez NC, Jaju A, Mhlanga J, Fox E, Hawkins DS, Mooney MM, Takebe N, Tricoli JV, Janeway KA, Seibel NL, Parsons DWPhase II Study of Selumetinib in Children and Young Adults With Tumors Harboring Activating Mitogen-Activated Protein Kinase Pathway Genetic Alterations: Arm E of the NCI-COG Pediatric MATCH Trial.
35363510 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022 Apr 1 : JCO2102840 -
Haduong JH, Heske CM, Allen-Rhoades W, Xue W, Teot LA, Rodeberg DA, Donaldson SS, Weiss A, Hawkins DS, Venkatramani RAn update on rhabdomyosarcoma risk stratification and the rationale for current and future Children's Oncology Group clinical trials.
35129294 Pediatric blood & cancer, 2022 April : 69(4)e29511 PMCID:PMC8976559 -
Parsons DW, Janeway KA, Patton DR, Winter CL, Coffey B, Williams PM, Roy-Chowdhuri S, Tsongalis GJ, Routbort M, Ramirez NC, Saguilig L, Piao J, Alonzo TA, Berg SL, Fox E, Hawkins DS, Abrams JS, Mooney M, Takebe N, Tricoli JV, Seibel NL, NCI-COG Pediatric MATCH Team.Actionable Tumor Alterations and Treatment Protocol Enrollment of Pediatric and Young Adult Patients With Refractory Cancers in the National Cancer Institute-Children's Oncology Group Pediatric MATCH Trial.
35353553 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022 Mar 30 : JCO2102838 -
Crane JN, Xue W, Qumseya A, Gao Z, Arndt CAS, Donaldson SS, Harrison DJ, Hawkins DS, Linardic CM, Mascarenhas L, Meyer WH, Rodeberg DA, Rudzinski ER, Shulkin BL, Walterhouse DO, Venkatramani R, Weiss ARClinical group and modified TNM stage for rhabdomyosarcoma: A review from the Children's Oncology Group.
35253352 Pediatric blood & cancer, 2022 Mar 6 : e29644 -
Fetzko S, Fonseca A, Frances Wedekind M, Gupta AA, Setty BA, Schraw J, Lupo PJ, Guillerman RP, Butala AA, Russell H, Nicholls L, Walterhouse D, Hawkins DS, Okcu MFIs Detection of Relapse by Surveillance Imaging Associated With Longer Survival in Patients With Rhabdomyosarcoma?
35137727 Journal of pediatric hematology/oncology, 2022 Feb 9 -
Russell HV, Chi YY, Okcu MF, Bernhardt MB, Rodriguez-Galindo C, Gupta AA, Hawkins DSRising drug cost impacts on cost-effectiveness of 2 chemotherapy regimens for intermediate-risk rhabdomyosarcoma: A report from the Children's Oncology Group.
34623638 Cancer, 2022 Jan 15 : 128(2)317-325 PMCID:PMC8738099 -
Pearson AD, Rossig C, Mackall C, Shah NN, Baruchel A, Reaman G, Ricafort R, Heenen D, Bassan A, Berntgen M, Bird N, Bleickardt E, Bouchkouj N, Bross P, Brownstein C, Cohen SB, de Rojas T, Ehrlich L, Fox E, Gottschalk S, Hanssens L, Hawkins DS, Horak ID, Taylor DH, Johnson C, Karres D, Ligas F, Ludwinski D, Mamonkin M, Marshall L, Masouleh BK, Matloub Y, Maude S, McDonough J, Minard-Colin V, Norga K, Nysom K, Pappo A, Pearce L, Pieters R, Pule M, Quintás-Cardama A, Richardson N, Schüßler-Lenz M, Scobie N, Sersch MA, Smith MA, Sterba J, Tasian SK, Weigel B, Weiner SL, Zwaan CM, Lesa G, Vassal GPaediatric Strategy Forum for medicinal product development of chimeric antigen receptor T-cells in children and adolescents with cancer: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
34840026 European journal of cancer (Oxford, England : 1990), 2022 Jan. : 160112-133 -
Leavey PJ, Laack NN, Krailo MD, Buxton A, Randall RL, DuBois SG, Reed DR, Grier HE, Hawkins DS, Pawel B, Nadel H, Womer RB, Letson GD, Bernstein M, Brown K, Maciej A, Chuba P, Ahmed AA, Indelicato DJ, Wang D, Marina N, Gorlick R, Janeway KA, Mascarenhas LPhase III Trial Adding Vincristine-Topotecan-Cyclophosphamide to the Initial Treatment of Patients With Nonmetastatic Ewing Sarcoma: A Children's Oncology Group Report.
34652968 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021 Dec 20 : 39(36)4029-4038 PMCID:PMC8677904 -
Collier AB 3rd, Krailo MD, Dang HM, DuBois SG, Hawkins DS, Bernstein ML, Bomgaars LR, Reed DR, Gorlick RG, Janeway KAOutcome of patients with relapsed or progressive Ewing sarcoma enrolled on cooperative group phase 2 clinical trials: A report from the Children's Oncology Group.
34496122 Pediatric blood & cancer, 2021 Dec. : 68(12)e29333 PMCID:PMC8541905 -
Pinto N, Navarro SL, Rimorin C, Wurscher M, Hawkins DS, McCune JSPharmacogenomic associations of cyclophosphamide pharmacokinetic candidate genes with event-free survival in intermediate-risk rhabdomyosarcoma: A report from the Children's Oncology Group.
34245211 Pediatric blood & cancer, 2021 Nov. : 68(11)e29203 PMCID:PMC8719493 -
Brady C, Manning SC, Rudzinski E, Paulson V, Wang X, Liu YJ, Parikh SR, Bonilla-Velez J, Hawkins DS, Dahl JClinical Outcomes of Diffuse Sclerosing Variant Papillary Thyroid Carcinoma in Pediatric Patients.
34713899 The Laryngoscope, 2021 Oct 29 -
Shern JF, Selfe J, Izquierdo E, Patidar R, Chou HC, Song YK, Yohe ME, Sindiri S, Wei J, Wen X, Rudzinski ER, Barkauskas DA, Lo T, Hall D, Linardic CM, Hughes D, Jamal S, Jenney M, Chisholm J, Brown R, Jones K, Hicks B, Angelini P, George S, Chesler L, Hubank M, Kelsey A, Gatz SA, Skapek SX, Hawkins DS, Shipley JM, Khan JGenomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium.
34166060 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2021 Sep 10 : 39(26)2859-2871 PMCID:PMC8425837 -
Avutu V, Weiss AR, Reed DR, Ahmed SK, Allen-Rhoades WA, Chen YE, Davis LE, Eaton BR, Hawkins DS, Indelicato DJ, Patel SR, Randall RL, Reinke DK, Riedel RF, Scharschmidt TJ, Thornton KA, Wang D, Janeway KA, Kopp LMIdentified Enrollment Challenges of Adolescent and Young Adult Patients on the Nonchemotherapy Arm of Children's Oncology Group Study ARST1321.
34515544 Journal of adolescent and young adult oncology, 2021 Sep 9 -
Million L, Hayes-Jordan A, Chi YY, Donaldson SS, Wolden S, Morris C, Terezakis S, Laurie F, Morano K, Fitzgerald TJ, Yock TI, Rodeberg DA, Anderson JR, Speights RA, Black JO, Coffin C, McCarville MB, Kao SC, Hawkins DS, Spunt SL, Randall RLLocal Control For High-Grade Nonrhabdomyosarcoma Soft Tissue Sarcoma Assigned to Radiation Therapy on ARST0332: A Report From the Childrens Oncology Group.
33548339 International journal of radiation oncology, biology, physics, 2021 Jul 1 : 110(3)821-830 PMCID:PMC8767764 -
Li H, Sisoudiya SD, Martin-Giacalone BA, Khayat MM, Dugan-Perez S, Marquez-Do DA, Scheurer ME, Muzny D, Boerwinkle E, Gibbs RA, Chi YY, Barkauskas DA, Lo T, Hall D, Stewart DR, Schiffman JD, Skapek SX, Hawkins DS, Plon SE, Sabo A, Lupo PJGermline Cancer Predisposition Variants in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group.
33372952 Journal of the National Cancer Institute, 2021 Jul 1 : 113(7)875-883 PMCID:PMC8246828 -
Kohli K, Yao L, Nowicki TS, Zhang S, Black RG, Schroeder BA, Farrar EA, Cao J, Sloan H, Stief D, Cranmer LD, Wagner MJ, Hawkins DS, Pillarisetty VG, Ribas A, Campbell J, Pierce RH, Kim EY, Jones RL, Riddell SR, Yee C, Pollack SMIL-15 mediated expansion of rare durable memory T cells following adoptive cellular therapy.
33963013 Journal for immunotherapy of cancer, 2021 May : 9(5) PMCID:PMC8108691 -
Chugh R, Ballman KV, Helman LJ, Patel S, Whelan JS, Widemann B, Lu Y, Hawkins DS, Mascarenhas L, Glod JW, Ji J, Zhang Y, Reinke D, Strauss SJSARC025 arms 1 and 2: A phase 1 study of the poly(ADP-ribose) polymerase inhibitor niraparib with temozolomide or irinotecan in patients with advanced Ewing sarcoma.
33289920 Cancer, 2021 Apr 15 : 127(8)1301-1310 PMCID:PMC8246769 -
Pacenta HL, Allen-Rhoades W, Langenau D, Houghton PJ, Keller C, Heske CM, Deel MD, Linardic CM, Shern JF, Stewart E, Turpin B, Harrison DJ, Khan J, Mascarenhas L, Skapek SX, Meyer WH, Hawkins DS, Chen EY, Amatruda JF, Hingorani P, Laetsch TWPrioritization of Novel Agents for Patients with Rhabdomyosarcoma: A Report from the Children's Oncology Group (COG) New Agents for Rhabdomyosarcoma Task Force.
33915882 Journal of clinical medicine, 2021 Apr 1 : 10(7) PMCID:PMC8037615 -
Rogers TN, Seitz G, Fuchs J, Martelli H, Dasgupta R, Routh JC, Hawkins DS, Koscielniak E, Bisogno G, Rodeberg DASurgical management of paratesticular rhabdomyosarcoma: A consensus opinion from the Children's Oncology Group, European paediatric Soft tissue sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe.
33522706 Pediatric blood & cancer, 2021 April : 68(4)e28938 -
Heske CM, Chi YY, Venkatramani R, Li M, Arnold MA, Dasgupta R, Hiniker SM, Hawkins DS, Mascarenhas LSurvival outcomes of patients with localized FOXO1 fusion-positive rhabdomyosarcoma treated on recent clinical trials: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.
33216382 Cancer, 2021 Mar 15 : 127(6)946-956 PMCID:PMC8601034 -
Gallego S, Chi YY, De Salvo GL, Li M, Merks JHM, Rodeberg DA, van Scheltinga ST, Mascarenhas L, Orbach D, Jenney M, Million L, Minard-Colin V, Wolden S, Zanetti I, Parham DM, Mandeville H, Venkatramani R, Bisogno G, Hawkins DS, European paediatric Soft tissue sarcoma Study Group and Children's Oncology Group.Alveolar rhabdomyosarcoma with regional nodal involvement: Results of a combined analysis from two cooperative groups.
33245207 Pediatric blood & cancer, 2021 March : 68(3)e28832 PMCID:PMC8414760 -
Moreira DC, Millen GC, Sands S, Kearns PR, Hawkins DSThe Care of Children With Cancer During the COVID-19 Pandemic.
33989020 American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 2021 March : 411-10 -
Rudzinski ER, Kelsey A, Vokuhl C, Linardic CM, Shipley J, Hettmer S, Koscielniak E, Hawkins DS, Bisogno GPathology of childhood rhabdomyosarcoma: A consensus opinion document from the Children's Oncology Group, European Paediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe.
33306276 Pediatric blood & cancer, 2021 March : 68(3)e28798 -
Harrison DJ, Chi YY, Tian J, Hingorani P, Mascarenhas L, McCowage GB, Weigel BJ, Venkatramani R, Wolden SL, Yock TI, Rodeberg DA, Hayes-Jordan AA, Teot LA, Spunt SL, Meyer WH, Hawkins DS, Shulkin BL, Parisi MTMetabolic response as assessed by 18 F-fluorodeoxyglucose positron emission tomography-computed tomography does not predict outcome in patients with intermediate- or high-risk rhabdomyosarcoma: A report from the Children's Oncology Group Soft Tissue Sarcoma Committee.
33340280 Cancer medicine, 2021 Feb. : 10(3)857-866 PMCID:PMC7897958 -
Lautz TB, Chi YY, Li M, Wolden SL, Casey DL, Routh JC, Granberg CF, Binite O, Rudzinski ER, Hawkins DS, Venkatramani R, Rodeberg DABenefit of delayed primary excision in rhabdomyosarcoma: A report from the Children's Oncology Group.
33079399 Cancer, 2021 Jan 15 : 127(2)275-283 PMCID:PMC7790947 -
Kim J, Light N, Subasri V, Young EL, Wegman-Ostrosky T, Barkauskas DA, Hall D, Lupo PJ, Patidar R, Maese LD, Jones K, Wang M, Tavtigian SV, Wu D, Shlien A, Telfer F, Goldenberg A, Skapek SX, Wei JS, Wen X, Catchpoole D, Hawkins DS, Schiffman JD, Khan J, Malkin D, Stewart DRPathogenic Germline Variants in Cancer Susceptibility Genes in Children and Young Adults With Rhabdomyosarcoma.
34095712 JCO precision oncology, 2021 : 5 PMCID:PMC8169077 -
Shenoy A, Alvarez E, Chi YY, Li M, Shern JF, Khan J, Hiniker SM, Granberg CF, Hawkins DS, Parham DM, Teot LA, Rudzinski ERThe prognostic significance of anaplasia in childhood rhabdomyosarcoma: A report from the Children's Oncology Group.
33302115 European journal of cancer (Oxford, England : 1990), 2021 Jan. : 143127-133 PMCID:PMC8842073 -
Bertagnolli MM, Blanke CD, Curran WJ, Hawkins DS, Mannel RS, O'Dwyer PJ, Schnall MD, Wolmark NWhat happened to the US cancer cooperative groups? A status update ten years after the Institute of Medicine report.
32970346 Cancer, 2020 Dec 1 : 126(23)5022-5029 PMCID:PMC7667615 -
Hawkins DS, Bisogno G, Koscielniak EIntroducing INSTRuCT: An international effort to promote cooperation and data sharing.
32918788 Pediatric blood & cancer, 2020 Sep 12 : e28701 -
Orbach D, Sparber-Sauer M, Laetsch TW, Minard-Colin V, Bielack SS, Casanova M, Corradini N, Koscielniak E, Scheer M, Hettmer S, Bisogno G, Hawkins DS, Ferrari ASpotlight on the treatment of infantile fibrosarcoma in the era of neurotrophic tropomyosin receptor kinase inhibitors: International consensus and remaining controversies.
32784118 European journal of cancer (Oxford, England : 1990), 2020 Aug 9 : 137183-192 -
Morris CD, Tunn PU, Rodeberg DA, Terwisscha van Scheltinga S, Binitie O, Godzinski J, Dall'Igna P, Million L, Hawkins DS, Koscielniak E, Bisogno G, Rogers TNSurgical management of extremity rhabdomyosarcoma: A consensus opinion from the Children's Oncology Group, the European Pediatric Soft-Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe.
32776456 Pediatric blood & cancer, 2020 Aug 9 : e28608 -
Lautz TB, Martelli H, Fuchs J, Chargari C, Smeulders N, Granberg CF, Wolden SL, Sparber-Sauer M, Hawkins DS, Bisogno G, Koscielniak E, Rodeberg DA, Seitz G, INSTRuCT group.Local treatment of rhabdomyosarcoma of the female genital tract: Expert consensus from the Children's Oncology Group, the European Soft-Tissue Sarcoma Group, and the Cooperative Weichteilsarkom Studiengruppe.
32762004 Pediatric blood & cancer, 2020 Aug 6 : e28601 -
Weiss AR, Chen YL, Scharschmidt TJ, Chi YY, Tian J, Black JO, Davis JL, Fanburg-Smith JC, Zambrano E, Anderson J, Arens R, Binitie O, Choy E, Davis JW, Hayes-Jordan A, Kao SC, Kayton ML, Kessel S, Lim R, Meyer WH, Million L, Okuno SH, Ostrenga A, Parisi MT, Pryma DA, Randall RL, Rosen MA, Schlapkohl M, Shulkin BL, Smith EA, Sorger JI, Terezakis S, Hawkins DS, Spunt SL, Wang DPathological response in children and adults with large unresected intermediate-grade or high-grade soft tissue sarcoma receiving preoperative chemoradiotherapy with or without pazopanib (ARST1321): a multicentre, randomised, open-label, phase 2 trial.
32702309 The Lancet. Oncology, 2020 Aug. : 21(8)1110-1122 -
Hingorani P, Dinu V, Zhang X, Lei H, Shern JF, Park J, Steel J, Rauf F, Parham D, Gastier-Foster J, Hall D, Hawkins DS, Skapek SX, Labaer J, McEachron TATranscriptome analysis of desmoplastic small round cell tumors identifies actionable therapeutic targets: a report from the Children's Oncology Group.
32703985 Scientific reports, 2020 Jul 23 : 10(1)12318 PMCID:PMC7378211 -
Schultz L, Link MP, Rheingold S, Hawkins DS, Dome JS, Wickiser J, Kung AL, Henderson TO, Aftandilian CSummary of COVID-19 clinical practice adjustments across select institutions.
32779834 Pediatric blood & cancer, 2020 Jul 19 : e28411 -
Kazahaya K, Prickett KK, Paulson VA, Dahl JP, Manning SC, Rudzinski ER, Rastatter JC, Parikh SR, Hawkins DS, Brose MS, Bauer AJTargeted Oncogene Therapy Before Surgery in Pediatric Patients With Advanced Invasive Thyroid Cancer at Initial Presentation: Is It Time for a Paradigm Shift?
32614439 JAMA otolaryngology-- head & neck surgery, 2020 Jul 2 -
Sullivan M, Bouffet E, Rodriguez-Galindo C, Luna-Fineman S, Khan MS, Kearns P, Hawkins DS, Challinor J, Morrissey L, Fuchs J, Marcus K, Balduzzi A, Basset-Salom L, Caniza M, Baker JN, Kebudi R, Hessissen L, Sullivan R, Pritchard-Jones KThe COVID-19 pandemic: A rapid global response for children with cancer from SIOP, COG, SIOP-E, SIOP-PODC, IPSO, PROS, CCI, and St Jude Global.
32400924 Pediatric blood & cancer, 2020 July : 67(7)e28409 PMCID:PMC7235469 -
Routh JC, Dasgupta R, Chi YY, Shnorhavorian M, Tian J, Walterhouse DO, Breneman J, Wolden SL, Arndt CA, Hawkins DS, Rodeberg DAImpact of Local Control and Surgical Lymph Node Evaluation in Localized Paratesticular Rhabdomyosarcoma: A Report from the Children's Oncology Group Soft Tissue Sarcoma Committee.
32525556 International journal of cancer, 2020 Jun 11 -
Prasad PK, Mahajan P, Hawkins DS, Mostoufi-Moab S, Venkatramani RManagement of pediatric differentiated thyroid cancer: An overview for the pediatric oncologist.
32275118 Pediatric blood & cancer, 2020 June : 67(6)e28141 -
Bisogno G, Hawkins DSAn unresolved issue in rhabdomyosarcoma treatment: The duration of chemotherapy.
31994316 Pediatric blood & cancer, 2020 May : 67(5)e28174 -
Aye JM, Chi YY, Tian J, Rudzinski ER, Binitie OT, Dasgupta R, Wolden SL, Hawkins DS, Gupta AADo children and adolescents with completely resected alveolar rhabdomyosarcoma require adjuvant radiation? A report from the Children's Oncology Group.
32124549 Pediatric blood & cancer, 2020 May : 67(5)e28243 -
Lautz TB, Chi YY, Tian J, Gupta AA, Wolden SL, Routh JC, Casey DL, Dasgupta R, Hawkins DS, Rodeberg DARelationship between tumor response at therapy completion and prognosis in patients with Group III rhabdomyosarcoma: A report from the Children's Oncology Group.
32012255 International journal of cancer, 2020 Feb 3 -
Spunt SL, Million L, Chi YY, Anderson J, Tian J, Hibbitts E, Coffin C, McCarville MB, Randall RL, Parham DM, Black JO, Kao SC, Hayes-Jordan A, Wolden S, Laurie F, Speights R, Kawashima E, Skapek SX, Meyer W, Pappo AS, Hawkins DSA risk-based treatment strategy for non-rhabdomyosarcoma soft-tissue sarcomas in patients younger than 30 years (ARST0332): a Children's Oncology Group prospective study.
31786124 The Lancet. Oncology, 2020 Jan. : 21(1)145-161 PMCID:PMC6946838 -
Dirksen U, Brennan B, Le Deley MC, Cozic N, van den Berg H, Bhadri V, Brichard B, Claude L, Craft A, Amler S, Gaspar N, Gelderblom H, Goldsby R, Gorlick R, Grier HE, Guinbretiere JM, Hauser P, Hjorth L, Janeway K, Juergens H, Judson I, Krailo M, Kruseova J, Kuehne T, Ladenstein R, Lervat C, Lessnick SL, Lewis I, Linassier C, Marec-Berard P, Marina N, Morland B, Pacquement H, Paulussen M, Randall RL, Ranft A, Le Teuff G, Wheatley K, Whelan J, Womer R, Oberlin O, Hawkins DS, Euro-E.W.I.N.G. 99 and Ewing 2008 Investigators.High-Dose Chemotherapy Compared With Standard Chemotherapy and Lung Radiation in Ewing Sarcoma With Pulmonary Metastases: Results of the European Ewing Tumour Working Initiative of National Groups, 99 Trial and EWING 2008.
31553693 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019 Dec 1 : 37(34)3192-3202 PMCID:PMC6881099 -
Mascarenhas L, Chi YY, Hingorani P, Anderson JR, Lyden ER, Rodeberg DA, Indelicato DJ, Kao SC, Dasgupta R, Spunt SL, Meyer WH, Hawkins DSRandomized Phase II Trial of Bevacizumab or Temsirolimus in Combination With Chemotherapy for First Relapse Rhabdomyosarcoma: A Report From the Children's Oncology Group.
31513481 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019 Nov 1 : 37(31)2866-2874 PMCID:PMC6823886 -
Yohe ME, Heske CM, Stewart E, Adamson PC, Ahmed N, Antonescu CR, Chen E, Collins N, Ehrlich A, Galindo RL, Gryder BE, Hahn H, Hammond S, Hatley ME, Hawkins DS, Hayes MN, Hayes-Jordan A, Helman LJ, Hettmer S, Ignatius MS, Keller C, Khan J, Kirsch DG, Linardic CM, Lupo PJ, Rota R, Shern JF, Shipley J, Sindiri S, Tapscott SJ, Vakoc CR, Wexler LH, Langenau DMInsights into pediatric rhabdomyosarcoma research: Challenges and goals.
31222885 Pediatric blood & cancer, 2019 Oct. : 66(10)e27869 PMCID:PMC6707829 -
Hibbitts E, Chi YY, Hawkins DS, Barr FG, Bradley JA, Dasgupta R, Meyer WH, Rodeberg DA, Rudzinski ER, Spunt SL, Skapek SX, Wolden SL, Arndt CASRefinement of risk stratification for childhood rhabdomyosarcoma using FOXO1 fusion status in addition to established clinical outcome predictors: A report from the Children's Oncology Group.
31456361 Cancer medicine, 2019 Oct. : 8(14)6437-6448 PMCID:PMC6797586 -
Paulson VA, Rudzinski ER, Hawkins DSThyroid Cancer in the Pediatric Population.
31540418 Genes, 2019 Sep 18 : 10(9) PMCID:PMC6771006 -
Casey DL, Chi YY, Donaldson SS, Hawkins DS, Tian J, Arndt CA, Rodeberg DA, Routh JC, Lautz TB, Gupta AA, Yock TI, Wolden SLIncreased local failure for patients with intermediate-risk rhabdomyosarcoma on ARST0531: A report from the Children's Oncology Group.
31174239 Cancer, 2019 Sep 15 : 125(18)3242-3248 PMCID:PMC6717036 -
Mascarenhas L, Lyden ER, Breitfeld PP, Walterhouse DO, Donaldson SS, Rodeberg DA, Parham DM, Anderson JR, Meyer WH, Hawkins DSRisk-based treatment for patients with first relapse or progression of rhabdomyosarcoma: A report from the Children's Oncology Group.
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Shern JF, Chen L, Chmielecki J, Wei JS, Patidar R, Rosenberg M, Ambrogio L, Auclair D, Wang J, Song YK, Tolman C, Hurd L, Liao H, Zhang S, Bogen D, Brohl AS, Sindiri S, Catchpoole D, Badgett T, Getz G, Mora J, Anderson JR, Skapek SX, Barr FG, Meyerson M, Hawkins DS, Khan JComprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors.
24436047 Cancer discovery, 2014 Feb. : 4(2)216-31 -
Russell H, Swint JM, Lal L, Meza J, Walterhouse D, Hawkins DS, Okcu MFCost minimization analysis of two treatment regimens for low-risk rhabdomyosarcoma in children: A report from the Children's Oncology Group.
24453105 Pediatric blood & cancer, 2014 Jan 22 -
Eary JF, Conrad EU, O'Sullivan J, Hawkins DS, Schuetze SM, O'Sullivan FSarcoma mid-therapy [F-18]fluorodeoxyglucose positron emission tomography (FDG PET) and patient outcome.
24430415 The Journal of bone and joint surgery. American volume, 2014 Jan 15 : 96(2)152-8 PMCID:PMC3903137 -
Lupo PJ, Zhou R, Skapek SX, Hawkins DS, Spector LG, Scheurer ME, Fatih Okcu M, Melin B, Papworth K, Erhardt EB, Grufferman SAllergies, atopy, immune-related factors and childhood rhabdomyosarcoma: a report from the Children's Oncology Group.
23824786 International journal of cancer. Journal international du cancer, 2014 Jan 15 : 134(2)431-6 PMCID:PMC3869863 -
Chen X, Stewart E, Shelat AA, Qu C, Bahrami A, Hatley M, Wu G, Bradley C, McEvoy J, Pappo A, Spunt S, Valentine MB, Valentine V, Krafcik F, Lang WH, Wierdl M, Tsurkan L, Tolleman V, Federico SM, Morton C, Lu C, Ding L, Easton J, Rusch M, Nagahawatte P, Wang J, Parker M, Wei L, Hedlund E, Finkelstein D, Edmonson M, Shurtleff S, Boggs K, Mulder H, Yergeau D, Skapek S, Hawkins DS, Ramirez N, Potter PM, Sandoval JA, Davidoff AM, Mardis ER, Wilson RK, Zhang J, Downing JR, Dyer MA, St. Jude Childrens Research HospitalWashington University Pediatric Cancer Genome ProjectTargeting oxidative stress in embryonal rhabdomyosarcoma.
24332040 Cancer cell, 2013 Dec 9 : 24(6)710-24 PMCID:PMC3904731 -
Spalding AC, Hawkins DS, Donaldson SS, Anderson JR, Lyden E, Laurie F, Wolden SL, Arndt CA, Michalski JMThe effect of radiation timing on patients with high-risk features of parameningeal rhabdomyosarcoma: an analysis of IRS-IV and D9803.
24074925 International journal of radiation oncology, biology, physics, 2013 Nov 1 : 87(3)512-6 -
Wilson RA, Teng L, Bachmeyer KM, Bissonnette ML, Husain AN, Parham DM, Triche TJ, Wing MR, Gastier-Foster JM, Barr FG, Hawkins DS, Anderson JR, Skapek SX, Volchenboum SLA novel algorithm for simplification of complex gene classifiers in cancer.
23913937 Cancer research, 2013 Sep 15 : 73(18)5625-32 -
Weiss AR, Lyden ER, Anderson JR, Hawkins DS, Spunt SL, Walterhouse DO, Wolden SL, Parham DM, Rodeberg DA, Kao SC, Womer RBHistologic and clinical characteristics can guide staging evaluations for children and adolescents with rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee.
23940218 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013 Sep 10 : 31(26)3226-32 PMCID:PMC3757291 -
Skapek SX, Anderson J, Barr FG, Bridge JA, Gastier-Foster JM, Parham DM, Rudzinski ER, Triche T, Hawkins DSPAX-FOXO1 fusion status drives unfavorable outcome for children with rhabdomyosarcoma: a children's oncology group report.
23526739 Pediatric blood & cancer, 2013 Sept. : 60(9)1411-7 -
Lupo PJ, Zhou R, Skapek SX, Hawkins DS, Spector LG, Scheurer ME, Fatih Okcu M, Melin B, Papworth K, Erhardt EB, Grufferman SAllergies, atopy, immune-related factors and childhood rhabdomyosarcoma: A report from the children's oncology group.
23824786 International journal of cancer. Journal international du cancer, 2013 Jul 3 -
Skapek SX, Anderson JR, Hill DA, Henry D, Spunt SL, Meyer W, Kao S, Hoffer FA, Grier HE, Hawkins DS, Raney RBSafety and efficacy of high-dose tamoxifen and sulindac for desmoid tumor in children: results of a Children's Oncology Group (COG) phase II study.
23281268 Pediatric blood & cancer, 2013 July : 60(7)1108-12 -
Rudzinski ER, Teot LA, Anderson JR, Moore J, Bridge JA, Barr FG, Gastier-Foster JM, Skapek SX, Hawkins DS, Parham DMDense pattern of embryonal rhabdomyosarcoma, a lesion easily confused with alveolar rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.
23765537 American journal of clinical pathology, 2013 July : 140(1)82-90 -
Skapek SX, Anderson JR, Hill DA, Henry D, Spunt SL, Meyer W, Kao S, Hoffer FA, Grier HE, Hawkins DS, Raney RBSafety and efficacy of high-dose tamoxifen and sulindac for desmoid tumor in children: results of a Children's Oncology Group (COG) phase II study.
23281268 Pediatric blood & cancer, 2013 July : 60(7)1108-12 -
Newman EN, Jones RL, Hawkins DSAn evaluation of [F-18]-fluorodeoxy-D-glucose positron emission tomography, bone scan, and bone marrow aspiration/biopsy as staging investigations in Ewing sarcoma.
23192939 Pediatric blood & cancer, 2013 July : 60(7)1113-7 -
Hawkins DS, Spunt SL, Skapek SX, COG Soft Tissue Sarcoma CommitteeChildren's Oncology Group's 2013 blueprint for research: Soft tissue sarcomas.
23255356 Pediatric blood & cancer, 2013 June : 60(6)1001-8 PMCID:PMC3777409 -
Raney B, Huh W, Hawkins D, Hayes-Jordan A, Million L, Rodeberg D, Teot L, Anderson J, Soft Tissue Sarcoma Committee of the Children's Oncology Group, Arcadia, CAOutcome of patients with localized orbital sarcoma who relapsed following treatment on Intergroup Rhabdomyosarcoma Study Group (IRSG) Protocols-III and -IV, 1984-1997: a report from the Children's Oncology Group.
22961750 Pediatric blood & cancer, 2013 March : 60(3)371-6 -
MacQuarrie KL, Yao Z, Fong AP, Diede SJ, Rudzinski ER, Hawkins DS, Tapscott SJComparison of genome-wide binding of MyoD in normal human myogenic cells and rhabdomyosarcomas identifies regional and local suppression of promyogenic transcription factors.
23230269 Molecular and cellular biology, 2013 Feb. : 33(4)773-84 PMCID:PMC3571334 -
Gardner RA, Thomson B, Hawkins DSSubstitution with doxorubicin for daunorubicin during induction for high risk pediatric acute lymphoblastic leukemia results in increased toxicity.
23015453 Pediatric blood & cancer, 2013 Feb. : 60(2)338-9 -
Soundararajan A, Abraham J, Nelon LD, Prajapati SI, Zarzabal LA, Michalek JE, McHardy SF, Hawkins DS, Malempati S, Keller C18F-FDG microPET imaging detects early transient response to an IGF1R inhibitor in genetically engineered rhabdomyosarcoma models.
22238194 Pediatric blood & cancer, 2012 Sept. : 59(3)485-92 -
Malempati S, Hawkins DSRhabdomyosarcoma: review of the Children's Oncology Group (COG) Soft-Tissue Sarcoma Committee experience and rationale for current COG studies.
22378628 Pediatric blood & cancer, 2012 Jul 15 : 59(1)5-10 -
Rosenberg AR, Skapek SX, Hawkins DSThe inconvenience of convenience cohorts: rhabdomyosarcoma and the PAX-FOXO1 biomarker.
22564868 Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2012 July : 21(7)1012-8 PMCID:PMC3392538 -
Spunt SL, Vargas SO, Coffin CM, Skapek SX, Parham DM, Darling J, Hawkins DS, Keller CThe clinical, research, and social value of autopsy after any cancer death: a perspective from the Children's Oncology Group Soft Tissue Sarcoma Committee.
22006470 Cancer, 2012 Jun 15 : 118(12)3002-9 PMCID:PMC3274663 -
Breneman J, Meza J, Donaldson SS, Raney RB, Wolden S, Michalski J, Laurie F, Rodeberg DA, Meyer W, Walterhouse D, Hawkins DSLocal control with reduced-dose radiotherapy for low-risk rhabdomyosarcoma: a report from the Children's Oncology Group D9602 study.
22104356 International journal of radiation oncology, biology, physics, 2012 Jun 1 : 83(2)720-6 PMCID:PMC3305826 -
Gupta AA, Anderson JR, Pappo AS, Spunt SL, Dasgupta R, Indelicato DJ, Hawkins DSPatterns of chemotherapy-induced toxicities in younger children and adolescents with rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee.
21761400 Cancer, 2012 Feb 15 : 118(4)1130-7 -
Raccor BS, Claessens AJ, Dinh JC, Park JR, Hawkins DS, Thomas SS, Makar KW, McCune JS, Totah RAPotential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo.
21976622 Drug metabolism and disposition: the biological fate of chemicals, 2012 Jan. : 40(1)54-63 PMCID:PMC3250049 -
Hingorani P, Seidel K, Krailo M, Mascarenhas L, Meyers P, Marina N, Conrad EU, Hawkins DSBody mass index (BMI) at diagnosis is associated with surgical wound complications in patients with localized osteosarcoma: a report from the Children's Oncology Group.
21480474 Pediatric blood & cancer, 2011 Dec 1 : 57(6)939-42 PMCID:PMC3135763 -
Hawkins DSSarcomas gone bad: what to do about recurrent Ewing sarcoma.
21681926 Pediatric blood & cancer, 2011 Oct. : 57(4)535-6 -
Stephenson J, Gow KW, Meehan J, Hawkins DS, Avansino JEwing sarcoma/primitive neuroectodermal tumor arising from the adrenal gland in an adolescent.
21681923 Pediatric blood & cancer, 2011 Oct. : 57(4)691-2 -
Malempati S, Rodeberg DA, Donaldson SS, Lyden ER, Anderson JR, Hawkins DS, Arndt CARhabdomyosarcoma in infants younger than 1 year: a report from the Children's Oncology Group.
21264837 Cancer, 2011 Aug 1 : 117(15)3493-501 PMCID:PMC3140625 -
Foster JH, Hawkins DS, Loken MR, Wells DA, Thomson BMinimal residual disease detected prior to hematopoietic cell transplantation.
21370437 Pediatric blood & cancer, 2011 Jul 15 : 57(1)163-5 -
Walterhouse DO, Meza JL, Breneman JC, Donaldson SS, Hayes-Jordan A, Pappo AS, Arndt C, Raney RB, Meyer WH, Hawkins DSLocal control and outcome in children with localized vaginal rhabdomyosarcoma: a report from the Soft Tissue Sarcoma committee of the Children's Oncology Group.
21298768 Pediatric blood & cancer, 2011 Jul 15 : 57(1)76-83 PMCID:PMC3459820 -
La TH, Wolden SL, Rodeberg DA, Hawkins DS, Brown KL, Anderson JR, Donaldson SSRegional nodal involvement and patterns of spread along in-transit pathways in children with rhabdomyosarcoma of the extremity: a report from the Children's Oncology Group.
20542386 International journal of radiation oncology, biology, physics, 2011 Jul 15 : 80(4)1151-7 PMCID:PMC3116031 -
Million L, Anderson J, Breneman J, Hawkins DS, Laurie F, Michalski J, Rodeberg D, Wharam M, Wolden S, Donaldson SS, Soft Tissue Sarcoma Committee of the Children's Oncology GroupInfluence of noncompliance with radiation therapy protocol guidelines and operative bed recurrences for children with rhabdomyosarcoma and microscopic residual disease: a report from the Children's Oncology Group.
20646841 International journal of radiation oncology, biology, physics, 2011 Jun 1 : 80(2)333-8 -
Rodeberg DA, Stoner JA, Garcia-Henriquez N, Randall RL, Spunt SL, Arndt CA, Kao S, Paidas CN, Million L, Hawkins DSTumor volume and patient weight as predictors of outcome in children with intermediate risk rhabdomyosarcoma: a report from the Children's Oncology Group.
24048802 Cancer, 2011 Jun 1 : 117(11)2541-50 PMCID:PMC3117103 -
La TH, Wolden SL, Su Z, Linardic C, Randall RL, Hawkins DS, Donaldson SSLocal therapy for rhabdomyosarcoma of the hands and feet: is amputation necessary? A report from the Children's Oncology Group.
20646853 International journal of radiation oncology, biology, physics, 2011 May 1 : 80(1)206-12 PMCID:PMC3075377 -
Rodeberg DA, Garcia-Henriquez N, Lyden ER, Davicioni E, Parham DM, Skapek SX, Hayes-Jordan AA, Donaldson SS, Brown KL, Triche TJ, Meyer WH, Hawkins DSPrognostic significance and tumor biology of regional lymph node disease in patients with rhabdomyosarcoma: a report from the Children's Oncology Group.
21357792 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011 Apr 1 : 29(10)1304-11 PMCID:PMC3083998 -
Eary JF, Hawkins DS, Rodler ET, Conrad EU 3rd(18)F-FDG PET in sarcoma treatment response imaging.
23133794 American journal of nuclear medicine and molecular imaging, 2011 : 1(1)47-53 PMCID:PMC3477719 -
Rodeberg DA, Stoner JA, Garcia-Henriquez N, Randall RL, Spunt SL, Arndt CA, Kao S, Paidas CN, Million L, Hawkins DSTumor volume and patient weight as predictors of outcome in children with intermediate risk rhabdomyosarcoma: a report from the children's oncology group.
21157950 Cancer, 2010 Dec 14 -
Mascarenhas L, Lyden ER, Breitfeld PP, Walterhouse DO, Donaldson SS, Paidas CN, Parham DM, Anderson JR, Meyer WH, Hawkins DSRandomized phase II window trial of two schedules of irinotecan with vincristine in patients with first relapse or progression of rhabdomyosarcoma: a report from the Children's Oncology Group.
20837952 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010 Oct 20 : 28(30)4658-63 PMCID:PMC2974343 -
Anderson JR, Barr FG, Hawkins DS, Parham DM, Skapek SX, Triche TJFusion-negative alveolar rhabdomyosarcoma: modification of risk stratification is premature.
20697086 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010 Oct 10 : 28(29)e587-8; author reply e589-90 -
Minn AY, Lyden ER, Anderson JR, Million L, Arndt CA, Brown K, Hawkins DS, Donaldson SSEarly treatment failure in intermediate-risk rhabdomyosarcoma: results from IRS-IV and D9803--a report from the Children's Oncology Group.
20713850 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010 Sep 20 : 28(27)4228-32 PMCID:PMC2953975 -
Arndt CA, Koshkina NV, Inwards CY, Hawkins DS, Krailo MD, Villaluna D, Anderson PM, Goorin AM, Blakely ML, Bernstein M, Bell SA, Ray K, Grendahl DC, Marina N, Kleinerman ESInhaled granulocyte-macrophage colony stimulating factor for first pulmonary recurrence of osteosarcoma: effects on disease-free survival and immunomodulation. a report from the Children's Oncology Group.
20576718 Clinical cancer research : an official journal of the American Association for Cancer Research, 2010 Aug 1 : 16(15)4024-30 PMCID:PMC2989183 -
Koschmann C, Thomson B, Hawkins DSNo evidence of a trial effect in newly diagnosed pediatric acute lymphoblastic leukemia.
20194252 Archives of pediatrics & adolescent medicine, 2010 March : 214-7 -
Schmale GA, Hawkins DS, Rutledge J, Conrad EUMalignant progression in two children with multiple osteochondromas.
20467466 Sarcoma, 2010 : 2010417105 PMCID:PMC2866243 -
Fox E, Widemann BC, Hawkins DS, Jayaprakash N, Dagher R, Aikin AA, Bernstein D, Long L, Mackall C, Helman L, Steinberg SM, Balis FMRandomized trial and pharmacokinetic study of pegfilgrastim versus filgrastim after dose-intensive chemotherapy in young adults and children with sarcomas.
19920107 Clinical cancer research : an official journal of the American Association for Cancer Research, 2009 Dec 1 : 15(23)7361-7 PMCID:PMC2787766 -
Arndt CA, Stoner JA, Hawkins DS, Rodeberg DA, Hayes-Jordan AA, Paidas CN, Parham DM, Teot LA, Wharam MD, Breneman JC, Donaldson SS, Anderson JR, Meyer WHVincristine, actinomycin, and cyclophosphamide compared with vincristine, actinomycin, and cyclophosphamide alternating with vincristine, topotecan, and cyclophosphamide for intermediate-risk rhabdomyosarcoma: children's oncology group study D9803.
19770373 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009 Nov 1 : 27(31)5182-8 PMCID:PMC2773476 -
Borinstein SC, Pollard J, Winter L, Hawkins DSPegfilgrastim for prevention of chemotherapy-associated neutropenia in pediatric patients with solid tumors.
19484756 Pediatric blood & cancer, 2009 Sept. : 53(3)375-8 -
Rodeberg DA, Stoner JA, Hayes-Jordan A, Kao SC, Wolden SL, Qualman SJ, Meyer WH, Hawkins DSPrognostic significance of tumor response at the end of therapy in group III rhabdomyosarcoma: a report from the children's oncology group.
19470937 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009 Aug 1 : 3705-11 -
Rodeberg DA, Stoner JA, Hayes-Jordan A, Kao SC, Wolden SL, Qualman SJ, Meyer WH, Hawkins DSPrognostic significance of tumor response at the end of therapy in group III rhabdomyosarcoma: a report from the children's oncology group.
19470937 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009 Aug 1 : 27(22)3705-11 PMCID:PMC3020959 -
Hawkins DS, Conrad EU 3rd, Butrynski JE, Schuetze SM, Eary JF[F-18]-fluorodeoxy-D-glucose-positron emission tomography response is associated with outcome for extremity osteosarcoma in children and young adults.
19517457 Cancer, 2009 Aug 1 : 115(15)3519-25 PMCID:PMC2716419 -
Imran H, Enders F, Krailo M, Sim F, Okuno S, Hawkins D, Neglia J, Randall RL, Womer R, Mascarenhas L, Arndt CAEffect of time to resumption of chemotherapy after definitive surgery on prognosis for non-metastatic osteosarcoma.
19255220 The Journal of bone and joint surgery. American volume, 2009 Mar 1 : 91(3)604-12 PMCID:PMC2701597 -
Cengiz P, Zemlan F, Ellenbogen R, Hawkins D, Zimmerman JJCerebrospinal fluid cleaved-tau protein and 9-hydroxyoctadecadienoic acid concentrations in pediatric patients with hydrocephalus.
18679140 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2008 Sept. : 9(5)524-9 -
Rodriguez NI, Hoots WK, Koshkina NV, Morales-Arias JA, Arndt CA, Inwards CY, Hawkins DS, Munsell MF, Kleinerman ESCOX-2 expression correlates with survival in patients with osteosarcoma lung metastases.
18797196 Journal of pediatric hematology/oncology, 2008 July : 30(7)507-12 PMCID:PMC2771732 -
Wirojanan J, Kraff J, Hawkins DS, Laird C, Gane LW, Angkustsiri K, Tassone F, Hagerman RJTwo boys with fragile x syndrome and hepatic tumors.
18376289 Journal of pediatric hematology/oncology, 2008 March : 30(3)239-41 -
Borinstein SC, Xu M, Hawkins DSMethemoglobinemia and hemolytic anemia caused by rasburicase administration in a newly diagnosed child with Burkitt lymphoma/leukemia.
17387701 Pediatric blood & cancer, 2008 Jan. : 50(1)189 -
Arndt CA, Hawkins DS, Meyer WH, Sencer SF, Neglia JP, Anderson JRComparison of results of a pilot study of alternating vincristine/doxorubicin/cyclophosphamide and etoposide/ifosfamide with IRS-IV in intermediate risk rhabdomyosarcoma: a report from the Children's Oncology Group.
17091486 Pediatric blood & cancer, 2008 Jan. : 50(1)33-6 -
Douglas JG, Arndt CA, Hawkins DSDelayed radiotherapy following dose intensive chemotherapy for parameningeal rhabdomyosarcoma (PM-RMS) of childhood.
17368885 European journal of cancer (Oxford, England : 1990), 2007 April : 43(6)1045-50 -
Greene S, Hawkins DS, Rutledge JC, Tsuchiya KD, Douglas J, Ellenbogen RG, Avellino AMPediatric intradural extramedullary synovial sarcoma: case report.
17277671 Neurosurgery, 2006 Dec. : E1339; discussion E1339 -
Hawkins DS, Bradfield S, Whitlock JA, Krailo M, Franklin J, Blaney SM, Adamson PC, Reaman GTopotecan by 21-day continuous infusion in children with relapsed or refractory solid tumors: a Children's Oncology Group study.
16435380 Pediatric blood & cancer, 2006 Nov. : 47(6)790-4 -
Taylor JA, Winter L, Geyer LJ, Hawkins DSOral outpatient chemotherapy medication errors in children with acute lymphoblastic leukemia.
16909415 Cancer, 2006 Sep 15 : 107(6)1400-6 -
Morgan HD, Cizik AM, Leopold SS, Hawkins DS, Conrad EU 3rdSurvival of tumor megaprostheses replacements about the knee.
16906094 Clinical orthopaedics and related research, 2006 Sept. : 45039-45 -
Hawkins DS, Schuetze SM, Butrynski JE, Rajendran JG, Vernon CB, Conrad EU 3rd, Eary JF[18F]Fluorodeoxyglucose positron emission tomography predicts outcome for Ewing sarcoma family of tumors.
16314643 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005 Dec 1 : 23(34)8828-34 -
Cole PD, Drachtman RA, Smith AK, Cate S, Larson RA, Hawkins DS, Holcenberg J, Kelly K, Kamen BAPhase II trial of oral aminopterin for adults and children with refractory acute leukemia.
16299240 Clinical cancer research : an official journal of the American Association for Cancer Research, 2005 Nov 15 : 11(22)8089-96 PMCID:PMC2906753 -
Gordon N, Arndt CA, Hawkins DS, Doherty DK, Inwards CY, Munsell MF, Stewart J, Koshkina NV, Kleinerman ESFas expression in lung metastasis from osteosarcoma patients.
16282894 Journal of pediatric hematology/oncology, 2005 Nov. : 27(11)611-5 -
Spiller SE, Hawkins DS, Finn LS, Sze RW, Sybert VMetastatic malignant melanoma presenting as pancytopenia in a three-year-old boy.
15800910 Pediatric blood & cancer, 2005 July : 45(1)60-3 -
Barker LM, Pendergrass TW, Sanders JE, Hawkins DSSurvival after recurrence of Ewing's sarcoma family of tumors.
15781881 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005 Jul 1 : 23(19)4354-62 -
Schuetze SM, Rubin BP, Vernon C, Hawkins DS, Bruckner JD, Conrad EU 3rd, Eary JFUse of positron emission tomography in localized extremity soft tissue sarcoma treated with neoadjuvant chemotherapy.
15578712 Cancer, 2005 Jan 15 : 103(2)339-48 -
Hawkins DSTransatlantic collaboration in pediatric oncology: now is the time.
15591895 Journal of pediatric hematology/oncology, 2004 Dec. : 26(12)783-4 -
Thomson B, Park JR, Felgenhauer J, Meshinchi S, Holcenberg J, Geyer JR, Avramis V, Douglas JG, Loken MR, Hawkins DSToxicity and efficacy of intensive chemotherapy for children with acute lymphoblastic leukemia (ALL) after first bone marrow or extramedullary relapse.
15382275 Pediatric blood & cancer, 2004 Oct. : 571-9 -
Hawkins DS, Park JR, Thomson BG, Felgenhauer JL, Holcenberg JS, Panosyan EH, Avramis VIAsparaginase pharmacokinetics after intensive polyethylene glycol-conjugated L-asparaginase therapy for children with relapsed acute lymphoblastic leukemia.
15328169 Clinical cancer research : an official journal of the American Association for Cancer Research, 2004 Aug 15 : 5335-41 -
McCune JS, Friedman DL, Schuetze S, Blough D, Magbulos M, Hawkins DSInfluence of age upon Ifosfamide-induced nephrotoxicity.
15049014 Pediatric blood & cancer, 2004 May : 42(5)427-32 -
Bradfield SM, Douglas JG, Hawkins DS, Sanders JE, Park JRFractionated low-dose radiotherapy after myeloablative stem cell transplantation for local control in patients with high-risk neuroblastoma.
15022296 Cancer, 2004 Mar 15 : 100(6)1268-75 -
Finn LS, Hawkins DS, Rutledge JC, Patterson KEvaluation of early marrow response in childhood aneuploid acute lymphoblastic leukemia: flow cytometric DNA analysis versus standard morphology.
15255034 Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, 2004 Jan. : 7(1)39-47 -
Hawkins DS, Arndt CAPattern of disease recurrence and prognostic factors in patients with osteosarcoma treated with contemporary chemotherapy.
14635080 Cancer, 2003 Dec 1 : 98(11)2447-56 -
Smith SC, Lindsley SK, Felgenhauer J, Hawkins DS, Douglas JGIntensive induction chemotherapy and delayed irradiation in the management of parameningeal rhabdomyosarcoma.
14528099 Journal of pediatric hematology/oncology, 2003 Oct. : 25(10)774-9 -
Wright JA, Bradfield SM, Park JR, Hawkins DSProlonged survival after invasive aspergillosis: a single-institution review of 11 cases.
12679641 Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology, 2003 April : 286-91 -
Park JR, Coughlin J, Hawkins D, Friedman DL, Burns JL, Pendergrass TCiprofloxacin and amoxicillin as continuation treatment of febrile neutropenia in pediatric cancer patients.
12461792 Medical and pediatric oncology, 2003 Feb. : 40(2)93-8 -
Hawkins DS, Felgenhauer J, Park J, Kreissman S, Thomson B, Douglas J, Rowley SD, Gooley T, Sanders JE, Pendergrass TWPeripheral blood stem cell support reduces the toxicity of intensive chemotherapy for children and adolescents with metastatic sarcomas.
12216105 Cancer, 2002 Sep 15 : 1354-65 -
Mansky PJ, Liewehr DJ, Steinberg SM, Chrousos GP, Avila NA, Long L, Bernstein D, Mackall CL, Hawkins DS, Helman LJTreatment of metastatic osteosarcoma with the somatostatin analog OncoLar: significant reduction of insulin-like growth factor-1 serum levels.
12218590 Journal of pediatric hematology/oncology, 2002 Aug. : 24(6)440-6 -
Hawkins DS, Rajendran JG, Conrad EU 3rd, Bruckner JD, Eary JFEvaluation of chemotherapy response in pediatric bone sarcomas by [F-18]-fluorodeoxy-D-glucose positron emission tomography.
12115361 Cancer, 2002 Jun 15 : 94(12)3277-84
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Presentations Title Event Location Date Successes and challenges in pediatric cancer: the Children’s Oncology Group (COG) perspective Biopathology Center at Nationwide Children’s Hospital, Columbus, OH 2022 Successes and challenges in pediatric cancer: the Children’s Oncology Group (COG) perspective American Medical School Pediatric Department Chair Annual Meeting Virtual 2022 Update on the medical management of osteosarcoma 2021 Pakistan Orthopedic Oncology Virtual Conference Virtual 2021 Evolution of risk stratification of rhabdomyosarcoma and its role in management Pakistan Society of Pediatric Oncology Symposium Virtual 2021 Pediatric early phase drug development: the world is wide enough for POETIC and COG Pediatric Oncology Experimental Therapeutics Investigator’s Consortium (POETIC) Fall 2021 Meeting Virtual 2021 NCI Molecular Characterization Protocol and Project:EveryChild approach National Cancer Institute Childhood Cancer Data Initiative Annual Symposium Virtual 2021 Current and future NCI-COG strategies for precision medicine in pediatric rhabdomyosarcoma Summer’s Way Rhabdomyosarcoma Workshop Virtual 2021 Biology and treatment of rhabdomyosarcoma: lessons from the Children's Oncology Group Norton Children’s Hospital Pediatric Grand Rounds Virtual 2021 Successes and challenges in pediatric cancer: the Children’s Oncology Group (COG) perspective Evan Dunbar Lectureship Louisville, KY 2021 Successes and challenges in pediatric cancer: the Children’s Oncology Group (COG) perspective Australian and New Zealand Children’s Haematology/Oncology Group (ANZCHOG) Annual Scientific Meeting Virtual 2021 COG perspective on the impact of COVID-19 on pediatric oncology clinical trials and implications for the future American Society of Clinical Oncology Annual Meeting Virtual 2021 Informing pediatric clinical research strategies and drug development through RWE Food and Drug Administration, Center for Drug Evaluation and Research, Pediatric Oncology Subcommittee of the Oncologic Drugs Advisory Committee Meeting Virtual 2021 Incorporating Pediatric PRO-CTCAE in NCTN clinical trials Food and Drug Administration, Center for Drug Evaluation and Research, Pediatric Oncology Subcommittee of the Oncologic Drugs Advisory Committee Meeting Virtual 2021 Successes and challenges in pediatric cancer: the Children’s Oncology Group (COG) perspective Science of Childhood Cancer, St. Jude Cancer Research Hospital Virtual 2021 Successes and challenges in pediatric cancer: the Children’s Oncology Group (COG) perspective University of Iowa Stead Family Department of Pediatric Grand Rounds Virtual 2021 Children’s Oncology Group strategies for treatment of rhabdomyosarcoma 5th Pediatric Hematology & Oncology Updates King Faisal Specialist Hospital & Research Center, Saudi Arabia,Saudi Arabia (virtual) 2020 Perspectives from the new COG Group Chair Coalition Against Childhood Cancer 8th Annual Summit On-line 2020 The past, present, and future of maintenance chemotherapy in rhabdomyosarcoma 2020 Pediatric Soft Tissue Sarcoma Conference Houston, TX 2020 Children’s Oncology Group Soft Tissue Sarcoma Committee update to EpSSG European Paediatric Soft Tissue Sarcoma Meeting London, United Kingdom 2019 Multidisciplinary management of parameningeal rhabdomyosarcoma: point of view of the pediatrician International Society of Paediatric Oncology Lyon, France 2019 Lessons from the COG Soft Tissue Sarcoma Committee for international collaboration European Society for Paediatric Oncology Prague, Czech Republic 2019 DICER1 Mutations in Sarcomas European Society for Paediatric Oncology Prague, Czech Republic 2019 Children’s Oncology Group Strategies for Ewing sarcoma treatment Grupo de America Latina de Oncologia Pediatrica Buenos Aires, Argentina 2019 2019 update from Children’s Oncology Group Soft Tissue Sarcoma Committee American Society of Pediatric Hematology/Oncology New Orleans, LA 2019 Chemotherapy for rhabdomyosarcoma: the Children’s Oncology Group perspective West Coast Sarcoma Conference Vancouver, British Columbia 2019 Clinical trials past, present, and future for rhabdomyosarcoma: the Children’s Oncology Group perspective Ruth Rappaport Annual Meeting in Pediatric Oncology, Northern Israel Haifa, Israel 2019 Clinical trials past, present, and future for rhabdomyosarcoma: the Children’s Oncology Group perspective Japanese Society of Pediatric Hematology/Oncology Kyoto, Japan 2018 Discussant, Plenary Session American Society of Clinical Oncology Chicago, IL 2018 The Past and Present State of Treatment for Rhabdomyosarcoma: the COG perspective Summer’s Way Rhabdomyosarcoma Workshop Denver, CO 2018 Children’s Oncology Group Update on Soft Tissue Sarcoma Clinical Trials European Paediatric Soft Tissue Sarcoma Meeting Lyon, France 2017 Lessons Learned in the Search of New Treatment for Pediatric Sarcomas New Horizons in Young Adult Oncology Symposium Cincinnati, Ohio 2017 Children’s Oncology Group Update on Soft Tissue Sarcoma Clinical Trials European Paediatric Soft Tissue Sarcoma Meeting Copenhagen, Denmark 2017 Biology and Treatment of Rhabdomyosarcoma in the Genomics Age Hematology/Oncology Grand Rounds, Children’s National Medical Center Washington, DC 2017 Risk Stratification for Rhabdomyosarcoma in the Modern Era Cooperative Weichteilsarkom Studiengruppe, European Paediatric Soft Tissue Sarcoma, and Children’s Oncology Group Soft Tissue Sarcoma Meeting Stuttgart, Germany 2016 Treating Pediatric Soft Tissue Sarcomas in the Genomic and Targeted Therapy Age: the COG Approach Soft Tissue Sarcoma in the Young: Expectations, Achievements and Perspectives Stuttgart, Germany 2016 Children’s Oncology Group Update on Soft Tissue Sarcoma Clinical Trials European Paediatric Soft Tissue Sarcoma Meeting Barcelona, Spain 2016 Very high risk alveolar rhabdomyosarcoma: comparative analysis of Children’s Oncology Group European Paediatric Soft Tissue Sarcoma studies European Paediatric Soft Tissue Sarcoma Meeting Barcelona, Spain 2016 Children’s Oncology Group Update on Soft Tissue Sarcoma Clinical Trials European Paediatric Soft Tissue Sarcoma Meeting Amsterdam, The Netherlands 2015 Children’s Oncology Group Update on Soft Tissue Sarcoma Clinical Trials European Paediatric Soft Tissue Sarcoma Meeting Sutton, United Kingdom 2015 Children’s Oncology Group: Future Plans and Ongoing Studies in Ewing Sarcoma Sarkomkonferenz Münster, Germany 2015 Children’s Oncology Group Update on Soft Tissue Sarcoma Clinical Trials European Paediatric Soft Tissue Sarcoma Meeting Lyon, France 2014 Children’s Oncology Group Approach to Treatment of Rhabdomyosarcoma Pablove Foundation International Think Tank Los Angeles, CA 2014 Rhabdomyosarcoma: How many and how to treat? Joseph McBride Memorial Sarcoma Lecture, Inova Comprehensive Cancer & Research Institute Fairfax, VA 2014 Children’s Oncology Group Update on Soft Tissue Sarcoma Clinical Trials European Paediatric Soft Tissue Sarcoma Meeting Milan, Italy 2014 Rhabdomyosarcoma: How many and how to treat? Grand Rounds, St. Jude Children’s Research Hospital Memphis, TN 2014 What Children with Rhabdomyosarcoma Have Taught Me Pediatric Grand Rounds, Alfred I. duPont Hospital for Children Wilmington, DE 2013 - 2013 COG approach to identification and introduction of new/targeted therapies in RMS/STS European Paediatric Soft Tissue Sarcoma Meeting Paris, France, Mar 22, 2013 Rhabdomyosarcoma: How many and how to treat Texas Childrens Cancer Center Houston, TX Feb 14, 2013 What children have taught me about rhabdomyosarcoma Pediatric Grand Rounds, Childrens Hospital at Montefiore Bronx, NY Jan 30, 2013 From Seattle to Sydney: lessons from selected pediatric sarcoma cases Pediatric Oncology Conference Sydney, Australia Oct 8, 2012 Childrens Oncology Group update on soft tissue sarcoma clinical trials International Symposium on the Biology and Treatment of the Pediatric Soft Tissue Sarcomas Padova, Italy Dec 6, 2011 -
Grant Title Grantor Amount Award Date COG NCTN Integrated Translational Science Center for Hematopoietic Malignancies in Children National Cancer Institute 2020 - 2025 COG NCORP Research Base National Cancer Institute 2020 - 2025 COG NCTN Network Group Operations Center Grant National Cancer Institute $119,586,932 2020 - 2025
Overview
- Board Certification(s)
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Pediatric Hematology-Oncology
- Medical/Professional School
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Harvard Medical School, Boston, MA
- Residency
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University of Washington School of Medicine, Seattle, WA
- Clinical Interests
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Sarcomas, clinical trials
- Research Description
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The goals of the Children's Oncology Group are to: 1) design and conduct collaborative clinical-translational studies for children with cancer that build on an increasing understanding of the molecular basis for pediatric malignancies, bridge gaps in knowledge, and have the highest potential to improve outcome for all childhood cancer patients; 2) conduct research that lessens the morbidity of cancer therapy and improves the quality of life for children throughout their care, spanning diagnosis, treatment and survivorship; 3) collect and highly annotate biospecimens from all children with cancer, leveraging COG’s nearly population based research enterprise, to provide the foundation for discovery of the molecular basis of all childhood cancers, no matter how rare, and accelerate the most promising translational research efforts conducted at laboratories around the world
- Research Focus Area
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Refractory and recurrent cancer, Sarcomas, Thyroid Cancer, Cardiotoxicity prevention & prediction, Cancer